Abstract:
Background:Reproductive system cancer is an important cause of morbidity and mortality worldwide which threatens women's health and lives. Breast, cervical, and ovarian cancer have the higher incidence and mortality among a series of gynecology malignant tumor. We aimed to compare and assess the temporal trends of common female malignances on breast, cervical, and ovarian cancer mortality in developed regions of Asia including Japan, Republic of Korea, and Singapore and analyze the detached effects of chronological age, time period, and birth cohort by age-period-cohort (APC) analysis. Methods:The mortality data for these three cancers were collected from the WHO Mortality Database in Japan, Republic of Korea, and Singapore from 1954 to 2013, from 1989 to 2013, and from 1964 to 2013, respectively. We fitted an age-period-cohort model and intrinsic estimator method to estimate the independent effect of each age, time period, and birth cohort on cancer mortality and describe the secular changes in three Asian countries. Results:For the overall trends of breast cancer, the ASMRs of breast cancer showed a general increasing trend among three countries during the study periods while the change pattern in Singapore was different from the rest of the two countries for cervical and ovarian cancer. By APC analysis, the three cancer mortality risks generally increased with age and decreased with birth cohort. For period effects of breast and ovarian cancer, increasing effects with time were observed; however, for period effects of cervical cancer, converse change pattern was presented among three countries. Conclusions:Our study shows that the ASMRs of breast, cervical, and ovarian cancer remain high in Singapore compared to Japan and Korea. Generally speaking, the mortality risk of three cancers increased with age, and period and cohort effects may collectively affect the common female malignances mortality for East Asian women.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Wang J,Lv H,Xue Z,Wang L,Bai Zdoi
10.1155/2018/5307459subject
Has Abstractpub_date
2018-03-21 00:00:00pages
5307459eissn
2314-6133issn
2314-6141journal_volume
2018pub_type
杂志文章abstract:Objectives:Obstructive sleep apnea (OSA) is a common disorder influenced by genetic and environmental factors. Mutations of AT-hook DNA-binding motif containing 1 (AHDC1) gene have been implicated which could cause rare syndromes presenting OSA. This study aims to investigate some rare mutations of AHDC1 in Chinese Han...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/5907361
更新日期:2019-10-13 00:00:00
abstract::A new fungus Cladosporium oxysporum GQ-3 producing extracellular xylanase was isolated from decaying agricultural waste and identified based on the morphology and comparison of internal transcribed spacer (ITS) rDNA gene sequence. C. oxysporum produced maximum xylanase activity of 55.92 U/mL with wheat bran as a subst...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/4575024
更新日期:2016-01-01 00:00:00
abstract::Diabetes has become the third most serious threat to human health, after cancer and cardiovascular disease. Notably, Lactobacillus brevis is the most common species of LAB that produces γ-aminobutyric acid (GABA). The aim of this study is to clarify the effect of time, strain types, antibiotic concentrations, differen...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/7356173
更新日期:2018-09-19 00:00:00
abstract:Background and Aims:The present study aimed to develop a simple and sensitive method for quantitative determination of monocrotaline (MCT) in mouse blood employing ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometry (UPLC-ESI/MS/MS) using rhynchophylline as an internal standard. Me...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1578643
更新日期:2018-08-13 00:00:00
abstract::The VAD (vincristine-doxorubicin-dexamethasone) regimen has been used for decades to treat multiple myeloma (MM). Based on reports that vascular endothelial growth factor- (VEGF-) mediated angiogenesis is critical for MM pathogenesis, the antiangiogenic compound thalidomide has been added to VAD (T-VAD). However, it r...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2018/3936706
更新日期:2018-11-11 00:00:00
abstract::Early recovery from muscular injury is crucial for elite athletes. Hyperbaric oxygen therapy (HBOT) has been reported to be beneficial in terms of accelerating cell recovery and tissue repair, which are considered to be helpful for eliminating fatigue and recovering stamina. This study was performed to evaluate the ef...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2019/6289380
更新日期:2019-05-29 00:00:00
abstract::This study investigated the effects of a pragmatic lifestyle intervention in obese adults with continuous positive airway pressure-treated obstructive sleep apnoea hypopnoea syndrome (OSAHS). Sixty patients were randomised 1 : 1 to either a 12-week lifestyle intervention or an advice-only control group. The interventi...
journal_title:BioMed research international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1155/2014/102164
更新日期:2014-01-01 00:00:00
abstract:Background:Haemonchus contortus, the causative agent of Haemonchosis, is the most economically important parasite in small ruminant production. Control with chemotherapy has not been successful due to rapid emergence of drug-resistant strains. There is a continuous search for alternative leads particularly from plants....
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/1905987
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/981867
更新日期:2014-01-01 00:00:00
abstract::Correlation of parametrized image texture features (ITF) analyses conducted in different regions of interest (ROIs) overcomes limitations and reliably reflects image quality. The aim of this study is to propose a nonparametrical method and classify the quality of a magnetic resonance (MR) image that has undergone cont...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3706581
更新日期:2019-11-20 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/4961768
更新日期:2019-06-06 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3162649
更新日期:2016-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6067583
更新日期:2018-10-24 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/720483
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/607137
更新日期:2013-01-01 00:00:00
abstract::Stem cells are biological cells that can self-renew and can differentiate into multiple cell lineages. Stem cell-based therapy is emerging as a promising alternative therapeutic option for various disorders. Mesenchymal stem cells (MSCs) are multipotent adult stem cells that are isolated from various tissues and can b...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/6104738
更新日期:2019-01-29 00:00:00
abstract::Natural medical plant is considered as a good source of tyrosinase inhibitors. Red vine leaf extract (RVLE) can be applied to a wide variety of medical disciplines, such as treatments for chronic venous insufficiency over many decades. This study investigated the tyrosinase inhibitory activity of RVLE containing galli...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/5232680
更新日期:2017-01-01 00:00:00
abstract::Recombinant adeno-associated virus (AAV) vectors are powerful tools for both basic neuroscience experiments and clinical gene therapies for neurological diseases. Intravascularly administered self-complementary AAV9 vectors can cross the blood-brain barrier. However, AAV9 vectors are of limited usefulness because they...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/974819
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/7058105
更新日期:2018-06-04 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/685426
更新日期:2014-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2017/7865747.]. ...
journal_title:BioMed research international
pub_type: 杂志文章,已发布勘误
doi:10.1155/2018/6348625
更新日期:2018-05-14 00:00:00
abstract::Dengue fever, a reemerging disease, is putting nearly 2.5 billion people at risk worldwide. The number of infections and the geographic extension of dengue fever infection have increased in the past decade. The disease is caused by the dengue virus, a flavivirus that uses mosquitos Aedes sp. as vectors. The disease ha...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/825039
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2016/5959721
更新日期:2016-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/438403
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2020/9526289
更新日期:2020-01-02 00:00:00
abstract::Herein the extraction method of fucoidan from Laminaria japonica is reported. Firstly, chitosan, chitosan-N-2-hydroxypropyl trimethyl ammonium chloride (HACC), and hexadecyltrimethylammonium bromide (CPAB) were used to extract the fucoidan. The results showed that chitosan was the optimal extractant compared with the ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/193689
更新日期:2013-01-01 00:00:00
abstract::Based on low carbon wastewater as the research object and using corncob as an external solid carbon source, the performance of corncob organic matter was assessed for its release potential, quantity of release, and safety of use. The effects of varying quantities of the solid carbon source on simultaneous nitrificatio...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/3691819
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/520763
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/821475
更新日期:2014-01-01 00:00:00
abstract::DNA Primase Subunit 1 (PRIM1) is crucial for cancer development and progression. However, there remains a lack of comprehension concerning the clinical implication of PRIM1 in HCC. Here, aberrant expression of PRIM1 was identified in HCC according to available databases. The prognostic value of PRIM1 in patients prese...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9689312
更新日期:2020-08-22 00:00:00