Arterial pulse attenuation prediction using the decaying rate of a pressure wave in a viscoelastic material model.

abstract：:By following the common definition of forward-dynamics simulations, i.e. predicting movement based on (neural) muscle activity, this work describes, for the first time, a forward-dynamics simulation framework of a musculoskeletal system, in which all components are represented as continuous, three-dimensional, volumet...

journal_title：Biomechanics and modeling in mechanobiology

authors： Röhrle O,Sprenger M,Schmitt S

更新日期：2017-06-01 00:00:00

abstract：:This paper evaluates numerically coupled blood flow and wall structure interactions in a representative stented abdominal aortic aneurysm (AAA) model, leading potentially to endovascular graft (EVG) failure. A total of 12 biomechanical contributors to possible EVG migration were considered. The results show that after...

journal_title：Biomechanics and modeling in mechanobiology

authors： Li Z,Kleinstreuer C,Farber M

更新日期：2005-12-01 00:00:00

abstract：:Actin stress fibers (SFs), a contractile apparatus in nonmuscle cells, possess a contractile unit that is apparently similar to the sarcomere of myofibrils in muscles. The function of SFs has thus often been addressed based on well-characterized properties of muscles. However, unlike the fixed number of myosin molecul...

journal_title：Biomechanics and modeling in mechanobiology

authors： Saito T,Huang W,Matsui TS,Kuragano M,Takahashi M,Deguchi S

更新日期：2020-08-10 00:00:00

abstract：:Determining the biomechanical behavior of heart valve leaflet tissues in a noninvasive manner remains an important clinical goal. While advances in 3D imaging modalities have made in vivo valve geometric data available, optimal methods to exploit such information in order to obtain functional information remain to be ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Aggarwal A,Sacks MS

更新日期：2016-08-01 00:00:00

abstract：:Uniaxial tensile and relaxation tests were carried out on annulus fibrosus samples carved out in the circumferential direction. Images were shot perpendicularly to the loading direction. Digital image correlation techniques accurately measured the evolution of full displacement fields in both transverse directions: pl...

journal_title：Biomechanics and modeling in mechanobiology

authors： Baldit A,Ambard D,Cherblanc F,Royer P

更新日期：2014-06-01 00:00:00

abstract：:Long-term adaptation of soft tissues is realized through growth and remodeling (G&R). Mathematical models are powerful tools in testing hypotheses on G&R and supporting the design and interpretation of experiments. Most theoretical G&R studies concentrate on description of either growth or remodeling. Our model combin...

journal_title：Biomechanics and modeling in mechanobiology

authors： Machyshyn IM,Bovendeerd PH,van de Ven AA,Rongen PM,van de Vosse FN

更新日期：2010-12-01 00:00:00

abstract：:Bone fracture healing is a complex process in which angiogenesis or the development of a blood vessel network plays a crucial role. In this paper, a mathematical model is presented that simulates the biological aspects of fracture healing including the formation of individual blood vessels. The model consists of parti...

journal_title：Biomechanics and modeling in mechanobiology

authors： Peiffer V,Gerisch A,Vandepitte D,Van Oosterwyck H,Geris L

更新日期：2011-06-01 00:00:00

abstract：:The reopening of fluid-occluded pulmonary airways generates microbubble flows which impart complex hydrodynamic stresses to the epithelial cells lining airway walls. In this study we used boundary element solutions and finite element techniques to investigate how cell rheology influences the deformation and injury of ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Dailey HL,Ghadiali SN

更新日期：2010-06-01 00:00:00

abstract：:As a degenerative and inflammatory desease of elderly patients, about 80% of abdominal aortic aneurysms (AAA) show considerable wall calcification. Effect of calcifications on computational wall stress analyses of AAAs has been rarely treated in literature so far. Calcifications are heterogeneously distributed, non-fi...

journal_title：Biomechanics and modeling in mechanobiology

authors： Maier A,Gee MW,Reeps C,Eckstein HH,Wall WA

更新日期：2010-10-01 00:00:00

abstract：:Intracellular calcium dynamics plays an important role in the regulation of vascular endothelial cellular functions. In order to probe the intracellular calcium dynamic response under synergistic effect of wall shear stress (WSS) and adenosine triphosphate (ATP) signals, a novel microfluidic device, which provides the...

journal_title：Biomechanics and modeling in mechanobiology

authors： Chen ZZ,Yuan WM,Xiang C,Zeng DP,Liu B,Qin KR

更新日期：2019-02-01 00:00:00

abstract：:The basic aim of the present contribution is the qualitative simulation of healing phenomena typically encountered in hard and soft tissue mechanics. The mechanical framework is provided by the theory of open system thermodynamics, which will be formulated in the spatial as well as in the material motion context. Whil...

journal_title：Biomechanics and modeling in mechanobiology

authors： Kuhl E,Steinmann P

更新日期：2004-06-01 00:00:00

abstract：:Aortic valve (AV) calcification is a highly prevalent disease with serious impact on mortality and morbidity. The exact causes and mechanisms of AV calcification are unclear, although previous studies suggest that mechanical forces play a role. It has been clinically demonstrated that calcification preferentially occu...

journal_title：Biomechanics and modeling in mechanobiology

authors： Yap CH,Saikrishnan N,Yoganathan AP

更新日期：2012-01-01 00:00:00

abstract：:Experiments have demonstrated biological tissues grow by mechanically sensing their localized curvature, therefore making geometry a key consideration for tissue scaffold design. We developed a simulation approach for modeling tissue growth on beam-based geometries of repeating unit cells, with four lattice topologies...

journal_title：Biomechanics and modeling in mechanobiology

authors： Egan PF,Shea KA,Ferguson SJ

更新日期：2018-10-01 00:00:00

abstract：:Understanding the mechanical behavior of multicellular monolayers and spheroids is fundamental to tissue culture, organism development, and the early stages of tumor growth. Proliferating cells in monolayers and spheroids experience mechanical forces as they grow and divide and local inhomogeneities in the mechanical ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Lejeune E,Linder C

更新日期：2018-06-01 00:00:00

abstract：:The collagen fibril network is an important factor for the depth-dependent mechanical behaviour of adult articular cartilage (AC). Recent studies show that collagen orientation is parallel to the articular surface throughout the tissue depth in perinatal animals, and that the collagen orientations transform to a depth...

journal_title：Biomechanics and modeling in mechanobiology

authors： van Turnhout MC,Kranenbarg S,van Leeuwen JL

更新日期：2011-04-01 00:00:00

abstract：:Adherent cells normally apply forces as a generic means of sensing and responding to the mechanical nature of their surrounding environment. How these forces vary as a function of the extracellular rigidity is critical to understanding the regulatory functions that drive important phenomena such as wound healing or mu...

journal_title：Biomechanics and modeling in mechanobiology

authors： Borau C,Kamm RD,García-Aznar JM

更新日期：2014-04-01 00:00:00

abstract：:The immersed boundary method (IBM) has been frequently utilized to simulate the motion and deformation of biological cells and capsules in various flow situations. Despite the convenience in dealing with flow-membrane interaction, direct implementation of membrane viscosity in IBM suffers severe numerical instability....

journal_title：Biomechanics and modeling in mechanobiology

authors： Li P,Zhang J

更新日期：2020-12-01 00:00:00

abstract：:We use supersonic shear wave imaging (SSI) technique to measure not only the linear but also the nonlinear elastic properties of brain matter. Here, we tested six porcine brains ex vivo and measured the velocities of the plane shear waves induced by acoustic radiation force at different states of pre-deformation when ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Jiang Y,Li G,Qian LX,Liang S,Destrade M,Cao Y

更新日期：2015-10-01 00:00:00

abstract：:A three-dimensional finite-element fluid/structure interaction model of an intravascular lymphatic valve was constructed, and its properties were investigated under both favourable and adverse pressure differences, simulating valve opening and valve closure, respectively. The shear modulus of the neo-Hookean material ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Bertram CD

更新日期：2020-12-01 00:00:00

abstract：:Cell deformability and mechanical responses of living cells depend closely on the dynamic changes in the structural architecture of the cytoskeleton (CSK). To describe the dynamic reorganization and the heterogeneity of the prestressed multi-modular CSK, we developed a two-dimensional model for the CSK which was taken...

journal_title：Biomechanics and modeling in mechanobiology

authors： Milan JL,Wendling-Mansuy S,Jean M,Chabrand P

更新日期：2007-11-01 00:00:00

abstract：:A contact finite element (FE) formulation is introduced, amenable to patient-specific analysis of cumulative cartilage mechano-stimulus attributable to habitual functional activity. CT scans of individual human ankles are segmented to delineate bony margins. Each bone surface is projected outward to create a second su...

journal_title：Biomechanics and modeling in mechanobiology

authors： Anderson DD,Goldsworthy JK,Shivanna K,Grosland NM,Pedersen DR,Thomas TP,Tochigi Y,Marsh JL,Brown TD

更新日期：2006-06-01 00:00:00

abstract：:Congenital heart defects (CHDs) are abnormalities in the heart structure present at birth. One important condition is hypoplastic left heart syndrome (HLHS) where severely underdeveloped left ventricle (LV) cannot support systemic circulation. HLHS usually initiates as localized tissue malformations with no underlying...

journal_title：Biomechanics and modeling in mechanobiology

authors： Salman HE,Alser M,Shekhar A,Gould RA,Benslimane FM,Butcher JT,Yalcin HC

更新日期：2021-01-22 00:00:00

abstract：:Human embryonic stem cells (hESCs) can differentiate to three germ layers within biochemical and biomechanical niches. The complicated mechanical environments in vivo could have diverse effects on the fate decision and biological functions of hESCs. To globally screen mechanosensitive molecules, three typical types of...

journal_title：Biomechanics and modeling in mechanobiology

authors： Zhang F,Wang J,Lü D,Zheng L,Shangguan B,Gao Y,Wu Y,Long M

更新日期：2020-08-18 00:00:00

abstract：:An efficient solver for large-scale linear [Formula: see text] simulations was extended for nonlinear material behavior. The material model included damage-based tissue degradation and fracture. The new framework was applied to 20 trabecular biopsies with a mesh resolution of [Formula: see text]. Suitable material par...

journal_title：Biomechanics and modeling in mechanobiology

authors： Stipsitz M,Zysset PK,Pahr DH

更新日期：2020-06-01 00:00:00

abstract：:Thrombosis is a major concern in blood-coated medical devices. Contact activation, which is the initial part of the coagulation cascade in device-related thrombosis, is not considered in current thrombus formation models. In the present study, pro-coagulant reactions including the contact activation system are coupled...

journal_title：Biomechanics and modeling in mechanobiology

authors： Méndez Rojano R,Mendez S,Nicoud F

更新日期：2018-06-01 00:00:00

abstract：:A dynamic model is proposed for shear stress induced adenosine triphosphate (ATP) release from endothelial cells (ECs). The dynamic behavior of the ATP/ADP concentration at the endothelial surface by viscous shear flow is investigated through simulation studies based on the dynamic ATP release model. The numerical res...

journal_title：Biomechanics and modeling in mechanobiology

authors： Qin KR,Xiang C,Xu Z,Cao LL,Ge SS,Jiang ZL

更新日期：2008-10-01 00:00:00

abstract：:Conventional brain injury metrics are scalars that treat the whole head/brain as a single unit but do not characterize the distribution of brain responses. Here, we establish a network-based "response feature matrix" to characterize the magnitude and distribution of impact-induced brain strains. The network nodes and ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Wu S,Zhao W,Rowson B,Rowson S,Ji S

更新日期：2020-06-01 00:00:00

abstract：:A mechanics-based mathematical model of retinal detachment due to the geometric changes of the eye associated with the evolution of myopia is developed. This includes deformation of the retina due to biological growth of the retina, as well as elastic deformation imposed on the retina by the myopic change in shape of ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Lakawicz JM,Bottega WJ,Fine HF,Prenner JL

更新日期：2020-04-01 00:00:00

abstract：:Computational fluid dynamics (CFD) is an increasingly used method for investigation of hemodynamic parameters and their alterations under pathological conditions, which are important indicators for diagnosis of cardiovascular disease. In hemodynamic simulation models, the employment of appropriate boundary conditions ...

journal_title：Biomechanics and modeling in mechanobiology

authors： Xu P,Liu X,Zhang H,Ghista D,Zhang D,Shi C,Huang W

更新日期：2018-12-01 00:00:00

abstract：:Skin expansion delivers newly grown skin that maintains histological and mechanical features of the original tissue. Although it is the gold standard for cutaneous defect correction today, the underlying mechanisms remain poorly understood. Here we present a novel technique to quantify anisotropic prestrain, deformati...

journal_title：Biomechanics and modeling in mechanobiology

authors： Buganza Tepole A,Gart M,Purnell CA,Gosain AK,Kuhl E

更新日期：2015-10-01 00:00:00