Coincident membranous glomerulonephritis and chronic inflammatory demyelinating polyradiculoneuropathy: questioning the autoimmunity hypothesis.

Abstract:

:Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and membranous glomerulonephritis (MGN) are both autoimmune disorders that are rarely observed concurrently. We describe a patient who developed MGN nearly 20 years after the onset of CIDP, resulting in a secondary progression of his neuropathy. He responded dramatically to a novel regimen of plasma exchange and methotrexate. We propose a mechanism other than autoimmunity for the coincidence of these disorders and discuss the theoretical superiority of the treatment regimen that he received.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Smyth S,Menkes DL

doi

10.1002/mus.20841

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

130-5

issue

1

eissn

0148-639X

issn

1097-4598

journal_volume

37

pub_type

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