Abstract:
:To elucidate whether the frontal components of scalp somatosensory evoked potentials (SEPs) depend on the type of peripheral input, we compared scalp SEPs in response to electrical stimuli applied to: (i) the proximal phalanx of the thumb, involving both deep and cutaneous afferents; and (ii) the distal phalanx of the thumb, involving cutaneous afferents, but excluding joint inputs coming from the interphalangeal articulation. We applied the same dipolar model that we built to explain the scalp SEP distribution to median nerve stimulation in previous investigations. Cortical SEPs after proximal stimulation were generated by three dipolar sources, one of which was likely to account for the frontal scalp N30. When we analyzed SEPs for distal (purely cutaneous) stimulation, the frontal and central recordings showed a clear reduction in amplitude of the negative responses having a latency of about 30 ms. Moreover, when applying the dipole model derived from analysis of responses to proximal stimulation to SEPs to distal stimulation, the source corresponding to the N30 distribution showed no activity, suggesting a strong relationship between joint and tendinous inputs and the activity of the N30 generator.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Restuccia D,Valeriani M,Barba C,Le Pera D,Tonali P,Mauguière Fdoi
10.1002/(sici)1097-4598(199907)22:7<910::aid-mus15subject
Has Abstractpub_date
1999-07-01 00:00:00pages
910-9issue
7eissn
0148-639Xissn
1097-4598pii
10.1002/(SICI)1097-4598(199907)22:7<910::AID-MUS15journal_volume
22pub_type
杂志文章相关文献
MUSCLE & NERVE文献大全abstract:INTRODUCTION:The aim of this study was to assess age- and gender-specific incidence rates (IRs) of acetylcholine receptor (AChR)-antibody-positive myasthenia gravis (MG) in South Africa, and geographical variations in incidence. METHODS:IRs were calculated from positive AChR-antibody laboratory data between 2011 and 2...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24348
更新日期:2015-04-01 00:00:00
abstract::High-dose immunoglobulins for intravenous administration (IVIg) have originally been developed for substitution therapy in hypogammaglobulinemia. Over the last decade they are increasingly used in the treatment of immune-mediated diseases. In this review the results in immune-mediated neuromuscular diseases are summar...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-4598(199702)20:2<136::aid-mus1>
更新日期:1997-02-01 00:00:00
abstract::L1 radiculopathy is very rare and difficult to diagnose with needle electromyography. A patient presented with pain and hypesthesia on the anterolateral aspect of the left thigh. Nerve conduction studies and needle electromyography were normal, except for the quadratus lumborum and iliopsoas muscles, which showed abno...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21601
更新日期:2010-04-01 00:00:00
abstract::We studied histopathological changes in the biceps brachii muscle in relation to age and the degree of muscle weakness in 64 patients (aged 11-59 years) with myotonic dystrophy. The proportion of type 1 fibers was unaltered in the adolescent patients compared with control values, but increased with age. The average di...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880170911
更新日期:1994-09-01 00:00:00
abstract:INTRODUCTION:While current exercise guidelines recommend progressive, high-intensity resistance training (RT) to promote muscle hypertrophy and strength gains, controversy exists regarding the efficacy of lighter-load RT. We compared 2 work-matched RT interventions that differed in training intensity. METHODS:Fifteen ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24271
更新日期:2015-01-01 00:00:00
abstract::Many post-polio patients develop new muscle weakness decades after the initial illness. However, its mechanism and treatment are controversial. The purpose of this study was to test the hypotheses that: (1) after strength training, post-polio patients show strength improvement comparable to that seen in the healthy el...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/mus.10327
更新日期:2003-03-01 00:00:00
abstract::Comparison was made between simultaneous recordings of the electromyogram (EMG) and acoustic myogram (AMG) signals and the torque produced by the lumbar erectores spinae muscles of three healthy subjects while they performed isometric contractions. Repeatability of each signal was studied. The AMG had a relationship t...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880110409
更新日期:1988-04-01 00:00:00
abstract::Ventricular repolarization dysfunction has recently been reported in multiple sclerosis (MS). We evaluated ventricular repolarization dysfunction in 52 MS patients and looked for a relationship between corrected QT (QTc) abnormalities (i.e., abnormalities of QT intervals corrected for rate) and spinal cord magnetic re...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/1097-4598(200008)23:8<1284::aid-mus21>3.0.
更新日期:2000-08-01 00:00:00
abstract:INTRODUCTION:Amyotrophic lateral sclerosis (ALS) is a debilitating neurologic disorder with poor survival rates and no clear biomarkers for disease diagnosis and prognosis. METHODS:We compared serum microRNA (miRNA) expression from patients with ALS with healthy controls and patients with multiple sclerosis and Alzhei...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26106
更新日期:2018-08-01 00:00:00
abstract::The term thoracic outlet syndrome (TOS) refers to a heterogeneous group of disorders, all of which have in common compression of one or more neurovascular elements at some point within the thoracic outlet. Of the five disorders comprising this group, four have all of the features expected of a syndrome-a recognized co...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.23235
更新日期:2012-06-01 00:00:00
abstract:INTRODUCTION:In mitochondrial disease, it is likely that energy substrate depletion leads to paralysis of ATPase-dependent pumps, resulting in membrane depolarization. Axonal depolarization has been demonstrated in a crisis, but not in the resting state. We, therefore, stressed axons using ischemia to see if this would...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23733
更新日期:2013-05-01 00:00:00
abstract::The aim of this study was to investigate the fasciculation potentials (FPs) in the small-peripheral muscles of the foot and hand and the possible associated factors, in a healthy population. One hundred-twenty-two normal individuals (65 men and 57 women), aged 17-67 years (mean 39.96, SD=12.76) participated in the stu...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199804)21:4<533::aid-mus14
更新日期:1998-04-01 00:00:00
abstract:INTRODUCTION:The distribution of clinical and neurophysiological abnormalities in patients with early amyotrophic lateral sclerosis (ALS) was investigated in an attempt to delineate patterns of disease spread. METHODS:Clinical and electrodiagnostic data were collected from 150 ALS patients and analyzed based on the cl...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24244
更新日期:2014-12-01 00:00:00
abstract::Electrophysiologic detection of the first signs of gastrocnemius muscle reinnervation shows that after a single localized freezing of the rat sciatic nerve, isaxonine does not significantly increase the rate of axonal regeneration. However, this drug does significantly enhance axonal sprouting, as it induces an increa...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880080205
更新日期:1985-02-01 00:00:00
abstract:INTRODUCTION:In this study, we determined normal levels of dysferlin expression in CD14+ monocytes by flow cytometry (FC) as a screening tool for dysferlinopathies. METHODS:Monocytes from 183 healthy individuals and 29 patients were immunolabeled, run on an FACScalibur flow cytometer, and analyzed by FlowJo software. ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25156
更新日期:2016-12-01 00:00:00
abstract::We report the case of a 55-year-old man with non-small-cell lung cancer who underwent radiation, chemotherapy with carbotaxol and paclitaxel, and left upper lobe removal 2 years prior to evaluation. He was referred for disabling orthostatic hypotension (113/69 mm Hg supine and 66/47 mm Hg standing after 10 minutes) wi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21528
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:We aimed to describe the electrophysiological progression rate of chronic idiopathic axonal polyneuropathy (CIAP) and look into the potential role of human leukocyte antigen (HLA) genetic susceptibility in its development. METHODS:We recruited 57 patients with CIAP (mean age at diagnosis 67, mean follow-up ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.27164
更新日期:2021-01-13 00:00:00
abstract::The relationship between motor function and muscle strength in patients with spinal muscular atrophy (SMA) is still controversial. In 120 genetically proven SMA patients, aged 5 years or older, we measured muscle strength in the arms and legs by a hand-held dynamometer, forced vital capacity by a spirometer, and the t...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20018
更新日期:2004-04-01 00:00:00
abstract::The objectives of this study were 1) to determine the degree to which soleus motoneurons find their appropriate target following crush and transection injuries to the sciatic nerve, and 2) to determine whether repair of a transected nerve with a silicone tube leads to greater specificity of reinnervation and recovery ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199701)20:1<29::aid-mus4>3
更新日期:1997-01-01 00:00:00
abstract::The F-wave was used to estimate motor nerve conduction velocity (MNCV) along the proximal segment of the fastest axons of the deep peroneal nerve (anterior-horn cells to knee) in 13 patients with amyotrophic lateral sclerosis (ALS) and in 21 age- and sex-matched control subjects. Measurements were based on the shortes...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880010607
更新日期:1978-11-01 00:00:00
abstract:INTRODUCTION:The radial nerve and posterior interosseous nerve (PIN) are prone to injury at multiple sites. Electrodiagnostic (EDx) studies may only identify the most proximal lesion. Nerve ultrasound could augment EDx by visualizing additional pathology. METHODS:This investigation was a retrospective examination of u...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24778
更新日期:2016-03-01 00:00:00
abstract::Ten adult myotonic dystrophy patients underwent measurements of lung function, maximal dynamic and static ventilatory efforts, and respiratory muscle electromyography (EMG). EMG studies were performed during spontaneous breathing or when subjects breathed through high inspiratory or expiratory resistive loads. Present...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880080708
更新日期:1985-09-01 00:00:00
abstract:INTRODUCTION:Many prognostic factors have been studied in carpal tunnel decompression, but most studies consider only a subset of variables. METHODS:Three thousand three hundred thirty-two operations were used to develop prognostic models, and 885 operations were used for validation. Outcome recorded on a Likert scale...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26297
更新日期:2018-12-01 00:00:00
abstract::Peripheral nerve disorders are commonly encountered in clinical practice. Electrodiagnostic studies remain the cornerstone of the evaluation of nerve disorders. More recently, ultrasound has played an increasing complementary role in the neuromuscular clinic. Ultrasound elastography is a technique that measures the el...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26624
更新日期:2019-11-01 00:00:00
abstract:INTRODUCTION:Despite the existence of guidelines, painful neuropathy is often inappropriately treated. We sought to determine the effectiveness of a clinical decision support system on guideline-recommended medication use. METHODS:We randomized neurology providers, stratified by subspecialty, to a best practice alert ...
journal_title:Muscle & nerve
pub_type: 杂志文章,随机对照试验
doi:10.1002/mus.26774
更新日期:2020-05-01 00:00:00
abstract::A 53-year-old man developed multifocal radicular pain. The diagnosis of Lyme neuroborreliosis was delayed until bifacial paresis and right lower abdominal wall weakness developed, prompting further evaluation. Cerebrospinal fluid (CSF) examination showed aseptic meningitis. Antibodies directed against Borrelia burgdor...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880161118
更新日期:1993-11-01 00:00:00
abstract:INTRODUCTION:Evaluation of nerve mechanical properties has the potential to improve assessment of nerve impairment. Shear wave velocity, as measured by using shear wave (SW) ultrasound elastography, is a promising indicator of nerve mechanical properties such as stiffness. However, elucidation of external factors that ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26842
更新日期:2020-05-01 00:00:00
abstract:INTRODUCTION:We examined the extent to which fatiguing cycling exercise in the heat influences contractile function in modulating the force-frequency relationship. METHODS:Before (∽37.0 °C) and after (∽38.5 °C) exercise (ExH) and passive (PaH) hyperthermia, an 8-s train of stimulation at 10, 20, 50, and 100 Hz (2 s pe...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24228
更新日期:2014-11-01 00:00:00
abstract::The purpose of this study was to determine whether initial muscle length influenced the extent of isometric force deficit following 20 in vitro lengthening contractions of the soleus muscle from Fischer 344 rats. Force deficit was evaluated following one of five protocols: (1) lengthening contractions from optimal mus...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10112
更新日期:2002-06-01 00:00:00
abstract:INTRODUCTION:In this study we investigated the interaction between adipose tissue-derived stem cells (ASCs) and myoblasts in co-culture experiments. METHODS:Specific inductive media were used to differentiate ASCs in vitro into a Schwann cell-like phenotype (differentiated adipose tissue-derived stem cells, or dASCs) ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25741
更新日期:2018-02-01 00:00:00