Short-term aerobic training response in chronic myopathies.

abstract：:This longitudinal study of 194 patients with sporadic ALS demonstrated that it is possible for physicians to predict the approximate survival time for an individual ALS patient given: (1) the age of the patient, (2) the duration of his weakness and (3) an estimate of his clinical disability (ALS Score). This informati...

journal_title：Muscle & nerve

authors： Jablecki CK,Berry C,Leach J

更新日期：1989-10-01 00:00:00

abstract：:Electrodiagnostic studies were analyzed in patients with neuropathy associated with IgM monoclonal proteins, 7 with anti-myelin associated glycoprotein reactivity (MAG) and 7 nonreactive to MAG. The findings were distinctly different in the two groups. The electrodiagnostic studies of all the MAG-reactive patients had...

journal_title：Muscle & nerve

authors： Kelly JJ Jr

更新日期：1990-12-01 00:00:00

abstract：:The mdx mouse, an animal model used to study Duchenne muscular dystrophy, has a nonsense mutation in exon 23 of the dystrophin gene which should result in a truncated protein that cannot be correctly localized at the sarcolemma of the muscle fibers. Immunohistochemical staining with antidystrophin antibodies has shown...

journal_title：Muscle & nerve

authors： Wilton SD,Dye DE,Laing NG

更新日期：1997-06-01 00:00:00

abstract：:Muscle makes up the largest tissue volume of the body, yet its size makes muscle-specific therapy difficult. This becomes particularly relevant when approaches to gene therapy for inherited myopathies are evaluated. Thus, a mechanism to target constructs or pharmaceuticals to muscle following intravenous injection wou...

journal_title：Muscle & nerve

authors： Samoylova TI,Smith BF

更新日期：1999-04-01 00:00:00

abstract：:Guillain-Barré syndrome (GBS) is an inflammatory polyradiculoneuropathy associated with numerous viral infections. Recently, there have been many case reports describing the association between coronavirus disease-2019 (COVID-19) and GBS, but much remains unknown about the strength of the association and the features ...

journal_title：Muscle & nerve

authors： Caress JB,Castoro RJ,Simmons Z,Scelsa SN,Lewis RA,Ahlawat A,Narayanaswami P

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to assess age- and gender-specific incidence rates (IRs) of acetylcholine receptor (AChR)-antibody-positive myasthenia gravis (MG) in South Africa, and geographical variations in incidence. METHODS:IRs were calculated from positive AChR-antibody laboratory data between 2011 and 2...

journal_title：Muscle & nerve

authors： Mombaur B,Lesosky MR,Liebenberg L,Vreede H,Heckmann JM

更新日期：2015-04-01 00:00:00

abstract：:Masseter (MR) and blink reflexes (BL) were investigated in 51 patients with internuclear ophthalmoplegia (INO) due to multiple sclerosis (28) and lacunar infarction (23). The MR was abnormal in 20 of 23 cases with bilateral INO and in 21 of 28 with unilateral INO. The R1 component of the BL (BL-R1) was abnormal in 7 o...

journal_title：Muscle & nerve

authors： Hopf HC,Thömke F,Gutmann L

更新日期：1991-04-01 00:00:00

abstract：:We studied membrane ultrastructural localization of anionic phospholipids (AP) and sialic acid (SA) calcium binding sites in muscle biopsies from Duchenne muscular dystrophy (DMD) and 3 Becker's muscular dystrophy (BMD) patients using polymyxin B (PXB) and limulus polyphemus (LP) as cytochemical markers. We found that...

journal_title：Muscle & nerve

authors： Moggio M,Fagiolari G,Prelle A,Gallanti A,Sciacco M,Scarlato G

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Our pilot study tested the feasibility and performance of an eye-controlled power wheelchair for amyotrophic lateral sclerosis (ALS) patients. METHODS:In this prospective pilot study, participants drove the wheelchair three times around an indoor course. We assessed the time to complete the course; starting...

journal_title：Muscle & nerve

authors： Elliott MA,Malvar H,Maassel LL,Campbell J,Kulkarni H,Spiridonova I,Sophy N,Beavers J,Paradiso A,Needham C,Rifley J,Duffield M,Crawford J,Wood B,Cox EJ,Scanlan JM

更新日期：2019-11-01 00:00:00

abstract：:L1 radiculopathy is very rare and difficult to diagnose with needle electromyography. A patient presented with pain and hypesthesia on the anterolateral aspect of the left thigh. Nerve conduction studies and needle electromyography were normal, except for the quadratus lumborum and iliopsoas muscles, which showed abno...

journal_title：Muscle & nerve

authors： Yang SN,Kim DH

更新日期：2010-04-01 00:00:00

abstract：:Neuromyotonia or Isaacs' syndrome is a rare peripheral nerve hyperexcitability disorder caused by antibodies against potassium channels of myelinated axons. We present the high-density surface electromyographic (EMG) recordings of a patient with fasciculations and cramps due to neuromyotonia. To characterize the time ...

journal_title：Muscle & nerve

authors： Kleine BU,Stegeman DF,Drost G,Zwarts MJ

更新日期：2008-02-01 00:00:00

abstract：:We report on five patients who presented with unilateral or bilateral hypoplasia of the thenar eminence. X rays of the affected limbs showed varying degrees of malformation and underdevelopment of the thumb phalanges and first metacarpal bone, and of the carpal bones at the base of the thumb, indicating a developmenta...

journal_title：Muscle & nerve

authors： Cavanagh NP,Yates DA,Sutcliffe J

更新日期：1979-11-01 00:00:00

abstract：:This study aimed to clarify the morphologic variations of the Martin-Gruber anastomosis (MGA) by tracing the anastomotic fascicles. We used 102 upper limbs, and MGA was found in 39.2%. Among 12 instances of MGA between the branches innervating the flexor digitorum profundus muscle, eight anastomotic branches solely in...

journal_title：Muscle & nerve

authors： Lee KS,Oh CS,Chung IH,Sunwoo IN

更新日期：2005-01-01 00:00:00

abstract：:We propose a comprehensive model of spastic hypertonia based on clinical neurophysiology and validated using experimental data obtained from the pendulum test of the leg in 8 healthy volunteers and 15 spastic patients. This nonlinear computational model includes mechanical parameters and a stretch reflex representatio...

journal_title：Muscle & nerve

authors： Le Cavorzin P,Poudens SA,Chagneau F,Carrault G,Allain H,Rochcongar P

更新日期：2001-12-01 00:00:00

abstract：:Patients with chronic inflammatory demyelinating polyneuropathy (CIDP) received immune globulin intravenous, 10% caprylate/chromatography purified (IGIV-C, Gamunex; n=59) or placebo (n=58) every 3 weeks for up to 24 weeks (first period) in a randomized, double-blind, parallel-group, response-conditional, crossover stu...

journal_title：Muscle & nerve

authors： Bril V,Katzberg H,Donofrio P,Banach M,Dalakas MC,Deng C,Hanna K,Hartung HP,Hughes RA,Latov N,Merkies IS,van Doorn PA,ICE Study Group.

更新日期：2009-04-01 00:00:00

abstract：:Electrodiagnostic evaluation of patients with suspected polyneuropathy is useful for detecting and documenting peripheral abnormalities, identifying the predominant pathophysiology, and determining the prognosis for certain disorders. The electrodiagnostic classification of polyneuropathy is associated with morphologi...

journal_title：Muscle & nerve

authors： Donofrio PD,Albers JW

更新日期：1990-10-01 00:00:00

abstract：:Schwartz-Jampel syndrome (SJS) is an autosomal-recessive condition characterized by muscle stiffness and chondrodysplasia. It is due to loss-of-function hypomorphic mutations in the HSPG2 gene that encodes for perlecan, a proteoglycan secreted into the basement membrane. The origin of muscle stiffness in SJS is debate...

journal_title：Muscle & nerve

authors： Echaniz-Laguna A,Rene F,Marcel C,Bangratz M,Fontaine B,Loeffler JP,Nicole S

更新日期：2009-07-01 00:00:00

abstract：:The purpose of this study was to investigate the influence of an 8-week resistance training program on force steadiness and common drive for the vastus lateralis muscle. Eight untrained men performed a resistance training program. Before the program and at the end of each week, the subjects performed a trapezoid isome...

journal_title：Muscle & nerve

authors： Beck TW,Defreitas JM,Stock MS,Dillon MA

更新日期：2011-02-01 00:00:00

abstract：:The clinical effect of carbamazepine (CBZ) on neuromuscular transmission is described in two children who presented in coma with diffuse hypotonia and areflexia following CBZ overdose. Repetitive nerve stimulation (RNS) showed a decremental response only at high-frequency stimulation. With supportive care, the patient...

journal_title：Muscle & nerve

authors： Zaidat OO,Kaminski HJ,Berenson F,Katirji B

更新日期：1999-09-01 00:00:00

abstract：:Acquired neuromyotonia is characterized by hyperexcitability of motor nerves resulting in continuous muscle fiber activity. It occurs most often as a paraneoplastic syndrome in patients with cancers of the immune system. Antibodies against voltage-gated potassium channels (VGKCs) have been detected in some patients. P...

journal_title：Muscle & nerve

authors： Lahrmann H,Albrecht G,Drlicek M,Oberndorfer S,Urbanits S,Wanschitz J,Zifko UA,Grisold W

更新日期：2001-06-01 00:00:00

abstract：INTRODUCTION:Skin-derived precursor cells (SKPs) are neural crest progenitor cells that can attain a Schwann cell-like phenotype through in vitro techniques (SKP-SCs). We hypothesized that SKP-SCs could produce mature myelin and, in doing so, facilitate the recovery of a focal demyelination injury. METHODS:We unilater...

journal_title：Muscle & nerve

authors： Grochmal J,Dhaliwal S,Stys PK,van Minnen J,Midha R

更新日期：2014-08-01 00:00:00

abstract：:Motoneurons can be activated both reflexly and antidromically following electrical stimulation of peripheral nerves. These H reflexes and F waves are clinically useful responses which interface at the level of the peripheral nerves and the spinal cord. Because these responses are commonly employed in the electrodiagno...

journal_title：Muscle & nerve

authors： Fisher MA

更新日期：1992-11-01 00:00:00

abstract：INTRODUCTION:Intensive care unit (ICU) patients often develop weakness. Rehabilitation is initiated early to prevent physical deterioration, but knowledge of optimal training schedules is lacking. A reliable method to assess muscle activity during exercise is needed. In this study we explored the feasibility of electri...

journal_title：Muscle & nerve

authors： Sommers J,Van Den Boorn M,Engelbert RHH,Nollet F,Van Der Schaaf M,Horn J

更新日期：2018-11-01 00:00:00

abstract：:We studied histopathological changes in the biceps brachii muscle in relation to age and the degree of muscle weakness in 64 patients (aged 11-59 years) with myotonic dystrophy. The proportion of type 1 fibers was unaltered in the adolescent patients compared with control values, but increased with age. The average di...

journal_title：Muscle & nerve

authors： Tohgi H,Kawamorita A,Utsugisawa K,Yamagata M,Sano M

更新日期：1994-09-01 00:00:00

abstract：:Sera of patients with myasthenia gravis (MG) contain anti-acetylcholine receptor (AChR) IgG antibodies (Ab) which have different antigenic specificities. Three Ab types were detected: (1) MG-I, which forms immune complexes with AChR; (2) MG-C, which decreases binding of AChR to concanavalin A; and MG-B, which blocks a...

journal_title：Muscle & nerve

authors： Mittag T,Massa T,Kornfeld P,Papatestas A,Bender A,Genkins G

更新日期：1981-01-01 00:00:00

abstract：:Motor evoked potentials (MEPs) obtained by electrical root stimulation and F waves were used to examine the proximal nerve conduction velocity (CV) to tibialis anterior (TA), extensor digitorum brevis (EDB), flexor carpi radialis (FCR), and abductor pollicis brevis (APB) muscles in 40 humans. By subtracting motor late...

journal_title：Muscle & nerve

authors： Zwarts MJ,Guechev A

更新日期：1995-11-01 00:00:00

abstract：:Earlier studies have shown that prior denervation of muscle prevents myotonia induced by 2,4-dichlorophenoxy acetic acid (2,4-D) both in vivo and in vitro. This work studied the effect of reinnervation on 2,4-D myotonia. Twenty Sprague-Dawley rats were injected with 2,4-D at specific intervals following unilateral sci...

journal_title：Muscle & nerve

authors： Al-Sulaiman A,Al-Rajeh S,Iyer V

更新日期：1986-05-01 00:00:00

abstract：:Immunocytochemical analysis of muscle specimens from 5 patients with acute quadriplegic myopathy indictes that depletion of either fast or slow myosin occurs in this disorder. The initial lesion consists of focal myosin loss in nonatrophic fibers. Other structural proteins (actin, titin, nebulin) are spared or affecte...

journal_title：Muscle & nerve

authors： Showalter CJ,Engel AG

更新日期：1997-03-01 00:00:00

abstract：:Body components were measured noninvasively in patients with neuromuscular disease by using dual-energy X-ray absorptiometry (DXA), capable of separately analyzing fat, bone, and muscle content. In all patients with muscle atrophy of myogenic or neurogenic origin, muscle mass was markedly reduced. Although all three c...

journal_title：Muscle & nerve

authors： Kanda F,Fujii Y,Takahashi K,Fujita T

更新日期：1994-04-01 00:00:00

abstract：INTRODUCTION:Nebulin is a giant actin-binding protein in the thin filament of the skeletal muscle sarcomere. Studies of nebulin interactions are limited by the size, complexity, and poor solubility of the protein. We divided the nebulin super-repeat region into a super-repeat panel, and studied nebulin/actin interactio...

journal_title：Muscle & nerve

authors： Laitila J,Lehtonen J,Lehtokari VL,Sagath L,Wallgren-Pettersson C,Grönholm M,Pelin K

更新日期：2019-01-01 00:00:00