The correlation between intestinal dysbiosis and the development of ankylosing spondylitis.

Abstract:

:The pathogenesis and development of ankylosing spondylitis (AS) is concealed and complicated. In recent years, alterations in gut microbiota of AS patients have been largely investigated, although the underlying mechanisms remain unclear. This article reviews the recent studies on changes of gut microbiota in AS patients, and discusses the possible correlation between intestinal dysbiosis and AS development from aspects including genetic factor HLA-B27, mucosal immune responses and the depression accompanying AS.

journal_name

Microb Pathog

journal_title

Microbial pathogenesis

authors

Zhang L,Hu Y,Xu Y,Li P,Ma H,Li X,Li M

doi

10.1016/j.micpath.2019.04.038

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

188-192

eissn

0882-4010

issn

1096-1208

pii

S0882-4010(18)31598-5

journal_volume

132

pub_type

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