Skeletal muscle ultrastructure and function in statin-tolerant individuals.

abstract：INTRODUCTION:Topical application of lidocaine-and-prilocaine (LP) cream attenuates the functionality of small cutaneous nerve fibers. The aim of this human study was to measure the underlying excitability modulation of small cutaneous nerve fibers using a novel and fast perception threshold tracking (PTT) technique. M...

journal_title：Muscle & nerve

authors： Nielson Hoberg T,Frahm S,Hennings K,Arendt-Nielsen L,Dahl Mørch C

更新日期：2019-10-01 00:00:00

abstract：:Biochemical, morphologic, and biophysical studies support the concept that the red blood cell (RBC) membrane is altered in both myotonic muscular dystrophy (MyD) and Duchenne muscular dystrophy (DMD). These studies have not identified a primary metabolic defect that would explain the various alterations of membrane pr...

journal_title：Muscle & nerve

authors： Plishker GA,Appel SH

更新日期：1980-01-01 00:00:00

abstract：INTRODUCTION:Ulnar nerve displacement at the elbow causes overestimation of nerve conduction velocity. We hypothesized that this overestimation may cause false-negative results when the American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) diagnostic criteria are used. METHODS:We investigated 9 ...

journal_title：Muscle & nerve

authors： Won SJ,Yoon JS,Kim JY,Kim SJ,Jeong JS

更新日期：2011-10-01 00:00:00

abstract：:Weakness is common in both hyper- and hypothyroidism, and skeletal muscle L-carnitine may play a role in this regard, as suggested by studies indicating abnormal levels of carnitine in serum and urine of patients with thyroid dysfunction. Skeletal muscle samples were obtained for carnitine analysis from control subjec...

journal_title：Muscle & nerve

authors： Sinclair C,Gilchrist JM,Hennessey JV,Kandula M

更新日期：2005-09-01 00:00:00

abstract：INTRODUCTION:C8-root impingement by C7/T1 lesions on neuroimaging studies is not consistently observed in C8 radiculopathy. We hypothesized that C7 or T1 root lesions (with a pre- or postfixed plexus) or cervical myelopathy might explain some "C8 radiculopathies" without C8 root compression. METHODS:Retrospective anal...

journal_title：Muscle & nerve

authors： Hehir MK,Figueroa JJ,Zynda-Weiss AM,Stanton M,Logigian EL

更新日期：2012-06-01 00:00:00

abstract：:On magnetic resonance (MR) imaging of the brachial plexus increased signal intensity and swelling of the brachial plexus has been found in chronic inflammatory demyelinating polyneuropathy (CIDP). Whether these proximal abnormalities are also present in the distal polyneuropathy associated with monoclonal gammopathy i...

journal_title：Muscle & nerve

authors： Eurelings M,Notermans NC,Franssen H,Van Es HW,Ramos LM,Wokke JH,van den Berg LH

更新日期：2001-10-01 00:00:00

abstract：:The authors reported a large study of 93 children presenting a severe form of progressive muscular dystrophy. The first clinical symptoms were noticed between 3 to 12 years. The atrophy affects, predominantly, the girdle and truncal muscles. The hypertrophy of the calves is almost consistent. The progression of the di...

journal_title：Muscle & nerve

authors： Ben Hamida M,Fardeau M,Attia N

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:This was a multicenter, double-blind, randomized clinical trial to investigate the efficacy of electrical stimulation of denervated muscle (ESDM) on recovery of patients with peripheral nerve injuries. METHODS:We enrolled 38 patients with traumatic peripheral nerve injuries with axonal damage and clinical i...

journal_title：Muscle & nerve

authors： Piccinini G,Cuccagna C,Caliandro P,Coraci D,Germanotta M,Pecchioli C,Padua L

更新日期：2020-06-01 00:00:00

abstract：:We report on five patients who presented with unilateral or bilateral hypoplasia of the thenar eminence. X rays of the affected limbs showed varying degrees of malformation and underdevelopment of the thumb phalanges and first metacarpal bone, and of the carpal bones at the base of the thumb, indicating a developmenta...

journal_title：Muscle & nerve

authors： Cavanagh NP,Yates DA,Sutcliffe J

更新日期：1979-11-01 00:00:00

abstract：INTRODUCTION:Widespread musculoskeletal pain is a well-known symptom of myotonic dystrophy type 2 (DM2), but so far it has been addressed in only a few studies. METHODS:A postal survey for all traceable DM2 patients (n = 132) was conducted. A specific questionnaire, and severity and interference subscales of the Brief...

journal_title：Muscle & nerve

authors： Suokas KI,Haanpää M,Kautiainen H,Udd B,Hietaharju AJ

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Breast cancer is exceptionally associated with anti-collapsin response mediator protein 5 (anti-CRMP5) antibody or demyelinating neuropathy. This paraneoplastic antibody is itself not associated with demyelinating neuropathy. METHODS:Herein we describe a patient with a predominantly sensory ataxic demyeli...

journal_title：Muscle & nerve

authors： Samarasekera S,Rajabally YA

更新日期：2011-05-01 00:00:00

abstract：:Cultured human skin fibroblasts from 9 patients with Duchenne muscular dystrophy (DMD) and 8 normal age- and sex-matched controls were examined for creatine kinase (CK) activity. Both the normal and the DMD fibroblasts were found to have significant levels of CK activity (approximately 10 x 10(-3) IU per milligram of ...

journal_title：Muscle & nerve

authors： Davis MH,Cappel R,Vester JW,Samaha FJ,Gruenstein E

更新日期：1982-01-01 00:00:00

abstract：:Epidemiological data suggest that prolonged exposure to cyclic lumbar flexion elicits a chronic neuromuscular disorder and disability in workers. This study provides a physiological and biomechanical assessment of various repetitions of cyclic lumbar flexion sessions as a risk factor for development of an acute neurom...

journal_title：Muscle & nerve

authors： Navar D,Zhou BH,Lu Y,Solomonow M

更新日期：2006-11-01 00:00:00

abstract：:The purpose of this long-term, open parallel-group, double-consent study of alternate-day, low-dose prednisone in 2-4-year-old patients with Duchenne muscular dystrophy (DMD) was to determine whether prednisone produces a beneficial effect when given earlier than usual. Muscle function was evaluated by timed tests, an...

journal_title：Muscle & nerve

authors： Merlini L,Cicognani A,Malaspina E,Gennari M,Gnudi S,Talim B,Franzoni E

更新日期：2003-02-01 00:00:00

abstract：INTRODUCTION:In preparation for clinical trials we examine the validity, reliability, and patient understanding of the Myotonic Dystrophy Health Index (MDHI). METHODS:Initially we partnered with 278 myotonic dystrophy type-1 (DM1) patients and identified the most relevant questions for the MDHI. Next, we used factor a...

journal_title：Muscle & nerve

authors： Heatwole C,Bode R,Johnson N,Dekdebrun J,Dilek N,Heatwole M,Hilbert JE,Luebbe E,Martens W,Mcdermott MP,Rothrock N,Thornton C,Vickrey BG,Victorson D,Moxley R 3rd

更新日期：2014-06-01 00:00:00

abstract：:The spectrum of neuromuscular disorders among intensive care unit (ICU) patients has shifted toward disorders acquired within the ICU and away from "traditional" neuromuscular disorders that lead to ICU admission. We sought to assess this spectrum by determining the causes and relative frequencies of neuromuscular dis...

journal_title：Muscle & nerve

authors： Lacomis D,Petrella JT,Giuliani MJ

更新日期：1998-05-01 00:00:00

abstract：:The pattern of an abnormal median-normal sural (AMNS) sensory response is associated with acute and chronic inflammatory demyelinating polyradiculoneuropathy (AIDP and CIDP) and considered unusual in other types of neuropathy, although specificity and sensitivity of this pattern have not been evaluated. We compared se...

journal_title：Muscle & nerve

authors： Bromberg MB,Albers JW

更新日期：1993-03-01 00:00:00

abstract：INTRODUCTION:This case report focuses on identifying novel mutations in juvenile motor neuron disease and emphasizes the significance of whole exome sequencing (WES). METHODS:We report a 13-year-old Hispanic boy with rapidly progressive weakness, muscle atrophy, tremor, and tongue fasciculation, along with upper motor...

journal_title：Muscle & nerve

authors： Agarwal S,Potocki L,Collier TR,Woodbury SL,Adesina AM,Jones J,Lotze TE

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION:This study was designed to assess the effect of extracorporeal shock-wave lithotripsy (ESWL) exposure of the parotid gland on oxidative stress and some trace element levels in the facial nerves of rats. METHODS:Twelve male Wistar albino rats were divided into two groups, each consisting of 6 animals. The ...

journal_title：Muscle & nerve

authors： Kavak S,Garca MF,Gecit I,Meral I,Cengiz N,Demir H

更新日期：2012-04-01 00:00:00

abstract：INTRODUCTION:The current practice of single-fiber electromyography (SFEMG) requires that 20 fiber pairs with normal jitter be collected to exclude myasthenia gravis (MG). We applied principles of futility analysis from clinical trials in an attempt to reduce that requirement. METHODS:We utilized conditional power futi...

journal_title：Muscle & nerve

authors： Narayanaswami P,Pantoja-Galicia N,Betensky RA,Rutkove SB

更新日期：2012-04-01 00:00:00

abstract：:Neuroinflammation is a characteristic of pathologically affected tissue in several neurodegenerative disorders. These changes can be observed in the brainstem and spinal cord of amyotrophic lateral sclerosis (ALS) cases and in mouse models of the disease. They include an accumulation of large numbers of activated micr...

journal_title：Muscle & nerve

authors： McGeer PL,McGeer EG

更新日期：2002-10-01 00:00:00

abstract：:This study was designed to compare electromyogram (EMG) and acoustic myogram (AMG) recordings of biceps brachii muscles in patients with spastic cerebral palsy (CP). The maximal voluntary contraction (MVC) in the CP group was approximately one half of that of the normal group even after being normalized by the muscle ...

journal_title：Muscle & nerve

authors： Akataki K,Mita K,Itoh K,Suzuki N,Watakabe M

更新日期：1996-10-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to determine whether patients with carpal tunnel syndrome (CTS) manifest changes in early-stage motor function and to investigate the utility of a gyrosensor for quantitative evaluation of motor function. METHODS:Angular velocity signal was measured during finger tapping in...

journal_title：Muscle & nerve

authors： Seok HY,Kim JW,Kim YH,Park MH,Kwon DY

更新日期：2019-04-01 00:00:00

abstract：:Ocular movements and coordination require complex and integrated functions of somatic and autonomic nervous systems. Neurological disorders affecting these nervous systems may cause ocular dysfunction involving extraocular muscles and pupils. In this article, the prevalence, clinical presentations, and management of o...

journal_title：Muscle & nerve

authors： Evliyaoglu F,Karadag R,Burakgazi AZ

更新日期：2012-11-01 00:00:00

abstract：:The axonal distribution of voltage-dependent Na+ channels was determined during inflammatory demyelinating disease of the peripheral nervous system. Experimental allergic neuritis was induced in Lewis rats by active immunization. In diseased spinal roots Na+ channel immunofluorescence at many nodes of Ranvier changed ...

journal_title：Muscle & nerve

authors： Novakovic SD,Levinson SR,Schachner M,Shrager P

更新日期：1998-08-01 00:00:00

abstract：:This study aimed to clarify the morphologic variations of the Martin-Gruber anastomosis (MGA) by tracing the anastomotic fascicles. We used 102 upper limbs, and MGA was found in 39.2%. Among 12 instances of MGA between the branches innervating the flexor digitorum profundus muscle, eight anastomotic branches solely in...

journal_title：Muscle & nerve

authors： Lee KS,Oh CS,Chung IH,Sunwoo IN

更新日期：2005-01-01 00:00:00

abstract：:The voluntary discharge properties and axonal conduction velocity of single motor units were studied in patients with neuromuscular diseases with retained differentiation of the muscle fibers into type 1 and type 2, and in patients with late-onset hereditary distal myopathy in which muscle fibers have only intermediat...

journal_title：Muscle & nerve

authors： Borg J,Grimby L,Hannerz J

更新日期：1979-11-01 00:00:00

abstract：:Three well-characterized antimyosin heavy chain monoclonal antibodies (McAbs) were used as immunocytochemical reagents to study myosin isoform expression in relationship to adenosine triphosphatase (ATPase) defined fiber types in human muscle. The biopsy specimens were from patients with neurogenic muscle disease whos...

journal_title：Muscle & nerve

authors： Sawchak JA,Lewis S,Shafiq SA

更新日期：1989-08-01 00:00:00

abstract：:The development of the personal computer has simplified the process of quantitating sensory thresholds using various testing algorithms. We reviewed the technical aspects and reproducibility of different methods to determine threshold for light touch-pressure, vibration, thermal, and pain stimuli. Clinical uses and li...

journal_title：Muscle & nerve

authors： Chong PS,Cros DP

更新日期：2004-05-01 00:00:00

abstract：:Injuries to the lumbosacral plexus during labor and delivery have been reported in the literature for years, but have lacked electrophysiologic testing to substantiate the location of the nerve injury. We report 2 cases with comprehensive electrophysiologic testing which localizes the site of this obstetrical paralysi...

journal_title：Muscle & nerve

authors： Feasby TE,Burton SR,Hahn AF

更新日期：1992-08-01 00:00:00