Abstract:
:We describe a consanguineous family that had progressive myopathy with rimmed vacuole (RV) formation and amyloid deposition. Patient 1 is a 71-year-old woman with muscle atrophy in the lumbar girdle and lower extremities. Patient 2 is a 40-year-old man (the son of Patient 1) with fatty changes in the biceps femoris muscles. Muscle biopsies revealed myopathic and neurogenic degeneration with RV, necrotic fibers, and interstitial amyloid deposition. Amyloid deposition was detected only in the muscle tissue.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Kojima Y,Sakai K,Ishida C,Asaka T,Hamaguchi T,Nozaki I,Fukushima K,Tsuchiya A,Kametani F,Yazaki M,Okino S,Yamada Mdoi
10.1002/mus.21373subject
Has Abstractpub_date
2009-09-01 00:00:00pages
472-5issue
3eissn
0148-639Xissn
1097-4598journal_volume
40pub_type
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