Immunohistochemical characterization of human masseter muscle spindles.

Abstract:

:An enzyme- and immunohistochemical study has been performed on human masseter muscle spindles. Antibodies selective for different myosin heavy chain (MHC) isoforms and M-band proteins (M-protein, myomesin, and MM-CK) were used. The expression of these proteins was determined in the different intrafusal fiber types. Nuclear bag1 and nuclear bag2 fibers expressed predominantly slow-twitch and slow-tonic MHCs. The bag2 fibers in addition contained fetal MHC. Nuclear chain fibers coexpressed embryonic, fetal, and fast-twitch MHCs. The bag2 and chain fibers contained all three M-band proteins, whereas the bag1 fibers contained only myomesin. In general the MHC expression in the human masseter intrafusal fiber types was similar to that previously reported for limb muscles in man as well as for limb and masseter muscles in other species. However, the number of intrafusal fibers per spindle was unusually high (up to 36). This reinforces the idea that masseter muscle spindles have a strong proprioceptive impact during the control of jaw movements.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Eriksson PO,Butler-Browne GS,Thornell LE

doi

10.1002/mus.880170105

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

31-41

issue

1

eissn

0148-639X

issn

1097-4598

journal_volume

17

pub_type

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