Mechanically evoked sensory and motor responses to dynamic compression of the ulnar nerve.

Abstract:

:Mechanical deformation of a peripheral nerve can evoke action potentials in sensory and motor axons. The generation of these impulses with brief stimuli (<0.5 s) and their relationship to the deformation conditions have not been systematically studied in human subjects. Controlled compression stimuli over a range of amplitudes, durations, and loading rates were delivered to the ulnar nerve at the medial epicondyle in awake human subjects. Compound muscle action potentials were recorded from the first dorsal interosseous muscle. Subjects rated the magnitude of evoked paresthesias. Mechanically evoked motor and sensory responses varied linearly with the magnitude (P < 0.001) and rate of deformation (P < 0.01), but not the duration, and occurred only during the compression phase. Cutaneous axons had lower mechanical thresholds than motor axons. We relate these findings to the viscoelastic properties of peripheral nerves and differences in biophysical properties of cutaneous and motor axons.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Clarke EC,McNulty PA,Macefield VG,Bilston LE

doi

10.1002/mus.20701

subject

Has Abstract

pub_date

2007-03-01 00:00:00

pages

303-11

issue

3

eissn

0148-639X

issn

1097-4598

journal_volume

35

pub_type

杂志文章
  • The effect of isometric short-term electrical stimulation on denervated muscle.

    abstract::Electrical stimulation was applied daily for 20 minutes to denervated rabbit extensor digitorum longus muscle. One group was stimulated with short tetani, another with 1-Hz frequency, using isometric contractions for both. Tetanic stimulation induced severe fibrosis and is harmful to denervated muscle. One Hertz stimu...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880100206

    authors: Nix WA,Dahm M

    更新日期:1987-02-01 00:00:00

  • Influence of body mass index on median nerve function, carpal canal pressure, and cross-sectional area of the median nerve.

    abstract::Obese individuals have slowed conduction in the median nerve across the wrist, but the mechanism for this is not established. This case-control study of 27 obese subjects and 16 thin subjects was designed to test the hypothesis that obese individuals have higher carpal canal pressures and more median nerve swelling th...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20125

    authors: Werner RA,Jacobson JA,Jamadar DA

    更新日期:2004-10-01 00:00:00

  • Differences between young and older women in maximal force, force fluctuations, and surface EMG during isometric knee extension and elbow flexion.

    abstract::The loss of muscle strength with aging appears to be greater in the lower than upper limbs, but strength and its neural control have never been compared in the same population of individuals in both upper and lower limbs. The aim of this study was to investigate differences between eight young (20-31 years) and eight ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20151

    authors: Bazzucchi I,Felici F,Macaluso A,De Vito G

    更新日期:2004-11-01 00:00:00

  • The effect of fatigue on knee position sense is not dependent upon the muscle group fatigued.

    abstract:INTRODUCTION:Muscle fatigue could have a greater impact on position sense when antagonists of the movement are fatigued. Hence, this study aimed to compare the effects of antagonist and agonist exercise-induced muscle fatigue on knee joint position sense. METHODS:This within-subjects repeated-measures study included 4...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.22018

    authors: Ribeiro F,Venâncio J,Quintas P,Oliveira J

    更新日期:2011-08-01 00:00:00

  • L1 radiculopathy mimicking meralgia paresthetica: a case report.

    abstract::L1 radiculopathy is very rare and difficult to diagnose with needle electromyography. A patient presented with pain and hypesthesia on the anterolateral aspect of the left thigh. Nerve conduction studies and needle electromyography were normal, except for the quadratus lumborum and iliopsoas muscles, which showed abno...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21601

    authors: Yang SN,Kim DH

    更新日期:2010-04-01 00:00:00

  • Serum CK, calcium, magnesium, and oxidative phosphorylation in mdx mouse muscular dystrophy.

    abstract::Serum creatine kinase (CK) activity, calcium (Ca) and magnesium (Mg) contents of skeletal muscle and isolated mitochondria, as well as oxidative phosphorylation of X-linked muscular dystrophic (mdx) mice were compared with normal control animals at ages 5, 10, and 23 weeks. Serum CK is elevated in mdx mice at all ages...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880110809

    authors: Glesby MJ,Rosenmann E,Nylen EG,Wrogemann K

    更新日期:1988-08-01 00:00:00

  • Interspike interval analysis in a patient with peripheral nerve hyperexcitability and potassium channel antibodies.

    abstract::Neuromyotonia or Isaacs' syndrome is a rare peripheral nerve hyperexcitability disorder caused by antibodies against potassium channels of myelinated axons. We present the high-density surface electromyographic (EMG) recordings of a patient with fasciculations and cramps due to neuromyotonia. To characterize the time ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20849

    authors: Kleine BU,Stegeman DF,Drost G,Zwarts MJ

    更新日期:2008-02-01 00:00:00

  • Spontaneous and evoked ectopic discharges recorded from single human axons.

    abstract::A quantitative assessment was made of the firing characteristics of repetitive axonal discharges encountered during microneurographic recordings from human peripheral nerves. Spontaneous activity was recorded from 16 single axons using tungsten microelectrodes inserted percutaneously into fascicles of the median or pe...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199804)21:4<461::aid-mus4>

    authors: Macefield VG

    更新日期:1998-04-01 00:00:00

  • Inaccurate projection of rat soleus motoneurons: a comparison of nerve repair techniques.

    abstract::The objectives of this study were 1) to determine the degree to which soleus motoneurons find their appropriate target following crush and transection injuries to the sciatic nerve, and 2) to determine whether repair of a transected nerve with a silicone tube leads to greater specificity of reinnervation and recovery ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199701)20:1<29::aid-mus4>3

    authors: Bodine-Fowler SC,Meyer RS,Moskovitz A,Abrams R,Botte MJ

    更新日期:1997-01-01 00:00:00

  • Motor involvement in acute herpes zoster.

    abstract::Motor involvement in acute herpes zoster is considered rare, but its incidence is unknown. In a sample of 40 patients with acute herpes zoster of varying severity, an abnormal electromyogram (EMG) (fibrillation, positive waves, high-frequency discharges) was found in 21 (53%), suggesting extension of inflammation to t...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199711)20:11<1433::aid-mus

    authors: Haanpää M,Häkkinen V,Nurmikko T

    更新日期:1997-11-01 00:00:00

  • Correlating serum micrornas and clinical parameters in amyotrophic lateral sclerosis.

    abstract:INTRODUCTION:Amyotrophic lateral sclerosis (ALS) is a debilitating neurologic disorder with poor survival rates and no clear biomarkers for disease diagnosis and prognosis. METHODS:We compared serum microRNA (miRNA) expression from patients with ALS with healthy controls and patients with multiple sclerosis and Alzhei...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.26106

    authors: Raheja R,Regev K,Healy BC,Mazzola MA,Beynon V,Von Glehn F,Paul A,Diaz-Cruz C,Gholipour T,Glanz BI,Kivisakk P,Chitnis T,Weiner HL,Berry JD,Gandhi R

    更新日期:2018-08-01 00:00:00

  • Urinary retention and sympathetic sphincter obstruction in axonal Guillain-Barré syndrome.

    abstract::A 62-year-old woman with axonal Guillain-Barré syndrome developed weakness and urinary retention simultaneously. The retention failed to recover for 10 months even after she regained the ability to walk. The patient exhibited no postural hypotension. Videourodynamics showed that the retention was caused not by the bla...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20639

    authors: Sakakibara R,Uchiyama T,Tamura N,Kuwabara S,Asahina M,Hattori T

    更新日期:2007-01-01 00:00:00

  • Type IV collagen and its degradation in paralyzed human muscle: effect of functional electrical stimulation.

    abstract::The purpose of this study was to evaluate the effects of spinal cord injury (SCI) and functional electrical stimulation (FES) of paralyzed muscles on type IV collagen content and proteins involving its degradation, which is initiated by matrix metalloproteinase (MMP)-2 and -9 and regulated by their tissue inhibitors (...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(200004)23:4<580::aid-mus18

    authors: Koskinen SO,Kjaer M,Mohr T,Sørensen FB,Suuronen T,Takala TE

    更新日期:2000-04-01 00:00:00

  • Normal myoblast injections provide genetic treatment for murine dystrophy.

    abstract::A treatment has been developed to alleviate muscle weakness in murine dystrophy. Cultured myoblasts from genetically normal mouse embryos were injected into the right soleus of 20-day-old normal or dystrophic mice. Hosts and donors were immunocompatible but exhibited different genotype markers. Donor cells produced GP...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880110602

    authors: Law PK,Goodwin TG,Wang MG

    更新日期:1988-06-01 00:00:00

  • Invited review: peripheral neuropathy in Sjogren's syndrome.

    abstract::Our experience and review of the literature reveal that Sjogren's syndrome (SS) is an important, poorly recognized cause of peripheral neuropathy. Several forms of peripheral nerve dysfunction occur in SS including trigeminal sensory neuropathy, mononeuropathy multiplex, distal sensory neuropathy, distal sensorimotor ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/mus.880130703

    authors: Kaplan JG,Rosenberg R,Reinitz E,Buchbinder S,Schaumburg HH

    更新日期:1990-07-01 00:00:00

  • Interaction of monoclonal antibodies to Torpedo acetylcholine receptor with the receptor of skeletal muscle.

    abstract::Several monoclonal antibodies (mcAbs) elicited against the nicotinic acetylcholine receptor (AChR) from Torpedo react also with skeletal muscle AChR. Such mcAbs were used to define antigenic determinants on muscle AChR and to elucidate their effect on muscle AChR functions. Primary chick muscle cultures were used as a...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880060410

    authors: Souroujon MC,Mochly-Rosen D,Gordon AS,Fuchs S

    更新日期:1983-05-01 00:00:00

  • Repetitive nerve stimulation of facial muscles in MuSK antibody-positive myasthenia gravis.

    abstract::To better define electrophysiological abnormalities in myasthenia gravis (MG) patients with muscle-specific tyrosine kinase (MuSK) antibodies (Ab), we compared electrophysiological features of 14 MuSK Ab-positive, 73 acetylcholine receptor antibody (AChR Ab)-positive, and 22 MuSK and AChR Ab-negative (seronegative) pa...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20498

    authors: Oh SJ,Hatanaka Y,Hemmi S,Young AM,Scheufele ML,Nations SP,Lu L,Claussen GC,Wolfe GI

    更新日期:2006-04-01 00:00:00

  • Nerve, muscle, and neuromuscular junction electrophysiology at high temperature.

    abstract::Although the effect of low temperature on the peripheral nervous system has been systematically studied, the effect of high temperature has not. We investigated the effect of elevating limb temperature from 32 degrees C to 42 degrees C by performing sequential motor studies, antidromic sensory studies, and 3-Hz repeti...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199704)20:4<431::aid-mus5>

    authors: Rutkove SB,Kothari MJ,Shefner JM

    更新日期:1997-04-01 00:00:00

  • Ulnar neuropathy and dystonic flexion of the fourth and fifth digits: clinical correlation in musicians.

    abstract::Peripheral nerve lesions are sometimes associated with focal dystonia. We diagnosed ulnar neuropathy in 28 of 73 (40%) cases of occupational cramp in musicians. Focal slowing of ulnar conduction across the elbow was identified in 15 of 19 (79%) patients using the near nerve technique and in 5 of 17 (29%) patients usin...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880190403

    authors: Charness ME,Ross MH,Shefner JM

    更新日期:1996-04-01 00:00:00

  • Electrophysiology in chronic inflammatory demyelinating polyneuropathy with IGIV.

    abstract::Patients with chronic inflammatory demyelinating polyneuropathy (CIDP) received immune globulin intravenous, 10% caprylate/chromatography purified (IGIV-C, Gamunex; n=59) or placebo (n=58) every 3 weeks for up to 24 weeks (first period) in a randomized, double-blind, parallel-group, response-conditional, crossover stu...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/mus.21236

    authors: Bril V,Katzberg H,Donofrio P,Banach M,Dalakas MC,Deng C,Hanna K,Hartung HP,Hughes RA,Latov N,Merkies IS,van Doorn PA,ICE Study Group.

    更新日期:2009-04-01 00:00:00

  • Effect of maximal voluntary contraction on the amplitude of the compound muscle action potential: implications for the interpolated twitch technique.

    abstract::The compound muscle action potential (M(MAX)) during a maximal voluntary contraction (MVC) may be measured to determine if the motor nerve has been supramaximally stimulated during the interpolated twitch technique (ITT). Ten males performed isometric knee extension MVCs. M(MAX) for the vastus medialis was recorded du...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21692

    authors: Berger MJ,Watson BV,Doherty TJ

    更新日期:2010-10-01 00:00:00

  • Congenital canine myasthenia gravis: II. Acetylcholine receptor metabolism.

    abstract::Acetylcholine receptor (AChR) metabolism was studied in muscle from juvenile and adult dogs with congenital myasthenia gravis (CMG) and their unaffected littermates. Although the amount of AChR in the junctional region of innervated CMG muscle fibers was 25% of normal, or less, denervation of CMG fibers resulted in th...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880070905

    authors: Oda K,Lennon VA,Lambert EH,Palmer AC

    更新日期:1984-11-01 00:00:00

  • Proteins of muscle subcellular fractions in Duchenne progressive muscular dystrophy stained with "stains-all" cationic carbocyanine dye and with Coomassie Blue.

    abstract::The protein compositions of subcellular fractions of muscle obtained from 17 Duchenne dystrophy patients, 15 disease controls (10 different primary myopathies, 5 spinal muscular atrophy patients), and 10 normals were examined by polyacrylamide gel electrophoresis. The gels were stained with Coomassie Brilliant Blue an...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880120404

    authors: Niebroj-Dobosz I,Kornguth S,Schutta H,Siegel FL,Hausmanowa-Petrusewicz I

    更新日期:1989-04-01 00:00:00

  • Contractile speed and fatigue of adductor pollicis muscle in multiple sclerosis.

    abstract::The purpose of the study was to investigate differences in contractile speed, force, and fatigability of the adductor pollicis muscle between 12 patients with multiple sclerosis (MS) and 8 sedentary control subjects matched for age and gender. There were no differences between the patients with MS and control subjects...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.1129

    authors: de Ruiter CJ,Jongen PJ,van der Woude LH,de Haan A

    更新日期:2001-09-01 00:00:00

  • Recombinant growth hormone treatment of amyotrophic lateral sclerosis.

    abstract::Based on the known trophic effects of growth hormone (GH) on nerve and muscle 75 patients with ALS were treated for up to 18 months with synthetic human growth hormone (Protropin) or a placebo. The course of ALS was assessed serially using a quantitative (TQNE) neuromuscular and manual exam (MRC) and laboratory chemis...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1002/mus.880160608

    authors: Smith RA,Melmed S,Sherman B,Frane J,Munsat TL,Festoff BW

    更新日期:1993-06-01 00:00:00

  • Myasthenia gravis and premature ovarian failure.

    abstract::We describe a patient who developed seropositive myasthenia gravis 16 years after she was diagnosed with autoimmune premature ovarian failure with antibodies to the receptor for follicle-stimulating hormone (FSH). Although thymectomy led to improvement of her myasthenic symptoms, menses did not resume. Such combined s...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20067

    authors: Ryan MM,Jones HR Jr

    更新日期:2004-08-01 00:00:00

  • Interaction of thyroid state and denervation on skeletal myosin heavy chain expression.

    abstract::The goal of this study was to examine the effects of altered thyroid state and denervation (Den) on skeletal myosin heavy chain (MHC) expression in the plantaris and soleus muscles. Rats were subjected to unilateral denervation (Den) and randomly assigned to one of three groups: (1) euthyroid; (2) hyperthyroid; (3) an...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199712)20:12<1487::aid-mus

    authors: Haddad F,Arnold C,Zeng M,Baldwin K

    更新日期:1997-12-01 00:00:00

  • Reference jitter values for concentric needle electrodes in voluntarily activated extensor digitorum communis and orbicularis oculi muscles.

    abstract::The aim of this study was to estimate normal jitter in voluntarily activated extensor digitorum communis (EDC) and orbicularis oculi (OOc) muscles using a disposable concentric needle electrode (CNE). The EDC of 67 normal subjects (22 males and 45 females, mean age 35.5 +/- 10.2 years) and the OOc of 50 normal subject...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21043

    authors: Kouyoumdjian JA,Stålberg EV

    更新日期:2008-06-01 00:00:00

  • Diagnostic value of nerve biopsy for atypical chronic inflammatory demyelinating polyneuropathy: evaluation of eight cases.

    abstract::The diagnosis of chronic inflammatory demyelinating polyneuropathy (CIDP) relies primarily on clinical and electrophysiologic examination, but the nerve biopsy findings may be supportive, especially in atypical cases. In order to define the usefulness of nerve biopsy in this disease, we retrospectively studied 44 cons...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.10348

    authors: Vallat JM,Tabaraud F,Magy L,Torny F,Bernet-Bernady P,Macian F,Couratier P

    更新日期:2003-04-01 00:00:00

  • Multiple descending corticospinal volleys demonstrated by changes of the wrist flexor H-reflex to magnetic motor cortex stimulation in intact human subjects.

    abstract::To study noninvasively multiple descending volleys on alpha motoneurons, we used a 30-50% maximum H-reflex in the wrist flexor muscle conditioned by a subthreshold magnetic stimulus of the contralateral motor cortex as a parameter of motoneuronal excitability in seven neurologically healthy subjects. The time interval...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880160406

    authors: van der Linden C,Bruggeman R

    更新日期:1993-04-01 00:00:00