Abstract:
:Little attention has been paid to small-fiber dysfunction in carpal tunnel syndrome (CTS) although its symptoms are common. This study investigates vasomotor dysfunction, which is controlled by small nerve fibers, in patients with CTS compared with control subjects. Vasomotor function was quantified by measuring, with laser Doppler velocimetry, skin vasoconstriction induced by a eutectic mixture of local anesthetic (EMLA) cream over digit tips 3, 4, and 5. Hands with CTS (n = 32) compared with controls (n = 19) demonstrated significantly reduced vasoconstriction in digits 3 and 4, but not digit 5. A blood flow ratio (digit 3/5) of less than 0.73 identified CTS in 69% with 68% specificity. Testing for vasomotor dysfunction in CTS allows for more comprehensive neurophysiological testing, which is heavily biased towards large nerve fibers.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Wilder-Smith EP,Fook-Chong S,Chew SE,Chow A,Guo Ydoi
10.1002/mus.10475subject
Has Abstractpub_date
2003-11-01 00:00:00pages
582-6issue
5eissn
0148-639Xissn
1097-4598journal_volume
28pub_type
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