Medullary infarcts may cause ipsilateral masseter reflex abnormalities.

Abstract:

:There is a suprasegmental influence on the masseter reflex (MassR) in animals, which is mediated via the fifth nerve spinal nucleus (5SpN). Corresponding data in humans are lacking. Out of 268 prospectively recruited patients with clinical signs of acute brainstem infarctions, we identified 38 with magnetic resonance imaging (MRI)-documented unilateral infarcts caudal to the levels of the fifth nerve motor and main sensory nuclei. All had biplanar T2- and echo planar diffusion-weighted MRI and MassR testing. Five patients (13%) had ipsilateral MassR abnormalities. In all, the infarcts involved the region of the 5SpN. Patients with medullary infarcts involving the region of the 5SpN may thus have ipsilateral MassR abnormalities. This possibly represents an interruption of an excitatory projection mediated via the 5SpN to masseter motoneurons in the fifth nerve motor nucleus. MassR abnormalities with medullary lesions restrict the topodiagnostic value of the MassR.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Thömke F,Marx JJ,Cruccu G,Stoeter P,Hopf HC

doi

10.1002/mus.20829

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

477-81

issue

4

eissn

0148-639X

issn

1097-4598

journal_volume

36

pub_type

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