Calf enlargement in hereditary motor and sensory neuropathy.

abstract：INTRODUCTION:We sought to determine the specificity of compound muscle action potential (CMAP) durations and amplitudes in a large critical illness neuromyopathy (CINM) cohort relative to controls with other neuromuscular conditions. METHODS:Fifty-eight patients with CINM who had been seen over a 17-year period were r...

journal_title：Muscle & nerve

authors： Kramer CL,Boon AJ,Harper CM,Goodman BP

更新日期：2018-03-01 00:00:00

abstract：:Type-specific antibodies to the polymorphic types of collagen have been used to study their distribution in polymyositis. Dramatic increases were observed in the staining with antibodies to Type III collagen and, to a lesser extent, with antibodies to Types I, IV, and V. The changes in capillary and endomysial basemen...

journal_title：Muscle & nerve

authors： Duance VC,Black CM,Dubowitz V,Hughes GR,Bailey AJ

更新日期：1980-11-01 00:00:00

abstract：INTRODUCTION:Neuromuscular activation can be influenced by both muscle temperature (Tm) and fatigue. METHODS:To assess the effects of Tm and fatigue on the electromechanical delay (EMD), 15 participants performed voluntary isometric contractions of different intensities under neutral (TmN), low (TmL), and high (TmH) T...

journal_title：Muscle & nerve

authors： Cè E,Rampichini S,Agnello L,Limonta E,Veicsteinas A,Esposito F

更新日期：2013-04-01 00:00:00

abstract：:The values obtained from two different macro EMG methods were compared, and found to be different. Normally, macro electromyography (EMG) is performed with a modified single fiber (SF) needle using the SF potential as a trigger; a new method recommends a modified concentric needle and triggers on the concentric EMG si...

journal_title：Muscle & nerve

authors： Nix WA,Scherer A

更新日期：1992-02-01 00:00:00

abstract：:The role of motor innervation and muscle tension in the posthatching maturation of the slow-tonic anterior latissimus dorsi (ALD) muscle of the chicken has been investigated. Modification of the muscle tension was obtained either by maintaining ALD in a shortened state or by stretching, after or without denervation. I...

journal_title：Muscle & nerve

authors： Gardahaut MF,Rouaud TP,Renaud D,Khaskiye A,Le Douarin GH

更新日期：1989-11-01 00:00:00

abstract：:Clinicopathologic findings from two golden retriever dogs with an inherited, progressive, degenerative muscle disease that were studied until 27 and 40 months of age are described. Initial clinical signs included stilted gait and simultaneous advancement of their pelvic limbs. Further gait restriction and muscle hyper...

journal_title：Muscle & nerve

authors： Kornegay JN,Tuler SM,Miller DM,Levesque DC

更新日期：1988-10-01 00:00:00

abstract：INTRODUCTION:Rapid and accessible methods for diagnosing diabetic polyneuropathy (DPN) have been developed, but not validated, in large cohorts of people with diabetes. METHODS:The performance of a point-of-care device (POCD) was studied in 168 patients with type 2 diabetes, estimating the sensitivity, specificity, po...

journal_title：Muscle & nerve

authors： Kural MA,Andersen ST,Andersen NT,Andersen H,Charles M,Finnerup NB,Jensen TS,Tankisi H

更新日期：2019-02-01 00:00:00

abstract：:We describe two cases of neuralgic amyotrophy with electrophysiological evidence of conduction block across the lower trunk of the brachial plexus. Low-output impedance stimulation of the cervical spinal roots in combination with collision was used to accurately demonstrate the conduction block. Complete electrophysio...

journal_title：Muscle & nerve

authors： Watson BV,Nicolle MW,Brown JD

更新日期：2001-04-01 00:00:00

abstract：:To determine the contributions of neural and mechanical mechanisms to the limits in the range of motion (ROM) about a joint, we studied the effects of 30 sessions of static stretch training on the characteristics of the plantar-flexor muscles in 12 subjects. Changes in the maximal ankle dorsiflexion and the torque pro...

journal_title：Muscle & nerve

authors： Guissard N,Duchateau J

更新日期：2004-02-01 00:00:00

abstract：:The sternocleidomastoid muscle (SCM) is one of the major muscles involved in producing abnormal head position in cervical dystonia patients. This study tested whether doxorubicin chemomyectomy, direct injection of doxorubicin into the SCM to permanently remove muscle fibers, has the potential to be a nonsurgical, perm...

journal_title：Muscle & nerve

authors： McLoon LK,Falkenberg JH,Dykstra D,Iaizzo PA

更新日期：1998-11-01 00:00:00

abstract：INTRODUCTION:Doppler ultrasonography (DU) has recently been shown to be useful in imaging carpal tunnel syndrome (CTS). In this study, we aim to characterize the changes seen after exercise and electrical stimulation. METHODS:Five patients with CTS were recruited with 5 age-matched subjects. DU was used to visualize t...

journal_title：Muscle & nerve

authors： Ng ES,Ng KW,Wilder-Smith EP

更新日期：2013-01-01 00:00:00

abstract：:Exercise intolerance with myalgia, muscle stiffness, and recurrent rhabdomyolysis due to mutations in the DMD gene can mimic metabolic myopathies leading to delayed or inaccurate diagnoses. In this retrospective chart review, we report 3 unrelated boys with exertional myalgia, muscle stiffness, myoglobinuria, and norm...

journal_title：Muscle & nerve

authors： Veerapandiyan A,Shashi V,Jiang YH,Gallentine WB,Schoch K,Smith EC

更新日期：2010-12-01 00:00:00

abstract：:Three cases of chronic distal sensorimotor neuropathy are described in patients with neurofibromatosis. One had type 2 or central neurofibromatosis with a chromosome 22 deletion; the precise form of the disease was not established in the other two. A striking clinical feature was a diffuse nodular enlargement of the p...

journal_title：Muscle & nerve

authors： Thomas PK,King RH,Chiang TR,Scaravilli F,Sharma AK,Downie AW

更新日期：1990-02-01 00:00:00

abstract：:Ion channels are complex proteins that span the lipid bilayer of the cell membrane, where they orchestrate the electrical signals necessary for normal function of the central nervous system, peripheral nerve, and both skeletal and cardiac muscle. The role of ion channel defects in the pathogenesis of numerous disorder...

journal_title：Muscle & nerve

authors： Kleopa KA,Barchi RL

更新日期：2002-09-01 00:00:00

abstract：INTRODUCTION:X-linked myotubular myopathy (XLMTM), characterized by severe hypotonia, weakness, respiratory distress, and early mortality, is rare and natural history studies are few. METHODS:RECENSUS is a multicenter chart review of male XLMTM patients characterizing disease burden and unmet medical needs. Data were ...

journal_title：Muscle & nerve

authors： Beggs AH,Byrne BJ,De Chastonay S,Haselkorn T,Hughes I,James ES,Kuntz NL,Simon J,Swanson LC,Yang ML,Yu ZF,Yum SW,Prasad S

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Valosin-containing protein (VCP) variants that affect muscle, bone, and the nervous system are termed multisystem proteinopathy. VCP myopathy is manifested as limb-girdle weakness, distal weakness and scapuloperoneal weakness. METHODS:We reviewed clinical, genetic, and muscle biopsy data from 6 members of...

journal_title：Muscle & nerve

authors： Guo X,Zhao Z,Shen H,Qi B,Li N,Hu J

更新日期：2019-03-01 00:00:00

abstract：:Guillain-Barré syndrome (GBS) generally presents sporadically. Epidemics of GBS are unusual. We reviewed the medical records of 26 patients hospitalized for GBS during the 2007 GBS epidemic in northeast China. The objective was to determine whether there were clinical and electrophysiological characteristics. All pati...

journal_title：Muscle & nerve

authors： Ye Y,Zhu D,Wang K,Wu J,Feng J,Ma D,Xing Y,Jiang X

更新日期：2010-09-01 00:00:00

abstract：:Muscle cramps are difficult to study scientifically because of their spontaneity and unpredictability. Various laboratory techniques to induce muscle cramps have been explored but the best technique for inducing cramps is unclear. Electrical stimulation appears to be the most reliable, but there is a perception that i...

journal_title：Muscle & nerve

authors： Miller KC,Knight KL

更新日期：2007-11-01 00:00:00

abstract：:To investigate the role of the thymus in the pathogenesis of myasthenia gravis (MG), immunohistochemical expression of CD44, CD45R0, B7-1, and IL-2 was studied in: (1) hyperplastic thymuses of patients with MG whose symptoms markedly improved after thymectomy, (2) remnant thymuses of patients with MG whose symptoms di...

journal_title：Muscle & nerve

authors： Utsugisawa K,Nagane Y,Tohgi H

更新日期：2000-04-01 00:00:00

abstract：INTRODUCTION:In this study we estimated the costs paid by U.S. health plans for treating myasthenia gravis (MG) in 2009 and determined the major cost drivers. METHODS:One hundred thirteen MG patients were matched by propensity scores with 339 non-MG patients from a comprehensive health-care insurance database. The mea...

journal_title：Muscle & nerve

authors： Guptill JT,Sharma BK,Marano A,Soucy A,Krueger A,Sanders DB

更新日期：2012-03-01 00:00:00

abstract：:To evaluate the effect of SMN2 copy number on disease severity in spinal muscular atrophy (SMA), we stratified 45 adult SMA patients based on SMN2 copy number (3 vs. 4 copies). Patients with 3 copies had an earlier age of onset and lower spinal muscular atrophy functional rating scale (SMAFRS) scores and were more lik...

journal_title：Muscle & nerve

authors： Elsheikh B,Prior T,Zhang X,Miller R,Kolb SJ,Moore D,Bradley W,Barohn R,Bryan W,Gelinas D,Iannaccone S,Leshner R,Mendell JR,Mendoza M,Russman B,Smith S,King W,Kissel JT

更新日期：2009-10-01 00:00:00

abstract：:Electron microscopic studies of long-term denervated rat muscles have identified very small, immature myofibers that are believed to arise from detached satellite cells that have fused to form new fibers within the interstitial space. At present, it is unknown whether and to what extent equivalent fibers exist in dene...

journal_title：Muscle & nerve

authors： Doppler K,Mittelbronn M,Bornemann A

更新日期：2008-01-01 00:00:00

abstract：:We have developed an algorithm, called multi-motor unit action potential analysis (MMA), to aid quantification in routine needle EMG examination. In only 5-8 min, it was possible to extract, analyze, and validate 20 motor unit action potentials (MUAPs). In the biceps muscle of normal subjects, the MUAP measurements ar...

journal_title：Muscle & nerve

authors： Nandedkar SD,Barkhaus PE,Charles A

更新日期：1995-10-01 00:00:00

abstract：:In a reported patient with myopathic carnitine deficiency, addition of exogenous carnitine to muscle homogenates failed to correct palmitate oxidation, and oral carnitine was of no clinical benefit. In a muscle biopsy from this patient, we found that, in contrast to the marked deficiency of free carnitine (3% of norma...

journal_title：Muscle & nerve

authors： Trevisan CP,Reichmann H,DeVivo DC,DiMauro S

更新日期：1985-10-01 00:00:00

abstract：:Conduction velocity of A delta fibers of the human peripheral nerves was measured by using pain-related somatosensory evoked potentials following CO2 laser stimulation. It was found to be approximately 9 m/s in the forearm as well as in the lower leg. Because conventional conduction study using electric stimulation re...

journal_title：Muscle & nerve

authors： Kakigi R,Endo C,Neshige R,Kuroda Y,Shibasaki H

更新日期：1991-12-01 00:00:00

abstract：:Polylysines, polyornithine, and protamine increased the release of creatine kinase (CK) and lactate dehydrogenase (LDH) from frog muscles. With 5 micrograms/ml (50 nM) of a polylysine of molecular weight 100,000, enzyme release reached peak values (ten-fold above control) within 30 minutes; subsequent removal of the p...

journal_title：Muscle & nerve

authors： Suarez-Kurtz G

更新日期：1985-02-01 00:00:00

abstract：INTRODUCTION:We report preliminary findings of nerve ultrasound in patients with cerebellar ataxia neuropathy vestibular areflexia syndrome (CANVAS) who have sensory impairment due to dorsal root ganglionopathy. METHODS:The ultrasound cross-sectional area (CSA) of median and ulnar nerves of 7 CANVAS patients was compa...

journal_title：Muscle & nerve

authors： Pelosi L,Leadbetter R,Mulroy E,Chancellor AM,Mossman S,Roxburgh R

更新日期：2017-07-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to determine the impact of an in-home expiratory muscle strength training (EMST) program on pulmonary, swallow, and cough function in individuals with amyotrophic lateral sclerosis (ALS). METHODS:EMST was tested in a prospective, single-center, double-blind, randomized, contr...

journal_title：Muscle & nerve

authors： Plowman EK,Tabor-Gray L,Rosado KM,Vasilopoulos T,Robison R,Chapin JL,Gaziano J,Vu T,Gooch C

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Slowly progressive, genetic neuromuscular diseases (gNMDs) often lead to important motor deficiencies and functional limitations. The Quality of Life in Genetic Neuromuscular Disease Questionnaire (QoL-gNMD) is a new health-related quality-of-life questionnaire developed for these patients. The purpose of ...

journal_title：Muscle & nerve

authors： Dany A,Rapin A,Lavrard B,Saoût V,Réveillère C,Bassez G,Tiffreau V,Péréon Y,Sacconi S,Eymard B,Dramé M,Jolly D,Novella JL,Hardouin JB,Boyer FC

更新日期：2017-12-01 00:00:00

abstract：:Autosomal dominant oculopharyngeal muscular dystrophy (OPMD) is an adult-onset disease caused by (GCG) repeat expansions in exon 1 of the poly(A) binding protein 2 gene (PABP2). To elucidate the molecular mechanism underlying the disease, we raised an antiserum against a synthetic peptide fragment predicted from PABP2...

journal_title：Muscle & nerve

authors： Uyama E,Tsukahara T,Goto K,Kurano Y,Ogawa M,Kim YJ,Uchino M,Arahata K

更新日期：2000-10-01 00:00:00