Systematic test of neurotoxin dose and volume on muscle function in a rat model.

abstract：:L-carnitine stimulated CO2 production from 1-14C pyruvate in mitochondria from human skeletal muscle nearly twofold. A comparable increase in the pyruvate dehydrogenase complex (PDHC) activity was seen. Moreover, in the presence of L-carnitine and at pyruvate concentration greater than 0.25 mM, this effect was associa...

journal_title：Muscle & nerve

authors： Uziel G,Garavaglia B,Di Donato S

更新日期：1988-07-01 00:00:00

abstract：:The distribution of collagen types I, III, and V and fibronectin was investigated by means of immunofluorescent techniques in denervated and normal rat skeletal muscle. During a period of 28 days, a distinct atrophy developed in the denervated gastrocnemius muscle and was accompanied by an increase in types I and III ...

journal_title：Muscle & nerve

authors： Salonen V,Lehto M,Kalimo M,Penttinen R,Aro H

更新日期：1985-02-01 00:00:00

abstract：INTRODUCTION:Skin-derived precursor cells (SKPs) are neural crest progenitor cells that can attain a Schwann cell-like phenotype through in vitro techniques (SKP-SCs). We hypothesized that SKP-SCs could produce mature myelin and, in doing so, facilitate the recovery of a focal demyelination injury. METHODS:We unilater...

journal_title：Muscle & nerve

authors： Grochmal J,Dhaliwal S,Stys PK,van Minnen J,Midha R

更新日期：2014-08-01 00:00:00

abstract：:Patients with an idiopathic increase in serum creatine kinase (CK) levels (hyper-CK-emia) have a benign prognosis, but symptoms may be disabling in daily life. Previous studies have suggested that physical exercise increases the severity of complaints in these patients. We studied whether maximal and submaximal bouts ...

journal_title：Muscle & nerve

authors： Reijneveld JC,Te Boekhorst BC,Zonderland ML,Kalmijn S,Notermans NC

更新日期：2002-12-01 00:00:00

abstract：:Repetitive nerve stimulation (RNS) of the median nerve is rarely studied in myasthenia gravis (MG). We performed a retrospective analysis of RNS studies performed on 448 patients at our center between 2010 and 2016. Among 95 patients with MG, an abnormal decrement of the compound muscle action potential amplitude was ...

journal_title：Muscle & nerve

authors： Lee TH,Li Y

更新日期：2019-12-01 00:00:00

abstract：:There are several pathogenic mechanisms of peripheral nerve involvement in patients with monoclonal dysglobulinemia. Intranervous proliferation of malignant cells, immunoglobulin, or amyloid deposits in the endoneurial space can only be determined by examination of nerve biopsy specimens. We present clinical, electrop...

journal_title：Muscle & nerve

authors： Vallat JM,Magy L,Richard L,Piaser M,Sindou P,Calvo J,Ghorab K,Cros D

更新日期：2008-07-01 00:00:00

abstract：INTRODUCTION:The aim of this work was to determine the effect of chronic alcohol exposure on peripheral nerves in a nutritionally balanced rat model of alcoholism. METHODS:Three different strains of adult male rats were pair-fed for 8 weeks with isocaloric liquid diets containing 0% or 37% ethanol. Nerve conduction st...

journal_title：Muscle & nerve

authors： Mellion ML,Nguyen V,Tong M,Gilchrist J,De La Monte S

更新日期：2013-08-01 00:00:00

abstract：:Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and membranous glomerulonephritis (MGN) are both autoimmune disorders that are rarely observed concurrently. We describe a patient who developed MGN nearly 20 years after the onset of CIDP, resulting in a secondary progression of his neuropathy. He respo...

journal_title：Muscle & nerve

authors： Smyth S,Menkes DL

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:This study was designed to assess the effect of extracorporeal shock-wave lithotripsy (ESWL) exposure of the parotid gland on oxidative stress and some trace element levels in the facial nerves of rats. METHODS:Twelve male Wistar albino rats were divided into two groups, each consisting of 6 animals. The ...

journal_title：Muscle & nerve

authors： Kavak S,Garca MF,Gecit I,Meral I,Cengiz N,Demir H

更新日期：2012-04-01 00:00:00

abstract：:Compound muscle action potentials (CMAPs) evoked by magnetic brain stimuli are larger if the subject provides a steady background voluntary contraction of the target muscle. This facilitation could be due either to cortical or spinal mechanisms, or both. Both magnetic and electrical stimuli given immediately after the...

journal_title：Muscle & nerve

authors： Mills KR,Kimiskidis V

更新日期：1996-08-01 00:00:00

abstract：:Contractions of rat extensor digitorum longus (EDL, a fast muscle) and soleus (SOL, a slow muscle) muscles of different ages (1-4 weeks) were recorded in vitro with direct stimulation and at different temperatures (range 35-10 degrees C). Twitch tension in 4-week-old EDL muscle increased in cooling from 35 to 20 degre...

journal_title：Muscle & nerve

authors： Wylie SR,Ranatunga KW

更新日期：1987-11-01 00:00:00

abstract：:Electrophysiologic detection of the first signs of gastrocnemius muscle reinnervation shows that after a single localized freezing of the rat sciatic nerve, isaxonine does not significantly increase the rate of axonal regeneration. However, this drug does significantly enhance axonal sprouting, as it induces an increa...

journal_title：Muscle & nerve

authors： Pecot-Dechavassine M,Mira JC

更新日期：1985-02-01 00:00:00

abstract：:The clinical efficacy of functional electrical stimulation (FES) is limited by the rapid onset of fatigue. Functional electrical stimulation applications typically stimulate skeletal muscles with constant-frequency trains (CFTs). Our laboratory has identified trains that we call doublet-frequency trains (DFTs) and tha...

journal_title：Muscle & nerve

authors： Scott WB,Lee SC,Johnston TE,Binder-Macleod SA

更新日期：2005-05-01 00:00:00

abstract：INTRODUCTION:Stroke-related changes in maximal dynamic hip flexor muscle fatigability may be more relevant functionally than isometric hip flexor fatigability. METHODS:Ten chronic stroke survivors performed 5 sets of 30 hip flexion maximal dynamic voluntary contractions (MDVC). A maximal isometric voluntary contractio...

journal_title：Muscle & nerve

authors： Kuhnen HR,Rybar MM,Onushko T,Doyel RE,Hunter SK,Schmit BD,Hyngstrom AS

更新日期：2015-03-01 00:00:00

abstract：INTRODUCTION:Because paradoxical sleep deprivation (PSD) induces a catabolic hormone profile, we sought to evaluate the morphology of the tibialis anterior (TA) muscle and testosterone and corticosterone levels of paradoxical sleep-deprived rats. METHODS:Three study groups of rats were established: the first group was...

journal_title：Muscle & nerve

authors： Dattilo M,Antunes HK,Medeiros A,Mônico-Neto M,Souza Hde S,Lee KS,Tufik S,de Mello MT

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:In this study we investigated the influence of gender and obesity on electrical current thresholds in an attempt to optimize the application of skeletal muscle electrical stimulation (ES) in clinical practice. METHODS:Thirty-two obese and 35 age-matched, non-obese men and women received graded ES to the q...

journal_title：Muscle & nerve

authors： Maffiuletti NA,Morelli A,Martin A,Duclay J,Billot M,Jubeau M,Agosti F,Sartorio A

更新日期：2011-08-01 00:00:00

abstract：:Masseter (MR) and blink reflexes (BL) were investigated in 51 patients with internuclear ophthalmoplegia (INO) due to multiple sclerosis (28) and lacunar infarction (23). The MR was abnormal in 20 of 23 cases with bilateral INO and in 21 of 28 with unilateral INO. The R1 component of the BL (BL-R1) was abnormal in 7 o...

journal_title：Muscle & nerve

authors： Hopf HC,Thömke F,Gutmann L

更新日期：1991-04-01 00:00:00

abstract：:Normal motor units (MUs) were simulated and their architecture altered to simulate the changes produced by myopathy. The concentric needle electromyographic recordings of motor unit action potentials (MUAPs) from the MUs were then also simulated. These simulated MUAPs showed features that are seen in myopathy: normal ...

journal_title：Muscle & nerve

authors： Nandedkar SD,Sanders DB

更新日期：1989-03-01 00:00:00

abstract：:Single-fiber electromyography (SFEMG) demonstrates abnormal jitter in virtually all (99%) patients with myasthenia gravis (MG). One muscle, the extensor digitorum communis, is abnormal in most patients with this disease, but to obtain the maximum diagnostic sensitivity, it may be necessary to examine other muscles, es...

journal_title：Muscle & nerve

authors： Sanders DB,Howard JF Jr

更新日期：1986-11-01 00:00:00

abstract：:To determine the contributions of neural and mechanical mechanisms to the limits in the range of motion (ROM) about a joint, we studied the effects of 30 sessions of static stretch training on the characteristics of the plantar-flexor muscles in 12 subjects. Changes in the maximal ankle dorsiflexion and the torque pro...

journal_title：Muscle & nerve

authors： Guissard N,Duchateau J

更新日期：2004-02-01 00:00:00

abstract：INTRODUCTION:Tarsal tunnel syndrome (TTS) arises from tibial nerve damage under the flexor retinaculum of the fibro-osseus tunnel at the medial malleolus. It is notoriously difficult to diagnose, as many other foot pathologies result in a similar clinical picture. We examined the additional value of nerve ultrasound in...

journal_title：Muscle & nerve

authors： Samarawickrama D,Therimadasamy AK,Chan YC,Vijayan J,Wilder-Smith EP

更新日期：2016-06-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIg) is a useful tool in the treatment of a variety of neuromuscular disorders. Though IVIg therapy is generally safe, hemolytic anemia is a potentially serious complication that is often overlooked, and is currently not listed in product inserts. We analyzed 45 patients who received IVIg ...

journal_title：Muscle & nerve

authors： Wilson JR,Bhoopalam H,Fisher M

更新日期：1997-09-01 00:00:00

abstract：INTRODUCTION:We examined the effects of pain site and intensity on function in patients with myotonic dystrophy type 1 (DM1) and facioscapulohumeral muscular dystrophy (FSHD) and chronic pain. METHODS:Questionnaires assessing pain sites, pain extent (number of sites), pain intensity, and pain interference were complet...

journal_title：Muscle & nerve

authors： Miró J,Gertz KJ,Carter GT,Jensen MP

更新日期：2014-06-01 00:00:00

abstract：INTRODUCTION:Psoriasis is a T-cell-mediated skin disorder with uncommon extracutaneous manifestations. Rare patients with psoriasis and myopathy have been reported. METHODS:We conducted a retrospective review of medical records of psoriasis patients seen at the Mayo Clinic during the period from January 1, 1996 to May...

journal_title：Muscle & nerve

authors： Liewluck T,Ernste FC,Tracy JA

更新日期：2013-11-01 00:00:00

abstract：:As caveolin-3 deficiencies may explain persistent hyper-CK-emia, we performed CAV3 gene mutation analysis and immunohistochemistry for caveolin-3 in 31 patients with idiopathic hyper-CK-emia. In 2 of 29 patients who donated blood, variants in the CAV3 gene were detected. Although immunohistochemical analysis strongly ...

journal_title：Muscle & nerve

authors： Reijneveld JC,Ginjaar IB,Frankhuizen WS,Notermans NC

更新日期：2006-11-01 00:00:00

abstract：INTRODUCTION:We adopted a proteomics-based approach to gain insights into phenotypic differences between A/J and B10.SJL murine dysferlinopathy models. METHODS:We optimized immunoblotting of dysferlin by preparing homogenates of the tibialis anterior (TA) muscle under several different conditions. We compared TA muscl...

journal_title：Muscle & nerve

authors： Mueller AL,Desmond PF,Hsia RC,Roche JA

更新日期：2014-08-01 00:00:00

abstract：:Morvan's syndrome is a rare disorder characterized by neuromyotonia, hyperhidrosis, and central nervous system dysfunction. We report a patient with features of this syndrome, but who initially presented with breathing difficulties. Concentric needle electromyography showed an abundance of myokymic and neuromyotonic d...

journal_title：Muscle & nerve

authors： Löscher WN,Wanschitz J,Reiners K,Quasthoff S

更新日期：2004-08-01 00:00:00

abstract：:The voluntary discharge properties and axonal conduction velocity of single motor units were studied in patients with neuromuscular diseases with retained differentiation of the muscle fibers into type 1 and type 2, and in patients with late-onset hereditary distal myopathy in which muscle fibers have only intermediat...

journal_title：Muscle & nerve

authors： Borg J,Grimby L,Hannerz J

更新日期：1979-11-01 00:00:00

abstract：INTRODUCTION:Previous studies of limb-girdle muscular dystrophy type 2A (LGMD2A) patients in many countries have suggested a heterogeneous genetic and clinical spectrum, but the genotypes and phenotypes of Chinese LGMD2A patients remain unclear. METHODS:We directly screened calpain-3 (CAPN3) in 18 Chinese Han subjects...

journal_title：Muscle & nerve

authors： Luo SS,Xi JY,Zhu WH,Zhao CB,Lu JH,Lin J,Wang Y,Lu J,Qiao K

更新日期：2012-11-01 00:00:00

abstract：:We investigated 16 patients with Fabry's disease (eight hemizygous men and eight heterozygous women) in one family. We used constant current perception threshold (CPT) testing, which evaluated three major sensory nerve fiber populations, to assess subjective complaints of pain and paresthesias. We also examined clinic...

journal_title：Muscle & nerve

authors： Ro LS,Chen ST,Tang LM,Hsu WC,Chang HS,Huang CC

更新日期：1999-11-01 00:00:00