Development and in vitro/in vivo Evaluation of a Silastic Intravaginal Ring for Mifepristone Delivery.

abstract：:Manjisthadi churna has been traditionally used in the Ayurvedic system of medicine and by traditional medical practices of India to treat hyperlipidemia. A rapid, simple and accurate method with high performance thin layer chromatography has been developed to standardised Manjisthadi churna using rubiadin, sennoside a...

journal_title：Indian journal of pharmaceutical sciences

authors： Patel VR,Patel RK

更新日期：2013-01-01 00:00:00

abstract：:The petroleum ether leaf extract of Ficus krishnae has been evaluated for the management of diabetes in alloxan induced diabetic rats. Phytochemical screening of the leaf extract for various chemical compounds has also been carried out. Leaf extract was administered continuously for 21 days orally at a dose of 200 mg/...

journal_title：Indian journal of pharmaceutical sciences

authors： Sidhu MC,Sharma T

更新日期：2014-07-01 00:00:00

abstract：:Alpinia officinarum is a rhizome belonging to the family zingeberaeceae. Hydro alcoholic extract by hot and cold maceration and methanol extract by percolation process Qualitative phytochemical analysis of extract of Alpinia officinarum rhizome showed a majority of the compound including tannins, alkaloids, flavonoids...

journal_title：Indian journal of pharmaceutical sciences

authors： Srividya AR,Dhanabal SP,Misra VK,Suja G

更新日期：2010-01-01 00:00:00

abstract：:Gastroretentive bimodal drug delivery systems of lamotrigine were developed using immediate release and extended release segments incorporated in a hydroxypropyl methylcellulose capsule and in vitro and in vivo evaluations were conducted. In vivo radiographic studies were carried out for the optimized formulation in h...

journal_title：Indian journal of pharmaceutical sciences

authors： Poonuru RR,Gonugunta CS

更新日期：2014-11-01 00:00:00

abstract：:Ethyl naphtho[2,1-b]furan-2-carboxylate (2) on reaction with hydrazine hydrate in presence of acid catalyst in ethanol medium affords naphtho[2,1-b]furan-2-carbohydrazide (3). The reaction of substituted acetophenones (4a-c) with aromatic aldehydes (5a-e) produces chalcones (6a-o) via the Claisen condensation. The rea...

journal_title：Indian journal of pharmaceutical sciences

authors： Kumaraswamy MN,Chandrashekhar C,Shivakumar H,Prathima Mathias DA,Mahadevan KM,Vaidya VP

更新日期：2008-11-01 00:00:00

abstract：:Crystal form can be crucial to the performance of a dosage form. This is especially true for compounds that have intrinsic barriers to drug delivery, such as low aqueous solubility, slow dissolution in gastrointestinal media, low permeability and first-pass metabolism. The nature of the physical form and formulation t...

journal_title：Indian journal of pharmaceutical sciences

authors： Yadav AV,Shete AS,Dabke AP,Kulkarni PV,Sakhare SS

更新日期：2009-07-01 00:00:00

abstract：:A series of novel isatine-sulphonamide derivatives have been synthesized by combining isatin derivatives with sulphonamides. The structure of the synthesized compounds were elucidated by spectral analysis (IR, NMR and Mass). Investigation of anti-HIV activity was done against HIV-1(IIIB) in MT-4 cells and HIV integras...

journal_title：Indian journal of pharmaceutical sciences

authors： Selvam P,Murugesh N,Chandramohan M,Debyser Z,Witvrouw M

更新日期：2008-11-01 00:00:00

abstract：:Antianthelmintic activity of successive extracts (chloroform, acetone, ethanol and aqueous) of Nauclea orientalis leaves were evaluated separately on adult Indian earthworm (Pheretima posthuma) and compared with that of albendazole. It was found that the extracts exhibited, respectively dose-dependent action and inhib...

journal_title：Indian journal of pharmaceutical sciences

authors： Raghavamma ST,Rao NR

更新日期：2010-07-01 00:00:00

abstract：:Essential oils extracted from flower petals of palmarosa (Cymbopogon martini), evening primrose (Primula rosea), lavender (Lavandula angustifolia) and tuberose (Polianthus tuberosa) were tested for their antibacterial activities against gram-positive and gram-negative bacteria. Different concentrations of each essenti...

journal_title：Indian journal of pharmaceutical sciences

authors： Lodhia MH,Bhatt KR,Thaker VS

更新日期：2009-03-01 00:00:00

abstract：:Present study reports the development and validation of a simultaneous estimation of metformin and gliclazide in human plasma using supercritical fluid chromatography followed by tandem mass spectrometry. Acetonitrile:water (80:20) mixture was used as a mobile phase along with liquid CO(2) in supercritical fluid chrom...

journal_title：Indian journal of pharmaceutical sciences

authors： Agrawal YK,Gogoi PJ,Manna K,Bhatt HG,Jain VK

更新日期：2010-01-01 00:00:00

abstract：:A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of bicalutamide in bulk and pharmaceutical dosage forms. Bicalutamide shows maximum absorbance at 272 nm with molar absorptivity of 2.3399×10(4) l/mol/cm. Beer's law was obeyed in the concentration range of...

journal_title：Indian journal of pharmaceutical sciences

authors： Sancheti PP,Vyas VM,Shah M,Karekar P,Pore YV

更新日期：2008-11-01 00:00:00

abstract：:The rising problem of resistance to most commonly used antimalarials remains a major challenge in the control of malaria suggesting the need for new antimalarial agents. This work explores the antiplasmodial potential of ethanol extract of Russelia equisetiformis in chloroquine Plasmodium berghei infected mice. Swiss ...

journal_title：Indian journal of pharmaceutical sciences

authors： Ojurongbe O,Ojo JA,Adefokun DI,Abiodun OO,Odewale G,Awe EO

更新日期：2015-07-01 00:00:00

abstract：:The effect of some physical and nutritional parameters were studied for the optimum production of extracellular enzyme hyaluronidase employing Streptococcus mitis MTCC*2695 by submerged fermentation. The effects of initial pH, incubation temperature and time, inoculum level and age of inoculum were studied. The maximu...

journal_title：Indian journal of pharmaceutical sciences

authors： Sahoo S,Panda PK,Mishra SR,Nayak A,Dash SK,Ellaiah P

更新日期：2008-09-01 00:00:00

abstract：:It is now known that vitamin D deficiency is a worldwide health problem. In our country, as food fortification is lacking, supplementation with pharmaceutical preparations is the only means of treatment of vitamin D deficiency. We aimed to study the composition and availability of various vitamin D preparations in the...

journal_title：Indian journal of pharmaceutical sciences

authors： Lhamo Y,Chugh PK,Tripathi CD

更新日期：2016-01-01 00:00:00

abstract：:The aim of the present study was to monitor adverse drug reactions associated with antihypertensive drugs. The study was conducted in medicine out patient department of 150-bed Majeedia Hospital at Hamdard University Campus in New Delhi. The study was conducted by way of one to one patient interview by a registered ph...

journal_title：Indian journal of pharmaceutical sciences

authors： Hussain A,Aqil M,Alam MS,Khan MR,Kapur P,Pillai KK

更新日期：2009-05-01 00:00:00

abstract：:A simple accurate, sensitive and reproducible spectrofluorimetric method was developed for the analysis of duloxetine hydrochloride in pure and pharmaceutical dosage form. Duloxetine hydrochloride showed strong native fluorescence in 0.05 M acetic acid having excitation at 225 nm and emission at 340 nm. Effect of diff...

journal_title：Indian journal of pharmaceutical sciences

authors： Prabu SL,Shahnawaz S,Kumar CD,Shirwaikar A

更新日期：2008-07-01 00:00:00

abstract：:The antihyperlipidemic activity of resinoids of guggul (Commiphora mukul/Commiphora wightii), belonging to family Burseraceae (Genus: Commiphora), collected from different parts of India (Gujarat, Madhya Pradesh and Rajasthan), was studied on cholesterol-rich high fat diet-induced model of hyperlipidemia in rats. The ...

journal_title：Indian journal of pharmaceutical sciences

authors： Siddiqui MZ,Mazumder PM

更新日期：2012-09-01 00:00:00

abstract：:The formulations consisting of a hydrophilic and hydrophobic material were investigated for effect on drug-release pattern from the matrices. Gum damar and gum copal being water-insoluble were used to study the efficiency of combined matrices to sustain the release of drug. Hydroxypropyl methylcellulose K100M and dicl...

journal_title：Indian journal of pharmaceutical sciences

authors： Fulbandhe VM,Jobanputra CR,Wadher KJ,Umekar MJ,Bhoyar GS

更新日期：2012-05-01 00:00:00

abstract：:A gradient reversed phase HPLC method was developed and validated for the analysis of related substances in zonisamide (1,2-benzisoxazole-3-methanesulfonamide), using a Waters Symmetry C8 (150*3.9 mm) column with a flow rate of 1.0 ml/min and detection at 280 nm. The mobile phase component A consisted of a mixture of ...

journal_title：Indian journal of pharmaceutical sciences

authors： Vijayakumar EK,Dhore DM,Kumar M

更新日期：2009-09-01 00:00:00

abstract：:A simple, rapid, reliable, robust and optimized reversed phase high performance liquid chromatographic method for simultaneous estimation of doxycycline hyclate and curcumin was successfully developed and validated as per International Conference on Harmonization guidelines. The objective was achieved in terms of well...

journal_title：Indian journal of pharmaceutical sciences

authors： Dhal C,Ahmad FJ,Chauhan A,Jyothi M,Singh RM,Saini PK,Mathur SC,Singh GN

更新日期：2015-11-01 00:00:00

abstract：:A simple, accurate and precise spectrophotometric method has been developed for simultaneous estimation of escitalopram oxalate and clonazepam in combined dosage form. Simultaneous equation method is employed for simultaneous determination of escitalopram oxalate and clonazepam from combined dosage forms. In this meth...

journal_title：Indian journal of pharmaceutical sciences

authors： Kakde RB,Satone DD

更新日期：2009-11-01 00:00:00

abstract：:A few flavanones were synthesised by cyclisation of corresponding 3-(heteroaryl)-1(2-hydroxyphenyl) prop-2-en-1-one with sodium acetate in alcohol-water and evaluated for activity. Synthesised compounds were assayed for their in vitro anticancer activity against three human cancer cell lines, mammary adenocarcinoma (M...

journal_title：Indian journal of pharmaceutical sciences

authors： Murti Y,Mishra P

更新日期：2014-03-01 00:00:00

abstract：:Tuberculosis is one of the major public health problems faced globally. Resistance of Mycobacterium tuberculosis to antitubercular agents has called for an urgent need to investigate newer drugs to combat tuberculosis. Garlic (Allium sativum) is an edible plant which has generated a lot of curiosity throughout human h...

journal_title：Indian journal of pharmaceutical sciences

authors： Viswanathan V,Phadatare AG,Mukne A

更新日期：2014-05-01 00:00:00

abstract：:Breast cancer is the foremost common malignancy among the female population around the world. Female breast cancer incidence rates have increased since 1980, slowed in 1990, the rate of increase have leveled off since 2001. In spite of the advances in the early detection, treatment, surgery and radiation support, almo...

journal_title：Indian journal of pharmaceutical sciences

authors： Mohan A,Ponnusankar S

更新日期：2013-05-01 00:00:00

abstract：:Mebeverine hydrochloride is known to suffer from extensive first pass effect. In an attempt to improve its oral bioavailability and possibility to restrict its absorption only to the colon, mebeverine microspheres were prepared by emulsion solvent evaporation method. Four formulations were prepared with varying drug a...

journal_title：Indian journal of pharmaceutical sciences

authors： Dandagi PM,Mastiholimath VS,Gadad AP,Kulkarni AR,Konnur BK

更新日期：2009-07-01 00:00:00

abstract：:A derivative UV spectrophotometric and a reversed phase high-performance liquid chromatographic method for the determination of ciprofibrate in tablets was developed. The first-order derivative UV spectrophotometric method was found to be accurate with 100.57±0.97 recovery and precise with a coefficient of variation o...

journal_title：Indian journal of pharmaceutical sciences

authors： Jain PS,Jivani HN,Khatal RN,Surana SJ

更新日期：2012-03-01 00:00:00

abstract：:A simple, reproducible and efficient reverse phase high performance liquid chromatographic method was developed for simultaneous determination of valsartan and hydrochlorothiazide in tablets. A column having 200 x 4.6 mm i.d. in isocratic mode with mobile phase containing methanol:acetonitrile:water:isopropylalcohol (...

journal_title：Indian journal of pharmaceutical sciences

authors： Tian DF,Tian XL,Tian T,Wang ZY,Mo FK

更新日期：2008-05-01 00:00:00

abstract：:WHO reports estimate poisoning as one of the most common causes of increased morbidity and mortality rate world-wide. Various agents such as pesticides, drugs have been used for intentional and accidental poisoning in different countries. In the Indian scenario, pesticides are the most commonly used poisoning agents. ...

journal_title：Indian journal of pharmaceutical sciences

authors： Jesslin J,Adepu R,Churi S

更新日期：2010-09-01 00:00:00

abstract：:A simple, rapid, specific and sensitive liquid chromatography tandem mass spectrometric method has been developed and validated for the determination of doxycycline from the human plasma. Doxycycline is extracted from human plasma by solid phase extraction. Demeclocycline was used as an internal standard. Detection wa...

journal_title：Indian journal of pharmaceutical sciences

authors： Krishna AC,Sathiyaraj M,Saravanan RS,Chelladurai R,Vignesh R

更新日期：2012-11-01 00:00:00

abstract：:The effectiveness of liposome-mediated gene transfer methods hinges, in part, on the nature of the interaction between the DNA cargo and the liposomes. Here we have examined the effect of quaternization of the cytofectin cationic head group on this interaction and the effect of concentration of the biocompatible, prot...

journal_title：Indian journal of pharmaceutical sciences

authors： Daniels A,Noor-Mahomed N,Singh M,Ariatti M

更新日期：2011-07-01 00:00:00