The relationship between blood lead, blood pressure, stroke, and heart attacks in middle-aged British men.

abstract：BACKGROUND:Adverse cardiorespiratory health is associated with exposure to ambient particulate matter (PM). The highest PM concentrations in London occur in proximity to waste transfer stations (WTS), sites that experience high numbers of dust-laden, heavy-duty diesel vehicles transporting industrial and household wast...

journal_title：Environmental health perspectives

authors： Godri KJ,Duggan ST,Fuller GW,Baker T,Green D,Kelly FJ,Mudway IS

更新日期：2010-04-01 00:00:00

abstract：:The presence of blue-green algae (BGA) toxins in surface waters used for drinking water sources and recreation is receiving increasing attention around the world as a public health concern. However, potential risks from exposure to these toxins in contaminated health food products that contain BGA have been largely ig...

journal_title：Environmental health perspectives

authors： Gilroy DJ,Kauffman KW,Hall RA,Huang X,Chu FS

更新日期：2000-05-01 00:00:00

abstract：:Although chemical exposure has been associated with reduced reproduction in certain North American fish, reptiles, and mammals, definitive cause-and-effect data are lacking in many instances. Because the increasing use and global transport of industrial chemicals pose significant risk to successful reproduction, metho...

journal_title：Environmental health perspectives

authors： Hose JE,Guillette LJ

更新日期：1995-05-01 00:00:00

abstract：:The disruption of the reproductive system of male and female animals in the wild has been attributed to environmental chemicals (xenobiotics). The effects seen mirror alterations one might anticipate if the steroid hormone-dependent processes that regulate these systems were impaired. To determine whether xenobiotics ...

journal_title：Environmental health perspectives

authors： Danzo BJ

更新日期：1997-03-01 00:00:00

abstract：:The anatomy of the intestine is outlined. The kinetics of cell proliferation, differentiation, and migration in intestinal epithelium are described. The distribution of cell types between the proliferation and differentiation compartments of the epithelium is summarized. Seven preparations of intestine in current use ...

journal_title：Environmental health perspectives

authors： Porteous JW

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Traffic noise affects a large number of people, particularly in urbanized areas. Noise causes stress and annoyance, but less is known about the relationship between noise and depression. OBJECTIVE:We investigated the association of residential road traffic noise with depressive symptoms using 5-year follow-...

journal_title：Environmental health perspectives

authors： Orban E,McDonald K,Sutcliffe R,Hoffmann B,Fuks KB,Dragano N,Viehmann A,Erbel R,Jöckel KH,Pundt N,Moebus S

更新日期：2016-05-01 00:00:00

abstract：:Lead is a male reproductive toxicant. Data suggest that rats dosed with relatively high levels of lead acetate for short periods of time induced changes in the hypothalamic gonadotropin-releasing hormone (GnRH) at the molecular level, but these changes were attenuated with increased concentration of exposure. The curr...

journal_title：Environmental health perspectives

authors： Sokol RZ,Wang S,Wan YJ,Stanczyk FZ,Gentzschein E,Chapin RE

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Exposure to air pollution has been associated with higher C-reactive protein (CRP) levels, suggesting an inflammatory response. Not much is known about this association in pregnancy. OBJECTIVES:We investigated the associations of air pollution exposure during pregnancy with maternal and fetal CRP levels in ...

journal_title：Environmental health perspectives

authors： van den Hooven EH,de Kluizenaar Y,Pierik FH,Hofman A,van Ratingen SW,Zandveld PY,Lindemans J,Russcher H,Steegers EA,Miedema HM,Jaddoe VW

更新日期：2012-05-01 00:00:00

abstract：:In recent years, exposure of man to increasing amounts of metals has occurred rather generally from industrial contamination and variably from intake of dietary mineral supplements. Adverse effects of individual metals can be markedly altered by dietary levels of other essential and nonessential inorganic elements, es...

journal_title：Environmental health perspectives

authors： Fox MR

更新日期：1978-08-01 00:00:00

abstract：OBJECTIVE:This study was designed to determine whether prenatal mercury exposure, including potential releases from the World Trade Center (WTC) disaster, adversely affects fetal growth and child development. METHODS:We determined maternal and umbilical cord blood total mercury of nonsmoking women who delivered at ter...

journal_title：Environmental health perspectives

authors： Lederman SA,Jones RL,Caldwell KL,Rauh V,Sheets SE,Tang D,Viswanathan S,Becker M,Stein JL,Wang RY,Perera FP

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Exposure to certain phenols is ubiquitous because of their use in many consumer and personal care products. However, predictors of exposure have not been well characterized in most populations. OBJECTIVES:We sought to identify predictors of exposure and to assess the reproducibility of phenol concentrations...

journal_title：Environmental health perspectives

authors： Engel LS,Buckley JP,Yang G,Liao LM,Satagopan J,Calafat AM,Matthews CE,Cai Q,Ji BT,Cai H,Engel SM,Wolff MS,Rothman N,Zheng W,Xiang YB,Shu XO,Gao YT,Chow WH

更新日期：2014-07-01 00:00:00

abstract：:[35S]t-Butylbicyclophosphorothionate or [35S]TBPS is an improved radioligand for the picrotoxinin binding site in rat brain synaptic membranes. The toxic isomers of the hexachlorocyclohexanes, polychlorobornanes, and chlorinated cyclodienes displace [35S]TBPS with a stereospecificity and potency generally correlated w...

journal_title：Environmental health perspectives

authors： Casida JE,Lawrence LJ

更新日期：1985-09-01 00:00:00

abstract：:Male reproduction has been given little attention in science and in medical practice. However, a recent metaanalysis on semen quality, which clearly pointed to a decrease over the past 50 years, has been repeatedly quoted. Three recent reports have found that semen quality has declined among candidate semen donors dur...

journal_title：Environmental health perspectives

authors： Carlsen E,Giwercman A,Keiding N,Skakkebaek NE

更新日期：1995-10-01 00:00:00

abstract：:The nasal cavity is susceptible to chemically induced injury as a result of exposure to inhaled irritants. Some responses of the nasal mucosa to inhaled toxicants are species specific. These species-related differences in response may be due to variations in structural, physiologic, and biochemical factors, such as gr...

journal_title：Environmental health perspectives

authors： Harkema JR

更新日期：1990-04-01 00:00:00

abstract：:We present a model of the distribution of noise annoyance with the mean varying as a function of the noise exposure. Day-night level (DNL) and day-evening-night level (DENL) were used as noise descriptors. Because the entire annoyance distribution has been modeled, any annoyance measure that summarizes this distributi...

journal_title：Environmental health perspectives

authors： Miedema HM,Oudshoorn CG

更新日期：2001-04-01 00:00:00

abstract：:Epidemiologic studies report associations between particulate air pollution and cardiopulmonary morbidity and mortality. Although the underlying pathophysiologic mechanisms remain unclear, it has been hypothesized that altered autonomic function and pulmonary/systemic inflammation may play a role. In this study we exp...

journal_title：Environmental health perspectives

authors： Pope CA 3rd,Hansen ML,Long RW,Nielsen KR,Eatough NL,Wilson WE,Eatough DJ

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:We reviewed the scientific background for the current health-based World Health Organization (WHO) guideline value for manganese in drinking water. DATA SOURCES AND EXTRACTION:The initial starting point was the background document for the development of the WHO's guideline value for manganese in drinking wat...

journal_title：Environmental health perspectives

authors： Ljung K,Vahter M

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Toxicology studies have shown adverse effects of developmental exposure to industrial phenols. Evaluation in humans is challenged by potentially marked within-subject variability of phenol biomarkers in pregnant women, which is poorly characterized. OBJECTIVES:We aimed to characterize within-day, between-da...

journal_title：Environmental health perspectives

authors： Vernet C,Philippat C,Calafat AM,Ye X,Lyon-Caen S,Siroux V,Schisterman EF,Slama R

更新日期：2018-03-16 00:00:00

abstract：:Medically unexplained physical symptoms (MUPS) are persistent idiopathic symptoms that drive patients to seek medical care. MUPS syndromes include chronic fatigue syndrome, fibromyalgia syndrome, and multiple chemical sensitivities. When MUPS occur after an environmental exposure or injury, an adversarial social conte...

journal_title：Environmental health perspectives

authors： Engel CC Jr,Adkins JA,Cowan DN

更新日期：2002-08-01 00:00:00

abstract：:This study investigated the association between biomarkers of fetal exposure to cigarette smoke at the end of pregnancy, cotinine in cord serum and in maternal and newborn urine samples, and quantitative measurement of smoking intake and exposure evaluated by maternal self-reported questionnaire. Study subjects were 4...

journal_title：Environmental health perspectives

authors： Pichini S,Basagaña XB,Pacifici R,Garcia O,Puig C,Vall O,Harris J,Zuccaro P,Segura J,Sunyer J

更新日期：2000-11-01 00:00:00

abstract：:An important public health challenge has been the need to protect children's health. To accomplish this goal, the scientific community needs scientifically based child-specific risk assessment methods. Critical to their development is the need to understand mechanisms underlying children's sensitivity to environmental...

journal_title：Environmental health perspectives

authors： Faustman EM,Silbernagel SM,Fenske RA,Burbacher TM,Ponce RA

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Functional limitations are a major cause for needing care and institutionalization among older adults. Exposure to air pollution has been suggested to be associated with increased functional limitations in older people. OBJECTIVE:Our objective was to assess the association between air pollution and physical...

journal_title：Environmental health perspectives

authors： de Zwart F,Brunekreef B,Timmermans E,Deeg D,Gehring U

更新日期：2018-01-19 00:00:00

abstract：:Lung counting is highly geometry dependent, especially at low photon energies. Monte Carlo simulations have been used to determine the magnitude of the errors obtained if it is assumed that the deposition is homogeneous, when in fact it is not. Simulation for a germanium lung counting system consisting of four, 70 mm ...

journal_title：Environmental health perspectives

authors： Kramer GH

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) affects 71 million American adults and remains the leading cause of death in the United States and Europe. Despite studies that suggest that the development of CVD may be linked to intrauterine growth or early events in childhood, little direct experimental evidence supports the ...

journal_title：Environmental health perspectives

authors： Ng SP,Conklin DJ,Bhatnagar A,Bolanowski DD,Lyon J,Zelikoff JT

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:A critical question regarding the association between short-term exposure to ozone and mortality is the extent to which this relationship is confounded by ambient exposure to particles. OBJECTIVES:We investigated whether particulate matter < 10 and < 2.5 microm in aerodynamic diameter (PM(10) and PM(2.5)) i...

journal_title：Environmental health perspectives

authors： Bell ML,Kim JY,Dominici F

更新日期：2007-11-01 00:00:00

abstract：:To assess quantitatively the association between benzene and leukemia, we evaluated the rate of mortality experienced by a cohort occupationally exposed to benzene. Using data from historical air sampling surveys, we estimated the daily benzene exposure for each member of the cohort. The expected number of leukemia de...

journal_title：Environmental health perspectives

authors： Rinsky RA

更新日期：1989-07-01 00:00:00

abstract：:We have witnessed a tremendous increase in our knowledge of the molecular and biochemical mechanisms which underly the activities of the nervous system. Such knowledge is essential in order to determine the basic mechanisms involved in neurotoxic events. An overview of how neurotoxins could conceivably interfere with ...

journal_title：Environmental health perspectives

authors： Damstra T

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Cancer may be a stem cell (SC)-based disease involving formation of cancer SCs (CSCs) potentially arising from transformation of normal SCs. Cadmium has been linked to human pancreatic cancer. OBJECTIVE:We studied cadmium exposure of human pancreatic ductal epithelial (HPDE) cells and whether SCs may be tar...

journal_title：Environmental health perspectives

authors： Qu W,Tokar EJ,Kim AJ,Bell MW,Waalkes MP

更新日期：2012-09-01 00:00:00

abstract：:Fluorescence in situ hybridization with chromosome-specific composite DNA probes (chromosome painting) is a reliable and efficient method for detecting structural chromosome aberrations. Painting is now being used to quantify chromosome damage in many human populations. In one such study we evaluated 91 unexposed peop...

journal_title：Environmental health perspectives

authors： Tucker JD,Moore DH 2nd

更新日期：1996-05-01 00:00:00

abstract：:Traditional models of toxicity have relied on dissecting chemical action into pharmacokinetic and pharmacodynamic processes. However, the integration of genomic information with toxicology will enhance our basic understanding of these processes and significantly change the way we apply toxicological information to ris...

journal_title：Environmental health perspectives

authors： Thomas RS,Rank DR,Penn SG,Zastrow GM,Hayes KR,Hu T,Pande K,Lewis M,Jovanovich SB,Bradfield CA

更新日期：2002-12-01 00:00:00