Rs2015 Polymorphism in miRNA Target Site of Sirtuin2 Gene Is Associated with the Risk of Parkinson's Disease in Chinese Han Population.

abstract：:Pancreatic ductal adenocarcinoma (PDA) is the fourth most common cancer causing death in the United States. Early tumor recurrence is an important contributor to the dismal prognosis. The availability of an accurate prognostic biomarker for predicting disease recurrence following curative resection will be beneficial ...

journal_title：BioMed research international

authors： Osayi SN,Bloomston M,Schmidt CM,Ellison EC,Muscarella P

更新日期：2014-01-01 00:00:00

abstract：:Several factors, including compressive load and knee kinematics, have been shown to influence wear. External knee moments (a surrogate for load) have recently been correlated with the medial and lateral wear scar areas of an unconstrained, PCL retaining knee design. Therefore, the purpose of this study was to determin...

journal_title：BioMed research international

authors： Ngai V,Wimmer MA

更新日期：2015-01-01 00:00:00

abstract：:The polyherbal formulation containing Allium sativum L., Terminalia bellirica (Gaertn.) Roxb., Curcuma aeruginosa Roxb., and Amomum compactum Sol ex. Maton has been used for hypertension treatment empirically. Our previous study showed its blood pressure-lowering effect on a rat model of hypertension. However, toxicit...

journal_title：BioMed research international

authors： Sholikhah EN,Mustofa M,Nugrahaningsih DAA,Yuliani FS,Purwono S,Sugiyono S,Widyarini S,Ngatidjan N,Jumina J,Santosa D,Koketsu M

更新日期：2020-03-24 00:00:00

abstract：:Adverse obstetric outcomes, such as preeclampsia, preterm birth, gestational diabetes, and fetal growth restriction, are poorly predicted by maternal history and risk factors alone, especially in nulliparae. The ability to predict these outcomes from the first trimester would allow for the early initiation of prophyla...

journal_title：BioMed research international

authors： Kane SC,Costa Fda S,Brennecke S

更新日期：2014-01-01 00:00:00

abstract：:The proper functioning of a hospital computer system is an arduous work for managers and staff. However, inconsistent policies are frequent and can produce enormous problems, such as stolen information, frequent failures, and loss of the entire or part of the hospital data. This paper presents a new method named EMRlo...

journal_title：BioMed research international

authors： Martínez Monterrubio SM,Frausto Solis J,Monroy Borja R

更新日期：2015-01-01 00:00:00

abstract：:Prior to the "onset of hearing," developing cochlear inner hair cells (IHCs) and primary auditory neurons undergo experience-independent activity, which is thought to be important in retaining and refining neural connections in the absence of sound. One of the major hypotheses regarding the origin of such activity inv...

journal_title：BioMed research international

authors： Dayaratne MW,Vlajkovic SM,Lipski J,Thorne PR

更新日期：2014-01-01 00:00:00

abstract：:India is highly endemic to malaria with prevalence of all five species of human malaria parasites of Plasmodium genus. India is set for malaria elimination by 2030. Since cases of mixed Plasmodium species infections remain usually undetected but cause huge disease burden, in order to understand the distributional prev...

journal_title：BioMed research international

authors： Singh US,Siwal N,Pande V,Das A

更新日期：2017-01-01 00:00:00

abstract：:The aim of the study was to comparatively evaluate the fracture strength and mode of root canal treated teeth restored with resin composites with and without posts. The lingual cusps of root canal treated first upper premolars (n = 10/group) were removed down to cervical enamel and restored with the following: group A...

journal_title：BioMed research international

authors： Gaintantzopoulou MD,Farmakis ET,Eliades GC

更新日期：2018-08-14 00:00:00

abstract：INTRODUCTION:Tuberculosis is still one of the most important health problems in developing countries and increasing drug resistance is the main concern for its treatment. This study was designed to characterize the drug resistant Mycobacterium tuberculosis isolated from patients suffering from pulmonary tuberculosis in...

journal_title：BioMed research international

authors： Tavanaee Sani A,Shakiba A,Salehi M,Bahrami Taghanaki HR,Ayati Fard SF,Ghazvini K

更新日期：2015-01-01 00:00:00

abstract：:Bioadhesive nasal dosage forms are an attractive method for overcoming rapid mucociliary clearance transport in the nose and for delivering the drug directly to brain. The present study was designed to formulate chondroitin sulphate (CS) and chitosan (CH) nasal inserts employing zolmitriptan, an antimigraine drug. The...

journal_title：BioMed research international

authors： Kaur K,Kaur G

更新日期：2013-01-01 00:00:00

abstract：:Autophagy is involved in the development of numerous illnesses, including ischemia/reperfusion (I/R). Endothelial nitric oxide synthase (eNOS) participates in the protective effects of ischemic postconditioning (IPostC). However, it remains unclear whether eNOS-mediated autophagy serves as a critical role in IPostC in...

journal_title：BioMed research international

authors： Shao J,Miao C,Geng Z,Gu M,Wu Y,Li Q

更新日期：2019-02-10 00:00:00

abstract：:The availability of fluorescent dyes and the advances in the optical systems for in vivo imaging have stimulated an increasing interest in developing new methodologies to study and quantify the biodistribution of labeled agents. However, despite these great achievements, we are facing significant challenges in determi...

journal_title：BioMed research international

authors： Munisso MC,Yamaoka T

更新日期：2014-01-01 00:00:00

abstract：:Gold nanorods (GNRs) are considered one of the most promising forms of nanoparticles for nanobiotechnology; however, the problem of their toxicity is currently not resolved. We synthesised GNRs, modified with linear polyethyleneimine (PEI-GNRs), and examined their physicochemical and some biological properties in comp...

journal_title：BioMed research international

authors： Pyshnaya IA,Razum KV,Poletaeva JE,Pyshnyi DV,Zenkova MA,Ryabchikova EI

更新日期：2014-01-01 00:00:00

abstract：:With the development of nanotechnology, nanocarriers have been increasingly used for curative drug/gene delivery. Various nanocarriers are being introduced and assessed, such as polymer nanoparticles, liposomes, and micelles. As a novel theranostic system, nanocarriers hold great promise for ultrasound molecular imagi...

journal_title：BioMed research international

authors： Zhou QL,Chen ZY,Wang YX,Yang F,Lin Y,Liao YY

更新日期：2014-01-01 00:00:00

abstract：:This study attempted to find novel age-related macular degeneration (AMD) related genes based on 36 known AMD genes. The well-known shortest path algorithm, Dijkstra's algorithm, was applied to find the shortest path connecting each pair of known AMD related genes in protein-protein interaction (PPI) network. The gene...

journal_title：BioMed research international

authors： Zhang J,Jiang M,Yuan F,Feng KY,Cai YD,Xu X,Chen L

更新日期：2013-01-01 00:00:00

abstract：:This study was undertaken to evaluate the effect of 3D printed polycaprolactone (PCL)/β-tricalcium phosphate (β-TCP) scaffold containing bone demineralized and decellularized extracellular matrix (bdECM) and human recombinant bone morphogenetic protein-2 (rhBMP-2) on bone regeneration. Scaffolds were divided into PCL/...

journal_title：BioMed research international

authors： Bae EB,Park KH,Shim JH,Chung HY,Choi JW,Lee JJ,Kim CH,Jeon HJ,Kang SS,Huh JB

更新日期：2018-02-27 00:00:00

abstract：Objectives:To evaluate the role of short-term low-dose glucocorticoids in mild COVID-19 patients. Methods:We conducted a retrospective, cross-sectional, single-center study in Kunming, China. A total of 33 mild COVID-19 cases were divided into two treatment groups (with and without glucocorticoids, methylprednisolone,...

journal_title：BioMed research international

authors： Fu HY,Luo Y,Gao JP,Wang L,Li HJ,Li X,Xue L,Tang XQ,Li HW,Du YR

更新日期：2020-09-23 00:00:00

abstract：:Although triacylglycerol, the major component for lipid storage, is essential for normal physiology, its excessive accumulation causes obesity in adipose tissue and is associated with organ dysfunction in nonadipose tissue. Here, we focused on the Drosophila model to develop therapeutics for preventing obesity. The br...

journal_title：BioMed research international

authors： Men TT,Thanh DN,Yamaguchi M,Suzuki T,Hattori G,Arii M,Huy NT,Kamei K

更新日期：2016-01-01 00:00:00

abstract：:Diabetic foot ulcers (DFUs) are characterized by an unsatisfactory inflammatory and migratory response. Skin inflammation involves the participation of many cells and particularly macrophages. Macrophage function can be modulated by neuropeptides; however, little is known regarding the role of neurotensin (NT) as a mo...

journal_title：BioMed research international

authors： Moura LI,Silva L,Leal EC,Tellechea A,Cruz MT,Carvalho E

更新日期：2013-01-01 00:00:00

abstract：:Ambient assisted living (AAL) aims to help older persons "age-in-place" and manage everyday activities using intelligent and pervasive computing technology. AAL research, however, has yet to explore how AAL might support or collaborate with informal care partners (ICPs), such as relatives and friends, who play importa...

journal_title：BioMed research international

authors： Hwang AS,Truong KN,Cameron JI,Lindqvist E,Nygård L,Mihailidis A

更新日期：2015-01-01 00:00:00

abstract：:J-proteins are molecular chaperones and present in a wide variety of organisms from prokaryote to eukaryote. Based on their domain organizations, J-proteins can be classified into 4 types, that is, Type I, Type II, Type III, and Type IV. Different types of J-proteins play distinct roles in influencing cancer propertie...

journal_title：BioMed research international

authors： Feng P,Lin H,Chen W,Zuo Y

更新日期：2014-01-01 00:00:00

abstract：:It is well known that Down syndrome (DS) is a condition in which extra genetic material causes delays in the way a child develops, both mentally and physically. Intellectual disability is the foremost and most debilitating trait, which caused loss of cognitive abilities and the development of early onset Alzheimer's d...

journal_title：BioMed research international

authors： Yu B,Zhang B,Zhou WB,Wang QW,Yuan P,Yang YQ,Kong J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Although binge drinking prevalence and correlates among young people have been extensively studied in the USA and Northern Europe, less is known for Southern Europe countries with relatively healthier drinking cultures. OBJECTIVE:We aimed at analyzing prevalence and correlates of binge drinking in a represe...

journal_title：BioMed research international

authors： Bartoli F,Carretta D,Crocamo C,Schivalocchi A,Brambilla G,Clerici M,Carrà G

更新日期：2014-01-01 00:00:00

abstract：:In a bioprospecting effort towards novel thermostable lipases, we assessed the lipolytic profile of 101 bacterial strains isolated from the volcanic area of Santorini, Aegean Sea, Greece. Screening of lipase activity was performed both in agar plates and liquid cultures using olive oil as carbon source. Significant di...

journal_title：BioMed research international

authors： Stathopoulou PM,Savvides AL,Karagouni AD,Hatzinikolaou DG

更新日期：2013-01-01 00:00:00

abstract：Background:Fingertips are a common site for hand injuries. The ideal substitute for fingertip pulp is tissue that matches texturally with minimal donor site morbidity. We described anatomical findings from cadaveric studies and the reliability of the palmar ulnar artery perforator (PUAP) free flap techniques for the re...

journal_title：BioMed research international

authors： Pak CS,Jeon JI,Myung Y,Lee YK,Kim BJ,Jeong JH,Kim BK

更新日期：2018-05-09 00:00:00

abstract：:Retinal vein occlusion (RVO) is a common vascular disease of retina; however, the pathomechanism leading to RVO is not yet clear. In general, increasing age, hypertension, arteriosclerosis, diabetes mellitus, dyslipidemia, cardiovascular disorder, and cerebral stroke are systemic risk factors of RVO. However, RVO ofte...

journal_title：BioMed research international

authors： Kida T

更新日期：2017-01-01 00:00:00

abstract：:ACE inhibitory dipeptides from Xerocomus badius fermented shrimp processing waste were isolated with ethanol, macroporous resin, chloroform, and Sephadex G-10 in sequence and identified by LC-MS/MS system coupled with electrospray ionization source. Molecular docking was performed for exploring the mechanism of their ...

journal_title：BioMed research international

authors： Gao X,Li X,Yan P,Sun R,Kan G,Zhou Y

更新日期：2018-05-08 00:00:00

abstract：Objective:The objective was to study the risk and protective factors involved in retinal vascular development of preterm infants with retinopathy of prematurity. Methods:Between 2000 and 2017, 185 preterm infants were included in the protocol for retinopathy of prematurity. Risk factors associated with speed of retina...

journal_title：BioMed research international

authors： Solans Pérez de Larraya AM,Ortega Molina JM,Uberos Fernández J,González Ramírez AR,García Serrano JL

更新日期：2019-04-24 00:00:00

abstract：AIMS:Nausea and vomiting of pregnancy is the most common medical condition in pregnancy. There is an increasing trend to prescribe ondansetron although its safety for use in pregnancy has not been established. METHODS:Exposed pregnancies were all births in Western Australia, 2002-2005, where the mother was dispensed o...

journal_title：BioMed research international

authors： Colvin L,Gill AW,Slack-Smith L,Stanley FJ,Bower C

更新日期：2013-01-01 00:00:00

abstract：:Cancer cells acquire unique secretome compositions that contribute to tumor development and metastasis. The aim of our study was to elucidate the biological processes involved in cervical cancer, by performing a proteomic analysis of the secretome from the following informative cervical cell lines: SiHa (HPV16+), HeLa...

journal_title：BioMed research international

authors： Kontostathi G,Zoidakis J,Makridakis M,Lygirou V,Mermelekas G,Papadopoulos T,Vougas K,Vlamis-Gardikas A,Drakakis P,Loutradis D,Vlahou A,Anagnou NP,Pappa KI

更新日期：2017-01-01 00:00:00