Abstract:
:Motoneurons can be activated both reflexly and antidromically following electrical stimulation of peripheral nerves. These H reflexes and F waves are clinically useful responses which interface at the level of the peripheral nerves and the spinal cord. Because these responses are commonly employed in the electrodiagnostic evaluation of patients, an understanding of their physiology and clinical applications is important. These are reviewed. Reasoning from the physiology, both the value and limitations of H-reflex and F-wave studies are considered for disorders of peripheral nerves, roots, and the central nervous system. Theoretical concepts about the physiology and pathophysiology of the nervous system based on H-reflex and F-wave data are also discussed.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Fisher MAdoi
10.1002/mus.880151102subject
Has Abstractpub_date
1992-11-01 00:00:00pages
1223-33issue
11eissn
0148-639Xissn
1097-4598journal_volume
15pub_type
杂志文章,评审相关文献
MUSCLE & NERVE文献大全abstract::With the exception of thymectomy, immune modulatory treatment strategies and clinical trials in myasthenia gravis over the past 50 y were mainly borrowed from experience in other nonneurologic autoimmune disorders. The current experimental therapy paradigm has significantly changed such that treatments directed agains...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.26919
更新日期:2020-11-01 00:00:00
abstract::Recurrent idiopathic lumbosacral plexopathy has rarely been reported in the literature. The present report describes a 59-year-old man presenting with recurrent episodes of acute leg pain, followed by weakness. After each episode, symptoms progressed for several months before peaking. Thereafter, gradual recovery ensu...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/1097-4598(200009)23:9<1439::aid-mus18>3.0.
更新日期:2000-09-01 00:00:00
abstract::Factors that affect the shape of the so-called "normal cloud" of the turns and amplitude measurements of the electromyographic interference pattern are investigated. As the force of voluntary contraction increases from low to moderate levels, the number of turns in the signal increase faster than does the mean amplitu...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880140103
更新日期:1991-01-01 00:00:00
abstract::A previously reported patient presenting sensory-dominant neuropathy with antiganglioside antibodies, bound preferentially to polysialogangliosides including GD1b, was autopsied. While axonal degeneration was predominant in the sural nerve, many demyelinated fibers were present in the spinal roots. Dorsal roots had un...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199910)22:10<1426::aid-mus
更新日期:1999-10-01 00:00:00
abstract::The pattern of an abnormal median-normal sural (AMNS) sensory response is associated with acute and chronic inflammatory demyelinating polyradiculoneuropathy (AIDP and CIDP) and considered unusual in other types of neuropathy, although specificity and sensitivity of this pattern have not been evaluated. We compared se...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880160304
更新日期:1993-03-01 00:00:00
abstract:INTRODUCTION:We evaluated the contribution of denervation-related molecular processes to rotator cuff muscle degeneration after tendon release. METHODS:We assessed the levels of myogenic (myogenin and myogenic differentiation factor [myoD]) and proadipogenic (peroxisome proliferator-activated receptor γ) transcription...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26316
更新日期:2019-01-01 00:00:00
abstract::Single muscle fibers were prepared from biopsy specimens of Duchenne muscular dystrophy (DMD), normal, and neuromuscular disease controls. Single muscle cells were classified as type 1, type 2, or intermediate by the skinned fiber method. The intermediate fiber was most abundant in DMD, comprising 29% of fibers examin...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880050511
更新日期:1982-05-01 00:00:00
abstract:INTRODUCTION:Onabotulinum toxin serotype A (BT-A) is used for a variety of motor and sensory disorders related to abnormal muscle activity. METHODS:We developed a high-resolution rodent model to allow precise determination of the effect of BT-A dose (measured in units) and injectate volume (measured in μl) on the effi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23983
更新日期:2014-05-01 00:00:00
abstract::Danon disease is a rare X-linked dominant disorder caused by lysosomal-associated membrane protein 2 (LAMP2) deficiency and is characterized by hypertrophic cardiomyopathy, cardiac conduction abnormalities, skeletal vacuolar myopathy, variable degree of mental retardation, and peripheral pigmentary retinopathy. We des...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20930
更新日期:2008-03-01 00:00:00
abstract::Serum creatine kinase (CK) activity, calcium (Ca) and magnesium (Mg) contents of skeletal muscle and isolated mitochondria, as well as oxidative phosphorylation of X-linked muscular dystrophic (mdx) mice were compared with normal control animals at ages 5, 10, and 23 weeks. Serum CK is elevated in mdx mice at all ages...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880110809
更新日期:1988-08-01 00:00:00
abstract::Data are scarce relating to the plasticity with strength training of dynamic muscle performance in older humans. Hence, we investigated alterations in the torque-velocity relation with strength training in old age, and their origin. Knee extension and leg-press exercises were performed three times per week for 14 week...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20275
更新日期:2005-03-01 00:00:00
abstract::Platelet-derived microparticle (PDMP) levels were measured using an enzyme-linked immunosorbent assay (ELISA) to elucidate the role of platelet activation in patients with polymyositis or dermatomyositis (PM/DM). PDMP levels in active PM/DM patients (median 13.3 U/ml, interquartile range 9.9-20.7 U/ml, n = 16) and tho...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21311
更新日期:2009-05-01 00:00:00
abstract::Clinical testing for neuromuscular dysfunction is supported by an extensive amount of excellent basic information about normal and abnormal subcellular physiology and ultrastructure. This information provides an essential frame of reference for describing the rationale of single-fiber electromyography (SFEMG). SFEMG i...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.880120802
更新日期:1989-08-01 00:00:00
abstract:INTRODUCTION:Hereditary transthyretin (hATTR) amyloidosis is a progressive, degenerative disease, with peripheral neuropathy, cardiomyopathy, and other clinical manifestations. In this study we examine the impact of hATTR amyloidosis on quality of life (QOL). METHODS:Neuropathy-specific QOL, measured with the Norfolk ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26515
更新日期:2019-08-01 00:00:00
abstract:INTRODUCTION:In this study we assessed the effect of paired stimuli on the latencies and amplitudes of the blink reflex. METHODS:Blink reflexes were performed with single and paired (5-ms interstimulus interval) stimuli in 47 patients. The changes in latencies between paired and single stimuli were calculated. RESULT...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.22034
更新日期:2011-08-01 00:00:00
abstract::An infant presented with congenital weakness, hypotonia, arthrogryposis, atrial tachycardia, and a left intra-abdominal neuroblastoma. Muscle biopsy revealed marked excess of muscle spindles with atrophy of extrafusal fibers. The patient expired at age 14 months from progressive cardiorespiratory failure. Postmortem e...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/1097-4598(200101)24:1<138::aid-mus22>3.0.c
更新日期:2001-01-01 00:00:00
abstract:INTRODUCTION:Low-intensity electrical stimuli of digital nerves may generate a double peak potential (DPp), composed of a cathodal (caAP) and an anodal (anAP) potential in orthodromic recordings. METHODS:We studied the effects on caAP and anAP of stimuli of variable intensity, duration, and frequency. We also applied ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24957
更新日期:2016-06-01 00:00:00
abstract::A new approach to the quantification of fiber type grouping is presented, in which the distribution of histochemical type in a muscle cross section is regarded as a realization of a binary Markov random field (BMRF). Methods for the estimation of the parameters of this model are discussed. The first order BMRF, which ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880150617
更新日期:1992-06-01 00:00:00
abstract::Genetic testing is rapidly becoming an increasingly significant part of the diagnostic armamentarium of neuromuscular clinicians. Although technically easy to order, the results of such testing, whether positive or negative, have potentially enormous consequences for the individual tested and for family members. As a ...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.25400
更新日期:2016-12-01 00:00:00
abstract:INTRODUCTION:We studied neurodevelopmental and behavioral/emotional symptoms in patients with Duchenne muscular dystrophy (DMD). METHODS:Retrospective case series of neurodevelopmental and behavioral/emotional symptoms obtained through review of systems of 700 DMD patients in relation to dystrophin gene mutations. RE...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26803
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:In multifocal motor neuropathy (MMN), knowledge about the pattern of treatment response in a wide spectrum of muscle groups, distal as well as proximal, after intravenous immunoglobulin (IVIg) initiation is lacking. METHODS:Hand-held dynamometry data of 11 upper and lower limb muscles, from 47 patients wi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.27185
更新日期:2021-01-26 00:00:00
abstract::Ultrastructural, biochemical, and electrophysiological analyses were done on 12-14-month-old mice deficient for myelin-associated glycoprotein (MAG) to further characterize the neuropathy that develops as they age. Electron microscopy demonstrated normal myelin compaction and axonal degeneration in a large number of m...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.1159
更新日期:2001-10-01 00:00:00
abstract::The latency fluctuation of single motor unit potentials (MUPH) in the H-reflex is greater than the latency fluctuation of MUPs in the direct (MUPM) and recurrent (MUPF) responses. This has been attributed to the variability in the impulse generation at the site of nerve stimulation, and to the variation in the synapti...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880150604
更新日期:1992-06-01 00:00:00
abstract::A patient in perfect health prior to electrical shock developed an ALS-like syndrome after the shock. Onset of the disease occurred in the limb through which the shock entered, and subsequently followed a course well-described in previous case reports. Possible mechanisms of disease are discussed. ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880141008
更新日期:1991-10-01 00:00:00
abstract:INTRODUCTION:Similar to magnetic resonance imaging (MRI), electrical impedance myography (EIM) is dependent on the presence and location of water in muscle to assess neuromuscular diseases. We compared the 2 technologies in mdx mice to better understand their relationship. METHODS:EIM and MRI, using T2 relaxation and ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24573
更新日期:2015-10-01 00:00:00
abstract::We prospectively studied the diagnostic utility of upper limb segmental reflexes in patients with suspected cervical radiculopathy (CR). Fifty-three patients (29 men and 24 women), referred for electrodiagnostic testing, were positive for at least one of four clinical criteria for CR: abnormal (1) history, (2) motor (...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199908)22:8<1075::aid-mus1
更新日期:1999-08-01 00:00:00
abstract::The coronavirus disease 2019 (COVID-19) pandemic has resulted in the reorganization of health-care settings affecting clinical care delivery to patients with Duchenne and Becker muscular dystrophy (DBMD) as well as other inherited muscular dystrophies. The magnitude of the impact of this public health emergency on the...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.26902
更新日期:2020-07-01 00:00:00
abstract::Loss of cells from the motor system occurs during the normal aging process, leading to reduction in the complement of motor neurons and muscle fibers. The latter age-related decrease in muscle mass has been termed "sarcopenia" and is often combined with the detrimental effects of a sedentary lifestyle in older adults,...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.1215
更新日期:2002-01-01 00:00:00
abstract::The reliability of motor unit number estimation (MUNE) for assessment of the long-term course of ALS is dependent on the reproducibility of the technique. We report our results with the statistical method of MUNE on the ulnar nerve/hypothenar muscle in 16 ALS patients who were studied on 52 occasions. On each occasion...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-4598(200002)23:2<193::aid-mus8>
更新日期:2000-02-01 00:00:00
abstract::Familial amyotrophic lateral sclerosis (ALS) with the autosomal-recessively inherited D90A CuZn-superoxide dismutase (CuZn-SOD) mutation is characterized by a stereotypic slowly progressive, distinctive phenotype and very slow central motor conduction. To determine the basis of this slowing, we assessed corticomotoneu...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/1097-4598(200101)24:1<89::aid-mus10>3.0.co
更新日期:2001-01-01 00:00:00