Suppression of the translation defect phenotype specific for a virus-associated RNA-deficient adenovirus mutant in monkey cells by simian virus 40.

abstract：:We have obtained a polyclonal antiserum, N-BE, against the denatured, amino-terminal half of the measles virus (MV) nucleocapsid (N) protein and a monoclonal antibody (MAb), N46, which recognizes a conformation-dependent epitope in the same region. Amino acid residues 23 to 239 were required and sufficient for the for...

journal_title：Journal of virology

authors： Gombart AF,Hirano A,Wong TC

更新日期：1993-07-01 00:00:00

abstract：:Noninfectious spikeless particles have been obtained from vesicular stomatitis virus (VSV, Indiana serotype) by bromelain or Pronase treatment. They lack the viral glycoprotein (G) but contain all the other viral components (RNA, lipid, and other structural proteins). Triton-solubilized VSV-Indiana glycoprotein prepar...

journal_title：Journal of virology

authors： Bishop DH,Repik P,Obijeski JF,Moore NF,Wagner RR

更新日期：1975-07-01 00:00:00

abstract：:A human cell line (293) transformed by adenovirus type 5 encodes mRNA's and proteins from the early region 1 (E1) of the viral genome. These products correspond to those synthesized early after adenovirus infection of normal cells. This pattern of expression is different from that observed at later times in the lytic ...

journal_title：Journal of virology

authors： Spector DJ,Halbert DN,Raskas HJ

更新日期：1980-12-01 00:00:00

abstract：:Fine structure marker rescue involving the use of subfragments of vaccinia virus HindIII DNA fragments L, J, and H has been used to map the mutations in eight temperature-sensitive mutants of vaccinia virus representing four complementation groups. Comparison of their map locations with the positions of the open readi...

journal_title：Journal of virology

authors： Ensinger MJ,Weir JP,Moss B

更新日期：1985-12-01 00:00:00

abstract：:Retroviral integrases associate during the early viral life cycle with preintegration complexes that catalyze the integration of reverse-transcribed viral cDNA into the host chromosomes. Several cellular and viral proteins have been reported to be incorporated in the preintegration complex. This study demonstrates tha...

journal_title：Journal of virology

authors： Inayoshi Y,Okino Y,Miyake K,Mizutani A,Yamamoto-Kishikawa J,Kinoshita Y,Morimoto Y,Imamura K,Morshed M,Kono K,Itoh T,Nishijima K,Iijima S

更新日期：2010-08-01 00:00:00

abstract：:Borna disease virus (BDV) is a nonsegmented, negative-strand RNA virus that causes neurological diseases in a variety of warm-blooded animal species. There is general consensus that BDV can also infect humans, being a possible zoonosis. Although the clinical consequences of human BDV infection are still controversial,...

journal_title：Journal of virology

authors： Bajramovic JJ,Syan S,Brahic M,de la Torre JC,Gonzalez-Dunia D

更新日期：2002-06-01 00:00:00

abstract：:The interrelationship of viral ribonucleic acid (RNA) and protein synthesis in cells infected by Sindbis virus was investigated. When cultures were treated with puromycin early in the course of infection, the synthesis of interjacent RNA (26S) was preferentially inhibited. A similar result was obtained by shifting cel...

journal_title：Journal of virology

authors： Scheele CM,Pfefferkorn ER

更新日期：1969-08-01 00:00:00

abstract：:The objective of this investigation was to examine by electron microscopy the replicative ribonucleoprotein (RNP) structures synthesized in vesicular stomatitis virus-infected HeLa cells. Pulse-labeled in vivo products of vesicular stomatitis virus replication and transcription can be separated by centrifugation in Re...

journal_title：Journal of virology

authors： Naeve CW,Summers DF

更新日期：1980-06-01 00:00:00

abstract：:The induction of alpha/beta interferon (IFN-alpha/beta) genes constitutes one of the first responses of the cell to virus infection. The IFN-beta gene is constitutively repressed in uninfected cells and is transiently activated after virus infection. In this work we demonstrate that histone deacetylation regulates the...

journal_title：Journal of virology

authors： Shestakova E,Bandu MT,Doly J,Bonnefoy E

更新日期：2001-04-01 00:00:00

abstract：:The regressing and conventional strains of Friend virus were compared by neutralization assays, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and tryptic peptide mapping of the individual viral components. Neutralization rates of the two viruses differed in the presence of monospecific anti-gp70 antiserum...

journal_title：Journal of virology

authors： Furmanski P,Longley C,Bolles CS,Hines DL,Dietz M

更新日期：1980-03-01 00:00:00

abstract：:By marker rescue with cloned herpes simplex virus 2 DNA fragments, we have mapped the temperature-sensitive mutations of a series of herpes simplex virus 2 mutants to a region of the herpes simplex virus 2 genome that lies within or near the coding sequences for the major DNA-binding protein, ICP8. In cells infected w...

journal_title：Journal of virology

authors： Spang AE,Godowski PJ,Knipe DM

更新日期：1983-01-01 00:00:00

abstract：:Transmission of arenaviruses from rodent hosts to humans is generally thought to occur through inhalation or ingestion of dust or droplets containing viral particles. Here we demonstrate that two identified arenavirus receptors, alpha-dystroglycan (alpha-DG) and transferrin receptor 1 (TfR1), are expressed in polarize...

journal_title：Journal of virology

authors： Dylla DE,Michele DE,Campbell KP,McCray PB Jr

更新日期：2008-06-01 00:00:00

abstract：:Bicistronic RNAs containing the 373-nucleotide-long 5' nontranslated region (NTR) of the classical swine fever virus (CSFV) genome as intercistronic spacer were used to show the presence of an internal ribosome entry site (IRES) in the 5' end of the CSFV genome. By coexpression of the poliovirus 2A protease it was dem...

journal_title：Journal of virology

authors： Rijnbrand R,van der Straaten T,van Rijn PA,Spaan WJ,Bredenbeek PJ

更新日期：1997-01-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome (PRRS) consistently elevates the frequency of disease and mortality in young pigs. Many different secondary bacterial diseases occur in PRRS virus (PRRSV)-infected pigs. However, to date, establishing a reproducible experimental model of PRRSV infection in weaned pigs, wit...

journal_title：Journal of virology

authors： Feng W,Laster SM,Tompkins M,Brown T,Xu JS,Altier C,Gomez W,Benfield D,McCaw MB

更新日期：2001-05-01 00:00:00

abstract：UNLABELLED:The interferon (IFN)-mediated antiviral response is a central aspect of host defense; however, viruses have evolved multiple strategies to counteract IFN-mediated responses in order to successfully infect the host. Herpes simplex virus 1 (HSV-1), a typical human-restricted DNA virus, is capable of counteract...

journal_title：Journal of virology

authors： Zhang D,Su C,Zheng C

更新日期：2016-05-27 00:00:00

abstract：:Nonhuman primates are widely used to study correlates of protective immunity in AIDS research. Successful cellular immune responses have been difficult to identify because heterogeneity within macaque major histocompatibility complex (MHC) genes results in quantitative and qualitative differences in immune responses. ...

journal_title：Journal of virology

authors： Wiseman RW,Wojcechowskyj JA,Greene JM,Blasky AJ,Gopon T,Soma T,Friedrich TC,O'Connor SL,O'Connor DH

更新日期：2007-01-01 00:00:00

abstract：:We previously reported that a recombinant pantothenate auxotroph of Mycobacterium bovis BCG expressing human immunodeficiency virus type 1 (HIV-1) subtype C Gag (rBCGpan-Gag) efficiently primes the mouse immune system for a boost with a recombinant modified vaccinia virus Ankara (rMVA) vaccine. In this study, we furth...

journal_title：Journal of virology

authors： Chege GK,Burgers WA,Stutz H,Meyers AE,Chapman R,Kiravu A,Bunjun R,Shephard EG,Jacobs WR Jr,Rybicki EP,Williamson AL

更新日期：2013-05-01 00:00:00

abstract：:Recombinant myxoma virus (MYXV) can be produced without a loss of infectivity, and its highly specific host range makes it an ideal vaccine vector candidate, although careful examination of its interaction with the immune system is necessary. Similar to rabbit bone marrow-derived dendritic cells (BM-DCs), ovine dendri...

journal_title：Journal of virology

authors： Top S,Foulon E,Pignolet B,Deplanche M,Caubet C,Tasca C,Bertagnoli S,Meyer G,Foucras G

更新日期：2011-12-01 00:00:00

abstract：:Human T-cell lymphotropic virus type 1 (HTLV-1) enhances the growth of T lymphocytes, allowing the generation of T-lymphocyte cell lines. This report describes a limiting-dilution assay system which uses low input numbers of HTLV-1-producing cells for generation of T-lymphocyte cultures. The HTLV-1 transformants gener...

journal_title：Journal of virology

authors： Persaud D,Muñoz JL,Tarsis SL,Parks ES,Parks WP

更新日期：1995-10-01 00:00:00

abstract：:Natural evolution in primate lentiviral reverse transcriptase (RT) appears to have been constrained by the necessity to maintain function within an asymmetric protein composed of two identical primary amino acid sequences (66 kDa), of which one is cleaved (51 kDa). In this study, a detailed phylogenetic analysis now s...

journal_title：Journal of virology

authors： Tebit DM,Lobritz M,Lalonde M,Immonen T,Singh K,Sarafianos S,Herchenröder O,Kräusslich HG,Arts EJ

更新日期：2010-10-01 00:00:00

abstract：:Reassortant viruses which possessed the hemagglutinin and neuraminidase genes of wild-type human influenza A viruses and the remaining six RNA segments (internal genes) of the avian A/Pintail/Alberta/119/79 (H4N6) virus were previously found to be attenuated in humans. To study the genetic basis of this attenuation, w...

journal_title：Journal of virology

authors： Snyder MH,Buckler-White AJ,London WT,Tierney EL,Murphy BR

更新日期：1987-09-01 00:00:00

abstract：:Severe acute respiratory syndrome (SARS) is a highly contagious and life threatening disease, with a fatality rate of almost 10%. The etiologic agent is a novel coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV), with animal reservoirs found in bats and other wild animals and thus the possibility of...

journal_title：Journal of virology

authors： Oh HL,Chia A,Chang CX,Leong HN,Ling KL,Grotenbreg GM,Gehring AJ,Tan YJ,Bertoletti A

更新日期：2011-10-01 00:00:00

abstract：:Canine distemper virus attachment (hemagglutinin [H] equivalent) and fusion (F) antigens were purified by affinity chromatography with monoclonal antibodies. The purified antigens were used to immunize groups of three dogs. Radioimmune precipitation assays with sera from these animals showed that the F antigen prepara...

journal_title：Journal of virology

authors： Norrby E,Utter G,Orvell C,Appel MJ

更新日期：1986-05-01 00:00:00

abstract：:Treatment of cells with lectins specific for N-acetylglucosamine (GlcNAc) blocked infection by mouse cytomegalovirus (MCMV), and GlcNAc pretreatment of the lectin blocked this effect. MCMV failed to infect N-acetylglucosaminidase (GlcNAcase)-treated mouse embryo fibroblasts (MEF). GlcNAc and GlcNAc-containing syntheti...

journal_title：Journal of virology

authors： Ravindranath RM,Graves MC

更新日期：1990-11-01 00:00:00

abstract：:The epithelium plays a key role in the spread of Lassa virus. Transmission from rodents to humans occurs mainly via inhalation or ingestion of droplets, dust, or food contaminated with rodent urine. Here, we investigated Lassa virus infection in cultured epithelial cells and subsequent release of progeny viruses. We s...

journal_title：Journal of virology

authors： Schlie K,Maisa A,Freiberg F,Groseth A,Strecker T,Garten W

更新日期：2010-04-01 00:00:00

abstract：:Human T-cell leukemia virus type 1 (HTLV-1) encodes a 40-kDa Tax phosphoprotein. Tax is a transcriptional activator which modulates expression of the viral long terminal repeat and transcription of many cellular genes. Because Tax is a critical HTLV-1 factor which mediates viral transformation of T cells during the ge...

journal_title：Journal of virology

authors： Peloponese JM Jr,Iha H,Yedavalli VR,Miyazato A,Li Y,Haller K,Benkirane M,Jeang KT

更新日期：2004-11-01 00:00:00

abstract：:Foot-and-mouth disease virus (FMDV) nonstructural protein 3A plays important roles in virus replication, virulence, and host range. In other picornaviruses, homodimerization of 3A has been shown to be relevant for its biological activity. In this work, FMDV 3A homodimerization was evidenced by an in situ protein fluor...

journal_title：Journal of virology

authors： González-Magaldi M,Postigo R,de la Torre BG,Vieira YA,Rodríguez-Pulido M,López-Viñas E,Gómez-Puertas P,Andreu D,Kremer L,Rosas MF,Sobrino F

更新日期：2012-10-01 00:00:00

abstract：:In this study, we characterized the viral determinants of coreceptor usage in relation to susceptibility to antibody-mediated neutralization or enhancement of infectivity by using chimeras of three highly related human immunodeficiency virus type 1 (HIV-1) isolates of different phenotypes. We found that the V3 region ...

journal_title：Journal of virology

authors： Guillon C,Schutten M,Boers PH,Gruters RA,Osterhaus AD

更新日期：2002-03-01 00:00:00

abstract：:Rubella virus contains three structural proteins, capsid, E2, and E1. E2 and E1 are type I membrane glycoproteins that form a heterodimer in the endoplasmic reticulum (ER) before they are transported to and retained in the Golgi complex, where virus assembly occurs. The bulk of unassembled E2 and E1 subunits are not t...

journal_title：Journal of virology

authors： Hobman TC,Lemon HF,Jewell K

更新日期：1997-10-01 00:00:00

abstract：:Small aggregates of viral antigen were encountered in the nuclear matrix. The capsids did not tag with antibodies specific for the virus or for the host cell. This observation remains unexplained. Nuclear and cytoplasmic membranes, as well as the envelope of the virus, reacted with both types of antibodies and appear,...

journal_title：Journal of virology

authors： Nii S,Morgan C,Rose HM,Hsu KC

更新日期：1968-10-01 00:00:00