Midbrain vs. pontine medial longitudinal fasciculus lesions: the utilization of masseter and blink reflexes.

Abstract:

:Masseter (MR) and blink reflexes (BL) were investigated in 51 patients with internuclear ophthalmoplegia (INO) due to multiple sclerosis (28) and lacunar infarction (23). The MR was abnormal in 20 of 23 cases with bilateral INO and in 21 of 28 with unilateral INO. The R1 component of the BL (BL-R1) was abnormal in 7 of 23 patients with bilateral INO and 10 of 28 with unilateral INO. Combined MR and BL-R1 changes occurred in 8 of 28 cases with unilateral INO and 7 of 23 with bilateral INO. The findings provide evidence for a rostral/caudal localization of lesions within the medial longitudinal fasciculus causing INO on the basis of MR and BL-R1 abnormalities. An abnormality limited to MR suggests a midbrain location in 58.8% of patients while abnormal BL-R1 with or without an associated MR change suggests a rostral pontine location in 35.3%.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Hopf HC,Thömke F,Gutmann L

doi

10.1002/mus.880140406

subject

Has Abstract

pub_date

1991-04-01 00:00:00

pages

326-30

issue

4

eissn

0148-639X

issn

1097-4598

journal_volume

14

pub_type

杂志文章
  • Posture-related changes of soleus H-reflex excitability.

    abstract::We investigated whether the modulatory effects of segmental and descending inputs on the soleus H reflex are modified by postural conditions. Fourteen healthy volunteers received a transcranial magnetic stimulus (TMS) or percutaneous electrical stimulation of the posterior tibial nerve (PTN), preceding by 0 to 400 ms ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(200006)23:6<925::aid-mus13

    authors: Goulart F,Valls-Solé J,Alvarez R

    更新日期:2000-06-01 00:00:00

  • Neuromuscular complications of connective tissue diseases.

    abstract::The connective tissue diseases, such as rheumatoid arthritis, Sjögren's syndrome, systemic lupus erythematosus, systemic sclerosis, and vasculitis, may cause various disorders of the peripheral nervous system. In this review, the clinical effects of the connective tissues diseases on nerve and muscle are examined with...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审

    doi:10.1002/1097-4598(200102)24:2<154::aid-mus20>3.0.c

    authors: Rosenbaum R

    更新日期:2001-02-01 00:00:00

  • Axonal involvement at the common entrapment sites in Guillain-Barré syndrome with IgG anti-GM1 antibody.

    abstract::If anti-GM1 antibody plays a role in the axonal damage in Guillain-Barré syndrome, the common entrapment sites may be preferentially involved with evidence of axonal dysfunction. To assess this hypothesis, we studied nerve conduction across the cubital tunnel in 44 patients. Abnormal amplitude reduction of compound mu...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章

    doi:10.1002/(sici)1097-4598(199907)22:7<840::aid-mus5>

    authors: Kuwabara S,Mori M,Ogawara K,Mizobuchi K,Hattori T,Koga M,Yuki N

    更新日期:1999-07-01 00:00:00

  • Prolonged erythropoietin treatment does not impact gene expression in human skeletal muscle.

    abstract:INTRODUCTION:We tested for the presence of erythropoietin receptor (Epo-R) in human skeletal muscle and alterations in gene expression after prolonged use of an erythropoiesis-stimulating agent (ESA). METHODS:Nine healthy men were treated with ESA for 10 weeks (darbepoietin alfa). Muscle biopsies were collected before...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.24355

    authors: Christensen B,Nellemann B,Thorsen K,Nielsen MM,Pedersen SB,Ornstrup MJ,JØrgensen JO,Jessen N

    更新日期:2015-04-01 00:00:00

  • Dysferlin quantification in monocytes for rapid screening for dysferlinopathies.

    abstract:INTRODUCTION:In this study, we determined normal levels of dysferlin expression in CD14+ monocytes by flow cytometry (FC) as a screening tool for dysferlinopathies. METHODS:Monocytes from 183 healthy individuals and 29 patients were immunolabeled, run on an FACScalibur flow cytometer, and analyzed by FlowJo software. ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25156

    authors: Sánchez-Chapul L,Ángel-Muñoz MD,Ruano-Calderón L,Luna-Angulo A,Coral-Vázquez R,Hernández-Hernández Ó,Magaña JJ,León-Hernández SR,Escobar-Cedillo RE,Vargas S

    更新日期:2016-12-01 00:00:00

  • Ultrasonography of sciatic nerve endometriosis.

    abstract:INTRODUCTION:We describe the ultrasonographic findings of sciatic nerve endometriosis. METHODS:Two premenopausal women with catamenial sciatica symptoms were examined, the first without a history of endometriosis, the second with previously confirmed endometriosis of the ovary. Ultrasonography, extending from the scia...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25152

    authors: Arányi Z,Polyák I,Tóth N,Vermes G,Göcsei Z

    更新日期:2016-09-01 00:00:00

  • The dropped head syndrome with chronic inflammatory demyelinating polyneuropathy.

    abstract::The dropped head syndrome occurs in a variety of neuromuscular disorders. We present a woman with chronic inflammatory demyelinating polyneuropathy who developed this syndrome, likely reflecting severe demyelination of nerves to cervical paraspinal muscles. ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880170717

    authors: Hoffman D,Gutmann L

    更新日期:1994-07-01 00:00:00

  • Multiple forms of anti-acetylcholine receptor antibody in myasthenia gravis.

    abstract::Sera of patients with myasthenia gravis (MG) contain anti-acetylcholine receptor (AChR) IgG antibodies (Ab) which have different antigenic specificities. Three Ab types were detected: (1) MG-I, which forms immune complexes with AChR; (2) MG-C, which decreases binding of AChR to concanavalin A; and MG-B, which blocks a...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880040105

    authors: Mittag T,Massa T,Kornfeld P,Papatestas A,Bender A,Genkins G

    更新日期:1981-01-01 00:00:00

  • Response to therapy in demyelinating motor neuropathy.

    abstract::We reviewed results of immunotherapy in patients with demyelinating motor neuropathy (DMN), and found that patients over 50 years of age at onset responded poorly, and younger patients responded variably to intervention. We suggest that patients with DMN be given a guarded prognosis, particularly if >50 years of age a...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199812)21:12<1769::aid-mus

    authors: Markson L,Janzen D,Bril V

    更新日期:1998-12-01 00:00:00

  • Neuroimaging of classic neuralgic amyotrophy.

    abstract:INTRODUCTION:Neuralgic amyotrophy (NA) often imposes diagnostic problems. Recently, MRI and high-resolution ultrasound (HRUS) have proven useful in diagnosing peripheral nerve disorders. METHODS:We performed a chart and imaging review of patients who were examined using neuroimaging and who were referred because of cl...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25147

    authors: Lieba-Samal D,Jengojan S,Kasprian G,Wöber C,Bodner G

    更新日期:2016-12-01 00:00:00

  • Early changes of muscle insulin-like growth factor-1 and myostatin gene expression in gastric cancer patients.

    abstract:INTRODUCTION:Cachexia increases morbidity and mortality of cancer patients. The progressive loss of muscle mass negatively affects physical function and quality of life. We previously showed reduced muscle insulin-like growth factor-1 (IGF-1) expression and enhanced myostatin signaling in tumor-bearing animals. This st...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23798

    authors: Bonetto A,Penna F,Aversa Z,Mercantini P,Baccino FM,Costelli P,Ziparo V,Lucia S,Rossi Fanelli F,Muscaritoli M

    更新日期:2013-09-01 00:00:00

  • Electrophysiologic findings and grip strength after nerve injuries in the rat forelimb.

    abstract::We developed electrophysiologic methods for testing the three major forelimb nerves as a tool to evaluate motor and sensory recovery in rats. Median, ulnar, or radial nerves were transected and repaired in Sprague-Dawley rats. Compound muscle action potentials (CMAPs) and somatosensory evoked potentials (SSEPs) were r...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20971

    authors: Wang H,Sorenson EJ,Spinner RJ,Windebank AJ

    更新日期:2008-10-01 00:00:00

  • Fiber-type dependence of stretch-induced force enhancement in rat skeletal muscle.

    abstract::When an active muscle is stretched, the force increases due to strain of contractile and noncontractile proteins. We examined this force enhancement in rat extensor digitorum longus (EDL) and soleus muscles, which differ in their composition of these proteins, and their susceptibility to damage. Small stretches were a...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21744

    authors: Ramsey KA,Bakker AJ,Pinniger GJ

    更新日期:2010-11-01 00:00:00

  • Nerve ultrasound reliability of upper limbs: Effects of examiner training.

    abstract:INTRODUCTION:Duration of training to reliably measure nerve cross-sectional area with ultrasound is unknown. METHODS:A retrospective review was performed of ultrasound data, acquired and recorded by 2 examiners-an expert and either a trainee with 2 months (novice) or a trainee with 12 months (experienced) of experienc...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25980

    authors: Garcia-Santibanez R,Dietz AR,Bucelli RC,Zaidman CM

    更新日期:2018-02-01 00:00:00

  • B-cell-activating factor is elevated in serum of patients with myasthenia gravis.

    abstract:INTRODUCTION:Myasthenia gravis (MG) is a B-cell-mediated autoimmune disease. B-cell-activating factor (BAFF) is a major factor in B-cell development and activation. In this study we investigated serum BAFF levels in MG patients. METHODS:We compared the serum BAFF levels of 20 MG patients with gender-matched healthy co...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25162

    authors: Kang SY,Kang CH,Lee KH

    更新日期:2016-12-01 00:00:00

  • Anatomic variation of the innervation of the flexor digitorum profundus muscle and its clinical implications.

    abstract::In anterior interosseous nerve syndrome and ulnar neuropathy, paralysis or weakness of the flexor digitorum profundus (FDP) muscles has been shown to vary according to the degree of involvement of the median and ulnar nerves, respectively. We traced these nerves in 50 cadaveric specimens in which each FDP was complete...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21281

    authors: Oh CS,Won HS,Lee KS,Chung IH,Kim SM

    更新日期:2009-04-01 00:00:00

  • GNE myopathy in the bedouin population of Kuwait: Genetics, prevalence, and clinical description.

    abstract:INTRODUCTION:GNE myopathy is a rare recessive myopathy caused by mutations in the GNE gene. It is mainly a distal myopathy with relative sparing of the quadriceps muscle. METHODS:Patients with distal myopathies from Kuwait were examined and tested for the Middle Eastern GNE gene founder mutation, p.M743T. Patients wer...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.26337

    authors: Alrohaif H,Pogoryelova O,Al-Ajmi A,Aljeryan LA,Alrashidi NH,Alefasi SA,Urtizberea A,Lochmüller H,Bastaki L

    更新日期:2018-11-01 00:00:00

  • Repetitive nerve stimulation of facial muscles in MuSK antibody-positive myasthenia gravis.

    abstract::To better define electrophysiological abnormalities in myasthenia gravis (MG) patients with muscle-specific tyrosine kinase (MuSK) antibodies (Ab), we compared electrophysiological features of 14 MuSK Ab-positive, 73 acetylcholine receptor antibody (AChR Ab)-positive, and 22 MuSK and AChR Ab-negative (seronegative) pa...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20498

    authors: Oh SJ,Hatanaka Y,Hemmi S,Young AM,Scheufele ML,Nations SP,Lu L,Claussen GC,Wolfe GI

    更新日期:2006-04-01 00:00:00

  • Association between wrist ratio and carpal tunnel syndrome: Effect modification by body mass index.

    abstract:INTRODUCTION:Previous studies have reported higher wrist ratios (WR) related to carpal tunnel syndrome (CTS) but have not assessed effect modification by obesity and may have inadequately controlled for confounders. METHODS:Baseline data of a multicenter prospective cohort study were analyzed. CTS was defined by nerve...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,多中心研究

    doi:10.1002/mus.25692

    authors: Thiese MS,Merryweather A,Koric A,Ott U,Wood EM,Kapellusch J,Foster J,Garg A,Deckow-Schaefer G,Tomich S,Kendall R,Drury DL,Wertsch J,Hegmann KT,Wistah Study Team.

    更新日期:2017-12-01 00:00:00

  • Detection of hereditary neuropathy with liability to pressure palsies among patients with acute painless mononeuropathy or plexopathy.

    abstract::Hereditary neuropathy with liability to pressure palsies (HNPP) is an autosomal dominant disorder characterized by recurrent mononeuropathies or brachial plexopathies, commonly associated with a chromosome 17p11.2-12 deletion encompassing the peripheral myelin protein-22 (PMP22) gene. We tried to identify criteria dis...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199812)21:12<1686::aid-mus

    authors: Pareyson D,Solari A,Taroni F,Botti S,Fallica E,Scaioli V,Ciano C,Sghirlanzoni A

    更新日期:1998-12-01 00:00:00

  • Time and frequency domain analysis of acoustic signals from a human muscle.

    abstract::We wished to determine whether evoked force output from a human muscle could be inferred from the amplitude and the frequency of evoked muscular sounds. Sounds from adductor pollicis were recorded with a microphone and compared to evoked force changes produced by varying the intensity of nerve stimulation or of volunt...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(199708)20:8<991::aid-mus9>

    authors: Chen D,Durand LG,Bellemare F

    更新日期:1997-08-01 00:00:00

  • Marked increase in CD44-highly positive cells in hyperplastic thymuses from patients with Myasthenia gravis.

    abstract::To investigate the role of the thymus in the pathogenesis of myasthenia gravis (MG), immunohistochemical expression of CD44, CD45R0, B7-1, and IL-2 was studied in: (1) hyperplastic thymuses of patients with MG whose symptoms markedly improved after thymectomy, (2) remnant thymuses of patients with MG whose symptoms di...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4598(200004)23:4<507::aid-mus8>

    authors: Utsugisawa K,Nagane Y,Tohgi H

    更新日期:2000-04-01 00:00:00

  • Quantitative laryngeal electromyography parameters may correlate with improved outcomes following botulinum toxin injection for spasmodic dysphonia.

    abstract:BACKGROUND:Despite use of qualitative laryngeal electromyography (LEMG) guided botulinum toxin A (BoNT-A) injection for treatment of adductor spasmodic dysphonia (AdSD), unsatisfactory injections and complete "misses" remain problematic. We aimed to determine if the quantitative LEMG measure of number of small segments...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.27161

    authors: Dwyer CD,Leclerc AA,Nandedkar SD,Young VN,Rosen CA

    更新日期:2020-12-31 00:00:00

  • Bone density and alendronate effects in Duchenne muscular dystrophy patients.

    abstract:INTRODUCTION:Patients with DMD have low bone mineral density (BMD) and are at high risk for fractures. We examined changes in BMD and the effects of alendronate in DMD patients treated at our institution in the last decade. METHODS:Retrospective cohort study of 39 DMD patients. RESULTS:Patients had screening dual ene...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.23948

    authors: Houston C,Mathews K,Shibli-Rahhal A

    更新日期:2014-04-01 00:00:00

  • Chronic peripheral nerve compression disrupts paranodal axoglial junctions.

    abstract:INTRODUCTION:Peripheral nerves are often exposed to mechanical stress leading to compression neuropathies. The pathophysiology underlying nerve dysfunction by chronic compression is largely unknown. METHODS:We analyzed molecular organization and fine structures at and near nodes of Ranvier in a compression neuropathy ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.25273

    authors: Otani Y,Yermakov LM,Dupree JL,Susuki K

    更新日期:2017-04-01 00:00:00

  • Comparing the force- and excursion- frequency relationships in human skeletal muscle.

    abstract::We examined the influence of varying stimulation frequency on muscle output during isometric and dynamic contractions. Our findings demonstrate that the predictability of the force- and excursion-frequency relationships is extremely strong across stimulation intensities. There were no differences in the frequency whic...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.21161

    authors: Gregory CM,Bickel CS,Sharma N,Dixon WE

    更新日期:2008-12-01 00:00:00

  • Physiogenomic association of statin-related myalgia to serotonin receptors.

    abstract::We employed physiogenomic analyses to investigate the relationship between myalgia and selected polymorphisms in serotonergic genes, based on their involvement with pain perception and transduction of nociceptive stimuli. We screened 195 hypercholesterolemic, statin-treated patients, all of whom received either atorva...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20871

    authors: Ruaño G,Thompson PD,Windemuth A,Seip RL,Dande A,Sorokin A,Kocherla M,Smith A,Holford TR,Wu AH

    更新日期:2007-09-01 00:00:00

  • Facing the diagnostic challenge: Nerve ultrasound in diabetic patients with neuropathic symptoms.

    abstract:INTRODUCTION:We describe the nerve ultrasound findings in patients with type II diabetes mellitus who have neuropathic symptoms and signs. METHODS:Fifty-five healthy controls and 44 diabetic patients underwent clinical, sonographic, and electrophysiological evaluation. Patients were studied at a mean of 14.3 years aft...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.24981

    authors: Pitarokoili K,Kerasnoudis A,Behrendt V,Labedi A,Ayzenberg I,Gold R,Yoon MS

    更新日期:2016-06-01 00:00:00

  • Iron load and redox stress in skeletal muscle of aged rats.

    abstract::Loss of skeletal muscle mass (sarcopenia) is a major contributor to disability in old age. We used two-dimensional gel electrophoresis and mass spectrometry to screen for changes in proteins, and cDNA profiling to assess transcriptional regulations in the gastrocnemius muscle of adult (4 months) and aged (30 months) m...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.20808

    authors: Altun M,Edström E,Spooner E,Flores-Moralez A,Bergman E,Tollet-Egnell P,Norstedt G,Kessler BM,Ulfhake B

    更新日期:2007-08-01 00:00:00

  • Severe childhood muscular dystrophy affecting both sexes and frequent in Tunisia.

    abstract::The authors reported a large study of 93 children presenting a severe form of progressive muscular dystrophy. The first clinical symptoms were noticed between 3 to 12 years. The atrophy affects, predominantly, the girdle and truncal muscles. The hypertrophy of the calves is almost consistent. The progression of the di...

    journal_title:Muscle & nerve

    pub_type: 杂志文章

    doi:10.1002/mus.880060702

    authors: Ben Hamida M,Fardeau M,Attia N

    更新日期:1983-09-01 00:00:00