AAEE Minimonograph #33: electrodiagnostic approach to defects of neuromuscular transmission.

Abstract:

:Clinical testing for neuromuscular dysfunction is supported by an extensive amount of excellent basic information about normal and abnormal subcellular physiology and ultrastructure. This information provides an essential frame of reference for describing the rationale of single-fiber electromyography (SFEMG). SFEMG in turn helps to explain the more conventional clinical testing of neuromuscular function by repetitive nerve stimulation (RNS). Electrical findings in myasthenia gravis, Lambert-Eaton myasthenic syndrome, and botulinum intoxication are discussed from the subcellular level via the cellular level (SFEMG) to the integrated responses of whole muscle (RNS) as a rational means of understanding the technique of clinical repetitive nerve stimulation.

journal_name

Muscle Nerve

journal_title

Muscle & nerve

authors

Keesey JC

doi

10.1002/mus.880120802

subject

Has Abstract

pub_date

1989-08-01 00:00:00

pages

613-26

issue

8

eissn

0148-639X

issn

1097-4598

journal_volume

12

pub_type

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