Abstract:
:We previously reviewed the presentation, initial clinical course, and electrodiagnostic features of children with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). We now report the long-term follow-up of 12 children with idiopathic CIDP, and compare these to 62 adults with idiopathic CIDP. Children often had more rapidly fluctuating courses than adults. A relapsing course was significantly more common in children than in adults. The recovery of children from each episode of deterioration was usually excellent, and better, on average, than in adults. Ventilatory support was never required for children with slowly evolving illness; only 2 children with a precipitous onset clinically resembling Guillain-Barré syndrome required ventilatory support. Prednisone, plasma exchange, and intravenous immunoglobulin (IVIg) usually were effective in children. Multiple courses of IVIg could be given with continued efficacy. Treatment often could be discontinued in children with relapsing courses. The prognosis for children was excellent. Adults demonstrated a good, but more variable, outcome.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Simmons Z,Wald JJ,Albers JWdoi
10.1002/(sici)1097-4598(199712)20:12<1569::aid-mussubject
Has Abstractpub_date
1997-12-01 00:00:00pages
1569-75issue
12eissn
0148-639Xissn
1097-4598pii
10.1002/(SICI)1097-4598(199712)20:12<1569::AID-MUSjournal_volume
20pub_type
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