Characterization of LIC11207, a novel leptospiral protein that is recognized by human convalescent sera and prevents apoptosis of polymorphonuclear leukocytes.

abstract：:Mycobacterial antigens were detected in a cell surface ELISA on murine dissociated Schwann cells infected with Mycobacterium leprae. The time kinetics of expression and its refractoriness to modulation with monensin suggests that the antigens are likely to be integrated into the membrane during bacterial entry. This m...

journal_title：Microbial pathogenesis

authors： Birdi TJ,D'Souza S,Antia NH

更新日期：1997-03-01 00:00:00

abstract：:Aeromonas are ubiquitous in aquatic habitats. However some species can cause infections in humans, but rarely meningitis. Here we describe the isolation and characterization of an Aeromonas strain from cerebrospinal fluid of a meningitis patient. The isolate, identified as A. trota by biochemical and molecular methods...

journal_title：Microbial pathogenesis

authors： Dallagassa CB,Surek M,Vizzotto BS,Prediger KC,Moriel B,Wolf S,Weiss V,Cruz LM,Assis FEA,Paludo KS,Rego FGM,Farah SMSS,Picheth G,Souza EM,Pedrosa FO,Chubatsu LS,Fadel-Picheth CMT

更新日期：2018-03-01 00:00:00

abstract：:Hemolysins are cytolytic proteins which have been extensively characterized at the molecular level, however, their in vivo functions remain unclear. This study analyzed the association of hemolysin production with the inflammatory response in patients with urinary tract infection (UTI). Infants and children with their...

journal_title：Microbial pathogenesis

authors： Connell H,de Man P,Jodal U,Lincoln K,Svanborg C

更新日期：1993-06-01 00:00:00

abstract：:Acinetobacter nosocomialis is an important nosocomial pathogen that causes a variety of opportunistic infections; however, pathogenesis of this microorganism has not yet been characterized. The aim of this study was to investigate the secretion of outer membrane vesicles (OMVs) from A. nosocomialis and to determine th...

journal_title：Microbial pathogenesis

authors： Nho JS,Jun SH,Oh MH,Park TI,Choi CW,Kim SI,Choi CH,Lee JC

更新日期：2015-04-01 00:00:00

abstract：:We analyzed here the complete genome sequences of a highly virulent Flavobacterium columnare Pf1 strain isolated in our laboratory. The complete genome consists of a 3,171,081 bp circular DNA with 2784 predicted protein-coding genes. Among these, 286 genes were predicted as antibiotic resistance genes, including 32 RN...

journal_title：Microbial pathogenesis

authors： Zhang Y,Zhao L,Chen W,Huang Y,Yang L,Sarathbabu V,Wu Z,Li J,Nie P,Lin L

更新日期：2017-10-01 00:00:00

abstract：:Fast emerging antibiotic resistance in pathogens requires special attention for strengthening the reservoir of antimicrobial compounds. In view of this, several peptides with known antimicrobial activities have been reported to enhance the efficacy of antibiotics against multidrug resistant (MDR) pathogens. In the pre...

journal_title：Microbial pathogenesis

authors： Rishi P,Vij S,Maurya IK,Kaur UJ,Bharati S,Tewari R

更新日期：2018-11-01 00:00:00

abstract：:Klebsiella pneumoniae (K. pneumoniae) is one of the major pathogen associated with nosocomial infections, especially catheter associated urinary tract infections which involved biofilm formation. This study was designed to evaluate the antibiofilm efficacy of gold nanoparticle conjugated with chlorhexidine (Au-CHX) ag...

journal_title：Microbial pathogenesis

authors： Ahmed A,Khan AK,Anwar A,Ali SA,Shah MR

更新日期：2016-09-01 00:00:00

abstract：:The objective of this paper was to evaluate NTPDase and 5'-nucleotidase activities in platelets of bovine with and without spleen and infected by Anaplasma marginale. Our results demonstrate that infection along with splenectomy is able of inducing a profile of cellular protection, which showed an increase in the degr...

journal_title：Microbial pathogenesis

authors： Doyle RL,Oliveira CB,França RT,Doleski PH,Souza VC,Leal DBR,Martins JR,Lopes STA,Machado G,Da Silva AS,Andrade CM

更新日期：2016-06-01 00:00:00

abstract：:The initiation of many infectious diseases involves specific adhesion of bacteria to host tissue proteins and carbohydrates. Staphylococcus aureus is known to bind specifically to several proteins in the extracellular matrix (ECM). We report the quantification of the collagen and fibronectin adhesin densities on the s...

journal_title：Microbial pathogenesis

authors： Mohamed N,Visai L,Speziale P,Ross JM

更新日期：2000-12-01 00:00:00

abstract：:The corticosteroid-treated animal is well established as an experimental model for the study of Pneumocystis carinii pneumonitis (PCP). Latent or acquired infection with P. carinii in the murine lung progresses to fatal pneumonitis when the host is profoundly immunocompromized. In this study the effects of five immuno...

journal_title：Microbial pathogenesis

authors： Oz HS,Hughes WT,Rehg JE,Thomas EK

更新日期：2000-09-01 00:00:00

abstract：:Genital serovariants of Chlamydia trachomatis establish infection by attachment, entry and multiplication within human endometrial epithelial cells. In previous studies, a chlamydial recombinant Escherichia coli was identified which exhibited a specific adherent phenotype to endometrial epithelial cells closely resemb...

journal_title：Microbial pathogenesis

authors： Schmiel DH,Raulston JE,Fox E,Wyrick PB

更新日期：1995-10-01 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. ...

journal_title：Microbial pathogenesis

authors： Heng Y,Mao W,Yong M,Yang G,Su Q,Wang J

更新日期：2018-08-08 00:00:00

abstract：:Using whole bacteria, rather than extracted, purified DNA samples, we amplified the papE gene sequences from 63 Escherichia coli isolates belonging to O serogroups O1, O2 and O6. These isolates were from collections separated temporally as well as geographically: from four cities in the US and one in Sweden. PCR ampli...

journal_title：Microbial pathogenesis

authors： Jantausch BA,Hull SI

更新日期：1996-06-01 00:00:00

abstract：:Vibrio cholerae elaborates zonula occludens toxin (Zot), a protein that increases the permeability of small intestinal mucosa by opening intercellular tight junctions. The zot gene is located, together with the genes encoding CT and Ace enterotoxins, within the genome of V. cholerae filamentous phage CTXsmall ef, Cyri...

journal_title：Microbial pathogenesis

authors： Uzzau S,Cappuccinelli P,Fasano A

更新日期：1999-12-01 00:00:00

abstract：:Escherichia coli heat-stable enterotoxin Ip (STIp) is a typical extracellular toxin consisting of 18 amino acid residues synthesized as a precursor of pre (amino acid residues 1 to 19), pro (amino acid residues 20 to 54), and mature (amino acid residues 55 to 72) regions. STIp synthesized in the cytoplasm must cross t...

journal_title：Microbial pathogenesis

authors： Yamanaka H,Nomura T,Fujii Y,Okamoto K

更新日期：1998-09-01 00:00:00

abstract：:Most strains of Salmonella enterica subspecies enterica serotype typhimurium (S. typhimurium) naturally harbour a virulence plasmid which carries the salmonella plasmid virulence (spv) genes. However, isolates belonging to certain phage types are generally found without the plasmid. We have utilized a self-transferabl...

journal_title：Microbial pathogenesis

authors： Olsen JE,Brown DJ,Thomsen LE,Platt DJ,Chadfield MS

更新日期：2004-06-01 00:00:00

abstract：:Neisseria meningitidis, but not Haemophilus influenzae, damage cultured human endothelial cells. We have undertaken a study to generate genetically and structurally defined lipopolysaccharide (LPS) mutant strains of meningococci for functional studies to assess the role of surface exposed oligosaccharides in imparting...

journal_title：Microbial pathogenesis

authors： Jennings MP,Bisercic M,Dunn KL,Virji M,Martin A,Wilks KE,Richards JC,Moxon ER

更新日期：1995-12-01 00:00:00

abstract：:A novel N-acyl substituted indole-linked benzimidazoles and naphthoimidazoles were synthesized. Their chemical structures were confirmed using spectroscopic tools including 1H NMR, 13C NMR and CHN-elemental analyses. Anti inflammatory activity for all target compounds was evaluated in-vitro. The synthesized compounds ...

journal_title：Microbial pathogenesis

authors： Abraham R,Prakash P,Mahendran K,Ramanathan M

更新日期：2018-01-01 00:00:00

abstract：:Interleukin-8 (IL-8) is a neutrophil and T-lymphocyte chemotactic and activating factor. This cytokine is produced by many cell types including macrophages in response to a variety of microbial and non-microbial agents. In the present study, we determined the nucleotide sequence for bovine IL-8 cDNA. The amino acid se...

journal_title：Microbial pathogenesis

authors： Morsey MA,Popowych Y,Kowalski J,Gerlach G,Godson D,Campos M,Babiuk LA

更新日期：1996-04-01 00:00:00

abstract：:Brucellosis is a worldwide zoonotic infectious disease that has significant economic effects on animal production and human health. The host macrophage -Brucella interaction is critical to the establishment of infections. Thus, the kinetic transcriptional profile of gene expression in macrophages infected with the Bru...

journal_title：Microbial pathogenesis

authors： Liu Q,Han W,Sun C,Zhou L,Ma L,Lei L,Yan S,Liu S,Du C,Feng X

更新日期：2012-05-01 00:00:00

abstract：:Aeromonas hydrophila is one of the main causative agent of high mortality and significative economic losses in aquaculture and has become increasingly resistant to conventional antibiotics. One feasible alternative to control and treat it is the use of essential oils. This study aimed to evaluate A. hydrophila suscept...

journal_title：Microbial pathogenesis

authors： F Souza C,Baldissera MD,A Vaucher R,Lopes LQ,Vizzotto BS,Raffin RP,Santos RC,L da Veiga M,U M da Rocha MI,Stefani LM,Baldisserotto B

更新日期：2016-09-01 00:00:00

abstract：:Helicobacter pylori (H. pylori) usually colonizes the gastric mucosa of more than 50% of the human population, causing an infection that may appear in early childhood and can persist for life. H. pylori is suggested as the main cause of peptic ulcer and chronic gastritis. It is also associated with gastric cancer. Its...

journal_title：Microbial pathogenesis

authors： Bagheri N,Azadegan-Dehkordi F,Rafieian-Kopaei M,Rahimian G,Asadi-Samani M,Shirzad H

更新日期：2016-11-01 00:00:00

abstract：:We previously demonstrated that incubation of E. coli in normal human serum (NHS) resulted in the release of a finite fraction (approximately 30%) of LPS from the bacterial outer membrane. In experiments reported here, we examined factors which may enhance or diminish the capacity of NHS to mediate this limited LPS re...

journal_title：Microbial pathogenesis

authors： Tesh VL,Morrison DC

更新日期：1988-03-01 00:00:00

abstract：:Mycobacterium tuberculosis (Mtb) has coevolved with a human host to evade and exploit the immune system in multiple ways. Mtb is an enormously successful human pathogen that can remain undetected in hosts for decades without causing clinical disease. While tuberculosis (TB) represents a perfect prototype of host-patho...

journal_title：Microbial pathogenesis

authors： Baindara P

更新日期：2019-05-01 00:00:00

abstract：:Toxoplasma gondii is an intracellular obligate parasitic protozoon that can infect all warm-blooded animals, causing zoonotic toxoplasmosis. So far, there is no commercial toxoplasmosis vaccine for human use. In the present study, we constructed a DNA vaccine cocktail which includes the surface protein (SAG1) and the ...

journal_title：Microbial pathogenesis

authors： Sun H,Li J,Xiao T,Huang XD,Wang LJ,Huang BC,Yin K,Liu GZ,Xu C,Wei QK

更新日期：2020-10-01 00:00:00

abstract：:According to the WHO factsheet, although approximately half a million brucellosis cases are reported annually, the true incidence is always 10-25 times higher than the reported number of cases. Therefore, we face a common yet uncommonly recognized entity of brucellosis, which highlights the importance of providing pre...

journal_title：Microbial pathogenesis

authors： Avijgan M,Rostamnezhad M,Jahanbani-Ardakani H

更新日期：2019-04-01 00:00:00

abstract：:High-affinity binding sites for P-fimbriated and for 075X-positive Escherichia coli were located in the human kidney. Frozen sections of normal human kidney were double-stained first with fluorochrome-labelled bacteria and then with fluorochrome-labelled nephron site-specific lectins or antibodies. The P-fimbriate rec...

journal_title：Microbial pathogenesis

authors： Nowicki B,Holthöfer H,Saraneva T,Rhen M,Väisänen-Rhen V,Korhonen TK

更新日期：1986-04-01 00:00:00

abstract：:An mdaB mutant strain in a quinone reductase (MdaB) of Helicobacter hepaticus type strain ATCC51449 was constructed by insertional mutagenesis, and the MdaB protein was purified and compared to the Helicobacter pylori enzyme. While wild type H. hepaticus cells could tolerate 6% O(2) for growth, the mdaB strain was cle...

journal_title：Microbial pathogenesis

authors： Hong Y,Wang G,Maier RJ

更新日期：2008-02-01 00:00:00

abstract：:We obtained biologically active purified leukotoxin (Lkt) from Pasteurella haemolytica serotypel, strain 12296 using preparative sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). Three species of Lkt of molecular masses 95, 100, and 104 kDa were obtained. Purity of all three species of Lkt was conf...

journal_title：Microbial pathogenesis

authors： Yoo HS,Rajagopal BS,Maheswaran SK,Ames TR

更新日期：1995-04-01 00:00:00

abstract：:C1q, as a LAIR-1 ligand, maintains monocytes quiescence and possess immunosuppressive properties. To understand the roles and molecular mechanisms, C1q mediated inflammation cytokines and several pivotal proteins in THP-1 cells after H. pylori infection were detected. The results showed that the expression of IL-8, IL...

journal_title：Microbial pathogenesis

authors： Zhang Y,Li J,Rong Q,Xu Z,Ding Y,Cao Q,Ji X,Zhao H,Wu Y,Li B

更新日期：2019-06-01 00:00:00