Abstract:
INTRODUCTION:The contribution of cranial and thoracic region electromyography (EMG) to diagnostic criteria for amyotrophic lateral sclerosis (ALS) has not been evaluated. METHODS:Clinical and EMG data from each craniospinal region were retrospectively assessed in 470 patients; 214 had ALS. Changes to diagnostic classification in Awaji-Shima and revised El Escorial criteria after withdrawal of cranial/thoracic EMG data were ascertained. RESULTS:Sensitivity for lower motor neuron involvement in ALS was highest in the cervical/lumbar regions; specificity was highest in cranial/thoracic regions. Cranial EMG contributed to definite/probable Awaji-Shima categorization in 1.4% of patients. Thoracic EMG made no contribution. For revised El Escorial criteria, cranial and thoracic data reclassified 1% and 5% of patients, respectively. CONCLUSION:Cranial EMG data make small contributions to both criteria, whereas thoracic data contribute only to the revised El Escorial criteria. However, cranial and thoracic region abnormalities are specific in ALS. Consideration should be given to allowing greater diagnostic contribution from thoracic EMG. Muscle Nerve 54: 378-385, 2016.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Jenkins TM,Alix JJ,Kandler RH,Shaw PJ,McDermott CJdoi
10.1002/mus.25062subject
Has Abstractpub_date
2016-09-01 00:00:00pages
378-85issue
3eissn
0148-639Xissn
1097-4598journal_volume
54pub_type
杂志文章相关文献
MUSCLE & NERVE文献大全abstract::Thyrotropin-releasing hormone (TRH), present in high concentrations in the mammalian spinal cord, exerts excitatory effects on the alpha-motorneuron (AMN) via axodendritic contacts. We used the neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) to deplete TRH from the ventral horn of the spinal cord of adult rats to determi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880100504
更新日期:1987-06-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to investigate in vivo median nerve longitudinal mobility in different segments of the carpal tunnel associated with active finger motion in carpal tunnel syndrome (CTS) patients in a comparison with healthy controls. METHODS:Eleven healthy volunteers and 11 CTS patients part...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.27017
更新日期:2020-10-01 00:00:00
abstract::Calpains are Ca2+ -dependent cytosolic cysteine proteases that participate in the pathology of Duchenne muscular dystrophy (DMD). Utrophin is a functional homolog of dystrophin that partially compensates for dystrophin deficiency in myofibers of mdx mice. In this study, we investigated the susceptibility of utrophin t...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20549
更新日期:2006-06-01 00:00:00
abstract:INTRODUCTION:We sought to translate, cross-culturally adapt, and evaluate the internal consistency and validity of the Chinese version of the 15-Item Myasthenia Gravis Quality of Life (MG-QOL15). METHODS:Translation and cross-cultural adaptation of the MG-QOL15 were performed. We used Cronbach's α to test internal con...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26313
更新日期:2019-01-01 00:00:00
abstract::The ideal electrodiagnostic procedure to assess possible plantar neuropathies continues to elude investigators. Motor studies are rarely abnormal, pure sensory studies may be difficult to obtain, needle electromyography can demonstrate membrane instability in normal feet. Mixed nerve plantar studies may be more diagno...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880140710
更新日期:1991-07-01 00:00:00
abstract::If anti-GM1 antibody plays a role in the axonal damage in Guillain-Barré syndrome, the common entrapment sites may be preferentially involved with evidence of axonal dysfunction. To assess this hypothesis, we studied nerve conduction across the cubital tunnel in 44 patients. Abnormal amplitude reduction of compound mu...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-4598(199907)22:7<840::aid-mus5>
更新日期:1999-07-01 00:00:00
abstract::New developments in the rapid diagnosis and treatment of boys with Duchenne muscular dystrophy (DMD) have led to growing enthusiasm for instituting DMD newborn screening (NBS) in the United States. Our group has been interested in developing clinical guidance to be implemented consistently in specialty care clinics ch...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25185
更新日期:2016-08-01 00:00:00
abstract::Median neuropathies proximal to the wrist are uncommon and usually result from penetrating injuries, fracture dislocation of the distal humerus, or compression by fibrous bands. A 66-year-old man suffered a comminuted fracture of the proximal humerus after a fall. Electrodiagnostic studies revealed a severe proximal m...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(200003)23:3<426::aid-mus15
更新日期:2000-03-01 00:00:00
abstract:INTRODUCTION:We investigated the viscoelastic stress relaxation response before and after a 10-week hamstrings static stretch program. METHODS:The maximal range of motion (ROMmax ) and maximal torque (Torquemax ) were assessed before and after a 10-week stretching program. Six 30-s static stretches at a predetermined ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24593
更新日期:2015-05-01 00:00:00
abstract::Although the effect of low temperature on the peripheral nervous system has been systematically studied, the effect of high temperature has not. We investigated the effect of elevating limb temperature from 32 degrees C to 42 degrees C by performing sequential motor studies, antidromic sensory studies, and 3-Hz repeti...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199704)20:4<431::aid-mus5>
更新日期:1997-04-01 00:00:00
abstract::Recent years have seen steady progress in the identification of genetic muscle diseases as well as efforts to develop treatment for these diseases. Consequently, sensitive and objective new methods are required to identify and monitor muscle pathology. Magnetic resonance imaging offers multiple potential biomarkers of...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.26497
更新日期:2019-10-01 00:00:00
abstract:INTRODUCTION:Intensive care unit (ICU) patients often develop weakness. Rehabilitation is initiated early to prevent physical deterioration, but knowledge of optimal training schedules is lacking. A reliable method to assess muscle activity during exercise is needed. In this study we explored the feasibility of electri...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26330
更新日期:2018-11-01 00:00:00
abstract:INTRODUCTION:GNE myopathy is a rare recessive myopathy caused by mutations in the GNE gene. It is mainly a distal myopathy with relative sparing of the quadriceps muscle. METHODS:Patients with distal myopathies from Kuwait were examined and tested for the Middle Eastern GNE gene founder mutation, p.M743T. Patients wer...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26337
更新日期:2018-11-01 00:00:00
abstract:INTRODUCTION:Muscle fiber denervation increases with age, yet studies at the tissue level are sparse due to the challenging nature of establishing the relative role of regeneration and denervation. METHODS:Muscle biopsies were obtained from the vastus lateralis of 70 healthy men (aged 72 ± 6 years; range, 65-94). Mess...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26638
更新日期:2019-10-01 00:00:00
abstract::Electrodiagnostic evaluation of patients with suspected polyneuropathy is useful for detecting and documenting peripheral abnormalities, identifying the predominant pathophysiology, and determining the prognosis for certain disorders. The electrodiagnostic classification of polyneuropathy is associated with morphologi...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.880131002
更新日期:1990-10-01 00:00:00
abstract:BACKGROUND:Our pilot study tested the feasibility and performance of an eye-controlled power wheelchair for amyotrophic lateral sclerosis (ALS) patients. METHODS:In this prospective pilot study, participants drove the wheelchair three times around an indoor course. We assessed the time to complete the course; starting...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26655
更新日期:2019-11-01 00:00:00
abstract:INTRODUCTION:The etiology of neuropathy was idiopathic in 20%-30% of patients despite thorough investigation, based on results from the 1980s and 1990s. Since then, new etiologies have been recognized, and skin biopsy has been used to confirm small-fiber neuropathy. METHODS:The authors reviewed the charts of 373 patie...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24969
更新日期:2016-06-01 00:00:00
abstract::Mycophenolate mofetil 1.5 g daily (30 mg/kg body weight) was given to a patient with ankylosing spondylitis, ulcerative colitis, and severe refractory polymyositis after conventional treatment regimes had failed. No severe side effects occurred. Considerable improvement of clinical symptoms and electromyographic findi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10026
更新日期:2002-02-01 00:00:00
abstract:INTRODUCTION:Two previously reported Norwegian patients with painful muscle cramps and giant myotonic discharges were genotyped and compared with those of members of 21 families harboring the same mutation. METHODS:Using primers specific for SCN4A and CLCN1, the DNA of the Norwegian family members was amplified and bi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24672
更新日期:2015-10-01 00:00:00
abstract::Masseter (MR) and blink reflexes (BL) were investigated in 51 patients with internuclear ophthalmoplegia (INO) due to multiple sclerosis (28) and lacunar infarction (23). The MR was abnormal in 20 of 23 cases with bilateral INO and in 21 of 28 with unilateral INO. The R1 component of the BL (BL-R1) was abnormal in 7 o...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880140406
更新日期:1991-04-01 00:00:00
abstract::A 53-year-old man developed multifocal radicular pain. The diagnosis of Lyme neuroborreliosis was delayed until bifacial paresis and right lower abdominal wall weakness developed, prompting further evaluation. Cerebrospinal fluid (CSF) examination showed aseptic meningitis. Antibodies directed against Borrelia burgdor...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880161118
更新日期:1993-11-01 00:00:00
abstract::The fastest median and ulnar velocities derived by recording motor and mixed nerve action potentials, F waves, H-reflexes, and somatosensory evoked potentials (SEPs) were compared. H-reflex recording was facilitated by employing selective group Ia excitation during voluntary muscular contraction. Mixed nerve, SEP, and...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880070807
更新日期:1984-10-01 00:00:00
abstract::The goal of this study was to estimate the accuracy of concentric-needle single-fiber electromyography (CN-SFEMG) for the diagnosis of myasthenia gravis (MG). A consecutive series of patients referred for CN-SFEMG was evaluated by an investigator blinded to the results of CN-SFEMG in order to determine the presence or...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20568
更新日期:2006-08-01 00:00:00
abstract:INTRODUCTION:Paraneoplastic lower motor neuronopathies have been reported rarely with Hodgkin lymphoma. METHODS:We report a case of rapidly progressive motor neuronopathy preceding the diagnosis of Hodgkin lymphoma. RESULTS:A 31-year-old woman developed subacute rapidly progressive quadriparesis. Electrodiagnostic st...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23464
更新日期:2012-11-01 00:00:00
abstract::In an attempt to determine the relative importance of the nerve cell body and of the axon in initiating and controlling axonal regeneration, nerve cell bodies were irradiated and the ability of the distal axon to sprout was examined. Mice were subjected to either 25 or 50 Gray (Gy) of x-irradiation localized to the lu...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880110513
更新日期:1988-05-01 00:00:00
abstract::Epstein-Barr virus infection can affect both the central and peripheral nervous system. In some patients this occurs concurrently. Two patients are presented with encephalopathy and acute quadriparesis with diminished reflexes. Positive serology for Epstein-Barr virus was found in both patients. Both patients had a ce...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(SICI)1097-4598(199608)19:8<1037::AID-MUS1
更新日期:1996-08-01 00:00:00
abstract::At least 50 disease-causing mutations in the skeletal muscle voltage-gated chloride channel gene (CLCN1), almost all of which originate from Caucasian families, have been identified. We investigated a Japanese family with Thomsen's myotonia congenita that included 16 affected individuals (8 men and 8 women) through fi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/1097-4598(200103)24:3<357::aid-mus1006>3.0
更新日期:2001-03-01 00:00:00
abstract:INTRODUCTION:Nerve enlargement (NE) is described in inflammatory and inherited neuropathies. It is commonly multifocal and moderate in the former and homogeneous and generalized in the latter. We describe 4 cases of massive NE in inflammatory neuropathies. METHODS:Patients presented with symptoms of polyneuropathy tha...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25272
更新日期:2017-02-01 00:00:00
abstract::Both high and low body mass index (BMI) have been reported as risk factors for ulnar neuropathy at the elbow (UNE), and a high BMI as a risk factor for carpal tunnel syndrome (CTS). To determine whether the extremes of BMI are risk factors for UNE or CTS, and whether BMI affects calculation of median and ulnar motor n...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20345
更新日期:2005-09-01 00:00:00
abstract:INTRODUCTION:In preparation for clinical trials we examine the validity, reliability, and patient understanding of the Myotonic Dystrophy Health Index (MDHI). METHODS:Initially we partnered with 278 myotonic dystrophy type-1 (DM1) patients and identified the most relevant questions for the MDHI. Next, we used factor a...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24097
更新日期:2014-06-01 00:00:00