Electrophysiological studies in a mouse model of Schwartz-Jampel syndrome demonstrate muscle fiber hyperactivity of peripheral nerve origin.

abstract：:Superimposed electrical stimulation techniques can be used to detect central activation failure (CAF), that is, incomplete central nervous system recruitment or suboptimal activation of motor units. The purpose of this study was to evaluate the effects of two stimulation parameters on perceived discomfort and torque i...

journal_title：Muscle & nerve

authors： Miller M,Downham D,Lexell J

更新日期：2003-01-01 00:00:00

abstract：:To elucidate whether the frontal components of scalp somatosensory evoked potentials (SEPs) depend on the type of peripheral input, we compared scalp SEPs in response to electrical stimuli applied to: (i) the proximal phalanx of the thumb, involving both deep and cutaneous afferents; and (ii) the distal phalanx of the...

journal_title：Muscle & nerve

authors： Restuccia D,Valeriani M,Barba C,Le Pera D,Tonali P,Mauguière F

更新日期：1999-07-01 00:00:00

abstract：:Because of their central role in muscle development and maintenance, MEF2 family members represent excellent candidate effectors of the muscle pathology in myotonic dystrophy (DM). We investigated the expression and alternative splicing of all four MEF2 genes in muscle from neuromuscular disorder (NMD) patients, inclu...

journal_title：Muscle & nerve

authors： Bachinski LL,Sirito M,Böhme M,Baggerly KA,Udd B,Krahe R

更新日期：2010-12-01 00:00:00

abstract：:Denervation induces muscle fiber atrophy and changes in the gene expression rates of skeletal muscle. Electrical stimulation (ES) is a procedure generally used to treat denervated muscles in humans. This study evaluated the effect of ES based on chronaxie and rheobase on the expression of the myoD and atrogin-1 genes ...

journal_title：Muscle & nerve

authors： Russo TL,Peviani SM,Freria CM,Gigo-Benato D,Geuna S,Salvini TF

更新日期：2007-01-01 00:00:00

abstract：:Two sisters presented with distal weakness and their muscle biopsy was dystrophic. This distal muscular dystrophy has an autosomal recessive inheritance and its features are somewhat different from the more common autosomal dominant distal muscular dystrophy and include: a) onset in early adult life; b) involvement of...

journal_title：Muscle & nerve

authors： Scoppetta C,Vaccario ML,Casali C,Di Trapani G,Mennuni G

更新日期：1984-07-01 00:00:00

abstract：:Since peripheral nerve has a large ischemic safety factor, hypothermia, by reducing metabolic demands, is potentially an efficacious technique to rescue nerve from ischemic fiber degeneration (IFD). We therefore evaluated the influence of temperature on the severity of IFD resulting from a standard ischemic stress. Is...

journal_title：Muscle & nerve

authors： Kihara M,Schmelzer JD,Kihara Y,Smithson IL,Low PA

更新日期：1996-02-01 00:00:00

abstract：:Somatosensory evoked potentials (SEPs) and motor evoked potentials (MEPs) to transcranial and spinal stimulation from upper and lower limb muscles were elicited in 13 patients with syringomyelia. Seven had an associated Chiari type I anomaly. Diagnosis was confirmed by MRI. In 5 cases, SEPs and MEPs were performed bef...

journal_title：Muscle & nerve

authors： Nogués MA,Pardal AM,Merello M,Miguel MA

更新日期：1992-09-01 00:00:00

abstract：:Based on the known trophic effects of growth hormone (GH) on nerve and muscle 75 patients with ALS were treated for up to 18 months with synthetic human growth hormone (Protropin) or a placebo. The course of ALS was assessed serially using a quantitative (TQNE) neuromuscular and manual exam (MRC) and laboratory chemis...

journal_title：Muscle & nerve

authors： Smith RA,Melmed S,Sherman B,Frane J,Munsat TL,Festoff BW

更新日期：1993-06-01 00:00:00

abstract：INTRODUCTION:In this study we aimed to identify prognostic factors of ulnar neuropathy at the elbow (UNE) and developed a scoring system to establish the prognosis. METHODS:We collected baseline clinical, electrophysiologic, and ultrasonographic data from 2 cohorts. The outcomes for all patients were determined on fol...

journal_title：Muscle & nerve

authors： Beekman R,Zijlstra W,Visser LH

更新日期：2017-05-01 00:00:00

abstract：:The role of motor innervation and muscle tension in the posthatching maturation of the slow-tonic anterior latissimus dorsi (ALD) muscle of the chicken has been investigated. Modification of the muscle tension was obtained either by maintaining ALD in a shortened state or by stretching, after or without denervation. I...

journal_title：Muscle & nerve

authors： Gardahaut MF,Rouaud TP,Renaud D,Khaskiye A,Le Douarin GH

更新日期：1989-11-01 00:00:00

abstract：INTRODUCTION:The neuropathy in patients with neurofibromatosis type 2 (NF2) is difficult to quantify and follow up. In this study we compared 3 methods that may help assess motor axon pathology in NF2 patients. METHODS:Nerve conduction studies in median nerves were supplemented by deriving motor unit number estimates ...

journal_title：Muscle & nerve

authors： Farschtschi S,Gelderblom M,Buschbaum S,Bostock H,Grafe P,Mautner VF

更新日期：2017-03-01 00:00:00

abstract：INTRODUCTION:We sought to translate, culturally adapt, and assess the Arabic version of the 15-item myasthenia gravis quality-of-life revised scale (MGQOL15R). METHODS:We assessed reliability with Cronbach α; reproducibility with intraclass correlation coefficient (ICC); validity with Spearman correlations for myasthe...

journal_title：Muscle & nerve

authors： Alanazy MH,Abuzinadah AR,Muayqil T

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Mutations in gap junction protein beta 1 (GJB1) on the X chromosome represent one of the most common causes of hereditary neuropathy. We assessed manifestations associated with a rare 3' untranslated region mutation (UTR) of GJB1 in a large family with X-linked Charcot-Marie-Tooth disease (CMTX). METHODS:...

journal_title：Muscle & nerve

authors： Chen DH,Ma M,Scavina M,Blue E,Wolff J,Karna P,Dorschner MO,Raskind WH,Bird TD

更新日期：2018-05-01 00:00:00

abstract：:We employed physiogenomic analyses to investigate the relationship between myalgia and selected polymorphisms in serotonergic genes, based on their involvement with pain perception and transduction of nociceptive stimuli. We screened 195 hypercholesterolemic, statin-treated patients, all of whom received either atorva...

journal_title：Muscle & nerve

authors： Ruaño G,Thompson PD,Windemuth A,Seip RL,Dande A,Sorokin A,Kocherla M,Smith A,Holford TR,Wu AH

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:Ulnar neuropathy at the elbow (UNE) is a common peripheral compression neuropathy and, in most cases, occurs at 2 sites, the retroepicondylar groove or the cubital tunnel. With regard to a potential therapeutic approach with perineural corticosteroid injection, the aim of this study was to evaluate the dis...

journal_title：Muscle & nerve

authors： Hamscha UM,Tinhofer I,Heber S,Grisold W,Weninger WJ,Meng S

更新日期：2017-08-01 00:00:00

abstract：:Immersion of rat hemidiaphragms in Ca2+-free Krebs solution (KS) containing Ca2+ chelator in vitro leads to separation of basal lamina from the plasma membrane, as well as transient contracture and rapid loss of twitch response [calcium paradox (CP) phase 1]. Subsequent immersion in regular KS results in necrosis of m...

journal_title：Muscle & nerve

authors： Soza M,Karpati G,Carpenter S

更新日期：1986-03-01 00:00:00

abstract：:Several monoclonal antibodies (mcAbs) elicited against the nicotinic acetylcholine receptor (AChR) from Torpedo react also with skeletal muscle AChR. Such mcAbs were used to define antigenic determinants on muscle AChR and to elucidate their effect on muscle AChR functions. Primary chick muscle cultures were used as a...

journal_title：Muscle & nerve

authors： Souroujon MC,Mochly-Rosen D,Gordon AS,Fuchs S

更新日期：1983-05-01 00:00:00

abstract：:Excitability properties were recorded from 14 volunteers following stimulation of the recurrent motor branch of the median nerve in the palm. Distal stimulation resulted in significantly lower strength-duration time constant and lower threshold during prolonged hyperpolarization than did wrist stimulation in the same ...

journal_title：Muscle & nerve

authors： Walters RJ,Kiernan MC,Murray NM,Bostock H

更新日期：2001-12-01 00:00:00

abstract：:Seventy-five consecutive patients with clinical symptoms and signs of meralgia paresthetica underwent bilateral somatosensory evoked potential (SEP) studies involving stimulation of skin areas innervated by the lateral and anterior femoral cutaneous nerves of the thighs. The most common abnormality was an absolute lat...

journal_title：Muscle & nerve

authors： Cordato DJ,Yiannikas C,Stroud J,Halpern JP,Schwartz RS,Akbunar M,Cook M

更新日期：2004-01-01 00:00:00

abstract：INTRODUCTION:Transitioning from adolescence to adulthood can be problematic for individuals with rare disabilities such as muscular dystrophy (MD). METHODS:We identified a cohort of 220 individuals with MD and 440 matched comparison individuals and measured emergency room (ER) and inpatient (IP) encounters for the yea...

journal_title：Muscle & nerve

authors： Mann JR,Royer JA,Mcdermott S,Hardin JW,Ozturk O,Street N

更新日期：2015-11-01 00:00:00

abstract：:Muscle of donor origin was formed after implantation of H-2Kb-tsA58 muscle precursor cells (mpc) into irradiated mdx nu/nu mouse muscles. A series of injections of the myotoxin, notexin, which destroys mature muscle fibers but spares muscle precursor cells and other tissues, was made into the mpc-injected muscles, lea...

journal_title：Muscle & nerve

authors： Gross JG,Morgan JE

更新日期：1999-02-01 00:00:00

abstract：:Frog muscles bathed in solutions equilibrated with 0.5%-2.0% halothane develop large contractures when cooled to 2-4 degrees C. These halothane-cooling contractures (HCC) are dose dependent and reproducible; they are potentiated by lidocaine (5 mM), abolished by procaine (5 mM), and partially inhibited by procainamide...

journal_title：Muscle & nerve

authors： Suarez-Kurtz G,Sudo RT

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Limited data exist regarding myopathies with early or prominent dysphagia. METHODS:A retrospective study was performed (January 2003 to August 2019) to identify myopathy patients in whom dysphagia was the initial symptom or was disproportionately severe compared with limb weakness. RESULTS:Thirty-two patie...

journal_title：Muscle & nerve

authors： Triplett JD,Pinto MV,Hosfield EA,Milone M,Liewluck T

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Psoriasis is a T-cell-mediated skin disorder with uncommon extracutaneous manifestations. Rare patients with psoriasis and myopathy have been reported. METHODS:We conducted a retrospective review of medical records of psoriasis patients seen at the Mayo Clinic during the period from January 1, 1996 to May...

journal_title：Muscle & nerve

authors： Liewluck T,Ernste FC,Tracy JA

更新日期：2013-11-01 00:00:00

abstract：INTRODUCTION:In compressive neuropathies, large myelinated nerve fibers are generally thought to be more susceptible. In this study, we investigated small myelinated Aδ and unmyelinated C fiber function in patients with mild, moderate, and severe carpal tunnel syndrome. METHODS:Forty-four healthy controls and 81 carpa...

journal_title：Muscle & nerve

authors： Clarke C,Christensen C,Curran MWT,Chan KM

更新日期：2017-10-01 00:00:00

abstract：:Patients with chronic inflammatory demyelinating polyneuropathy (CIDP) received immune globulin intravenous, 10% caprylate/chromatography purified (IGIV-C, Gamunex; n=59) or placebo (n=58) every 3 weeks for up to 24 weeks (first period) in a randomized, double-blind, parallel-group, response-conditional, crossover stu...

journal_title：Muscle & nerve

authors： Bril V,Katzberg H,Donofrio P,Banach M,Dalakas MC,Deng C,Hanna K,Hartung HP,Hughes RA,Latov N,Merkies IS,van Doorn PA,ICE Study Group.

更新日期：2009-04-01 00:00:00

abstract：:Morvan's syndrome is a rare disorder characterized by neuromyotonia, hyperhidrosis, and central nervous system dysfunction. We report a patient with features of this syndrome, but who initially presented with breathing difficulties. Concentric needle electromyography showed an abundance of myokymic and neuromyotonic d...

journal_title：Muscle & nerve

authors： Löscher WN,Wanschitz J,Reiners K,Quasthoff S

更新日期：2004-08-01 00:00:00

abstract：INTRODUCTION:We investigated the effects of aerobic and resistance exercise in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). METHODS:Eighteen CIDP patients treated with subcutaneous immunoglobulin performed 12 weeks of aerobic exercise and 12 weeks of resistance exercise after a run-in period...

journal_title：Muscle & nerve

authors： Markvardsen LH,Overgaard K,Heje K,Sindrup SH,Christiansen I,Vissing J,Andersen H

更新日期：2018-01-01 00:00:00

abstract：:Electron microscopic studies of long-term denervated rat muscles have identified very small, immature myofibers that are believed to arise from detached satellite cells that have fused to form new fibers within the interstitial space. At present, it is unknown whether and to what extent equivalent fibers exist in dene...

journal_title：Muscle & nerve

authors： Doppler K,Mittelbronn M,Bornemann A

更新日期：2008-01-01 00:00:00

abstract：:Nerve conduction studies (NCS) may be deferred because of a perceived risk of cardiac arrhythmia in the presence of same-limb peripheral intravenous lines. Patients with implanted pacemakers or defibrillators provide a model in whom this risk can be assessed. Twenty patients, seven with pacemakers and 13 with defibril...

journal_title：Muscle & nerve

authors： Mellion ML,Buxton AE,Iyer V,Almahameed S,Lorvidhaya P,Gilchrist JM

更新日期：2010-08-01 00:00:00