Effects of prolonged repetitive stimulation of median, ulnar and peroneal nerves.

Abstract:

:It is important to know the effects of prolonged repetitive nerve stimulation (RNS) when it is used in neurophysiological studies. RNS with up to 100 supramaximal stimuli was given to the median, ulnar, and peroneal nerves of normal subjects and the ulnar nerves of subjects with early amyotrophic lateral sclerosis (ALS), recording evoked compound muscle action potentials (CMAPs). In all nerves, there was a decline in the CMAP area and a decrease in CMAP duration. For the peroneal nerve there was a decline in the CMAP amplitude, but a similar decline was not seen in the median or ulnar nerves. Cooling of the muscles resulted in decrement of both the amplitude and area with RNS. In ALS subjects, CMAP amplitude and area both declined after RNS of the ulnar nerve. In this study we describe the changes in CMAP with prolonged RNS among commonly tested normal nerves. Our findings have important implications with regard to RNS.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Baumann F,Henderson RD,Tremayne F,Hutchinson N,McCombe PA

doi

10.1002/mus.21604

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

785-93

issue

6

eissn

0148-639X

issn

1097-4598

journal_volume

41

pub_type

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