Impact of expiratory strength training in amyotrophic lateral sclerosis: Results of a randomized, sham-controlled trial.

abstract：INTRODUCTION:Transitioning from adolescence to adulthood can be problematic for individuals with rare disabilities such as muscular dystrophy (MD). METHODS:We identified a cohort of 220 individuals with MD and 440 matched comparison individuals and measured emergency room (ER) and inpatient (IP) encounters for the yea...

journal_title：Muscle & nerve

authors： Mann JR,Royer JA,Mcdermott S,Hardin JW,Ozturk O,Street N

更新日期：2015-11-01 00:00:00

abstract：INTRODUCTION:Amyotrophic lateral sclerosis (ALS) is a debilitating neurologic disorder with poor survival rates and no clear biomarkers for disease diagnosis and prognosis. METHODS:We compared serum microRNA (miRNA) expression from patients with ALS with healthy controls and patients with multiple sclerosis and Alzhei...

journal_title：Muscle & nerve

authors： Raheja R,Regev K,Healy BC,Mazzola MA,Beynon V,Von Glehn F,Paul A,Diaz-Cruz C,Gholipour T,Glanz BI,Kivisakk P,Chitnis T,Weiner HL,Berry JD,Gandhi R

更新日期：2018-08-01 00:00:00

abstract：:False motor points (FMPs) can occur in intrinsic foot or hand muscles, causing spuriously prolonged distal motor latencies by misrepresenting the compound muscle action potential (CMAP) onset. We investigated the motor point (MP) and possible FMPs in abductor hallucis (AH) by three methods: (1) electrophysiologic mapp...

journal_title：Muscle & nerve

authors： Del Toro DR,Park TA

更新日期：1996-09-01 00:00:00

abstract：:In order to assess the clinical utility of trigemino-facial reflexes in lower facial muscles, we studied perioral reflexes to mechanical and electrical stimulation in 13 patients with spasmodic dysphonia and orofacial dyskinesia and in 7 healthy subjects. Mechanical stimulation of the upper lip of all patients and ele...

journal_title：Muscle & nerve

authors： Topka H,Hallett M

更新日期：1992-09-01 00:00:00

abstract：INTRODUCTION:Electrical stimulation of denervated muscle has been shown to minimize atrophy and fibrosis and increase force in animal and human models. However, electrical stimulation after nerve repair is controversial due to questions of efficacy. METHODS:Using a rat model, we investigated the efficacy of short-term...

journal_title：Muscle & nerve

authors： Willand MP,Holmes M,Bain JR,Fahnestock M,De Bruin H

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:We aimed at evaluating the differential involvement of large myelinated Aβ-, small myelinated Aδ-, and unmyelinated C-fibers in patients with diabetic polyneuropathy and how they contribute to neuropathic pain. METHODS:We collected clinical and diagnostic test variables in 133 consecutive patients with diab...

journal_title：Muscle & nerve

authors： Galosi E,Di Pietro G,La Cesa S,Di Stefano G,Leone C,Fasolino A,Di Lionardo A,Leonetti F,Buzzetti R,Mollica C,Cruccu G,Truini A

更新日期：2021-01-01 00:00:00

abstract：:The F-wave was used to estimate the fastest motor nerve conduction velocity (MNCV) along the proximal segment (spinal cord to knee) of the axons of the tibial nerve in 65 control subjects, 8 patients with diabetic polyneuropathy, and 4 patients with Charcot-Marie-Tooth disease. Terminal latencies and MNCV along the di...

journal_title：Muscle & nerve

authors： Panayiotopoulos CP,Scarpalezos S,Nastas PE

更新日期：1978-05-01 00:00:00

abstract：:We describe a patient with a clinical disorder that resembled vasculitic neuropathy in which peripheral nerves were successively affected over several months, but without systemic involvement. An initial muscle biopsy near the involved nerves showed signs of nonspecific inflammation around the muscle and nerve fibers....

journal_title：Muscle & nerve

authors： Kuntzer T,Lobrinus JA,Janzer RC,Ghika J,Bogousslavsky J

更新日期：2000-10-01 00:00:00

abstract：INTRODUCTION:Measurement precision and accuracy of spinal reflexes plays an essential role in the clinical neurological examination. Reflexes are conventionally assessed either electromyographically or with rating scales. In this study we compared objective kinematic T-reflex and subjective assessments of patellar refl...

journal_title：Muscle & nerve

authors： Dafkin C,Green A,Kerr S,Veliotes D,McKinon W

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Neutral lipid-storage disease with myopathy is caused by mutations in PNPLA2, which produce skeletal and cardiac myopathy. We report a man with multiorgan neutral lipid storage and unusual multisystem clinical involvement, including cognitive impairment. METHODS:Quantitative brain MRI with voxel-based mor...

journal_title：Muscle & nerve

authors： Massa R,Pozzessere S,Rastelli E,Serra L,Terracciano C,Gibellini M,Bozzali M,Arca M

更新日期：2016-04-01 00:00:00

abstract：:Neuromuscular recovery after peripheral nerve lesion depends on the regeneration of severed axons that re-establish their functional connection with the denervated muscle. The aim of this study was to determine the effects of electrical stimulation (ES) on the neuromuscular recovery after nerve crush injury in rats. E...

journal_title：Muscle & nerve

authors： Gigo-Benato D,Russo TL,Geuna S,Domingues NR,Salvini TF,Parizotto NA

更新日期：2010-05-01 00:00:00

abstract：:The selection of patients who will benefit from peripheral nerve surgery continues to evolve. The evaluation of patients with peripheral nerve problems, and the indications and timing of surgery are reviewed. This includes patients with transections, lesions in continuity, entrapments, tumors, injection injuries, and ...

journal_title：Muscle & nerve

authors： Spinner RJ,Kline DG

更新日期：2000-05-01 00:00:00

abstract：:Genetic testing is rapidly becoming an increasingly significant part of the diagnostic armamentarium of neuromuscular clinicians. Although technically easy to order, the results of such testing, whether positive or negative, have potentially enormous consequences for the individual tested and for family members. As a ...

journal_title：Muscle & nerve

authors： Su X,Kang PB,Russell JA,Simmons Z

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Low-intensity electrical stimuli of digital nerves may generate a double peak potential (DPp), composed of a cathodal (caAP) and an anodal (anAP) potential in orthodromic recordings. METHODS:We studied the effects on caAP and anAP of stimuli of variable intensity, duration, and frequency. We also applied ...

journal_title：Muscle & nerve

authors： Leote J,Pereira P,Cabib C,Cipullo F,Valls-Sole J

更新日期：2016-06-01 00:00:00

abstract：:Loss of cells from the motor system occurs during the normal aging process, leading to reduction in the complement of motor neurons and muscle fibers. The latter age-related decrease in muscle mass has been termed "sarcopenia" and is often combined with the detrimental effects of a sedentary lifestyle in older adults,...

journal_title：Muscle & nerve

authors： Vandervoort AA

更新日期：2002-01-01 00:00:00

abstract：INTRODUCTION:In compressive neuropathies, large myelinated nerve fibers are generally thought to be more susceptible. In this study, we investigated small myelinated Aδ and unmyelinated C fiber function in patients with mild, moderate, and severe carpal tunnel syndrome. METHODS:Forty-four healthy controls and 81 carpa...

journal_title：Muscle & nerve

authors： Clarke C,Christensen C,Curran MWT,Chan KM

更新日期：2017-10-01 00:00:00

abstract：:Neuroinflammation is a characteristic of pathologically affected tissue in several neurodegenerative disorders. These changes can be observed in the brainstem and spinal cord of amyotrophic lateral sclerosis (ALS) cases and in mouse models of the disease. They include an accumulation of large numbers of activated micr...

journal_title：Muscle & nerve

authors： McGeer PL,McGeer EG

更新日期：2002-10-01 00:00:00

abstract：:The objective of this study was to examine the contribution of lower motor neuron (LMN) and upper motor neuron (UMN) dysfunction to weakness and impaired motor control in 27 patients with amyotrophic lateral sclerosis (ALS). Isometric strength was measured by dorsiflexor maximum voluntary contraction force (MVC). LMN ...

journal_title：Muscle & nerve

authors： Kent-Braun JA,Walker CH,Weiner MW,Miller RG

更新日期：1998-06-01 00:00:00

abstract：INTRODUCTION:Neuralgic amyotrophy (NA) often imposes diagnostic problems. Recently, MRI and high-resolution ultrasound (HRUS) have proven useful in diagnosing peripheral nerve disorders. METHODS:We performed a chart and imaging review of patients who were examined using neuroimaging and who were referred because of cl...

journal_title：Muscle & nerve

authors： Lieba-Samal D,Jengojan S,Kasprian G,Wöber C,Bodner G

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Symptoms often return in patients with carpal tunnel syndrome (CTS) who are treated with a local corticosteroid injection. We aimed to determine prognostic factors for a successful long-term outcome. METHODS:We prospectively followed 113 patients who received an injection for CTS. Clinical, electrophysiol...

journal_title：Muscle & nerve

authors： Meys V,Thissen S,Rozeman S,Beekman R

更新日期：2011-11-01 00:00:00

abstract：:Electrodiagnostic findings of fibrillations and positive sharp waves in the lumbosacral paraspinals in patients without previous back surgery has been generally considered to be abnormal, consistent with posterior rami denervation. In some cases, it is the only abnormality on the electromyographic examination. This st...

journal_title：Muscle & nerve

authors： Date ES,Mar EY,Bugola MR,Teraoka JK

更新日期：1996-03-01 00:00:00

abstract：INTRODUCTION:Merkel cell carcinoma is a rare cutaneous, aggressive tumor. Although it shares many neuroendocrine features with small cell lung carcinoma, it has only occasionally been reported with paraneoplastic neurological syndromes. METHODS:A healthy 67-year-old man developed acute ataxia, vertigo, and nausea. Sub...

journal_title：Muscle & nerve

authors： Pavolucci L,Giannini G,Giannoccaro MP,Foschini MP,Lang B,Avoni P,Tinuper P,Vincent A,Liguori R

更新日期：2017-11-01 00:00:00

abstract：:We describe two cases of neuralgic amyotrophy with electrophysiological evidence of conduction block across the lower trunk of the brachial plexus. Low-output impedance stimulation of the cervical spinal roots in combination with collision was used to accurately demonstrate the conduction block. Complete electrophysio...

journal_title：Muscle & nerve

authors： Watson BV,Nicolle MW,Brown JD

更新日期：2001-04-01 00:00:00

abstract：:We investigated the efficacy of different frequencies and intensities of magnetic stimulation for activating the quadriceps muscles; a painless method for stimulating the quadriceps would be useful in the rehabilitation of patients who have difficulty in voluntarily activating their muscles after injury or surgery. El...

journal_title：Muscle & nerve

authors： Kremenic IJ,Ben-Avi SS,Leonhardt D,McHugh MP

更新日期：2004-09-01 00:00:00

abstract：:Motor unit (MU) number and size estimates were obtained from the human flexor digiti minimi muscle using histological methods. Ten adult fresh cadavers (33-74 years old) were used. The number of MUs was 130 +/- 15 and the MU size was 108 +/- 10. These values are similar to those reported for other hypothenar muscles, ...

journal_title：Muscle & nerve

authors： Santo Neto H,de Carvalho VC,Marques MJ

更新日期：1998-01-01 00:00:00

abstract：INTRODUCTION:Pneumothorax is a potentially serious complication of electromyography (EMG). Data on the frequency of pneumothorax after EMG are lacking. The purpose of this study was to determine the frequency, timing, and risk factors for iatrogenic pneumothorax after EMG. METHODS:Cases of pneumothorax after EMG were ...

journal_title：Muscle & nerve

authors： Kassardjian CD,O'gorman CM,Sorenson EJ

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:We aimed to describe the electrophysiological progression rate of chronic idiopathic axonal polyneuropathy (CIAP) and look into the potential role of human leukocyte antigen (HLA) genetic susceptibility in its development. METHODS:We recruited 57 patients with CIAP (mean age at diagnosis 67, mean follow-up ...

journal_title：Muscle & nerve

authors： Zis P,Sarrigiannis PG,Artemiadis A,Skarlatou V,Hadjivassiliou M

更新日期：2021-01-13 00:00:00

abstract：:The purpose of this study was to investigate whether the previously demonstrated heterogeneity of myosin heavy chain (MHC) in type 2B fibers of the superficial portion of the lateral gastrocnemius (SLG) muscle of the rat may be due to presence of type 2D/X fibers. Immunohistochemical identification of MHC heterogeneit...

journal_title：Muscle & nerve

authors： Sawchak JA,Leung B,Shafiq SA

更新日期：1992-12-01 00:00:00

abstract：INTRODUCTION:Diagnosis of chronic inflammatory demyelinating polyneuropathy (CIDP) remains uncertain when nerve conduction studies (NCS) fail to show demyelination. METHODS:We conducted a retrospective study of patients who presented with clinical criteria of CIDP in whom electrodiagnostic (EDx) criteria of definite o...

journal_title：Muscle & nerve

authors： Devic P,Petiot P,Mauguiere F

更新日期：2016-01-01 00:00:00

abstract：:CNS conduction and autonomic nervous function were investigated in 15 patients with HMSN I. Central motor conduction time (CMCT) was estimated with magnetic brain stimulation and electrical nerve root stimulation. Somatosensory evoked potential (SEP) and visual evoked potential (VEP) were used for assessment of centra...

journal_title：Muscle & nerve

authors： Solders G,Andersson T,Persson A

更新日期：1991-11-01 00:00:00