Abstract:
:We report an 18-month-old Charcot-Marie-Tooth type 1A (CMT1A) patient who developed a rapid-onset neuropathy, with proximal and distal weakness, and non-uniform nerve conduction studies. The neuropathy responded well to immunomodulation, confirming the coexistence of an inherited and an inflammatory neuropathy. Unexpected clinical and/or electrophysiological manifestations in CMT1A patients should alert clinicians to concomitant inflammatory neuropathy. In addition, this association raises reflections about disease mechanism in CMT1A.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Marques W Jr,Funayama CA,Secchin JB,Lourenço CM,Gouvêa SP,Marques VD,Bastos PG,Barreira AAdoi
10.1002/mus.21753subject
Has Abstractpub_date
2010-10-01 00:00:00pages
598-600issue
4eissn
0148-639Xissn
1097-4598journal_volume
42pub_type
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