Axonal involvement at the common entrapment sites in Guillain-Barré syndrome with IgG anti-GM1 antibody.

abstract：INTRODUCTION:Breast cancer is exceptionally associated with anti-collapsin response mediator protein 5 (anti-CRMP5) antibody or demyelinating neuropathy. This paraneoplastic antibody is itself not associated with demyelinating neuropathy. METHODS:Herein we describe a patient with a predominantly sensory ataxic demyeli...

journal_title：Muscle & nerve

authors： Samarasekera S,Rajabally YA

更新日期：2011-05-01 00:00:00

abstract：:The goal of this study was to estimate the accuracy of concentric-needle single-fiber electromyography (CN-SFEMG) for the diagnosis of myasthenia gravis (MG). A consecutive series of patients referred for CN-SFEMG was evaluated by an investigator blinded to the results of CN-SFEMG in order to determine the presence or...

journal_title：Muscle & nerve

authors： Benatar M,Hammad M,Doss-Riney H

更新日期：2006-08-01 00:00:00

abstract：:Immunocytochemical analysis of muscle specimens from 5 patients with acute quadriplegic myopathy indictes that depletion of either fast or slow myosin occurs in this disorder. The initial lesion consists of focal myosin loss in nonatrophic fibers. Other structural proteins (actin, titin, nebulin) are spared or affecte...

journal_title：Muscle & nerve

authors： Showalter CJ,Engel AG

更新日期：1997-03-01 00:00:00

abstract：:The protein compositions of subcellular fractions of muscle obtained from 17 Duchenne dystrophy patients, 15 disease controls (10 different primary myopathies, 5 spinal muscular atrophy patients), and 10 normals were examined by polyacrylamide gel electrophoresis. The gels were stained with Coomassie Brilliant Blue an...

journal_title：Muscle & nerve

authors： Niebroj-Dobosz I,Kornguth S,Schutta H,Siegel FL,Hausmanowa-Petrusewicz I

更新日期：1989-04-01 00:00:00

abstract：:The connective tissue diseases, such as rheumatoid arthritis, Sjögren's syndrome, systemic lupus erythematosus, systemic sclerosis, and vasculitis, may cause various disorders of the peripheral nervous system. In this review, the clinical effects of the connective tissues diseases on nerve and muscle are examined with...

journal_title：Muscle & nerve

authors： Rosenbaum R

更新日期：2001-02-01 00:00:00

abstract：:The purpose of this study was to investigate whether the previously demonstrated heterogeneity of myosin heavy chain (MHC) in type 2B fibers of the superficial portion of the lateral gastrocnemius (SLG) muscle of the rat may be due to presence of type 2D/X fibers. Immunohistochemical identification of MHC heterogeneit...

journal_title：Muscle & nerve

authors： Sawchak JA,Leung B,Shafiq SA

更新日期：1992-12-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal disease with limited treatment options. Controlled studies are a necessary part of Phase II and Phase III assessments of proposed therapies. Due to the relatively small number of patients with ALS, several study designs have been proposed to improve the efficiency of Phas...

journal_title：Muscle & nerve

authors： Simmons Z

更新日期：2009-06-01 00:00:00

abstract：:A large Swedish family with members affected by progressive external ophthalmoplegia with hypogonadism were followed-up and reviewed. Hypogonadism included delayed sexual maturation, primary amenorrhea, early menopause, and testicular atrophy. Cataracts, cerebellar ataxia, neuropathy, hypoacusia, pes cavus, tremor, pa...

journal_title：Muscle & nerve

authors： Melberg A,Arnell H,Dahl N,Stålberg E,Raininko R,Oldfors A,Bakall B,Lundberg PO,Holme E

更新日期：1996-12-01 00:00:00

abstract：:We investigated factors affecting maximal voluntary torque and the assessment of the level of voluntary drive in the elbow flexor muscles. First, the effective compliance of the system was tested by using single, paired, and trains of four stimuli to measure voluntary activation. At high voluntary torques the response...

journal_title：Muscle & nerve

authors： Allen GM,McKenzie DK,Gandevia SC

更新日期：1998-03-01 00:00:00

abstract：INTRODUCTION:The ability to individualize recommendations or expectations of disease progression based on a patient's unique characteristics has merit for use in sporadic inclusion body myositis (sIBM). METHODS:Fifty-five subjects with sIBM completed a battery of strength and functional outcomes at 2 study visits. The...

journal_title：Muscle & nerve

authors： Alfano LN,Yin H,Dvorchik I,Maus EG,Flanigan KM,Mendell JR,Lowes LP

更新日期：2017-04-01 00:00:00

abstract：:Force fluctuations in leg muscles increase after bedrest, perhaps due to modulation of the neural strategy that is specific to a muscle or common to agonist muscles. The purpose of this study was to examine the modulation of muscle activity and force fluctuations during steady contractions with variable involvement of...

journal_title：Muscle & nerve

authors： Yoshitake Y,Kouzaki M,Fukuoka H,Fukunaga T,Shinohara M

更新日期：2007-06-01 00:00:00

abstract：:Myasthenia gravis (MG) exacerbations may be triggered by infections.In the winter of 2009/2010, the Israeli Ministry of Health recommended that each individual with a chronic condition be vaccinated against both the seasonal influenza and the H1N1 virus. We examined vaccination practices in 74 MG patients. Only 38 pat...

journal_title：Muscle & nerve

authors： Auriel E,Regev K,Dori A,Karni A

更新日期：2011-06-01 00:00:00

abstract：INTRODUCTION:Contradictory reports of the myosin heavy chain (MHC) composition of adult human suprahyoid muscles leave unresolved the extent to which these muscles express developmental and unconventional MHC. METHODS:By immunohistochemistry, separation sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PA...

journal_title：Muscle & nerve

authors： Luo Q,Douglas M,Burkholder T,Sokoloff AJ

更新日期：2014-04-01 00:00:00

abstract：:The cerebrospinal fluid (CSF) of patients with demyelinating neurological disease, such as Guillain-Barré syndrome or multiple sclerosis, contains factors that inhibit the excitatory Na+ current. Such antiexcitatory factors are occasionally also detectable in CSF from patients with other neurological diseases but were...

journal_title：Muscle & nerve

authors： Brinkmeier H,Seewald MJ,Wollinsky KH,Rüdel R

更新日期：1996-01-01 00:00:00

abstract：:Neuromuscular recovery after peripheral nerve lesion depends on the regeneration of severed axons that re-establish their functional connection with the denervated muscle. The aim of this study was to determine the effects of electrical stimulation (ES) on the neuromuscular recovery after nerve crush injury in rats. E...

journal_title：Muscle & nerve

authors： Gigo-Benato D,Russo TL,Geuna S,Domingues NR,Salvini TF,Parizotto NA

更新日期：2010-05-01 00:00:00

abstract：:Three well-characterized antimyosin heavy chain monoclonal antibodies (McAbs) were used as immunocytochemical reagents to study myosin isoform expression in relationship to adenosine triphosphatase (ATPase) defined fiber types in human muscle. The biopsy specimens were from patients with neurogenic muscle disease whos...

journal_title：Muscle & nerve

authors： Sawchak JA,Lewis S,Shafiq SA

更新日期：1989-08-01 00:00:00

abstract：:The F-wave was used to estimate motor nerve conduction velocity (MNCV) along the proximal segment of the fastest axons of the deep peroneal nerve (anterior-horn cells to knee) in 13 patients with amyotrophic lateral sclerosis (ALS) and in 21 age- and sex-matched control subjects. Measurements were based on the shortes...

journal_title：Muscle & nerve

authors： Argyropoulos CJ,Panayiotopoulos CP,Scarpalezos S

更新日期：1978-11-01 00:00:00

abstract：INTRODUCTION:The molecular mechanism of immune-mediated necrotizing myopathy (IMNM) remains unknown. Autophagy impairment, described in autoimmune diseases, is a key process in myofiber protein degradation flux and muscle integrity and has not been studied in IMNM. METHODS:Muscle biopsies from patients with IMNM (n = ...

journal_title：Muscle & nerve

authors： Girolamo F,Lia A,Annese T,Giannini M,Amati A,D'Abbicco D,Tampoia M,Virgintino D,Ribatti D,Serlenga L,Iannone F,Trojano M

更新日期：2019-09-01 00:00:00

abstract：INTRODUCTION:Muscle force generation involves recruitment and firing rate modulation of motor units (MUs). The control of MUs in producing multidirectional forces remains unclear. METHODS:We studied MU recruitment and firing properties, recorded from the first dorsal interosseous muscle, for 3 different directions of ...

journal_title：Muscle & nerve

authors： Lei Y,Suresh NL,Rymer WZ,Hu X

更新日期：2018-01-01 00:00:00

abstract：:There were 31 Duchenne patients placed on overnight mouth intermittent positive pressure ventilation for severe respiratory insufficiency at the average age of 19.9 years. Most patients had vital capacities less than 200 cc at their last evaluations. Of these, 23 patients are alive at the average age of 27 years and l...

journal_title：Muscle & nerve

authors： Bach JR,O'Brien J,Krotenberg R,Alba AS

更新日期：1987-02-01 00:00:00

abstract：:The dystrophin protein complex (DPC), composed of at least 10 proteins that associate with dystrophin, is critical for the maintenance of normal muscle fiber structure and physiology. In this study, we used immunohistochemistry and confocal microscopy to examine the relative abundance and distribution of several of th...

journal_title：Muscle & nerve

authors： Draviam R,Billington L,Senchak A,Hoffman EP,Watkins SC

更新日期：2001-02-01 00:00:00

abstract：INTRODUCTION:Psoriasis is a T-cell-mediated skin disorder with uncommon extracutaneous manifestations. Rare patients with psoriasis and myopathy have been reported. METHODS:We conducted a retrospective review of medical records of psoriasis patients seen at the Mayo Clinic during the period from January 1, 1996 to May...

journal_title：Muscle & nerve

authors： Liewluck T,Ernste FC,Tracy JA

更新日期：2013-11-01 00:00:00

abstract：:The majority of patients with MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes) have an A-->G mutation at nucleotide 3243 in mitochondrial transfer (t)RNA. To date there have only been 10 reported cases of MELAS syndrome in patients with a T-->C mutation at position 3271...

journal_title：Muscle & nerve

authors： Tarnopolsky MA,Maguire J,Myint T,Applegarth D,Robinson BH

更新日期：1998-01-01 00:00:00

abstract：INTRODUCTION:Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, or statins, are widely used drugs for hyperlipidemia and are generally well-tolerated, but the can produce skeletal muscle toxicity. The molecular mechanisms driving statin myopathy are unknown. We investigated the effects of statin treatment...

journal_title：Muscle & nerve

authors： Hubal MJ,Reich KA,De Biase A,Bilbie C,Clarkson PM,Hoffman EP,Thompson PD

更新日期：2011-09-01 00:00:00

abstract：INTRODUCTION:Mutations in the guanosine diphosphate-mannose pyrophosphorylase-B gene (GMPPB) have been identified in congenital muscular dystrophies, limb-girdle muscular dystrophy (LGMD2T), and congenital myasthenic syndromes (CMSs); overall, 41 patients have been described. METHODS:Two patients presented with a myas...

journal_title：Muscle & nerve

authors： Montagnese F,Klupp E,Karampinos DC,Biskup S,Gläser D,Kirschke JS,Schoser B

更新日期：2017-08-01 00:00:00

abstract：INTRODUCTION:We examined the effects of pain site and intensity on function in patients with myotonic dystrophy type 1 (DM1) and facioscapulohumeral muscular dystrophy (FSHD) and chronic pain. METHODS:Questionnaires assessing pain sites, pain extent (number of sites), pain intensity, and pain interference were complet...

journal_title：Muscle & nerve

authors： Miró J,Gertz KJ,Carter GT,Jensen MP

更新日期：2014-06-01 00:00:00

abstract：INTRODUCTION:The current practice of single-fiber electromyography (SFEMG) requires that 20 fiber pairs with normal jitter be collected to exclude myasthenia gravis (MG). We applied principles of futility analysis from clinical trials in an attempt to reduce that requirement. METHODS:We utilized conditional power futi...

journal_title：Muscle & nerve

authors： Narayanaswami P,Pantoja-Galicia N,Betensky RA,Rutkove SB

更新日期：2012-04-01 00:00:00

abstract：:Insights into how the nervous system functions have often sprung from knowledge of the localization of nervous system diseases. Indeed, the recent rebirth of behavioral neurology has been sparked by new insights into the topography of higher cortical functions. Yet, the localization of disease affecting the peripheral...

journal_title：Muscle & nerve

authors： Sabin TD

更新日期：1986-10-01 00:00:00

abstract：:Recent studies on the distribution of labeled endogenous proteins in the experimental neuropathies induced by streoptozotocin diabetes, galactose feeding, zinc pyridinethione, 2,5-hexanedione, acrylamide, and p-bromophenylacetylurea (BPAU) have demonstrated an impaired build up of retrogradely transported material der...

journal_title：Muscle & nerve

authors： Jakobsen J,Brimijoin S,Sidenius P

更新日期：1983-02-01 00:00:00

abstract：INTRODUCTION:Cranial muscle fasciculations may be difficult to detect in amyotrophic lateral sclerosis (ALS). Ultrasound (US) detection of fasciculations in these muscles may have clinical utility. METHODS:Patients with suspected ALS were prospectively enrolled. Nerve conduction studies, needle electromyography (EMG),...

journal_title：Muscle & nerve

authors： O'gorman CM,Weikamp JG,Baria M,Van Den Engel-Hoek L,Kassardjian C,Van Alfen N,Boon AJ

更新日期：2017-12-01 00:00:00