Polyradiculopathy in sarcoidosis.

Abstract:

:We present three new and 14 retrospective cases of polyradiculopathy in sarcoidosis. Of these, 71% had weakness and 59% areflexia of the lower extremities, and 35% had sphincter dysfunction. Cases often were associated with central nervous system sarcoidosis. All cases involved thoracolumbar or lumbosacral roots, except a single case of cervical polyradiculopathy. Of 14 treated patients, nine improved with corticosteroids, laminectomy, or both. Polyradiculopathy complicating sarcoidosis: (1) is uncommon; (2) primarily involves thoracic and lumbar roots; (3) may arise from contiguous, hematogenous, or gravitational nerve root sleeve seeding; (4) may be asymptomatic; and (5) may improve with corticosteroids. Differential diagnosis of weakness in patients with sarcoidosis should include nerve root involvement from the primary process by direct sarcoid involvement.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Koffman B,Junck L,Elias SB,Feit HW,Levine SR

doi

10.1002/(sici)1097-4598(199905)22:5<608::aid-mus9>

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

608-13

issue

5

eissn

0148-639X

issn

1097-4598

pii

10.1002/(SICI)1097-4598(199905)22:5<608::AID-MUS9>

journal_volume

22

pub_type

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