Abstract:
:The loss of muscle strength with aging appears to be greater in the lower than upper limbs, but strength and its neural control have never been compared in the same population of individuals in both upper and lower limbs. The aim of this study was to investigate differences between eight young (20-31 years) and eight older (68-76 years) healthy women in maximal voluntary contraction (MVC), force fluctuations, median frequency (MDF) of the surface electromyogram (sEMG), and muscle fiber conduction velocity (MFCV) during sustained isometric elbow flexion (EF) and knee extension (KE), performed at moderate to high force intensity. Older women showed larger fluctuations of force with endurance and changes in sEMG pointing to less fatigue, especially at high level of force, with no differences between upper and lower extremities. This may have significant implications in the design of rehabilitation programs directed to this population.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Bazzucchi I,Felici F,Macaluso A,De Vito Gdoi
10.1002/mus.20151subject
Has Abstractpub_date
2004-11-01 00:00:00pages
626-35issue
5eissn
0148-639Xissn
1097-4598journal_volume
30pub_type
杂志文章相关文献
MUSCLE & NERVE文献大全abstract::Genetically homozygous line 413 dystrophic chickens were given twice-daily intraperitoneal injections of solutions containing branched-chain amino acids (BCCA-leucine, valine, isoleucine) either alone or in combination; and their alpha-ketoacid analogs (alpha-ketoisocaproic and alpha-ketoisovaleric acids). Another tri...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880050606
更新日期:1982-07-01 00:00:00
abstract::A small-scale procedure for preparing tightly coupled intact skeletal muscle mitochondria from myodystrophic (myd/myd) mice is described. Mitochondrial preparations derived from heart, liver, and skeletal muscle of myd/myd and their littermate (+/?) controls are characterized with respect to their cytochrome content a...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880020504
更新日期:1979-09-01 00:00:00
abstract::To obtain normative muscle morphology data on a healthy population recruited from a population survey, we examined vastus lateralis biopsies from 58 men and 33 women, aged 26-67 years. Biopsies were measured with automated, computer-aided techniques. Data were analyzed according to gender and age, and the influence of...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/mus.10373
更新日期:2003-07-01 00:00:00
abstract::A link between the cardioprotective benefits of pharmacological preconditioning and natural mammalian hibernation is considered to involve the cellular activation of opioid receptors and subsequent opening of K(ATP) channels. In previous studies, we have demonstrated the protective effects of specific delta-opioid ago...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20354
更新日期:2005-08-01 00:00:00
abstract:INTRODUCTION:Skeletal muscle oxidative capacity decreases and fatigability increases after spinal cord injury. Transcription factor peroxisome proliferator-activated receptor δ (PPARδ) promotes a more oxidative phenotype. METHODS:We asked whether PPARδ overexpression could ameliorate these deficits in the medial gastr...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24723
更新日期:2016-02-01 00:00:00
abstract::The synthesized pyrimidine compound MS-818 has neurotrophic effects in several kinds of neuronal cells, but its effect with respect to muscle cells remains unknown. We therefore examined the effects of MS-818 on regeneration for 12 weeks in a wounded area (damaged and gap areas) of cut muscle in adult rats. The right ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10028
更新日期:2002-02-01 00:00:00
abstract::The purpose of this study was to investigate whether the previously demonstrated heterogeneity of myosin heavy chain (MHC) in type 2B fibers of the superficial portion of the lateral gastrocnemius (SLG) muscle of the rat may be due to presence of type 2D/X fibers. Immunohistochemical identification of MHC heterogeneit...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880151210
更新日期:1992-12-01 00:00:00
abstract::Peripheral nerve disorders are commonly encountered in clinical practice. Electrodiagnostic studies remain the cornerstone of the evaluation of nerve disorders. More recently, ultrasound has played an increasing complementary role in the neuromuscular clinic. Ultrasound elastography is a technique that measures the el...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26624
更新日期:2019-11-01 00:00:00
abstract::We studied histopathological changes in the biceps brachii muscle in relation to age and the degree of muscle weakness in 64 patients (aged 11-59 years) with myotonic dystrophy. The proportion of type 1 fibers was unaltered in the adolescent patients compared with control values, but increased with age. The average di...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880170911
更新日期:1994-09-01 00:00:00
abstract::Danon disease is a rare X-linked dominant disorder caused by lysosomal-associated membrane protein 2 (LAMP2) deficiency and is characterized by hypertrophic cardiomyopathy, cardiac conduction abnormalities, skeletal vacuolar myopathy, variable degree of mental retardation, and peripheral pigmentary retinopathy. We des...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20930
更新日期:2008-03-01 00:00:00
abstract::In anterior interosseous nerve syndrome and ulnar neuropathy, paralysis or weakness of the flexor digitorum profundus (FDP) muscles has been shown to vary according to the degree of involvement of the median and ulnar nerves, respectively. We traced these nerves in 50 cadaveric specimens in which each FDP was complete...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21281
更新日期:2009-04-01 00:00:00
abstract::Muscle weakness in myasthenia gravis is due to autoantibody-induced loss of functional acetylcholine receptors (AChR). About 15% of myasthenia gravis patients, however, do not have detectable anti-AChR antibodies. To investigate the effect of their plasma immunoglobulins on neuromuscular transmission, mice were inject...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880171208
更新日期:1994-12-01 00:00:00
abstract::Intravascular lymphomatosis, also known as endovascular lymphoma or angiotropic large cell lymphoma, is a rare malignancy typically diagnosed at autopsy. We describe a case in which the diagnosis was made at an early stage. Specific electrodiagnostic findings suggested concomitant polyneuropathy and myopathy. Suspicio...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10091
更新日期:2002-05-01 00:00:00
abstract::Large muscle genes are often sequenced using complementary DNA (cDNA) made from muscle messenger RNA (mRNA) to reduce the cost and workload associated with sequencing from genomic DNA. Two potential barriers are the availability of a frozen muscle biopsy, and difficulties in detecting nonsense mutations due to nonsens...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.22118
更新日期:2011-08-01 00:00:00
abstract::Electrophysiologic detection of the first signs of gastrocnemius muscle reinnervation shows that after a single localized freezing of the rat sciatic nerve, isaxonine does not significantly increase the rate of axonal regeneration. However, this drug does significantly enhance axonal sprouting, as it induces an increa...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880080205
更新日期:1985-02-01 00:00:00
abstract:INTRODUCTION:The probability and degree of muscle recovery after lesions of long peripheral nerves have not been assessed quantitatively. METHODS:Twelve adults with closed injuries of the fibular division of the sciatic nerve with complete denervation of associated muscles were followed-up for 2-10 years. The onset of...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25103
更新日期:2016-10-01 00:00:00
abstract::Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disorder characterized by autoantibodies against presynaptic voltage-gated calcium channels that impair neuromuscular transmission. Malignancies, especially small cell lung cancer (SCLC), have been associated with LEMS and account for approximately 60% of cases...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24122
更新日期:2014-03-01 00:00:00
abstract::Focal entrapment of the ulnar nerve occurs most frequently in the region of the elbow, at the ulnar groove or beneath the humeroulnar aponeurosis. Surgical treatment commonly involves transposition of the nerve anterior to the medial epicondyle, in the antecubital fossa. Symptoms may recur after surgery, and, to asses...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20103
更新日期:2004-10-01 00:00:00
abstract::Myasthenia gravis (MG) and its animal model experimental autoimmune myasthenia gravis (EAMG) are caused by autoantibodies against nicotinic acetylcholine receptor (AChR) in skeletal muscle. The production of anti-AChR antibodies is mediated by cytokines produced by CD4+ and CD8+ T helper (Th) cells. Emerging investiga...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199705)20:5<543::aid-mus2>
更新日期:1997-05-01 00:00:00
abstract::Skeletal muscle fibers from dystrophic mice and littermate controls (ReJ-129) were characterized electrically and then injected with an intracellular marker. In this way they could be identified for examination with an electron microscope to correlate the relative time course of electrical and ultrastructural alterati...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880060104
更新日期:1983-01-01 00:00:00
abstract::The electrical and mechanical properties of paralyzed human thenar muscles were measured in response to supramaximal stimulation of the median nerve in individuals with chronic cervical spinal cord injury. These data were compared to those recorded from control muscles. Spontaneous motor unit activity was common in pa...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199707)20:7<788::aid-mus2>
更新日期:1997-07-01 00:00:00
abstract::Type 1 myotonic dystrophy or DM1 (Steinert's disease), which is the commonest muscular dystrophy in adults, has intrigued physicians for over a century. Unusual features, compared with other dystrophies, include myotonia, anticipation, and involvement of other organs, notably the brain, eyes, smooth muscle, cardiac co...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.20301
更新日期:2005-07-01 00:00:00
abstract::To determine the contributions of neural and mechanical mechanisms to the limits in the range of motion (ROM) about a joint, we studied the effects of 30 sessions of static stretch training on the characteristics of the plantar-flexor muscles in 12 subjects. Changes in the maximal ankle dorsiflexion and the torque pro...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10549
更新日期:2004-02-01 00:00:00
abstract::Guillain-Barré syndrome (GBS) is an inflammatory polyradiculoneuropathy associated with numerous viral infections. Recently, there have been many case reports describing the association between coronavirus disease-2019 (COVID-19) and GBS, but much remains unknown about the strength of the association and the features ...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.27024
更新日期:2020-10-01 00:00:00
abstract::High-dose immunoglobulins for intravenous administration (IVIg) have originally been developed for substitution therapy in hypogammaglobulinemia. Over the last decade they are increasingly used in the treatment of immune-mediated diseases. In this review the results in immune-mediated neuromuscular diseases are summar...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-4598(199702)20:2<136::aid-mus1>
更新日期:1997-02-01 00:00:00
abstract::Comparison was made between simultaneous recordings of the electromyogram (EMG) and acoustic myogram (AMG) signals and the torque produced by the lumbar erectores spinae muscles of three healthy subjects while they performed isometric contractions. Repeatability of each signal was studied. The AMG had a relationship t...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880110409
更新日期:1988-04-01 00:00:00
abstract::Loss of cells from the motor system occurs during the normal aging process, leading to reduction in the complement of motor neurons and muscle fibers. The latter age-related decrease in muscle mass has been termed "sarcopenia" and is often combined with the detrimental effects of a sedentary lifestyle in older adults,...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.1215
更新日期:2002-01-01 00:00:00
abstract::A stand-alone ultrasound shear wave imaging technology has been developed to quantify and visualize Young's modulus distribution by remotely applying ultrasound radiation force and tracking the resulting microvibrations in soft tissues with ultrafast ultrasound imaging. We report the first preliminary data that detect...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21723
更新日期:2010-09-01 00:00:00
abstract:INTRODUCTION:Previous studies have reported higher wrist ratios (WR) related to carpal tunnel syndrome (CTS) but have not assessed effect modification by obesity and may have inadequately controlled for confounders. METHODS:Baseline data of a multicenter prospective cohort study were analyzed. CTS was defined by nerve...
journal_title:Muscle & nerve
pub_type: 杂志文章,多中心研究
doi:10.1002/mus.25692
更新日期:2017-12-01 00:00:00
abstract::Multifocal motor neuropathy (MMN) is a chronic, immune-mediate, peripheral myelinopathy. Inherent in its name, MMN implies involvement of two or more motor nerves. We report three patients with weakness and partial motor conduction block restricted to a single nerve and localized to sites that are not at risk for entr...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10088
更新日期:2002-05-01 00:00:00