Pharmacologically evoked apnoeas. Receptors and nervous pathways involved.

Abstract:

:This review analyses the knowledge about the incidence of transient apnoeic spells, induced by substances which activate vagal chemically sensitive afferents. It considers the specificity and expression of appropriate receptors, and relevant research on pontomedullary circuits contributing to a cessation of respiration. Insight is gained into an excitatory drive of 5-HT1A serotonin receptors in overcoming opioid-induced respiratory inhibition.

journal_name

Life Sci

journal_title

Life sciences

authors

Szereda-Przestaszewska M,Kaczyńska K

doi

10.1016/j.lfs.2018.12.021

subject

Has Abstract

pub_date

2019-01-15 00:00:00

pages

237-242

eissn

0024-3205

issn

1879-0631

pii

S0024-3205(18)30804-X

journal_volume

217

pub_type

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