Differential susceptibility of muscles to myotonia and force impairment in a mouse model of myotonic dystrophy.

abstract：:A review of our current knowledge of the etiology and pathogenesis of myasthenia gravis is presented, with particular emphasis on the immunological aspects of the disease. Part 1, published in the January/February issue of MUSCLE & NERVE, dealt with the clinical and genetic features of myasthenia gravis which led to t...

journal_title：Muscle & nerve

authors： Simpson JA

更新日期：1978-03-01 00:00:00

abstract：:To identify the underlying physiological mechanisms for the difference in the time to failure for two types of fatiguing contractions, 20 subjects performed force and position tasks with the elbow flexor muscles at a comparable net muscle torque for a similar duration. Prior to terminating each task, blood flow was oc...

journal_title：Muscle & nerve

authors： Rudroff T,Poston B,Shin IS,Bojsen-Møller J,Enoka RM

更新日期：2005-01-01 00:00:00

abstract：:We report three patients with inflammatory myopathy who presented clinically with weakness and wasting of only one limb. The myopathy progressed over 6 months and 5 years, respectively, in two patients and was stable after 8 years in the third patient. One patient had a skin rash. Serum CK was elevated in the two pati...

journal_title：Muscle & nerve

authors： Lederman RJ,Salanga VD,Wilbourn AJ,Hanson MR,Dudley AW Jr

更新日期：1984-02-01 00:00:00

abstract：:Patients (n = 41) with isolated weakness of the eyelids or extraocular muscles, who had been referred for single fiber electromyography (SFEMG), were followed up after 4 to 24 months, At follow-up the patients were classified as "definite ocular myasthenia gravis" (MG), "definite other diagnosis," or "no definite diag...

journal_title：Muscle & nerve

authors： Rouseev R,Ashby P,Basinski A,Sharpe JA

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Anti-cytosolic 5'-nucleotidase 1A (cN1A) antibodies are commonly detected in patients with sporadic inclusion body myositis (sIBM). However, their pathogenic role has not been established. Moreover, efforts toward identifying sIBM distinct clinicopathologic characteristics associated with these antibodies ha...

journal_title：Muscle & nerve

authors： Paul P,Liewluck T,Ernste FC,Mandrekar J,Milone M

更新日期：2020-12-29 00:00:00

abstract：:Patients with prior poliomyelitis may experience muscle function deterioration decades after onset of disease. The present study is aimed at describing electromyographic and morphometric evidence of muscular compensation and of on-going muscular instability. Ten subjects 42-62 years of age with onset of polio 25-52 ye...

journal_title：Muscle & nerve

authors： Einarsson G,Grimby G,Stålberg E

更新日期：1990-02-01 00:00:00

abstract：INTRODUCTION:Pretreatment with pyridostigmine bromide (PB) of human intercostal muscle fibers exposed to the irreversible acetylcholinesterase (AChE) inhibitor soman was investigated. METHODS:Muscles were pretreated with 3 × 10(-6) M PB or saline for 20 minutes, then exposed to 10(-7) M soman for 10 minutes. RESULTS:...

journal_title：Muscle & nerve

authors： Maselli RA,Henderson JD,Ng J,Follette D,Graves G,Wilson BW

更新日期：2011-04-01 00:00:00

abstract：INTRODUCTION:YouTube is an important resource for patients. No study has evaluated the information on peripheral neuropathy disseminated by YouTube videos. In this study, our aim was to perform a systematic review of information on YouTube regarding peripheral neuropathy. METHODS:The Web site (www.youtube.com) was sea...

journal_title：Muscle & nerve

authors： Gupta HV,Lee RW,Raina SK,Behrle BL,Hinduja A,Mittal MK

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to compare ultrasound echo intensity (EI) with high-resolution T1 -weighted MRI and to establish calibration equations to estimate percent intramuscular fat from EI. METHODS:Thirty-one participants underwent both ultrasound and MRI testing of 4 muscles: rectus femoris (RF); bicep...

journal_title：Muscle & nerve

authors： Young HJ,Jenkins NT,Zhao Q,Mccully KK

更新日期：2015-12-01 00:00:00

abstract：INTRODUCTION:Balance impairment contributes to gait dysfunction, falls, and reduced quality of life in adults with Charcot-Marie-Tooth disease (CMT) but has been minimally examined in pediatric CMT. METHODS:The CMT Pediatric Scale (CMTPedS) was administered to 520 children with CMT. Associations between balance functi...

journal_title：Muscle & nerve

authors： Estilow T,Glanzman AM,Burns J,Harrington A,Cornett K,Menezes MP,Shy R,Moroni I,Pagliano E,Pareyson D,Bhandari T,Muntoni F,Laurá M,Reilly MM,Finkel RS,Eichinger KJ,Herrmann DN,Troutman G,Bray P,Halaki M,Shy ME,Yu

更新日期：2019-09-01 00:00:00

abstract：:Infantile botulism is a recently recognized cause of acute hypotonic paresis and respiratory failure in young infants. Electrophysiological testing has proven useful in early diagnosis in suspected cases by demonstrating abnormal neuromuscular transmission as is known to occur in botulism. Twenty-five infants with bac...

journal_title：Muscle & nerve

authors： Cornblath DR,Sladky JT,Sumner AJ

更新日期：1983-07-01 00:00:00

abstract：:We examined and compared a mechanosensitive human sural neuroma and a contralateral sural nerve collected simultaneously from a patient involved in a diabetic neuropathy research protocol. Using indirect immunofluorescence staining. we identified a striking difference in the content within axons of two neuropeptides, ...

journal_title：Muscle & nerve

authors： Zochodne DW,Theriault M,Sharkey KA,Cheng C,Sutherland G

更新日期：1997-07-01 00:00:00

abstract：UNLABELLED:Contemporary natural history data in Duchenne muscular dystrophy (DMD) is needed to assess care recommendations and aid in planning future trials. METHODS:The Cooperative International Neuromuscular Research Group (CINRG) DMD Natural History Study (DMD-NHS) enrolled 340 individuals, aged 2-28 years, with DM...

journal_title：Muscle & nerve

authors： McDonald CM,Henricson EK,Abresch RT,Han JJ,Escolar DM,Florence JM,Duong T,Arrieta A,Clemens PR,Hoffman EP,Cnaan A,Cinrg Investigators.

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:The best treatment strategy for mild ulnar neuropathy at the elbow (UNE) is not known, due to lack of trials comparing surgery vs conservative treatment. METHODS:We recruited patients with clinical symptoms and signs of mild UNE and an electrophysiologically or sonographically confirmed diagnosis. Patient...

journal_title：Muscle & nerve

authors： Pompe SM,Schreuder T,Teunissen LL,Visser LH,Beekman R

更新日期：2020-08-01 00:00:00

abstract：:We report a patient with clinical vermiform motor activity, muscle cramps, delayed relaxation of grip, and continuous motor unit discharges who developed mild symmetric symptoms in the upper extremities following a viral infection. Treatment with carbamazepine produced considerable symptomatic improvement. Needle elec...

journal_title：Muscle & nerve

authors： Tandan R,Fries TJ

更新日期：1988-03-01 00:00:00

abstract：INTRODUCTION:We sought to determine whether electrical impedance myography (EIM) could serve as a diagnostic procedure for evaluation of radiculopathy. METHODS:Twenty-seven patients with clinically and radiologically diagnosed cervical or lumbosacral radiculopathy who met a "gold standard" definition underwent EIM and...

journal_title：Muscle & nerve

authors： Spieker AJ,Narayanaswami P,Fleming L,Keel JC,Muzin SC,Rutkove SB

更新日期：2013-11-01 00:00:00

abstract：INTRODUCTION:Spinal and bulbar muscular atrophy (SBMA) and amyotrophic lateral sclerosis (ALS) are motor neuron diseases. Sensory impairment is sometimes observed, and electrophysiological involvement has been described in the sensory nerves of SBMA patients. We hypothesized that a sensory nerve conduction study (NCS) ...

journal_title：Muscle & nerve

authors： Hama T,Hirayama M,Hara T,Nakamura T,Atsuta N,Banno H,Suzuki K,Katsuno M,Tanaka F,Sobue G

更新日期：2012-02-01 00:00:00

abstract：:The effect of endurance training on muscle electrical activity during general exercise testing was investigated in physically active patients with chronic obstructive pulmonary disease (COPD). Before and after rehabilitation, patients performed identical incremental exercise tests. Pulmonary gas exchange, venous lacta...

journal_title：Muscle & nerve

authors： Gosselin N,Lambert K,Poulain M,Martin A,Préfaut C,Varray A

更新日期：2003-12-01 00:00:00

abstract：INTRODUCTION:Repetitive loading of the low back tissues induces tension relaxation with a corresponding variation in the myoelectric response of the neuromuscular system, which may influence low back health. The purpose of this study was to observe trunk muscle activities before and after a passive cyclic trunk flexion...

journal_title：Muscle & nerve

authors： Olson MW

更新日期：2011-11-01 00:00:00

abstract：:The purpose of this study was to establish normal values of muscle thickness, ratio of muscle thickness to subcutaneous fat thickness, and muscle echo intensity in children between 11 weeks and 16 years of age. Transverse scans of four muscles were made by standardized real-time ultrasound examination. The scans were ...

journal_title：Muscle & nerve

authors： Scholten RR,Pillen S,Verrips A,Zwarts MJ

更新日期：2003-06-01 00:00:00

abstract：:Myasthenia gravis (MG) and its animal model experimental autoimmune myasthenia gravis (EAMG) are caused by autoantibodies against nicotinic acetylcholine receptor (AChR) in skeletal muscle. The production of anti-AChR antibodies is mediated by cytokines produced by CD4+ and CD8+ T helper (Th) cells. Emerging investiga...

journal_title：Muscle & nerve

authors： Zhang GX,Navikas V,Link H

更新日期：1997-05-01 00:00:00

abstract：:Two sisters presented with distal weakness and their muscle biopsy was dystrophic. This distal muscular dystrophy has an autosomal recessive inheritance and its features are somewhat different from the more common autosomal dominant distal muscular dystrophy and include: a) onset in early adult life; b) involvement of...

journal_title：Muscle & nerve

authors： Scoppetta C,Vaccario ML,Casali C,Di Trapani G,Mennuni G

更新日期：1984-07-01 00:00:00

abstract：INTRODUCTION:Chronic immune sensorimotor polyradiculopathy (CISMP) is a chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) variant affecting both sensory and motor nerve roots without evidence of peripheral nerve demyelination. METHODS:We report a case series of 9 patients with CISMP, identified from 2 t...

journal_title：Muscle & nerve

authors： Thammongkolchai T,Suhaib O,Termsarasab P,Li Y,Katirji B

更新日期：2019-06-01 00:00:00

abstract：:Muscle weakness in myasthenia gravis is due to autoantibody-induced loss of functional acetylcholine receptors (AChR). About 15% of myasthenia gravis patients, however, do not have detectable anti-AChR antibodies. To investigate the effect of their plasma immunoglobulins on neuromuscular transmission, mice were inject...

journal_title：Muscle & nerve

authors： Burges J,Vincent A,Molenaar PC,Newsom-Davis J,Peers C,Wray D

更新日期：1994-12-01 00:00:00

abstract：:We developed electrophysiologic methods for testing the three major forelimb nerves as a tool to evaluate motor and sensory recovery in rats. Median, ulnar, or radial nerves were transected and repaired in Sprague-Dawley rats. Compound muscle action potentials (CMAPs) and somatosensory evoked potentials (SSEPs) were r...

journal_title：Muscle & nerve

authors： Wang H,Sorenson EJ,Spinner RJ,Windebank AJ

更新日期：2008-10-01 00:00:00

abstract：INTRODUCTION:We sought to define the whole-body MRI (WB-MRI) fingerprint of muscle involvement in pediatric LMNA-related dystrophy (LMNA-RD) and to compare it with SEPN1-related myopathy (SEPN1-RM). METHODS:Signal abnormality and atrophy in 109 muscles were scored by semiquantitative scales in 8 children with LMNA-RD ...

journal_title：Muscle & nerve

authors： Gómez-Andrés D,Dabaj I,Mompoint D,Hankiewicz K,Azzi V,Ioos C,Romero NB,Ben Yaou R,Bergounioux J,Bonne G,Richard P,Estournet B,Yves-Carlier R,Quijano-Roy S

更新日期：2016-08-01 00:00:00

abstract：:Neuroinflammation is a characteristic of pathologically affected tissue in several neurodegenerative disorders. These changes can be observed in the brainstem and spinal cord of amyotrophic lateral sclerosis (ALS) cases and in mouse models of the disease. They include an accumulation of large numbers of activated micr...

journal_title：Muscle & nerve

authors： McGeer PL,McGeer EG

更新日期：2002-10-01 00:00:00

abstract：:A 62-year-old woman with axonal Guillain-Barré syndrome developed weakness and urinary retention simultaneously. The retention failed to recover for 10 months even after she regained the ability to walk. The patient exhibited no postural hypotension. Videourodynamics showed that the retention was caused not by the bla...

journal_title：Muscle & nerve

authors： Sakakibara R,Uchiyama T,Tamura N,Kuwabara S,Asahina M,Hattori T

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Widespread musculoskeletal pain is a well-known symptom of myotonic dystrophy type 2 (DM2), but so far it has been addressed in only a few studies. METHODS:A postal survey for all traceable DM2 patients (n = 132) was conducted. A specific questionnaire, and severity and interference subscales of the Brief...

journal_title：Muscle & nerve

authors： Suokas KI,Haanpää M,Kautiainen H,Udd B,Hietaharju AJ

更新日期：2012-01-01 00:00:00

abstract：:Type 1 diabetes mellitus (T1DM) is associated with a peripheral neuropathy that reduces nerve conduction velocity. This may impair high motor-unit discharge frequencies (MUDF), decrease muscle activation, and curtail the ability to sustain repetitive contractile tasks. We examined (1) whether MUDF, the contractile pro...

journal_title：Muscle & nerve

authors： Almeida S,Riddell MC,Cafarelli E

更新日期：2008-02-01 00:00:00