Abstract:
:The voluntary discharge properties and axonal conduction velocity of single motor units were studied in patients with neuromuscular diseases with retained differentiation of the muscle fibers into type 1 and type 2, and in patients with late-onset hereditary distal myopathy in which muscle fibers have only intermediate histochemical properties. In the patients with muscle fiber differentiation, the findings were similar to those in normal subjects; that is, there was a continuum between motor units which fired tonically at low rates and had a low axonal conduction velocity, and motor units which fired phasically at high rates and had a high axonal conduction velocity. In the patients without muscle fiber differentiation, all motor units had intermediate firing properties and a low axonal conduction velocity. It is suggested that in chronic pathologic states, the differentiation of the muscle fiber histochemistry remains only as long as the differentiation of the motor neurons remains.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Borg J,Grimby L,Hannerz Jdoi
10.1002/mus.880020603subject
Has Abstractpub_date
1979-11-01 00:00:00pages
423-30issue
6eissn
0148-639Xissn
1097-4598journal_volume
2pub_type
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