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Toxic effects of fluoride on organisms.

Abstract：

:Accumulation of excess fluoride in the environment poses serious health risks to plants, animals, and humans. This endangers human health, affects organism growth and development, and negatively impacts the food chain, thereby affecting ecological balance. In recent years, numerous studies focused on the molecular mechanisms associated with fluoride toxicity. These studies have demonstrated that fluoride can induce oxidative stress, regulate intracellular redox homeostasis, and lead to mitochondrial damage, endoplasmic reticulum stress and alter gene expression. This paper reviews the present research on the potential adverse effects of overdose fluoride on various organisms and aims to improve our understanding of fluoride toxicity.

journal_name

Life Sci

journal_title

Life sciences

authors

Zuo H,Chen L,Kong M,Qiu L,Lü P,Wu P,Yang Y,Chen K

doi

10.1016/j.lfs.2018.02.001

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

18-24

eissn

0024-3205

issn

1879-0631

pii

S0024-3205(18)30045-6

journal_volume

198

pub_type

杂志文章,评审

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