Abstract:
:We investigated factors affecting maximal voluntary torque and the assessment of the level of voluntary drive in the elbow flexor muscles. First, the effective compliance of the system was tested by using single, paired, and trains of four stimuli to measure voluntary activation. At high voluntary torques the responses to all these stimuli were identical, suggesting that single stimuli are adequate for estimating voluntary drive. Second, the contribution of torque from synergist elbow flexor muscles was assessed. In attempted maximal voluntary contractions (MVCs), the voluntary activation of brachioradialis (median 91.5%, range 68.9-100%) was lower than for biceps brachii (median 99.1%, range 78.5-100%; P < 0.01). This suggests extra torque may be generated by brachioradialis during elbow flexion, beyond the torque where biceps brachii is maximally activated. Finally, lengthening of the elbow flexors occurred during MVCs, due to slight shoulder movements. This would allow force to increase independently of an increase in voluntary drive.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Allen GM,McKenzie DK,Gandevia SCdoi
10.1002/(sici)1097-4598(199803)21:3<318::aid-mus5>subject
Has Abstractpub_date
1998-03-01 00:00:00pages
318-28issue
3eissn
0148-639Xissn
1097-4598pii
10.1002/(SICI)1097-4598(199803)21:3<318::AID-MUS5>journal_volume
21pub_type
杂志文章相关文献
MUSCLE & NERVE文献大全abstract::Immunocytochemical analysis of muscle specimens from 5 patients with acute quadriplegic myopathy indictes that depletion of either fast or slow myosin occurs in this disorder. The initial lesion consists of focal myosin loss in nonatrophic fibers. Other structural proteins (actin, titin, nebulin) are spared or affecte...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(SICI)1097-4598(199703)20:3<316::AID-MUS8>
更新日期:1997-03-01 00:00:00
abstract::A new approach to the quantification of fiber type grouping is presented, in which the distribution of histochemical type in a muscle cross section is regarded as a realization of a binary Markov random field (BMRF). Methods for the estimation of the parameters of this model are discussed. The first order BMRF, which ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880150617
更新日期:1992-06-01 00:00:00
abstract::We applied the singular value decomposition (SVD) method to study single motor unit firing patterns. Two projects were carried out: (1) a computer simulation study to confirm the meanings of two SVD parameters, the eigenvalue corresponding to the positive-slope eigenvector (PEV) and that corresponding to the negative-...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/1097-4598(200007)23:7<1057::aid-mus8>3.0.c
更新日期:2000-07-01 00:00:00
abstract::Three children presented at birth with axial hypotonia and symmetrical flaccid paresis limited to the upper extremities, and involving proximal and distal muscle groups. At birth, palmar flexion creases were poorly developed, and the hand muscles were atrophic. These clinical features, the muscle biopsy findings, and ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880040205
更新日期:1981-03-01 00:00:00
abstract::Loss of cells from the motor system occurs during the normal aging process, leading to reduction in the complement of motor neurons and muscle fibers. The latter age-related decrease in muscle mass has been termed "sarcopenia" and is often combined with the detrimental effects of a sedentary lifestyle in older adults,...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.1215
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Ankle foot orthoses (AFOs) are commonly prescribed to individuals with Charcot-Marie-Tooth disease (CMT). The aim of this study was to evaluate patient reported satisfaction with orthotic devices and services in individuals with CMT to provide preliminary data for advancing AFO development and improving clin...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.27027
更新日期:2021-01-01 00:00:00
abstract::Previous studies suggest that the muscle fiber lysosome system plays a central role in the increased formation of autophagosomes and autolysosomes that occurs in the context of chloroquine-induced myopathy. The goal of this study was to characterize the contribution of receptor-mediated intracellular transport, partic...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20288
更新日期:2005-04-01 00:00:00
abstract:INTRODUCTION:We investigated the viscoelastic stress relaxation response before and after a 10-week hamstrings static stretch program. METHODS:The maximal range of motion (ROMmax ) and maximal torque (Torquemax ) were assessed before and after a 10-week stretching program. Six 30-s static stretches at a predetermined ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24593
更新日期:2015-05-01 00:00:00
abstract::Superimposed electrical stimulation techniques can be used to detect central activation failure (CAF), that is, incomplete central nervous system recruitment or suboptimal activation of motor units. The purpose of this study was to evaluate the effects of two stimulation parameters on perceived discomfort and torque i...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10289
更新日期:2003-01-01 00:00:00
abstract:INTRODUCTION:We examined the extent to which fatiguing cycling exercise in the heat influences contractile function in modulating the force-frequency relationship. METHODS:Before (∽37.0 °C) and after (∽38.5 °C) exercise (ExH) and passive (PaH) hyperthermia, an 8-s train of stimulation at 10, 20, 50, and 100 Hz (2 s pe...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24228
更新日期:2014-11-01 00:00:00
abstract::An infant presented with congenital weakness, hypotonia, arthrogryposis, atrial tachycardia, and a left intra-abdominal neuroblastoma. Muscle biopsy revealed marked excess of muscle spindles with atrophy of extrafusal fibers. The patient expired at age 14 months from progressive cardiorespiratory failure. Postmortem e...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/1097-4598(200101)24:1<138::aid-mus22>3.0.c
更新日期:2001-01-01 00:00:00
abstract:INTRODUCTION:Are there electrophysiological findings that predict response to intravenous immunoglobulin (IVIg) in patients with lower motor neuron (LMN) syndromes without multifocal conduction block (MCB)? METHODS:We enrolled 9 patients with LMN syndromes without MCB to receive 18 weeks of IVIg therapy. Response was ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21914
更新日期:2011-04-01 00:00:00
abstract::The aim of this study was to investigate in control subjects the effect of imagery training on the torque of plantar-flexor muscles of the ankle. Twenty-nine subjects were allocated to one of three groups that performed either imagery training, low-intensity strength training, or no training (only measurements). The l...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/mus.10406
更新日期:2003-08-01 00:00:00
abstract:INTRODUCTION:Previous studies have reported higher wrist ratios (WR) related to carpal tunnel syndrome (CTS) but have not assessed effect modification by obesity and may have inadequately controlled for confounders. METHODS:Baseline data of a multicenter prospective cohort study were analyzed. CTS was defined by nerve...
journal_title:Muscle & nerve
pub_type: 杂志文章,多中心研究
doi:10.1002/mus.25692
更新日期:2017-12-01 00:00:00
abstract::The synthesized pyrimidine compound MS-818 has neurotrophic effects in several kinds of neuronal cells, but its effect with respect to muscle cells remains unknown. We therefore examined the effects of MS-818 on regeneration for 12 weeks in a wounded area (damaged and gap areas) of cut muscle in adult rats. The right ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10028
更新日期:2002-02-01 00:00:00
abstract:INTRODUCTION:Twenty-six patients with clinical symptoms of adult onset carnitine palmitoyltransferase II (CPTII) deficiency were examined. All patients had skeletal muscle CPTII enzyme activity levels indicative of heterozygosity for CPT2 mutations, however sequence analysis identified no pathogenic mutations within th...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23498
更新日期:2013-02-01 00:00:00
abstract::Doxorubicin is a chemotherapeutic agent prescribed for a variety of tumors. While undergoing treatment, patients exhibit frequent symptoms that suggest respiratory muscle weakness. Cancer patients can receive doxorubicin chemotherapy through either intravenous (IV) or intraperitoneal (IP) injections. We hypothesized t...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21809
更新日期:2011-01-01 00:00:00
abstract::Patients with an idiopathic increase in serum creatine kinase (CK) levels (hyper-CK-emia) have a benign prognosis, but symptoms may be disabling in daily life. Previous studies have suggested that physical exercise increases the severity of complaints in these patients. We studied whether maximal and submaximal bouts ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10232
更新日期:2002-12-01 00:00:00
abstract::We developed electrophysiologic methods for testing the three major forelimb nerves as a tool to evaluate motor and sensory recovery in rats. Median, ulnar, or radial nerves were transected and repaired in Sprague-Dawley rats. Compound muscle action potentials (CMAPs) and somatosensory evoked potentials (SSEPs) were r...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20971
更新日期:2008-10-01 00:00:00
abstract::We examined and compared a mechanosensitive human sural neuroma and a contralateral sural nerve collected simultaneously from a patient involved in a diabetic neuropathy research protocol. Using indirect immunofluorescence staining. we identified a striking difference in the content within axons of two neuropeptides, ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199707)20:7<875::aid-mus12
更新日期:1997-07-01 00:00:00
abstract::To clarify the molecular nature of the pathogenesis in X-linked Emery-Dreifuss muscular dystrophy (EDMD), we monitored the expression of 2400 genes in control and EDMD fibroblasts by using complementary DNA (cDNA) microarray techniques. A total of 60 genes whose expression was altered in EDMD fibroblasts when compared...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10085
更新日期:2002-06-01 00:00:00
abstract::The cerebrospinal fluid (CSF) of patients with demyelinating neurological disease, such as Guillain-Barré syndrome or multiple sclerosis, contains factors that inhibit the excitatory Na+ current. Such antiexcitatory factors are occasionally also detectable in CSF from patients with other neurological diseases but were...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(SICI)1097-4598(199601)19:1<54::AID-MUS7>3
更新日期:1996-01-01 00:00:00
abstract::The purpose of this long-term, open parallel-group, double-consent study of alternate-day, low-dose prednisone in 2-4-year-old patients with Duchenne muscular dystrophy (DMD) was to determine whether prednisone produces a beneficial effect when given earlier than usual. Muscle function was evaluated by timed tests, an...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/mus.10319
更新日期:2003-02-01 00:00:00
abstract::Normal motor units (MUs) were simulated and their architecture altered to simulate the changes produced by myopathy. The concentric needle electromyographic recordings of motor unit action potentials (MUAPs) from the MUs were then also simulated. These simulated MUAPs showed features that are seen in myopathy: normal ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880120306
更新日期:1989-03-01 00:00:00
abstract::Isometric contractile properties of human elbow flexor muscles were examined in 27 normal subjects (7 females and 20 males). Contractions of elbow flexors were elicited by application of electrical pulses to the biceps motor points. The tension development was recorded at the wrist with the elbow angle fixed at 90 deg...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880040307
更新日期:1981-05-01 00:00:00
abstract::Electrophysiologic findings in thallium intoxication are usually untimely, limited in extent, and often uninformative. This report documents serial conduction and electromyographic findings in a case of thallium poisoning, beginning 10 days after symptom onset and ending 24 months later. Initially, the plantar nerves ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880130510
更新日期:1990-05-01 00:00:00
abstract::Peripheral nerve lesions are sometimes associated with focal dystonia. We diagnosed ulnar neuropathy in 28 of 73 (40%) cases of occupational cramp in musicians. Focal slowing of ulnar conduction across the elbow was identified in 15 of 19 (79%) patients using the near nerve technique and in 5 of 17 (29%) patients usin...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880190403
更新日期:1996-04-01 00:00:00
abstract::To determine if short TI (time to inversion) recovery (STIR) magnetic resonance imaging (MRI) is useful in assessing lower extremity (LE) denervation in subacute lumbar radiculopathy (LR), 25 subjects underwent lumbar spine MRI, LE STIR MRI and needle electromyography (EMG). In 23 (92%) subjects there was a positive c...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199709)20:9<1191::aid-mus1
更新日期:1997-09-01 00:00:00
abstract::We present the case of a 37-year-old Afghani man with a history of childhood diphtheria, who was diagnosed with bilateral vocal cord paralysis at age 15 years. At about this time he developed progressive muscular wasting and distally predominant weakness, and subsequently developed respiratory insufficiency, necessita...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(200001)23:1<132::aid-mus21
更新日期:2000-01-01 00:00:00
abstract::Abnormalities of GM2 ganglioside metabolism owing to hexosaminidase A (Hex A) deficiency have been associated with ALS phenotypes. The clinical features described in these ALS patients with Hex A deficiency include early onset, positive family history, and/or long disease duration. In an attempt to determine prospecti...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880110307
更新日期:1988-03-01 00:00:00