Abstract:
:Patients with prior poliomyelitis may experience muscle function deterioration decades after onset of disease. The present study is aimed at describing electromyographic and morphometric evidence of muscular compensation and of on-going muscular instability. Ten subjects 42-62 years of age with onset of polio 25-52 years earlier were studied with macro EMG, single-fiber EMG (SFEMG), muscle strength measurement, and morphometrical analysis of muscle biopsies from the vastus lateralis muscle. SFEMG revealed increased fiber density (FD) and large macro-MUP potentials indicating pronounced reinnervation as compensation to loss of motor neurons. From electrophysiological data of motor unit size, morphometric measures of fiber size, and muscle strength data, the minimal degree of motor neuron loss was estimated to be greater than 70%.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Einarsson G,Grimby G,Stålberg Edoi
10.1002/mus.880130214subject
Has Abstractpub_date
1990-02-01 00:00:00pages
165-71issue
2eissn
0148-639Xissn
1097-4598journal_volume
13pub_type
临床试验,杂志文章相关文献
MUSCLE & NERVE文献大全abstract::Muscle biopsy and computerized tomography indicated that unilateral enlargement of the gastrocnemius muscle in a 12-year-old girl was the result of an infiltrating lipoma. This rare condition may cause diagnostic confusion before EMG and muscle biopsy studies are performed, but it can be readily distinguished from oth...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880010111
更新日期:1978-01-01 00:00:00
abstract::We studied the effect of initiation time of nerve expansion after nerve transection on the induction of ODC activity and Schwann cell proliferation in nerve tissue under Wallerian degeneration. The levels of ODC activity and Schwann cell proliferation decreased as the initiation time of nerve expansion was delayed aft...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199710)20:10<1314::aid-mus
更新日期:1997-10-01 00:00:00
abstract::Our experience and review of the literature reveal that Sjogren's syndrome (SS) is an important, poorly recognized cause of peripheral neuropathy. Several forms of peripheral nerve dysfunction occur in SS including trigeminal sensory neuropathy, mononeuropathy multiplex, distal sensory neuropathy, distal sensorimotor ...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.880130703
更新日期:1990-07-01 00:00:00
abstract:INTRODUCTION:Nebulin is a giant actin-binding protein in the thin filament of the skeletal muscle sarcomere. Studies of nebulin interactions are limited by the size, complexity, and poor solubility of the protein. We divided the nebulin super-repeat region into a super-repeat panel, and studied nebulin/actin interactio...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26350
更新日期:2019-01-01 00:00:00
abstract::The authors reported a large study of 93 children presenting a severe form of progressive muscular dystrophy. The first clinical symptoms were noticed between 3 to 12 years. The atrophy affects, predominantly, the girdle and truncal muscles. The hypertrophy of the calves is almost consistent. The progression of the di...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880060702
更新日期:1983-09-01 00:00:00
abstract:INTRODUCTION:Far-field potentials (FFPs) from muscles other than the abductor digiti minimi (ADM) may interfere with motor unit number estimation (MUNE) from that muscle. METHODS:We identified the origin of each surface motor unit potential (SMUP) during hypothenar MUNE using the multiple point stimulation method in 2...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23746
更新日期:2013-08-01 00:00:00
abstract::Ultrastructural, biochemical, and electrophysiological analyses were done on 12-14-month-old mice deficient for myelin-associated glycoprotein (MAG) to further characterize the neuropathy that develops as they age. Electron microscopy demonstrated normal myelin compaction and axonal degeneration in a large number of m...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.1159
更新日期:2001-10-01 00:00:00
abstract::We investigated whether the modulatory effects of segmental and descending inputs on the soleus H reflex are modified by postural conditions. Fourteen healthy volunteers received a transcranial magnetic stimulus (TMS) or percutaneous electrical stimulation of the posterior tibial nerve (PTN), preceding by 0 to 400 ms ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(200006)23:6<925::aid-mus13
更新日期:2000-06-01 00:00:00
abstract::As caveolin-3 deficiencies may explain persistent hyper-CK-emia, we performed CAV3 gene mutation analysis and immunohistochemistry for caveolin-3 in 31 patients with idiopathic hyper-CK-emia. In 2 of 29 patients who donated blood, variants in the CAV3 gene were detected. Although immunohistochemical analysis strongly ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20593
更新日期:2006-11-01 00:00:00
abstract::Conduction velocity of A delta fibers of the human peripheral nerves was measured by using pain-related somatosensory evoked potentials following CO2 laser stimulation. It was found to be approximately 9 m/s in the forearm as well as in the lower leg. Because conventional conduction study using electric stimulation re...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880141209
更新日期:1991-12-01 00:00:00
abstract:INTRODUCTION:Few data are available to quantify the risks and benefits of microvascular decompression (MVD) in elderly patients with hemifacial spasm. METHODS:Twenty-seven patients >65 years of age and 104 younger patients who underwent MVD for hemifacial spasm (HFS) over a 3-year period were analyzed retrospectively ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23800
更新日期:2013-11-01 00:00:00
abstract::Type-specific antibodies to the polymorphic types of collagen have been used to study their distribution in polymyositis. Dramatic increases were observed in the staining with antibodies to Type III collagen and, to a lesser extent, with antibodies to Types I, IV, and V. The changes in capillary and endomysial basemen...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880030605
更新日期:1980-11-01 00:00:00
abstract::During postnatal development of extensor digitorum longus (EDL) muscle, sodium withdrawal contractures were observed during the first 6 days after birth, and not after this time. In regenerating EDL muscles, zero-Na contractures were demonstrated: (1) 7 days after bupivacaine injection, but not 14 or 90 days after thi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199811)21:11<1530::aid-mus
更新日期:1998-11-01 00:00:00
abstract:INTRODUCTION:In this study, we determined normal levels of dysferlin expression in CD14+ monocytes by flow cytometry (FC) as a screening tool for dysferlinopathies. METHODS:Monocytes from 183 healthy individuals and 29 patients were immunolabeled, run on an FACScalibur flow cytometer, and analyzed by FlowJo software. ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25156
更新日期:2016-12-01 00:00:00
abstract::The origins of impaired finger and hand function were examined in 10 stroke survivors with chronic spastic hemiparesis, with the intent of assessing whether mechanical restraint or altered neurophysiological control mechanisms are responsible for the well-known impairment of finger extension. Simultaneous extension of...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10443
更新日期:2003-09-01 00:00:00
abstract:INTRODUCTION:Conduction block (CB) has been included in the Rajabally criteria for axonal Guillain-Barré syndrome (GBS). Because the nerve roots may be affected early in GBS, detection of proximal CB by the triple stimulation technique (TST) can be useful. METHODS:We describe TST findings in 2 patients who presented w...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24729
更新日期:2015-12-01 00:00:00
abstract:INTRODUCTION:The contribution of cranial and thoracic region electromyography (EMG) to diagnostic criteria for amyotrophic lateral sclerosis (ALS) has not been evaluated. METHODS:Clinical and EMG data from each craniospinal region were retrospectively assessed in 470 patients; 214 had ALS. Changes to diagnostic classi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25062
更新日期:2016-09-01 00:00:00
abstract::The neuromuscular junction (NMJ) is a complex structure that serves to efficiently communicate the electrical impulse from the motor neuron to the skeletal muscle to signal contraction. Over the last 200 years, technological advances in microscopy allowed visualization of the existence of a gap between the motor neuro...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.20440
更新日期:2006-04-01 00:00:00
abstract::The muscle-specific helix-loop-helix (HLH) transcription factors myoD, myogenin, MRF4, and myf-5 are called the muscle regulatory factor family (MRF). Levels of MRFs are strongly regulated by muscle electrical activity and are thought to control downstream genes that are important for muscle phenotype such as the acet...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/1097-4598(200009)23:9<1374::aid-mus8>3.0.c
更新日期:2000-09-01 00:00:00
abstract:INTRODUCTION:Despite the existence of guidelines, painful neuropathy is often inappropriately treated. We sought to determine the effectiveness of a clinical decision support system on guideline-recommended medication use. METHODS:We randomized neurology providers, stratified by subspecialty, to a best practice alert ...
journal_title:Muscle & nerve
pub_type: 杂志文章,随机对照试验
doi:10.1002/mus.26774
更新日期:2020-05-01 00:00:00
abstract:INTRODUCTION:Electrical stimulation of denervated muscle has been shown to minimize atrophy and fibrosis and increase force in animal and human models. However, electrical stimulation after nerve repair is controversial due to questions of efficacy. METHODS:Using a rat model, we investigated the efficacy of short-term...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23726
更新日期:2013-08-01 00:00:00
abstract::We have devised a method of sensory nerve conduction in the interdigital nerves of the foot using the near-nerve needle and signal averaging techniques. In 40 normal controls between the ages of 20 and 59, there was no difficulty in recording sensory compound nerve action potential (CNAP) in the various interdigital n...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880070306
更新日期:1984-03-01 00:00:00
abstract:INTRODUCTION:Venous access for therapeutic plasma exchange (TPE) in myasthenia gravis (MG) can be achieved by central venous catheters (CVC) or peripheral veins (PV), and the preferred method varies among providers. We evaluated our institutional experience with TPE venous access method and complications. METHODS:We r...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23508
更新日期:2013-02-01 00:00:00
abstract:INTRODUCTION:Mutations in gap junction protein beta 1 (GJB1) on the X chromosome represent one of the most common causes of hereditary neuropathy. We assessed manifestations associated with a rare 3' untranslated region mutation (UTR) of GJB1 in a large family with X-linked Charcot-Marie-Tooth disease (CMTX). METHODS:...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26037
更新日期:2018-05-01 00:00:00
abstract::The lack of effective therapy for many of the chronic neuromuscular diseases such as amyotrophic lateral sclerosis, hereditary motor sensory neuropathy (Charcot-Marie-Tooth disease), spinocerebellar degenerations and idiopathic polyneuropathy has led to a search for substances that may stimulate peripheral nerve regen...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.880130910
更新日期:1990-09-01 00:00:00
abstract::The axonal distribution of voltage-dependent Na+ channels was determined during inflammatory demyelinating disease of the peripheral nervous system. Experimental allergic neuritis was induced in Lewis rats by active immunization. In diseased spinal roots Na+ channel immunofluorescence at many nodes of Ranvier changed ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199808)21:8<1019::aid-mus6
更新日期:1998-08-01 00:00:00
abstract::Familial amyotrophic lateral sclerosis (ALS) with the autosomal-recessively inherited D90A CuZn-superoxide dismutase (CuZn-SOD) mutation is characterized by a stereotypic slowly progressive, distinctive phenotype and very slow central motor conduction. To determine the basis of this slowing, we assessed corticomotoneu...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/1097-4598(200101)24:1<89::aid-mus10>3.0.co
更新日期:2001-01-01 00:00:00
abstract::L-carnitine stimulated CO2 production from 1-14C pyruvate in mitochondria from human skeletal muscle nearly twofold. A comparable increase in the pyruvate dehydrogenase complex (PDHC) activity was seen. Moreover, in the presence of L-carnitine and at pyruvate concentration greater than 0.25 mM, this effect was associa...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880110708
更新日期:1988-07-01 00:00:00
abstract::Normative values of muscle fiber conduction velocity depend on the conditions in which conduction velocity is measured due to the velocity recovery function (VRF) of muscle fibers. In this study the VRF of the compound muscle action potential (CMAP) was assessed following doublet and triplet stimulation in order to in...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20801
更新日期:2007-08-01 00:00:00
abstract::McArdle disease is an autosomal recessive muscle glycogenosis. In the typical clinical presentation, only exercise-related symptoms are noted. Nevertheless, permanent weakness may occur, usually late in life. In this study we report on the clinical and genetic features of fixed muscle weakness in McArdle disease. Amon...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21351
更新日期:2009-09-01 00:00:00