Abstract:
:We present three new and 14 retrospective cases of polyradiculopathy in sarcoidosis. Of these, 71% had weakness and 59% areflexia of the lower extremities, and 35% had sphincter dysfunction. Cases often were associated with central nervous system sarcoidosis. All cases involved thoracolumbar or lumbosacral roots, except a single case of cervical polyradiculopathy. Of 14 treated patients, nine improved with corticosteroids, laminectomy, or both. Polyradiculopathy complicating sarcoidosis: (1) is uncommon; (2) primarily involves thoracic and lumbar roots; (3) may arise from contiguous, hematogenous, or gravitational nerve root sleeve seeding; (4) may be asymptomatic; and (5) may improve with corticosteroids. Differential diagnosis of weakness in patients with sarcoidosis should include nerve root involvement from the primary process by direct sarcoid involvement.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Koffman B,Junck L,Elias SB,Feit HW,Levine SRdoi
10.1002/(sici)1097-4598(199905)22:5<608::aid-mus9>subject
Has Abstractpub_date
1999-05-01 00:00:00pages
608-13issue
5eissn
0148-639Xissn
1097-4598pii
10.1002/(SICI)1097-4598(199905)22:5<608::AID-MUS9>journal_volume
22pub_type
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