An age of enlightenment for cilia: The FASEB summer research conference on the "Biology of Cilia and Flagella".

abstract：:A modification of the scrape-loading/dye transfer technique was used to study gap junctional communication along the anterior-posterior (A-P) axis of embryonic chick wing buds at an early stage of development (stage 20/21) when positional values along the A-P axis are being specified. Extensive intercellular transfer ...

journal_title：Developmental biology

authors： Coelho CN,Kosher RA

更新日期：1991-12-01 00:00:00

abstract：:Mutations in the XNP/ATR-X gene cause several X-linked mental retardation syndromes in humans. The XNP/ATR-X gene encodes a DNA-helicase belonging to the SNF2 family. It has been proposed that XNP/ATR-X might be involved in chromatin remodelling. The lack of a mouse model for the ATR-X syndrome has, however, hampered ...

journal_title：Developmental biology

authors： Cardoso C,Couillault C,Mignon-Ravix C,Millet A,Ewbank JJ,Fontés M,Pujol N

更新日期：2005-02-01 00:00:00

abstract：:Border Cells in the Drosophila ovaries are a useful genetic model for understanding the molecular events underlying epithelial cell motility. During stage 9 of egg chamber development they detach from neighboring stretched cells and migrate between the nurse cells to reach the oocyte. RNAi screening allowed us to iden...

journal_title：Developmental biology

authors： De Graeve FM,Van de Bor V,Ghiglione C,Cerezo D,Jouandin P,Ueda R,Shashidhara LS,Noselli S

更新日期：2012-08-01 00:00:00

abstract：:Vertebrate heart development requires specification of cardiac precursor cells, migration of cardiac progenitors as well as coordinated cell movements during looping and septation. DM-GRASP/ALCAM/CD166 is a member of the neuronal immunoglobulin domain superfamily of cell adhesion molecules and was recently suggested t...

journal_title：Developmental biology

authors： Gessert S,Maurus D,Brade T,Walther P,Pandur P,Kühl M

更新日期：2008-09-01 00:00:00

abstract：:Anuran amphibian embryos (Xenopus laevis and Rana dybowskii) are sensitive to novel gravitational fields. Under simulated weightlessness, (i) the location of the first horizontal cleavage furrow was shifted toward the vegetal pole at the eight-cell stage; (ii) the position of the blastocoel was more centered, and the ...

journal_title：Developmental biology

authors： Neff AW,Yokota H,Chung HM,Wakahara M,Malacinski GM

更新日期：1993-01-01 00:00:00

abstract：:Ovarian germ cell survival is dependent upon the formation of primordial follicles, which occurs during fetal life in the human. Activin contributes to germ cell proliferation and survival at this time. SMADs2 and 3 are central elements in the activin signalling pathway and thus indicate sites of activin action. We ha...

journal_title：Developmental biology

authors： Coutts SM,Childs AJ,Fulton N,Collins C,Bayne RA,McNeilly AS,Anderson RA

更新日期：2008-02-01 00:00:00

abstract：:HB-GAM (heparin-binding growth-associated molecule) is a secretory, extracellular matrix-associated protein that was isolated by screening for proteins that enhance neurite outgrowth in perinatal rat brain neurons. In the present study we have investigated the possible role of HB-GAM in cell proliferation in the devel...

journal_title：Developmental biology

authors： Szabat E,Rauvala H

更新日期：1996-08-25 00:00:00

abstract：:We describe mesendoderm morphogenesis during gastrulation in the frog Xenopus laevis and investigate the mechanics of these movements with tissue explants. When a dorsal marginal zone explant is plated onto fibronectin, the mesendoderm moves away from the dorsal axial tissues as an intact sheet. Mesendodermal cells wi...

journal_title：Developmental biology

authors： Davidson LA,Hoffstrom BG,Keller R,DeSimone DW

更新日期：2002-02-15 00:00:00

abstract：:The polypeptide sequence predicted from the Pem oncofetal gene cDNA contains a homeodomain most closely related to the paired class. Pem, paired class member orthodenticle, and the bicoid maternal gene product homeodomains all have lysine residues at a recognition helix position implicated in DNA-binding specificity. ...

journal_title：Developmental biology

authors： Rayle RE

更新日期：1991-07-01 00:00:00

abstract：:Soluble N-ethylmalameide-sensitive factor attachment protein receptor (SNARE) proteins are present in mammalian sperm and could be involved in critical membrane fusion events during fertilization, namely the acrosome reaction. Vesicle-associated membrane protein/synaptobrevin, a SNARE on the membrane of a vesicular ca...

journal_title：Developmental biology

authors： Ramalho-Santos J,Moreno RD,Sutovsky P,Chan AW,Hewitson L,Wessel GM,Simerly CR,Schatten G

更新日期：2000-07-01 00:00:00

abstract：:Mutations in the Bone Morphogenetic Protein (BMP) pathway are associated with a range of defects in skeletal formation. Genetic analysis of BMP signaling requirements is complicated by the presence of three partially redundant BMPs that are required for multiple stages of limb development. We generated an inducible al...

journal_title：Developmental biology

authors： Norrie JL,Lewandowski JP,Bouldin CM,Amarnath S,Li Q,Vokes MS,Ehrlich LIR,Harfe BD,Vokes SA

更新日期：2014-09-15 00:00:00

abstract：:The transforming growth factor-beta (TGF-beta) superfamily contains a variety of growth factors which all share common sequence elements and structural motifs. These proteins are known to exert a wide spectrum of biological responses on a large variety of cell types in both vertebrates and invertebrates. Many of them ...

journal_title：Developmental biology

authors： Balemans W,Van Hul W

更新日期：2002-10-15 00:00:00

abstract：:Boundary formation is an important mechanism of development and has been studied in a number of bilaterian model organisms where it is often controlled by Notch, FGF and Wnt signalling. Tissue boundaries are also formed in simple pre-bilaterian animals. The boundary between parent and bud during asexual reproduction i...

journal_title：Developmental biology

authors： Münder S,Käsbauer T,Prexl A,Aufschnaiter R,Zhang X,Towb P,Böttger A

更新日期：2010-08-01 00:00:00

abstract：:POSH (Plenty of SH3s) has distinct roles as a scaffold for specific c-Jun N-terminal kinase (JNK) signaling modules and as an E3 ubiquitin ligase. The physiological function of POSH remains unclear, however, and its possible involvement in developmental processes motivated the present study wherein the Xenopus ortholo...

journal_title：Developmental biology

authors： Kim GH,Park E,Han JK

更新日期：2005-10-01 00:00:00

abstract：:Cleft palate is one of the most common craniofacial congenital defects in humans. It is associated with multiple genetic and environmental risk factors, including mutations in the genes encoding signaling molecules in the sonic hedgehog (Shh) pathway, which are risk factors for cleft palate in both humans and mice. Ho...

journal_title：Developmental biology

authors： Li J,Yuan Y,He J,Feng J,Han X,Jing J,Ho TV,Xu J,Chai Y

更新日期：2018-09-01 00:00:00

abstract：:Initiation of transcription mediated by RNA polymerase II requires a number of transcription factors among which TFIID is the major core promoter recognition factor. TFIID is composed of highly conserved factors which include the TATA-binding protein (TBP) and about 14 TBP-associated factors (TAFs). Recently, the comp...

journal_title：Developmental biology

authors： Lago C,Clerici E,Dreni L,Horlow C,Caporali E,Colombo L,Kater MM

更新日期：2005-09-01 00:00:00

abstract：:beta-Catenin was originally identified biochemically as a protein that binds E-cadherin in cultured cells and that interaction was later shown to be essential for cadherin function. Independently, armadillo, the beta-catenin homolog in Drosophila melanogaster, was identified as a segment polarity gene necessary for th...

journal_title：Developmental biology

authors： Miller JR,McClay DR

更新日期：1997-12-15 00:00:00

abstract：:The lizards are evolutionarily the closest vertebrates to humans that demonstrate the ability to regenerate entire appendages containing cartilage, muscle, skin, and nervous tissue. We previously isolated PAX7-positive cells from muscle of the green anole lizard, Anolis carolinensis, that can differentiate into multin...

journal_title：Developmental biology

authors： Palade J,Djordjevic D,Hutchins ED,George RM,Cornelius JA,Rawls A,Ho JWK,Kusumi K,Wilson-Rawls J

更新日期：2018-01-15 00:00:00

abstract：:The inner ear, the sensory organ responsible for hearing and balance, contains specialized sensory and non-sensory epithelia arranged in a highly complex three-dimensional structure. To achieve this complexity, a tight coordination between morphogenesis and cell fate specification is essential during otic development....

journal_title：Developmental biology

authors： Vázquez-Echeverría C,Dominguez-Frutos E,Charnay P,Schimmang T,Pujades C

更新日期：2008-10-01 00:00:00

abstract：:Monoclonal antibodies highly selective for developmentally regulated antigens present in the cornea (Zak and Linsenmayer, Dev. Biol. 99, 373-381, 1983) have been used to immunohistochemically evaluate differentiation in intact chick corneas cultured on the chorioallantoic membrane (CAM) of host embryos. One antibody i...

journal_title：Developmental biology

authors： Zak NB,Linsenmayer TF

更新日期：1985-04-01 00:00:00

abstract：:The plasticity of nerve cells expressing the neuropeptide FMRFamide was examined in adult hydra. Using a whole-mount technique with indirect immunofluorescence, the spatial pattern of neurons showing FMRFamide-like immunoreactivity (FLI) was visualized. These neurons were located in the tentacles, hypostome, and pedun...

journal_title：Developmental biology

authors： Koizumi O,Bode HR

更新日期：1986-08-01 00:00:00

abstract：:We have examined the expression of mRNAs encoding five major neurotransmitter-synthesizing enzymes in MAH cells, a clonal cell line derived by retroviral immortalization of a rat embryonic sympathoadrenal progenitor cell. These mRNAs include tyrosine hydroxylase (TH), choline acetyltransferase (ChAT), tryptophan hydro...

journal_title：Developmental biology

authors： Vandenbergh DJ,Mori N,Anderson DJ

更新日期：1991-11-01 00:00:00

abstract：:It has been posited that animal development evolved from pre-existing mechanisms for regulating cell differentiation in the single celled and colonial ancestors of animals. Although the progenitors of animals cannot be studied directly, insights into their cell biology may be gleaned from comparisons between animals a...

journal_title：Developmental biology

authors： Dayel MJ,Alegado RA,Fairclough SR,Levin TC,Nichols SA,McDonald K,King N

更新日期：2011-09-01 00:00:00

abstract：:The adult fungiform taste papilla is a complex of specialized cell types residing in the stratified squamous tongue epithelium. This unique sensory organ includes taste buds, papilla epithelium and lateral walls that extend into underlying connective tissue to surround a core of lamina propria cells. Fungiform papilla...

journal_title：Developmental biology

authors： Liu HX,Ermilov A,Grachtchouk M,Li L,Gumucio DL,Dlugosz AA,Mistretta CM

更新日期：2013-10-01 00:00:00

abstract：:During digit development, the correct balance of chondrogenic signals ensures the recruitment of undifferentiated cells into the cartilage lineage or the maintenance of cells at the undifferentiated stage. WNT/β catenin maintains the pool of progenitor cells, whereas TGFβ signalling promotes cartilage differentiation ...

journal_title：Developmental biology

authors： Farrera-Hernández A,Marín-Llera JC,Chimal-Monroy J

更新日期：2021-01-01 00:00:00

abstract：:Pericellular proteolysis by ADAM family metalloproteinases has been widely implicated in cell signaling and development. We recently found that Xenopus ADAM13, an ADAM metalloproteinase, is required for activation of canonical Wnt signaling during cranial neural crest (CNC) induction by regulating a novel crosstalk be...

journal_title：Developmental biology

authors： Wei S,Xu G,Bridges LC,Williams P,Nakayama T,Shah A,Grainger RM,White JM,DeSimone DW

更新日期：2012-03-01 00:00:00

abstract：:The dysgenetic lens (dyl) mouse mutant has mutations in Foxe3, which inactivate DNA binding by the encoded forkhead transcription factor. Here we confirm, by targeted inactivation, that Foxe3 mutations are responsible for the dyl phenotype, which include loss of lens epithelium; a small, cataractic lens; and failure o...

journal_title：Developmental biology

authors： Blixt A,Landgren H,Johansson BR,Carlsson P

更新日期：2007-02-01 00:00:00

abstract：:Isotopes of a number of crustacean myofibrillar proteins have been identified with sodium dodecyl sulfate-polyacrylamide electrophoresis, and their distribution in muscles of the snapping shrimp has been examined. Fast-slow differences in distribution have been observed for myosin light chains and tropomyosin. In cont...

journal_title：Developmental biology

authors： Quigley MM,Mellon D Jr

更新日期：1984-11-01 00:00:00

abstract：:Although communications between mammalian oocytes and their surrounding granulosa cells mediated by the Kit-Kit ligand (KL, or stem cell factor, SCF) system have been proven to be crucial for follicular development, Kit downstream signaling pathways in mammalian oocytes are largely unknown. In this study, by using ova...

journal_title：Developmental biology

authors： Reddy P,Shen L,Ren C,Boman K,Lundin E,Ottander U,Lindgren P,Liu YX,Sun QY,Liu K

更新日期：2005-05-15 00:00:00

abstract：:The ability of Xenopus oocytes to undergo insulin- or insulin-like growth factor 1-induced meiotic maturation develops during oogenesis, with cells 1.0 mm in diameter or larger responding in a size-dependent manner. Since insulin-induced oocyte maturation was shown previously to be p21 ras-dependent, experiments were ...

journal_title：Developmental biology

authors： Davis D,Sadler SE

更新日期：1992-01-01 00:00:00