A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models.

abstract：:Growth and remodeling in the heart is driven by a combination of mechanical and hormonal signals that produce different patterns of growth in response to exercise, pregnancy, and various pathologies. In particular, increases in afterload lead to concentric hypertrophy, a thickening of the walls that increases the cont...

journal_title：Biomechanics and modeling in mechanobiology

authors： Estrada AC,Yoshida K,Saucerman JJ,Holmes JW

更新日期：2020-09-24 00:00:00

abstract：:Intracellular calcium dynamics plays an important role in the regulation of vascular endothelial cellular functions. In order to probe the intracellular calcium dynamic response under synergistic effect of wall shear stress (WSS) and adenosine triphosphate (ATP) signals, a novel microfluidic device, which provides the...

journal_title：Biomechanics and modeling in mechanobiology

authors： Chen ZZ,Yuan WM,Xiang C,Zeng DP,Liu B,Qin KR

更新日期：2019-02-01 00:00:00

abstract：:The present study examines the possibility of attenuating blood pulses by means of introducing prosthetic viscoelastic materials able to absorb energy and damp such pulses. Vascular prostheses made of polymeric materials modify the mechanical properties of blood vessels. The effect of these materials on the blood puls...

journal_title：Biomechanics and modeling in mechanobiology

authors： Menacho J,Rotllant L,Molins JJ,Reyes G,García-Granada AA,Balcells M,Martorell J

更新日期：2018-04-01 00:00:00

abstract：:The compliance of the proximal aortic wall is a major determinant of cardiac afterload. Aortic compliance is often estimated based on cross-sectional area changes over the pulse pressure, under the assumption of a negligible longitudinal stretch during the pulse. However, the proximal aorta is subjected to significant...

journal_title：Biomechanics and modeling in mechanobiology

authors： Pagoulatou SZ,Ferraro M,Trachet B,Bikia V,Rovas G,Crowe LA,Vallée JP,Adamopoulos D,Stergiopulos N

更新日期：2020-07-31 00:00:00

abstract：:Computational models of the heart have reached a level of maturity that enables sophisticated patient-specific simulations and hold potential for important applications in diagnosis and therapy planning. However, such clinical use puts strict demands on the reliability and accuracy of the models and requires the sensi...

journal_title：Biomechanics and modeling in mechanobiology

authors： Campos JO,Sundnes J,Dos Santos RW,Rocha BM

更新日期：2019-10-01 00:00:00

abstract：:A predictive Lagrangian-Eulerian finite element eye model was used to analyze 2.27 and 0.45 kg trinitrotoluene equivalent blasts detonated from 24 different locations. Free air and ground level blasts were simulated directly in front of the eye and at lateral offset locations with box, average, less protective, and mo...

journal_title：Biomechanics and modeling in mechanobiology

authors： Weaver AA,Stitzel SM,Stitzel JD

更新日期：2017-04-01 00:00:00

abstract：:An efficient solver for large-scale linear [Formula: see text] simulations was extended for nonlinear material behavior. The material model included damage-based tissue degradation and fracture. The new framework was applied to 20 trabecular biopsies with a mesh resolution of [Formula: see text]. Suitable material par...

journal_title：Biomechanics and modeling in mechanobiology

authors： Stipsitz M,Zysset PK,Pahr DH

更新日期：2020-06-01 00:00:00

abstract：:Past research into brain injury biomechanics has focussed on short duration impulsive events as opposed to the oscillatory loadings associated with Shaken Baby Syndrome (SBS). A series of 2D finite element models of an axial slice of the infant head were created to provide qualitative information on the behaviour of t...

journal_title：Biomechanics and modeling in mechanobiology

authors： Couper Z,Albermani F

更新日期：2008-04-01 00:00:00

abstract：:By following the common definition of forward-dynamics simulations, i.e. predicting movement based on (neural) muscle activity, this work describes, for the first time, a forward-dynamics simulation framework of a musculoskeletal system, in which all components are represented as continuous, three-dimensional, volumet...

journal_title：Biomechanics and modeling in mechanobiology

authors： Röhrle O,Sprenger M,Schmitt S

更新日期：2017-06-01 00:00:00

abstract：:In this study, we hypothesized that spatial relationships exist between the local mechanical environment and inflammatory marker expression in atherosclerotic plaques, and that these relationships are plaque-progression dependent. Histologic cross-sections were collected at regular intervals along the length of diseas...

journal_title：Biomechanics and modeling in mechanobiology

authors： Hallow KM,Taylor WR,Rachev A,Vito RP

更新日期：2009-12-01 00:00:00

abstract：:To investigate the relationship between cellular microelasticity and the structural features of cytoskeletons (CSKs), a microindentation test for apical cell membranes and observation of the spatio-distribution of actin CSKs of fibroblasts were performed by fluorescence and atomic force microscopy (FM/AFM). The indent...

journal_title：Biomechanics and modeling in mechanobiology

authors： Kidoaki S,Matsuda T,Yoshikawa K

更新日期：2006-11-01 00:00:00

abstract：:Continuum mechanical tools are used to describe the deformation, energy density, and material symmetry of a lipid bilayer with spontaneous curvature. In contrast to conventional approaches in which lipid bilayers are modeled by material surfaces, here we rely on a three-dimensional approach in which a lipid bilayer is...

journal_title：Biomechanics and modeling in mechanobiology

authors： Maleki M,Seguin B,Fried E

更新日期：2013-10-01 00:00:00

abstract：:Micro-indentation is a new experimental approach to assess physical cellular properties. Here we attempt to quantify the contribution of geometrical parameters to a cylindrical plant cell's resistance to lateral deformation. This information is important to correctly interpret data obtained from experiments using the ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Bolduc JE,Lewis LJ,Aubin CE,Geitmann A

更新日期：2006-11-01 00:00:00

abstract：:The superficial femoral artery (SFA) is a typical atherosclerosis-prone site. We aimed to explore whether the tortuosity of the SFA associates with the occurrence of atherosclerosis and investigate how vascular tortuosity influences the characteristics of blood flow. Ten patients diagnosed with atherosclerotic disease...

journal_title：Biomechanics and modeling in mechanobiology

authors： Li X,Liu X,Li X,Xu L,Chen X,Liang F

更新日期：2019-08-01 00:00:00

abstract：:Inferior vena cava (IVC) filters are medical devices designed to provide a mechanical barrier to the passage of emboli from the deep veins of the legs to the heart and lungs. Despite decades of development and clinical use, IVC filters still fail to prevent the passage of all hazardous emboli. The objective of this st...

journal_title：Biomechanics and modeling in mechanobiology

authors： Aycock KI,Campbell RL,Manning KB,Craven BA

更新日期：2017-06-01 00:00:00

abstract：:This study evaluated the ability of different in vitro mechanical loading tests to promote new mineral formation at bonded dentin interfaces. This research demonstrated a sequential transition in the dentin remineralizing procedure through the analysis of the mineral and matrix gradients. Mechanical loading in phospho...

journal_title：Biomechanics and modeling in mechanobiology

authors： Toledano M,Aguilera FS,Cabello I,Osorio R

更新日期：2014-11-01 00:00:00

abstract：:Tissue expansion is a common surgical procedure to grow extra skin through controlled mechanical over-stretch. It creates skin that matches the color, texture, and thickness of the surrounding tissue, while minimizing scars and risk of rejection. Despite intense research in tissue expansion and skin growth, there is a...

journal_title：Biomechanics and modeling in mechanobiology

authors： Zöllner AM,Buganza Tepole A,Gosain AK,Kuhl E

更新日期：2012-07-01 00:00:00

abstract：:Experimental evidence suggests that interstitial fluid flow is a stimulus for mechanoadaptation in bone. Bone adaptation is sensitive to the frequency of loading and rest insertion between load cycles. We investigated the effects of permeability, frequency and rest insertion on fluid flow in bone using finite-element ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Pereira AF,Shefelbine SJ

更新日期：2014-01-01 00:00:00

abstract：:The present study addresses the effect of muscle activation contributions to mitral valve leaflet response during systole. State-of-art passive hyperelastic material modeling is employed in combination with a simple active stress part. Fiber families are assumed in the leaflets: one defined by the collagen and one def...

journal_title：Biomechanics and modeling in mechanobiology

authors： Skallerud B,Prot V,Nordrum IS

更新日期：2011-02-01 00:00:00

abstract：:Detailed knowledge about the mechanical properties of brain can improve numerical modeling of the brain under various loading conditions. The success of this modeling depends on constitutive model and reliable extraction of its material constants. The isotropy of the brain tissue is a key factor which affects the form...

journal_title：Biomechanics and modeling in mechanobiology

authors： Felfelian AM,Baradaran Najar A,Jafari Nedoushan R,Salehi H

更新日期：2019-12-01 00:00:00

abstract：:Large scale changes to lipid bilayer shapes are well represented by the Helfrich model. However, there are membrane processes that take place at smaller length scales that this model cannot address. In this work, we present a one-dimensional continuum model that captures the mechanics of the lipid bilayer membrane at ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Rangamani P,Benjamini A,Agrawal A,Smit B,Steigmann DJ,Oster G

更新日期：2014-08-01 00:00:00

abstract：:There is a growing interest in the development of patient-specific finite element models of the human lumbar spine for both the assessment of injury risk and the development of treatment strategies. A current challenge in implementing these models is that the outer annulus fibrosus of the disc is composed of concentri...

journal_title：Biomechanics and modeling in mechanobiology

authors： Michalek AJ

更新日期：2019-10-01 00:00:00

abstract：:This paper evaluates numerically coupled blood flow and wall structure interactions in a representative stented abdominal aortic aneurysm (AAA) model, leading potentially to endovascular graft (EVG) failure. A total of 12 biomechanical contributors to possible EVG migration were considered. The results show that after...

journal_title：Biomechanics and modeling in mechanobiology

authors： Li Z,Kleinstreuer C,Farber M

更新日期：2005-12-01 00:00:00

abstract：:The mechanical behavior of most biological soft tissue is nonlinear viscoelastic rather than elastic. Many of the models previously proposed for soft tissue involve ad hoc systems of springs and dashpots or require measurement of time-dependent constitutive coefficient functions. The model proposed here is a system of...

journal_title：Biomechanics and modeling in mechanobiology

authors： Haslach HW Jr

更新日期：2005-03-01 00:00:00

abstract：:The monitoring of the ciliated walls in the uterine tube has supreme importance in enhancing the sperm to reach the egg (capacitation processes), and at peristaltic ciliary flow has a more favorable residual time along the canal when compared to the peristaltic flow. Based on the importance of this study, a mathematic...

journal_title：Biomechanics and modeling in mechanobiology

authors： Zaher AZ,Moawad AMA,Mekheimer KS,Bhatti MM

更新日期：2021-01-03 00:00:00

abstract：:Lymph is transported along collecting lymphatic vessels by intrinsic and extrinsic pumping. The walls have muscle of a type intermediate between blood-vascular smooth muscle and myocardium; a contracting segment between two valves (a lymphangion) constitutes a pump. This intrinsic mechanism is investigated ex vivo in ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Bertram CD,Macaskill C,Davis MJ,Moore JE Jr

更新日期：2017-12-01 00:00:00

abstract：:Disease alters tissue microstructure, which in turn affects the macroscopic mechanical properties of tissue. In elasticity imaging, the macroscopic response is measured and is used to infer the spatial distribution of the elastic constitutive parameters. When an empirical constitutive model is used, these parameters c...

journal_title：Biomechanics and modeling in mechanobiology

authors： Liu T,Hall TJ,Barbone PE,Oberai AA

更新日期：2017-04-01 00:00:00

abstract：:The action induced by artificial sphincteric devices to provide urinary continence is related to the problem of evaluating the interaction between the occlusive cuff and the urethral duct. The intensity and distribution of the force induced within the region of application determine a different occlusion process and p...

journal_title：Biomechanics and modeling in mechanobiology

authors： Natali AN,Carniel EL,Fontanella CG,Todros S,De Benedictis GM,Cerruto MA,Artibani W

更新日期：2017-08-01 00:00:00

abstract：:The primary capillary plexus in early yolk sacs is remodeled into matured vitelline vessels aligned in the direction of blood flow at the onset of cardiac contraction. We hypothesized that the influence of fluid shear stress on cellular behaviors may be an underlying mechanism by which some existing capillary channels...

journal_title：Biomechanics and modeling in mechanobiology

authors： Blatnik JS,Schmid-Schönbein GW,Sung LA

更新日期：2005-12-01 00:00:00

abstract：:A growing volume of experimental evidence demonstrates that mechanical stress plays a significant role in growth, proliferation, apoptosis, gene expression, electrophysiological properties and many other aspects of neurons. In this review, first, the mechanical microenvironment and properties of neurons under in vivo ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Wang Y,Wang W,Li Z,Hao S,Wang B

更新日期：2016-10-01 00:00:00