Measurement of intramuscular fat by muscle echo intensity.


INTRODUCTION:The aim of this study was to compare ultrasound echo intensity (EI) with high-resolution T1 -weighted MRI and to establish calibration equations to estimate percent intramuscular fat from EI. METHODS:Thirty-one participants underwent both ultrasound and MRI testing of 4 muscles: rectus femoris (RF); biceps femoris (BF); tibialis anterior (TA); and medial gastrocnemius (MG). RESULTS:Strong correlations were found between MRI percent fat and muscle EI after correcting for subcutaneous fat thickness (r = 0.91 in RF, r = 0.80 in BF, r = 0.80 in TA, r = 0.76 in MG). Three types of calibration equations were established. CONCLUSIONS:Muscle ultrasound is a practical and reproducible method that can be used as an imaging technique for examination of percent intramuscular fat. Future ultrasound studies are needed to establish equations for other muscle groups to enhance its use in both research and clinical settings.


Muscle Nerve


Muscle & nerve


Young HJ,Jenkins NT,Zhao Q,Mccully KK




Has Abstract


2015-12-01 00:00:00












  • Revised statistical motor unit number estimation in the Celecoxib/ALS trial.

    abstract::Techniques to estimate motor unit number (MUNE) measure the number of functioning motor units in a muscle. As amyotrophic lateral sclerosis (ALS) is characterized by progressive motor unit loss, this disease offers an ideal setting for the use of MUNE. Statistical MUNE was employed in a recent multicenter trial of cre...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Shefner JM,Cudkowicz ME,Zhang H,Schoenfeld D,Jillapalli D,Northeast ALS Consortium.

    更新日期:2007-02-01 00:00:00

  • Ethical review of research involving human subjects: when and why is IRB review necessary?

    abstract::Requirements for ethical review of research involving human subjects are based on widely accepted international standards that are implemented by various national regulations and institutional policies. In the United States, most human research is reviewed by institutional review boards (IRBs) applying federal standar...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Wagner RM

    更新日期:2003-07-01 00:00:00

  • Ethical issues in the evaluation of adults with suspected genetic neuromuscular disorders.

    abstract::Genetic testing is rapidly becoming an increasingly significant part of the diagnostic armamentarium of neuromuscular clinicians. Although technically easy to order, the results of such testing, whether positive or negative, have potentially enormous consequences for the individual tested and for family members. As a ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Su X,Kang PB,Russell JA,Simmons Z

    更新日期:2016-12-01 00:00:00

  • Foot measures in patients with pes cavus with and without charcot-marie-tooth disease: A pilot study.

    abstract:INTRODUCTION:Pes cavus often signals the presence of Charcot-Marie-Tooth (CMT) in adult patients, although its prevalence in the general population makes it a finding of unclear significance. METHODS:We undertook a pilot double cohort study to investigate the feasibility of comparing preselected bedside and radiograph...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Stino AM,Atway S,Anthony M,Kline D,Kissel JT

    更新日期:2019-01-01 00:00:00

  • Analysis of muscle fiber clustering in the diaphragm muscle of sarcopenic mice.

    abstract:INTRODUCTION:Sarcopenia likely comprises muscle fiber denervation and re-innervation, resulting in clustering of muscle fibers of the same type (classified by myosin heavy chain isoform composition). Development of methodology to quantitatively evaluate clustering of muscle fibers according to fiber type is necessary. ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Greising SM,Medina-Martínez JS,Vasdev AK,Sieck GC,Mantilla CB

    更新日期:2015-07-01 00:00:00

  • Somatosensory evoked potentials following stimulation of digital nerves.

    abstract::Cortical and spinal somatosensory evoked potentials (SEP) were recorded in healthy individuals following stimulation of digits I, III, and V with an intensity below discomfort level. Peak latency of the earliest cortical negativity (N1) was found to be the most consistent and easily measured parameter, whereas a spina...

    journal_title:Muscle & nerve

    pub_type: 临床试验,杂志文章


    authors: Kwast-Rabben O,Libelius R,Heikkilä H

    更新日期:2002-10-01 00:00:00

  • Hypothyroid myopathy with a strikingly elevated serum creatine kinase level.

    abstract::Although serum creatine kinase (CK) levels are frequently modestly elevated in patients with hypothyroid myopathy, elevations in serum CK to the levels usually seen in inflammatory myopathies or dystrophies are rare. We report a patient with progressive proximal weakness and a serum CK level of over 29,000 IU/L, in wh...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Scott KR,Simmons Z,Boyer PJ

    更新日期:2002-07-01 00:00:00

  • Neurologic complications after surgery for obesity.

    abstract::Bariatric surgical procedures are increasingly common. In this review, we characterize the neurologic complications of such procedures, including their mechanisms, frequency, and prognosis. Literature review yielded 50 case reports of 96 patients with neurologic symptoms after bariatric procedures. The most common pre...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Koffman BM,Greenfield LJ,Ali II,Pirzada NA

    更新日期:2006-02-01 00:00:00

  • Risk of thrombotic events after inpatient intravenous immunoglobulin or plasma exchange for neurologic disease: A case-crossover study.

    abstract:INTRODUCTION:Our aim in this study was to determine whether intravenous immunoglobulin (IVIg) or plasma exchange (PLEx) for treatment of neurologic disease is a trigger for thrombotic events. METHODS:Using administrative data from 2005 to 2014, we identified index admissions for thrombotic events. We performed case-cr...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Jin PH,Shin SC,Dhamoon MS

    更新日期:2020-09-01 00:00:00

  • Interaction of thyroid state and denervation on skeletal myosin heavy chain expression.

    abstract::The goal of this study was to examine the effects of altered thyroid state and denervation (Den) on skeletal myosin heavy chain (MHC) expression in the plantaris and soleus muscles. Rats were subjected to unilateral denervation (Den) and randomly assigned to one of three groups: (1) euthyroid; (2) hyperthyroid; (3) an...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Haddad F,Arnold C,Zeng M,Baldwin K

    更新日期:1997-12-01 00:00:00

  • Detection of hereditary neuropathy with liability to pressure palsies among patients with acute painless mononeuropathy or plexopathy.

    abstract::Hereditary neuropathy with liability to pressure palsies (HNPP) is an autosomal dominant disorder characterized by recurrent mononeuropathies or brachial plexopathies, commonly associated with a chromosome 17p11.2-12 deletion encompassing the peripheral myelin protein-22 (PMP22) gene. We tried to identify criteria dis...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Pareyson D,Solari A,Taroni F,Botti S,Fallica E,Scaioli V,Ciano C,Sghirlanzoni A

    更新日期:1998-12-01 00:00:00

  • Different contribution of joint and cutaneous inputs to early scalp somatosensory evoked potentials.

    abstract::To elucidate whether the frontal components of scalp somatosensory evoked potentials (SEPs) depend on the type of peripheral input, we compared scalp SEPs in response to electrical stimuli applied to: (i) the proximal phalanx of the thumb, involving both deep and cutaneous afferents; and (ii) the distal phalanx of the...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Restuccia D,Valeriani M,Barba C,Le Pera D,Tonali P,Mauguière F

    更新日期:1999-07-01 00:00:00

  • Posterior femoral cutaneous neuralgia.

    abstract::A middle-aged male developed a right posterior femoral cutaneous neuralgia that persisted for 10 years without any associated neurologic, electrophysiologic, or radiologic findings. Five years after onset, surgical exploration of the subgluteal area identified a venous malformation surrounding the nerve. The syndrome ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Chutkow JG

    更新日期:1988-11-01 00:00:00

  • Intravascular lymphomatosis.

    abstract::Intravascular lymphomatosis, also known as endovascular lymphoma or angiotropic large cell lymphoma, is a rare malignancy typically diagnosed at autopsy. We describe a case in which the diagnosis was made at an early stage. Specific electrodiagnostic findings suggested concomitant polyneuropathy and myopathy. Suspicio...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Oei ME,Kraft GH,Sarnat HB

    更新日期:2002-05-01 00:00:00

  • Congenital myasthenic syndromes: progress over the past decade.

    abstract::Congenital myasthenic syndromes (CMS) stem from defects in presynaptic, synaptic basal lamina, and postsynaptic proteins. The presynaptic CMS are associated with defects that curtail the evoked release of acetylcholine (ACh) quanta or ACh resynthesis. Defects in ACh resynthesis have now been traced to mutations in cho...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Engel AG,Ohno K,Sine SM

    更新日期:2003-01-01 00:00:00

  • The care of patients with Duchenne, Becker, and other muscular dystrophies in the COVID-19 pandemic.

    abstract::The coronavirus disease 2019 (COVID-19) pandemic has resulted in the reorganization of health-care settings affecting clinical care delivery to patients with Duchenne and Becker muscular dystrophy (DBMD) as well as other inherited muscular dystrophies. The magnitude of the impact of this public health emergency on the...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Veerapandiyan A,Wagner KR,Apkon S,McDonald CM,Mathews KD,Parsons JA,Wong BL,Eichinger K,Shieh PB,Butterfield RJ,Rao VK,Smith EC,Proud CM,Connolly AM,Ciafaloni E

    更新日期:2020-07-01 00:00:00

  • Time course of axonal regeneration in acute motor axonal neuropathy.

    abstract::Patients with acute motor axonal neuropathy (AMAN) generally recover well. We reviewed clinical and electrophysiologic recovery in 13 patients for up to 5 years. Twelve patients showed rapid recovery over 12 months, whereas in the remaining one the recovery was slow and incomplete at 5 years. In AMAN, axonal degenerat...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Tamura N,Kuwabara S,Misawa S,Kanai K,Nakata M,Sawai S,Mori M,Hattori T

    更新日期:2007-06-01 00:00:00

  • Charcot-Marie-Tooth disease with intermediate conduction velocities caused by a novel mutation in the MPZ gene.

    abstract::Charcot-Marie-Tooth (CMT) disease is a heterogeneous group of inherited sensory and motor neuropathies. Mutations in the gene that encodes for myelin protein zero (MPZ) can produce different phenotypes: CMT1 (with low conduction velocities), CMT2 (less frequent and with unaffected conduction velocities), and CMTID (wi...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Banchs I,Casasnovas C,Montero J,Volpini V,Martínez-Matos JA

    更新日期:2010-08-01 00:00:00

  • Early changes of muscle insulin-like growth factor-1 and myostatin gene expression in gastric cancer patients.

    abstract:INTRODUCTION:Cachexia increases morbidity and mortality of cancer patients. The progressive loss of muscle mass negatively affects physical function and quality of life. We previously showed reduced muscle insulin-like growth factor-1 (IGF-1) expression and enhanced myostatin signaling in tumor-bearing animals. This st...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Bonetto A,Penna F,Aversa Z,Mercantini P,Baccino FM,Costelli P,Ziparo V,Lucia S,Rossi Fanelli F,Muscaritoli M

    更新日期:2013-09-01 00:00:00

  • AAEE case report #18: Ulnar neuropathy in the distal forearm.

    abstract::A 66-year-old professional golf instructor developed pain, numbness, and weakness in an ulnar distribution, but the lesion could not be localized to either elbow or wrist by routine nerve conduction techniques. Stimulation along serial 1-cm increments in the distal forearm disclosed a point of focal conduction block a...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Campbell WW

    更新日期:1989-05-01 00:00:00

  • Did giant mitochondria delay muscle maturation? An uncommon congenital myopathy.

    abstract:INTRODUCTION:Mitochondria are semi-autonomous organelles that are able to change their shape, size, location, and number inside the living cell. Mitochondrial division is an extremely important process, because cell survival depends on there being an adequate number of mitochondria in each cell. The dynamics of these o...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Fidziańska A,Glinka Z

    更新日期:2012-07-01 00:00:00

  • Peripheral nerve size in normals and patients with polyneuropathy: an ultrasound study.

    abstract::Ultrasound has been used for visualizing peripheral nerve pathology. Our goal was to use ultrasound to quantitate the sizes of upper extremity nerves along their length in control subjects and patients with neuropathy. We measured median and ulnar nerve cross-sectional areas (NCSA) in the arms of 190 subjects, includi...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Zaidman CM,Al-Lozi M,Pestronk A

    更新日期:2009-12-01 00:00:00

  • Temperature dependence of contraction characteristics in developing rat muscles.

    abstract::Contractions of rat extensor digitorum longus (EDL, a fast muscle) and soleus (SOL, a slow muscle) muscles of different ages (1-4 weeks) were recorded in vitro with direct stimulation and at different temperatures (range 35-10 degrees C). Twitch tension in 4-week-old EDL muscle increased in cooling from 35 to 20 degre...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Wylie SR,Ranatunga KW

    更新日期:1987-11-01 00:00:00

  • Role of nerve and tension in maturation of posthatching slow-tonic muscle in chicken.

    abstract::The role of motor innervation and muscle tension in the posthatching maturation of the slow-tonic anterior latissimus dorsi (ALD) muscle of the chicken has been investigated. Modification of the muscle tension was obtained either by maintaining ALD in a shortened state or by stretching, after or without denervation. I...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Gardahaut MF,Rouaud TP,Renaud D,Khaskiye A,Le Douarin GH

    更新日期:1989-11-01 00:00:00

  • Chronic bilateral T1 denervation in women with macromastia.

    abstract:INTRODUCTION:The objective of this study was to identify the pattern of neurological deficits and document electrophysiological changes in women with macromastia. METHODS:Patients with macromastia and neurological complaints underwent clinical evaluation and electrodiagnostic (EDx) studies of the upper limbs. RESULTS...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Ansell JR,Buchholz MC

    更新日期:2013-02-01 00:00:00

  • Widespread tissue distribution of multiple mitochondrial DNA deletions in familial mitochondrial myopathy.

    abstract::We used Southern blot analysis and the polymerase chain reaction to analyze the tissue distribution of multiple mitochondrial DNA (mtDNA) deletions in a 45-year-old man with familial mitochondrial myopathy-Southern blots showed two major types of abnormal mtDNA with approximately 4- and 8-kilobase deletions in the ske...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Kawashima S,Ohta S,Kagawa Y,Yoshida M,Nishizawa M

    更新日期:1994-07-01 00:00:00

  • Peripheral nervous system involvement in chronic spinal cord injury.

    abstract:INTRODUCTION:Upper motor neuron disorders are believed to leave the peripheral nervous system (PNS) intact. In this study we examined whether there is evidence of PNS involvement in spinal cord injury (SCI). METHODS:Twelve subjects with chronic low cervical or thoracic SCI were included prospectively. Needle electromy...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Tankisi H,Pugdahl K,Rasmussen MM,Clemmensen D,Rawashdeh YF,Christensen P,Krogh K,Fuglsang-Frederiksen A

    更新日期:2015-12-01 00:00:00

  • Central nervous system involvement in multifocal demyelinating neuropathy with persistent conduction block.

    abstract::We report the case of a 27-year-old man treated for bilateral optic neuritis 5 and 3 years before who within a few months developed sensorimotor disorders of the arms and legs characterized by asymmetric distribution and distal prominence. In addition to sensorimotor defects, which were particularly marked in the left...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Péréon Y,Jardel J,Guillon B,Guihéneuc P

    更新日期:1994-11-01 00:00:00

  • Surgery for peripheral nerve and brachial plexus injuries or other nerve lesions.

    abstract::The selection of patients who will benefit from peripheral nerve surgery continues to evolve. The evaluation of patients with peripheral nerve problems, and the indications and timing of surgery are reviewed. This includes patients with transections, lesions in continuity, entrapments, tumors, injection injuries, and ...

    journal_title:Muscle & nerve

    pub_type: 杂志文章,评审


    authors: Spinner RJ,Kline DG

    更新日期:2000-05-01 00:00:00

  • CK-MM autoantibodies: prevalence, immune complexes, and effect on CK clearance.

    abstract::Although the blood level of creatine kinase (CK) is the most commonly used marker of muscle injury, there is marked interindividual variability in this measure. Part of this variability may be attributed to variability in the rate of CK clearance from the circulation. In this study, we assessed the possibility that CK...

    journal_title:Muscle & nerve

    pub_type: 杂志文章


    authors: Warren GL,O'farrell L,Rogers KR,Billings KM,Sayers SP,Clarkson PM

    更新日期:2006-09-01 00:00:00