Abstract:
BACKGROUND:Functional limitations are a major cause for needing care and institutionalization among older adults. Exposure to air pollution has been suggested to be associated with increased functional limitations in older people. OBJECTIVE:Our objective was to assess the association between air pollution and physical functioning in Dutch older adults. METHODS:We analyzed data on performance-based (walking speed, ability to rise from a chair, putting on and taking off a cardigan, balance test) and self-reported physical functioning for 1,762 participants of the Longitudinal Aging Study Amsterdam, who participated in measurement cycles performed in 2005/2006, 2008/2009, and 2011/2012. Annual average outdoor air pollution concentrations [nitrogen dioxide (NO2), nitrogen oxides (NOx), particulate matter with diameters ≤2.5μm (PM2.5), ≤10μm (PM10), and 2.5-10μm (PMcoarse), and PM2.5 absorbance] at the home address at the start of the first measurement cycle were estimated using land-use regression models. Analyses were performed using mixed models with random participant intercepts adjusting for potential confounders. RESULTS:Exposure to most air pollutants was associated with reduced performance-based physical functioning; for example, an interquartile range increase in NO2 exposure was associated with a 0.22 (95% confidence interval: 0.03, 0.42) lower performance test score in fully adjusted models, equivalent to the difference in performance score between participants who differed by 9 mo in age. Exposure to air pollution was generally not statistically significantly associated with self-reported functional limitations, and not associated with a faster decline in performance-based physical functioning over the study period. CONCLUSION:This study suggests that exposure to air pollution may adversely affect physical performance of older adults in the Netherlands. https://doi.org/10.1289/EHP2239.
journal_name
Environ Health Perspectjournal_title
Environmental health perspectivesauthors
de Zwart F,Brunekreef B,Timmermans E,Deeg D,Gehring Udoi
10.1289/EHP2239subject
Has Abstractpub_date
2018-01-19 00:00:00pages
017009issue
1eissn
0091-6765issn
1552-9924pii
EHP2239journal_volume
126pub_type
杂志文章abstract:BACKGROUND:In the United States, most of the treated sewage sludge (biosolids) is applied to farmland as a soil amendment. Critics suggest that rules regulating sewage sludge treatment and land application may be insufficient to protect public health and the environment. Neighbors of land application sites report illne...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1205470
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Thallium (Tl) is a highly toxic heavy metal widely present in the environment. Case reports have suggested that maternal exposure to high levels of Tl during pregnancy is associated with low birth weight (LBW), but epidemiological data are limited. OBJECTIVES:This study was designed to evaluate whether pren...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1409202
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:We reviewed the scientific background for the current health-based World Health Organization (WHO) guideline value for manganese in drinking water. DATA SOURCES AND EXTRACTION:The initial starting point was the background document for the development of the WHO's guideline value for manganese in drinking wat...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.10316
更新日期:2007-11-01 00:00:00
abstract::Concern about apparent increases in the prevalence of hypospadias--a congenital male reproductive-tract abnormality--in the 1960s to 1980s and the possible connection to increasing exposures to endocrine-disrupting chemicals have underlined the importance of effective surveillance of hypospadias prevalence in the popu...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.6398
更新日期:2004-03-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.10553
更新日期:2008-05-01 00:00:00
abstract::Uranium accumulates in bone, affects bone metabolism in laboratory animals, and when ingested in drinking water increases urinary excretion of calcium and phosphate, important components in the bone structure. However, little is known about bone effects of ingested natural uranium in humans. We studied 146 men and 142...
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更新日期:2005-01-01 00:00:00
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更新日期:1997-03-01 00:00:00
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更新日期:2005-10-01 00:00:00
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更新日期:2008-10-01 00:00:00
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更新日期:2020-06-01 00:00:00
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journal_title:Environmental health perspectives
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doi:10.1289/ehp.7039
更新日期:2004-11-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章
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更新日期:2004-09-01 00:00:00
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doi:10.1289/ehp.90-1519491
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doi:10.1289/ehp.02110197
更新日期:2002-02-01 00:00:00
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doi:10.1289/ehp.93101s2311
更新日期:1993-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1289/ehp.95103s8237
更新日期:1995-11-01 00:00:00
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更新日期:2003-04-01 00:00:00
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doi:10.1289/ehp.1205984
更新日期:2014-03-01 00:00:00
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doi:10.1289/ehp.108-a546a
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更新日期:1981-04-01 00:00:00
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更新日期:1979-06-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章
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更新日期:2009-02-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.1205092
更新日期:2013-01-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.834993
更新日期:1983-03-01 00:00:00
abstract::The lysosomes of several varieties of cells such as the tubular proximal cell of the kidney and the alveolar macrophage have the ability to concentrate and precipitate several elements inhaled in water-soluble form, usually as phosphate. The mechanism involved is attributed to the high acid phosphatase activity of lys...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.9297145
更新日期:1992-07-01 00:00:00
abstract::The association between ambient air pollution and adverse health effects, such as emergency room visits, hospitalizations, and mortality from respiratory and cardiovascular diseases, has been studied extensively in many countries, including Canada. Recently, studies conducted in China, the Czech Republic, and the Unit...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.6251
更新日期:2003-11-01 00:00:00
abstract::The review of over 800 references on aluminum (Al) published since the mid-fifties covers the occurrence of Al in soil, air, water, plants and food products, as well as air and water pollution problems. In addition, the existing quality criteria, the biology and toxicology of Al, and the therapeutic and medical uses a...
journal_title:Environmental health perspectives
pub_type: 杂志文章
doi:10.1289/ehp.7483
更新日期:1974-08-01 00:00:00
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journal_title:Environmental health perspectives
pub_type: 杂志文章,评审
doi:10.1289/ehp.8980199
更新日期:1989-03-01 00:00:00