Abstract:
INTRODUCTION:In this study we aimed to clarify whether muscle ultrasound (US) of the forearm can be used to differentiate between patients with sporadic inclusion body myositis (s-IBM) and those with s-IBM-mimicking diseases. METHODS:We compared the echo intensity (EI) of the flexor digitorum profundus (FDP) muscle and the flexor carpi ulnaris (FCU) muscles in patients with s-IBM (n = 6), polymyositis/dermatomyositis (PM/DM; n = 6), and amyotrophic lateral sclerosis (ALS; n = 6). RESULTS:We identified EI abnormalities in 100% of patients with s-IBM, 33% of those with PM/DM, and 33% of those with ALS. An "FDP-FCU echogenicity contrast," a US pattern involving a higher EI in the FDP than in the FCU, was observed in all patients with s-IBM, but in none of those with PM/DM or ALS. CONCLUSIONS:FDP-FCU echogenicity contrast in muscle US is a sensitive diagnostic indicator of s-IBM.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Noto Y,Shiga K,Tsuji Y,Kondo M,Tokuda T,Mizuno T,Nakagawa Mdoi
10.1002/mus.24056subject
Has Abstractpub_date
2014-05-01 00:00:00pages
745-8issue
5eissn
0148-639Xissn
1097-4598journal_volume
49pub_type
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