Spontaneous regression of Friend virus-induced erythroleukemia. VI. Structural and antigenic differences between the regressing and conventional strains of virus.

abstract：:The 104-S monoclonal antibody immunoprecipitated from herpes simplex virus type 2 (HSV-2)-infected cell extracts the 75,000-molecular-weight glycoprotein gF and its 65,000-molecular-weight precursor (pgF). The precursor pgF was sensitive to endoglycosidase H digestion, indicating the presence of high mannose-type olig...

journal_title：Journal of virology

authors： Zweig M,Showalter SD,Bladen SV,Heilman CJ Jr,Hampar B

更新日期：1983-07-01 00:00:00

abstract：:Recently, self-replicating and self-limiting RNA vaccines (RNA replicons) have emerged as an important form of nucleic acid vaccines. Self-replicating RNA eventually causes lysis of transfected cells and does not raise the concern associated with naked DNA vaccines of integration into the host genome. This is particul...

journal_title：Journal of virology

authors： Cheng WF,Hung CH,Chai CY,Hsu KF,He L,Ling M,Wu TC

更新日期：2001-03-01 00:00:00

abstract：:Interferon (IFN) is an important immune system molecule capable of inducing an antiviral state within cells. Herpes simplex virus type 1 (HSV-1) replication is somewhat reduced in tissue culture in the presence of IFN, presumably due to decreased viral transcription. Here, we show mutations that inactivate immediate-e...

journal_title：Journal of virology

authors： Mossman KL,Saffran HA,Smiley JR

更新日期：2000-02-01 00:00:00

abstract：:Rift Valley fever virus strain MP-12 was generated by serial plaque passages of parental strain ZH548 12 times in MRC-5 cells in the presence of a chemical mutagen, 5-fluorouracil. As a result, MP-12 encoded 4, 9, and 10 mutations in the S, M, and L segments, respectively. Among them, mutations in the M and L segments...

journal_title：Journal of virology

authors： Lokugamage N,Freiberg AN,Morrill JC,Ikegami T

更新日期：2012-12-01 00:00:00

abstract：:Infectious cDNA clones of mild (CHV1-Euro7) and severe (CHV1-EP713) hypovirus strains responsible for virulence attenuation (hypovirulence) of the chestnut blight fungus Cryphonectria parasitica were used to construct viable chimeric viruses. Differences in virus-mediated alterations of fungal colony morphology, growt...

journal_title：Journal of virology

authors： Chen B,Geletka LM,Nuss DL

更新日期：2000-08-01 00:00:00

abstract：:A covalently closed circular form of unintegrated viral DNA obtained from NIH 3T3 cells freshly infected with Moloney murine leukemia virus (M-MLV) and a port of the endogenous M-MLV from the BALB/Mo mouse strain have been cloned in bacteriophage lambda. The unintegrated viral DNA was cleaved with restriction endonucl...

journal_title：Journal of virology

authors： Berns AJ,Lai MH,Bosselman RA,McKennett MA,Bacheler LT,Fan H,Maandag EC,van der Putten HV,Verma IM

更新日期：1980-10-01 00:00:00

abstract：:Recombinant retroviruses containing the trans activator genes of human T-cell leukemia virus (HTLV) type II and human T-cell lymphotropic virus type III were constructed. The trans activator genes tat II and tat III were inserted into the murine retroviral vector pZIPNEOSV(X)1. Recombinant plasmids were transfected in...

journal_title：Journal of virology

authors： Rosen CA,Sodroski JG,Campbell K,Haseltine WA

更新日期：1986-01-01 00:00:00

abstract：:We have previously demonstrated that the human papillomavirus (HPV) genome replicates effectively in U2OS cells after transfection using electroporation. The transient extrachromosomal replication, stable maintenance, and late amplification of the viral genome could be studied for high- and low-risk mucosal and cutane...

journal_title：Journal of virology

authors： Reinson T,Toots M,Kadaja M,Pipitch R,Allik M,Ustav E,Ustav M

更新日期：2013-01-01 00:00:00

abstract：:The mammalian APOBEC3 family of cytidine deaminases includes members that can act as potent inhibitors of retroviral infectivity and retrotransposon mobility. Here, we have examined whether the alpharetrovirus Rous sarcoma virus (RSV) is susceptible to inhibition by a range of human APOBEC3 proteins. We report that RS...

journal_title：Journal of virology

authors： Wiegand HL,Cullen BR

更新日期：2007-12-01 00:00:00

abstract：:Yellow fever virus (YFV), a member of the Flavivirus genus, has a plus-sense RNA genome encoding a single polyprotein. Viral protein NS3 includes a protease and a helicase that are essential to virus replication and to RNA capping. The 1.8-A crystal structure of the helicase region of the YFV NS3 protein includes resi...

journal_title：Journal of virology

authors： Wu J,Bera AK,Kuhn RJ,Smith JL

更新日期：2005-08-01 00:00:00

abstract：:The human immunodeficiency virus (HIV) Tat protein has a critical role in viral transcription, but this study focuses on its additional role as an extracellular effector of lymphocyte cell death. It is well known that Tat induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL) in peripheral blood mononu...

journal_title：Journal of virology

authors： Yang Y,Tikhonov I,Ruckwardt TJ,Djavani M,Zapata JC,Pauza CD,Salvato MS

更新日期：2003-06-01 00:00:00

abstract：:The human immunodeficiency virus type 1 (HIV-1) epidemic in Southeast Asia has been largely due to the emergence of clade E (HIV-1E). It has been suggested that HIV-1E is derived from a recombinant lineage of subtype A (HIV-1A) and subtype E, with multiple breakpoints along the E genome. We obtained complete genome se...

journal_title：Journal of virology

authors： Anderson JP,Rodrigo AG,Learn GH,Madan A,Delahunty C,Coon M,Girard M,Osmanov S,Hood L,Mullins JI

更新日期：2000-11-01 00:00:00

abstract：UNLABELLED:Intron-containing mRNAs are subject to restricted nuclear export in higher eukaryotes. Retroviral replication requires the nucleocytoplasmic transport of both spliced and unspliced RNA transcripts, and RNA export mechanisms of gammaretroviruses are poorly characterized. Here, we report the involvement of the...

journal_title：Journal of virology

authors： Sakuma T,Davila JI,Malcolm JA,Kocher JP,Tonne JM,Ikeda Y

更新日期：2014-04-01 00:00:00

abstract：:The retroviral Gag precursor plays an important role in the assembly of virion particles. The capsid (CA) protein of the Gag molecule makes a major contribution to this process. In the crystal structure of the free CA protein of the human immunodeficiency virus type 1 (HIV-1), 11 residues of the C terminus were found ...

journal_title：Journal of virology

authors： Melamed D,Mark-Danieli M,Kenan-Eichler M,Kraus O,Castiel A,Laham N,Pupko T,Glaser F,Ben-Tal N,Bacharach E

更新日期：2004-09-01 00:00:00

abstract：:To investigate the relation between the polyoma tumor-specific transplantation antigen and the virus-coded proteins, mice were immunized by inoculation of a variety of viable polyoma virus mutants and then challenged with polyoma virus-induced tumors. Two classes of early region mutants were used. One class produces a...

journal_title：Journal of virology

authors： Dalianis T,Magnusson G,Ito Y,Klein G

更新日期：1982-09-01 00:00:00

abstract：:Human bocavirus (HBoV) is a newly discovered parvovirus associated with acute respiratory tract illness (ARTI) and gastrointestinal illness. No previous reports indicated the presence of HBoV infection in Jiangsu Province, China. Here we report three complete genomic sequences of HBoV strains from children with gastro...

journal_title：Journal of virology

authors： Wang X,Zhang X,Tian H,Ling F,Yu M,Sun G,Yang S,Shen Q,Wang Y,Shao S,Zhang W

更新日期：2012-12-01 00:00:00

abstract：:The family of giant viruses is still expanding, and evidence of a translational machinery is emerging in the virosphere. The Klosneuvirinae group of giant viruses was first reconstructed from in silico studies, and then a unique member was isolated, Bodo saltans virus. Here we describe the isolation of a new member in...

journal_title：Journal of virology

authors： Bajrai LH,Mougari S,Andreani J,Baptiste E,Delerce J,Raoult D,Azhar EI,La Scola B,Levasseur A

更新日期：2019-12-12 00:00:00

abstract：:Satellite RNAs are the smallest infectious agents whose replication is thought to be completely dependent on their helper virus (HV). Here we report that, when expressed autonomously in the absence of HV, a variant of satellite RNA (satRNA) associated with Cucumber mosaic virus strain Q (Q-satRNA) has a propensity to ...

journal_title：Journal of virology

authors： Choi SH,Seo JK,Kwon SJ,Rao AL

更新日期：2012-05-01 00:00:00

abstract：:Naked DNA vaccines expressing the prM and E genes of two tick-borne flaviviruses, Russian spring summer encephalitis (RSSE) virus and Central European encephalitis (CEE) virus were evaluated in mice. The vaccines were administered by particle bombardment of DNA-coated gold beads by Accell gene gun inoculation. Two imm...

journal_title：Journal of virology

authors： Schmaljohn C,Vanderzanden L,Bray M,Custer D,Meyer B,Li D,Rossi C,Fuller D,Fuller J,Haynes J,Huggins J

更新日期：1997-12-01 00:00:00

abstract：:Like other herpesviruses, Kaposi's sarcoma-associated herpesvirus (KSHV, also designated human herpesvirus 8) can establish a latent infection in the infected host. During latency a small number of genes are expressed. One of those genes encodes latency-associated nuclear antigen (LANA), which is constitutively expres...

journal_title：Journal of virology

authors： Lan K,Kuppers DA,Verma SC,Robertson ES

更新日期：2004-06-01 00:00:00

abstract：:We analyzed xenotropic murine leukemia virus-related virus (XMRV) integration site sequences previously identified from human prostate tissues for single-nucleotide polymorphisms (SNPs) to discriminate between patient and potential cell line sources of the proviruses. The SNPs of two integration sites were identical t...

journal_title：Journal of virology

authors： Rusmevichientong A,Das Gupta J,Elias PS,Silverman RH,Chow SA

更新日期：2011-12-01 00:00:00

abstract：:Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA-2) is a key determinant in the EBV-driven B-cell growth transformation process. By activating an array of viral and cellular target genes, EBNA-2 initiates a cascade of events which ultimately cause cell cycle entry and the proliferation of the infected B cell. In order...

journal_title：Journal of virology

authors： Maier S,Staffler G,Hartmann A,Höck J,Henning K,Grabusic K,Mailhammer R,Hoffmann R,Wilmanns M,Lang R,Mages J,Kempkes B

更新日期：2006-10-01 00:00:00

abstract：:Extrachromosomal DNA purified from mink cells acutely infected with the Snyder-Theilen strain of feline sarcoma virus (FeSV) was digested with restriction endonucleases, and the DNA fragments were electrophoretically separated, transferred to a solid substrate, and hybridized with radiolabeled DNA transcripts compleme...

journal_title：Journal of virology

authors： Sherr CJ,Fedele LA,Donner L,Turek LP

更新日期：1979-12-01 00:00:00

abstract：:Turkeys inoculated with spleen extracts from lymphoproliferative disease (LPD)-affected birds developed viremia, followed by typical LPD lesions. Electron microscopy and biochemical characterization established that the virus present in the blood of infected turkeys is a type C retrovirus. The viral particles possess ...

journal_title：Journal of virology

authors： Yaniv A,Gazit A,Ianconescu M,Perk K,Aizenberg B,Zimber A

更新日期：1979-04-01 00:00:00

abstract：:Nucleocapsids were isolated from purified enveloped nucleocapsids of Plodia interpunctella granulosis virus by treatment with Nonidet P-40. When analyzed on sodium dodecyl sulfate-polyacrylamide gels, the nucleocapsids consisted of eight polypeptides. One of these, a major component with a molecular weight of 12,500 (...

journal_title：Journal of virology

authors： Tweeten KA,Bulla LA,Consigli RA

更新日期：1980-02-01 00:00:00

abstract：:H.-H. Lu and E. Wimmer (Proc. Natl. Acad. Sci. USA 93:1412-1417, 1996) have demonstrated that the internal ribosomal entry site (IRES) of poliovirus (PV) can be functionally replaced by the related genetic element from hepatitis C virus (HCV). One important finding of this study was that open reading frame sequences 3...

journal_title：Journal of virology

authors： Zhao WD,Wimmer E,Lahser FC

更新日期：1999-02-01 00:00:00

abstract：:The in vitro transcription pattern of simian virus 40 (SV40) deoxyribonucleic acid (DNA) by a mammalian ribonucleic acid (RNA) polymerase, was studied by electron microscopy and velocity sedimentation techniques. It was found that (i) the majority of supercoiled SV40 DNA molecules displayed a single binding site for t...

journal_title：Journal of virology

authors： Herzberg M,Winocour E

更新日期：1970-11-01 00:00:00

abstract：:The biologically relevant form of the human immunodeficiency virus type 1 (HIV-1) envelope (Env) glycoprotein is oligomeric, with the major points of contact between oligomeric partners located in the ectodomain of gp41. To identify and map conserved epitopes and regions in gp41 where structure is influenced by quater...

journal_title：Journal of virology

authors： Earl PL,Broder CC,Doms RW,Moss B

更新日期：1997-04-01 00:00:00

abstract：:ISG15, a 15-kDa interferon-induced protein that participates in antiviral defenses of mammals, is highly conserved among vertebrates. In fish, as in mammals, viral infection and interferon treatment induce isg15 expression. The two ubiquitin-like domains of ISG15 and the presence of a consensus LRLRGG sequence in the ...

journal_title：Journal of virology

authors： Langevin C,van der Aa LM,Houel A,Torhy C,Briolat V,Lunazzi A,Harmache A,Bremont M,Levraud JP,Boudinot P

更新日期：2013-09-01 00:00:00

abstract：:We have previously described several helper independent vector constructions (S. Hughes and E. Kosik, Virology 136:89-99, 1984; J. Sorge and S. H. Hughes, J. Mol. Appl. Genet. 1:547-599, 1982; J. Sorge, B. Ricci, and S. Hughes, J. Virol. 48:667-675, 1983), all of which derive from Rous sarcoma virus. In this report we...

journal_title：Journal of virology

authors： Hughes SH,Greenhouse JJ,Petropoulos CJ,Sutrave P

更新日期：1987-10-01 00:00:00