当前位置： SCI文献检索 > CELLULAR IMMUNOLOGY期刊下所有文献 > Anti-inflammatory effect of curcumin on mast cell-mediated allergic responses in ovalbumin-induced allergic rhinitis mouse.

Anti-inflammatory effect of curcumin on mast cell-mediated allergic responses in ovalbumin-induced allergic rhinitis mouse.

Abstract：

:Curcumin has commonly been used for the treatment of various allergic diseases. However, its precise anti-allergic rhinitis effect and mechanism remain unknown. In the present study, the effect of curcumin on allergic responses in ovalbumin (OVA)-induced allergic rhinitis mouse was investigated. We explored the effect of curcumin on the release of allergic inflammatory mediators, such as histamine, OVA-specific IgE, and inflammatory cytokines. Also, we found that curcumin improved rhinitis symptoms, inhibited the histopathological changes of nasal mucosa, and decreased the serum levels of histamine, OVA-specific IgE and TNF-α in OVA-induced allergic rhinitis mice. In addition, curcumin suppressed the production of inflammatory cytokines, such as TNF-α, IL-1β, IL-6 and IL-8. Moreover, curcumin significantly inhibited PMA-induced p-ERK, p-p38, p-JNK, p-Iκ-Bα and NF-κB. These findings suggest that curcumin has an anti-allergic effect through modulating mast cell-mediated allergic responses in allergic rhinitis, at least partly by inhibiting MAPK/NF-κB pathway.

journal_name

Cell Immunol

journal_title

Cellular immunology

authors

Zhang N,Li H,Jia J,He M

doi

10.1016/j.cellimm.2015.09.010

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

88-95

issue

1-2

eissn

0008-8749

issn

1090-2163

pii

S0008-8749(15)30022-8

journal_volume

298

pub_type

杂志文章

相关文献

CELLULAR IMMUNOLOGY文献大全
  • The CR2 receptor (CD21) shows increased expression in the more differentiated cells of an antigen-specific B cell line.

    abstract：:The complement receptor 2 (CR2; CD21), a 145,000 MW glycoprotein, has been useful as a marker of B lymphocyte maturation. It is expressed on the 1:13 monoclonal, EBV-transformed, B cell line which produces TNP-specific IgM-kappa and displays an in vitro capacity for differentiation. The line expresses the CD20+CD21+ p...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(90)90093-7

    authors： Pillemer SR,Tsokos GC,Barbieri SA,Balow JE,Golding B

    更新日期：1990-02-01 00:00:00

  • Selection of CD4+CD8+ thymocytes by complex formation with medulla-derived epithelial cells.

    abstract：:The role of lymphostromal complexes in T-cell differentiation is far from elucidated, mainly because a clear association of a particular stromal cell type with a distinct thymocyte subset has never been identified. Using an in vitro system, detecting the adherence of thymocytes to a thymic medullary epithelial cell li...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(90)90307-d

    authors： Hugo P,Potworowski EF

    更新日期：1990-03-01 00:00:00

  • Norepinephrine and serotonin content of the murine spleen: its relationship to lymphocyte beta-adrenergic receptor density and the humoral immune response in vivo and in vitro.

    abstract：:Numerous reports in the literature describe the effects of beta-adrenergic agonists and/or their second messenger cyclic AMP on in vitro and in vivo immune responses. The fact that the murine spleen receives rich adrenergic innervation and that the pharmacologic disruption of this innervation leads to altered immune r...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(88)90123-2

    authors： Fuchs BA,Campbell KS,Munson AE

    更新日期：1988-12-01 00:00:00

  • Suppression of experimental allergic encephalomyelitis in Lewis rats treated with myelin basic protein-liposome complexes: clinical, histopathological, and cell-mediated immunity correlates.

    abstract：:Guinea pig myelin basic protein (MBP) was inserted into phosphatidylserine liposomes and Lewis rats were injected by the intracardiac (ic) route with 75 microgram doses of MBP-liposomes according to various schedules. After challenge with 75 microgram guinea pig MBP in complete Freund's adjuvant, the rats were followe...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(84)90088-1

    authors： Strejan GH,Percy DH,St Louis J

    更新日期：1984-03-01 00:00:00

  • Differential effects of granulocyte/macrophage colony-stimulating factor (GM-CSF) in enhancing macrophage resistance to Legionella pneumophila vs Candida albicans.

    abstract：:It has been reported that granulocyte/macrophage colony-stimulating factor (GM-CSF), one of the hemopoietic growth factors which regulates the function of phagocytic cells, is a potent activator of cultured macrophages and induces antimicrobial activities as well as differentiation of precursor cells. In this study, w...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1996.1074

    authors： Yamamoto Y,Klein TW,Tomioka M,Friedman H

    更新日期：1997-02-25 00:00:00

  • IL-6 rescues the hyporesponsiveness of c-Rel deficient B cells independent of Bcl-xL, Mcl-1, and Bcl-2.

    abstract：:The hematopoietically restricted member of the NF-kappaB/Rel family, c-Rel, is essential for B cell survival and proliferation. Here we demonstrate that the production of the interleukins 6, 10, and 15 (IL-6, IL-10, and IL-15) are diminished in c-Rel(-/-) B lymphocytes. In a manner similar to that seen in IL-6(-/-) B ...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/s0008-8749(02)00513-0

    authors： Tumang JR,Hsia CY,Tian W,Bromberg JF,Liou HC

    更新日期：2002-05-01 00:00:00

  • Inhibition of experimental autoimmune thyroiditis in mice by anti-I-A antibodies.

    abstract：:Experimental autoimmune thyroiditis is induced in mice by immunization with thyroglobulin emulsified in Freund's complete adjuvant. The disease is characterized both by thyroid infiltration with mononuclear cells and by circulating thyroglobulin antibodies. The magnitude of the thyroid infiltration and the titer of th...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(87)90302-9

    authors： Vladutiu AO,Steinman L

    更新日期：1987-10-01 00:00:00

  • Notch signaling regulates CXCR4 expression and the migration of mesenchymal stem cells.

    abstract：:Mesenchymal stem cells (MSCs) have been used to repair injured tissues through immune-suppression and/or cell replace mechanisms. However, a significant barrier to MSC therapy is insufficient MSC engraftment in injured tissues after systemic administration. Here, we report that cell surface, total protein, and mRNA le...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2013.02.001

    authors： Xie J,Wang W,Si JW,Miao XY,Li JC,Wang YC,Wang ZR,Ma J,Zhao XC,Li Z,Yi H,Han H

    更新日期：2013-01-01 00:00:00

  • Nonrestricted cytotoxicity mediated by interleukin 2-expanded leukocytes is inhibited by anti-LFA-1 monoclonal antibodies (MoAb) but potentiated by anti-CD3 MoAb.

    abstract：:Previous results have shown that in addition to their ability to kill tumor cell lines, peripheral blood leukocytes (PBL) expanded in interleukin 2 (IL-2) can also destroy normal PBL targets. Cold target competition results show that PBL and tumor cells can be destroyed by the same population of IL-2-expanded leukocyt...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(87)90123-7

    authors： Chen BP,Malkovsky M,Hank JA,Sondel PM

    更新日期：1987-12-01 00:00:00

  • Role of lymphokines in regulation of macrophage differentiation.

    abstract：:The regulatory mechanism of guinea pig lymphokines was investigated in regard to differentiation of myeloid cells to macrophages. The Ml-cell line, established from a myeloid leukemia of an SL-strain mouse, was induced to differentiate in vitro into mature macrophages possessing Fc receptors and the ability to phagocy...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(83)90355-6

    authors： Onozaki K,Akagawa KS,Haga S,Miura K,Hashimoto T,Tokunaga T

    更新日期：1983-02-15 00:00:00

  • Thymocyte maturation following interaction with thymus-derived macrophages.

    abstract：:Murine C57BL/6 thymocytes were cultivated together with syngeneic thymus-derived macrophages (TDM phi) for up to 96 hr to determine whether TDM phi participate in thymocyte maturation. The expression level of H-2b and Thy-1.2 antigens served as thymocyte differentiation surface markers as analyzed by flow cytometry. I...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(91)90310-8

    authors： Zeira M,Gallily R,Stein I,Giloh H

    更新日期：1991-05-01 00:00:00

  • Engineered cells for costimulatory enhancement combined with IL-21 enhance the generation of PD-1-disrupted CTLs for adoptive immunotherapy.

    abstract：:Blockade of the immune cell checkpoint inhibitors programmed death 1 (PD-1) and programmed death-ligand 1 (PD-L1) has become a powerful tool in cancer treatment, which is effective across various solid cancer types and hematologic malignancies. Our previous studies showed that by reducing immune tolerance, clustered r...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2017.09.003

    authors： Shao J,Xu Q,Su S,Meng F,Zou Z,Chen F,Du J,Qian X,Liu B

    更新日期：2017-10-01 00:00:00

  • Anti-Fas antibody induces different types of cell death in the human histiocytic cell line, U937, and the human B cell line, B104: the role of single-strand DNA breaks and poly (ADP-ribosyl)ation in cell death.

    abstract：:We investigated the anti-Fas antibody-induced cell death in two different types of human cell lines, U937 and B104. IFN-gamma increased the surface expression of Fas antigen and susceptibility to anti-Fas Ab-induced cell death of B104 and U937 cells. Anti-Fas Ab-induced death of U937 and B104 cells required neither a ...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1994.1016

    authors： Sumimoto S,Ishigami T,Horiguchi Y,Yonehara S,Kanazashi S,Heike T,Katamura K,Mayumi M

    更新日期：1994-01-01 00:00:00

  • Ia- and IgG-Fc receptor-positive accessory cell sustains peripheral T lymphocyte but not thymocyte mitogenesis induced by OKT3 monoclonal antibody.

    abstract：:The proliferative responses of human peripheral blood mononuclear cells (PBL) and thymocytes to OKT3 monoclonal antibody have been investigated. The PBL response to OKT3 was maximal after 72 hr while that of thymocytes was inappreciable at all times measured. Unlike phytohemagglutinin, OKT3 was unable to elicit the mi...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(84)90105-9

    authors： Musiani P,Maggiano N,Aiello FB,Lauriola L,Ranelletti FO,Piantelli M

    更新日期：1984-04-01 00:00:00

  • Surface molecules essential for positive selection are retained but interfered in thymic epithelial cells after monolayer culture.

    abstract：:It has been reported that the three-dimensional structure of thymic epithelial cells (TECs) is responsible for thymic positive selection but that this ability disappears when TECs are cultured in monolayer. These results have supported the hypothesis that certain TEC-specific molecules are extinguished during monolaye...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.2001.1823

    authors： Sato T,Sato C,Suzuki D,Yoshida Y,Nunomura S,Matsumura T,Hozumi K,Habu S

    更新日期：2001-07-10 00:00:00

  • Suppression of experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein.

    abstract：:The oral administration of myelin basic protein (MBP) to Lewis rats prior to an encephalitogenic challenge resulted in total inhibition or a significant delay in the onset of experimental autoimmune encephalomyelitis (EAE). In vitro lymphocyte proliferative responses to MBP were significantly decreased in MBP-fed rats...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(88)90305-x

    authors： Bitar DM,Whitacre CC

    更新日期：1988-04-01 00:00:00

  • Modulation of the CD2 receptor and not disruption of the CD2/CD48 interaction is the principal action of CD2-mediated immunosuppression in the rat.

    abstract：:CD48, the murine homolog of human CD58, binds to CD2 in rats and mice. Whereas inhibition of CD2 signaling leads to profound immunosuppression, no information is available on CD48-targeted therapy in the rat. We could show that anti-CD2 treatment (OX34) efficiently inhibited TCR-driven as well as CD2-mediated prolifer...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1997.1204

    authors： Sido B,Otto G,Zimmermann R,Müller P,Meuer SC,Dengler TJ

    更新日期：1997-11-25 00:00:00

  • Tolerogenic vaccines: Targeting the antigenic and cytokine niches of FOXP3+ regulatory T cells.

    abstract：:FOXP3+ regulatory T cells (Tregs) constitute a critical barrier that enforces tolerance to both the self-peptidome and the extended-self peptidome to ensure tissue-specific resistance to autoimmune, allergic, and other inflammatory disorders. Here, we review intuitive models regarding how T cell antigen receptor (TCR)...

    journal_title：Cellular immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.cellimm.2020.104173

    authors： Mannie MD,DeOca KB,Bastian AG,Moorman CD

    更新日期：2020-09-01 00:00:00

  • Immunological and pathological consequences of mutations in both Fas and Fas ligand.

    abstract：:The lpr mutation in mice results in premature termination of transcription of the gene encoding the apoptosis-signaling receptor Fas. As a result, lpr mice develop severe lymphoproliferation and lupus-like autoantibodies. Growing evidence suggests that the lpr mutation is "leaky" and that low levels of Fas are express...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1998.1290

    authors： Weintraub JP,Godfrey V,Wolthusen PA,Cheek RL,Eisenberg RA,Cohen PL

    更新日期：1998-05-25 00:00:00

  • Role of the production of natural killer cell stimulatory factor (NKSF/IL-12) in the ability of B cell lines to stimulate T and NK cell proliferation.

    abstract：:We have previously used human Epstein Barr virus (EBV)-transformed B lymphoblastoid cell lines for the identification and purification of a novel cytokine, natural killer cell stimulatory factor (NKSF/IL-12), that has pleiotropic effects on human lymphocytes. B cell lines are also routinely employed as feeder cells fo...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(92)90322-g

    authors： Valiante NM,Rengaraju M,Trinchieri G

    更新日期：1992-11-01 00:00:00

  • Aging, sex, inflammation, frailty, and CMV and HIV infections.

    abstract：:Aging is characterized by significant immune remodeling at both cellular and molecular levels, also known as immunosenescence. Older adults often manifest a chronic low-grade inflammatory phenotype. These age-related immune system changes have increasingly been recognized not only to lead to immune functional decline ...

    journal_title：Cellular immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.cellimm.2019.104024

    authors： Leng SX,Margolick JB

    更新日期：2020-02-01 00:00:00

  • Apoptotic cell death induced by anti-IgM antibody and phorbol esters is inhibited by interleukin-4 in human B lymphoma cell line MBC-1.

    abstract：:The development of B cell tolerance is believed to involve negative signaling to B cells derived from the binding of antigen to the B cell surface immunoglobulin. B cell lines that receive negative signals may provide useful models for studying the mechanisms of B cell tolerance. We have established a human B lymphoma...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1994.1314

    authors： Komada Y,Zhang XL,Zhou YW,Tanaka S,Higashigawa M,Ido M,Sakurai M

    更新日期：1994-12-01 00:00:00

  • A cell permeant peptide containing the cytoplasmic tail sequence of Fc receptor type IIA reduces calcium signaling and phagolysosome formation in neutrophils.

    abstract：:Receptors for the Fc domain of IgG mediate target recognition, signal transduction, and effector functions including antibody-dependent cytolysis, phagocytosis, and phagolysosome formation. To better understand FcR-mediated functions and to identify potential therapeutic strategies, we employed cell-penetrating ("Troj...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2009.12.002

    authors： Clark AJ,Petty HR

    更新日期：2010-01-01 00:00:00

  • Induction of apoptosis in activated T cell blasts by suppressive macrophages: a possible immunotherapeutic approach for treatment of autoimmune disease.

    abstract：:Large suppressive macrophages (LSM) were induced by restimulating spleen cells from rats with experimental autoimmune myasthenia gravis (EAMG) in vitro, with the autoantigen acetylcholine receptor (AChR) in the presence of cyclosporine A. LSM, purified from these cultures, are extremely potent suppressors of AChR-stim...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1006/cimm.1998.1445

    authors： McIntosh KR,Drachman DB

    更新日期：1999-04-10 00:00:00

  • Transcutaneous immunization with hydrophilic recombinant gp100 protein induces antigen-specific cellular immune response.

    abstract：:The objective of this study was to evaluate the potential of transcutaneous immunization with tumor antigen to induce cell-mediated immunity. For this purpose, hydrophilic recombinant gp100 protein (HR-gp100) was topically applied on human intact skin in vitro, and used as a vaccine in a mouse model. We demonstrate th...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2010.09.003

    authors： Eisenberg G,Machlenkin A,Frankenburg S,Mansura A,Pitcovski J,Yefenof E,Peretz T,Lotem M

    更新日期：2010-01-01 00:00:00

  • Polysaccharide fraction of Agaricus brasiliensis avoids tumor-induced IL-10 production and changes the microenvironment of subcutaneous Ehrlich adenocarcinoma.

    abstract：:Subcutaneous Ehrlich tumor-bearing mice were treated with in situ inoculation of a beta-glucan-rich extract of Agaricus brasiliensis (ATF), which reduced tumor growth. Histopathological analysis showed that the tumor masses of control mice (Ehr) presented giant tumor cells and many mitotic figures whereas the tumor ti...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2009.01.002

    authors： Pinto AV,Martins PR,Romagnoli GG,Campanelli AP,Terezan AP,Filho ER,Ferreira da Eira A,Kaneno R

    更新日期：2009-01-01 00:00:00

  • Macrophage I-A/I-E expression and macrophage-stimulating lymphokines in murine lupus.

    abstract：:Seeking common abnormalities in mice genetically predisposed to lupus-like autoimmune disease, we investigated (1) the ontogeny of Ia antigens (I-A/I-E) on the surfaces of resident peritoneal macrophages (rpM phi) of lupus and normal mice, (2) spontaneous and lectin-induced in vitro production of M phi-stimulating fac...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(84)90133-3

    authors： Kofler R,Schreiber RD,Dixon FJ,Theofilopoulos AN

    更新日期：1984-08-01 00:00:00

  • Induction of CD8+ suppressor T cells by treatment with DMBA and TPA in vitro.

    abstract：:Antigen-nonspecific CD8+ T suppressor cells, which suppressed delayed-type hypersensitivity (DTH) against sheep red blood cells in BALB/c mice, were induced by incubating spleen cells from mice treated with 7,12-dimethylbenz[a]anthracene (DMBA), a tumor initiator, with 12-O-tetradecanoylphorbol 13-acetate (TPA), a tum...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(91)90167-a

    authors： Negoro T,Iinuma F,Watanabe M

    更新日期：1991-12-01 00:00:00

  • Effect of a local immune reaction on peripheral blood polymorphonuclear neutrophil microbicidal function: studies with fungal targets.

    abstract：:Peripheral blood polymorphonuclear neutrophils (PMN) from mice immunized with Blastomyces dermatitidis and then stimulated locally (intraperitoneally, ip) with B. dermatitidis antigen had enhanced killing of B. dermatitidis in vitro (54.4 +/- 19.49 of inoculum) compared to nonimmune mice (32.7 +/- 8.7%; P less than 0....

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/0008-8749(87)90111-0

    authors： Morrison CJ,Brummer E,Stevens DA

    更新日期：1987-11-01 00:00:00

  • Dendritic cells from HIV-1 infected individuals are less responsive to toll-like receptor (TLR) ligands.

    abstract：:We compared TLR responsiveness in PBMC from HIV-1-infected and uninfected individuals using the TLR agonists: TLR7 (3M-001), TLR8 (3M-002), and TLR7/8 (3M-011). Activation and maturation of plasmacytoid dendritic cells (pDC) were measured by evaluating CD86, CD40, and CD83 expression and myeloid dendritic cell (mDC) a...

    journal_title：Cellular immunology

    pub_type： 杂志文章

    doi：10.1016/j.cellimm.2008.01.007

    authors： Martinson JA,Roman-Gonzalez A,Tenorio AR,Montoya CJ,Gichinga CN,Rugeles MT,Tomai M,Krieg AM,Ghanekar S,Baum LL,Landay AL

    更新日期：2007-11-01 00:00:00