Newer therapies for the treatment of metastatic breast cancer: a clinical update.

abstract：:A simple, accurate and sensitive spectroscopic method has been proposed for the assay of ciprofloxacin in tablet by least square treatment of fourier transform infrared spectrometric data obtained at the wavenumber corresponding to the carbonyl group centered at 1707 cm(-1). The method involves the extraction of the a...

journal_title：Indian journal of pharmaceutical sciences

authors： Pandey S,Pandey P,Tiwari G,Tiwari R,Rai AK

更新日期：2012-01-01 00:00:00

abstract：:This study was designed to evaluate the neuroprotective activity of ethanol extract of Pongamia pinnata stem bark in monosodium glutamate-induced neurotoxicity in rats. Neurotoxicity was induced by intraperitoneal injection of monosodium glutamate 2 g per kg body weight daily for 7 days. Ethanol extract of Pongamia pi...

journal_title：Indian journal of pharmaceutical sciences

authors： Swamy AH,Patel NL,Gadad PC,Koti BC,Patel UM,Thippeswamy AH,Manjula DV

更新日期：2013-11-01 00:00:00

abstract：:A simple HPLC method was developed and validated for the quantification of zanamivir in permeability studies using Caco-2 cell culture model. Chromatographic resolution was achieved using 98% (v/v) ultrapure water and 2% (v/v) acetonitrile as mobile phase with flow rate of 0.5 ml/min on a BDS Hypersil Cyano column (le...

journal_title：Indian journal of pharmaceutical sciences

authors： Boonyapiwat B,Sarisuta N,Ma Y,Steventon GB

更新日期：2011-09-01 00:00:00

abstract：:A series of novel isatine-sulphonamide derivatives have been synthesized by combining isatin derivatives with sulphonamides. The structure of the synthesized compounds were elucidated by spectral analysis (IR, NMR and Mass). Investigation of anti-HIV activity was done against HIV-1(IIIB) in MT-4 cells and HIV integras...

journal_title：Indian journal of pharmaceutical sciences

authors： Selvam P,Murugesh N,Chandramohan M,Debyser Z,Witvrouw M

更新日期：2008-11-01 00:00:00

abstract：:The present work describes a simple, precise and accurate HPLC method for estimation of montelukast sodium in bulk and in tablet dosage form. The separation was achieved by using octadecylsilane column (C18) and acetonitrile:1 mM sodium acetate adjusted to pH 6.3 with acetic acid in proportion of 90:10 v/v as mobile p...

journal_title：Indian journal of pharmaceutical sciences

authors： Singh RM,Saini PK,Mathur SC,Singh GN,Lal B

更新日期：2010-03-01 00:00:00

abstract：:Aqueous extract of leaves of Nelumbo nucifera was investigated on acute stress (immobilization stress)-induced biochemical alterations in Swiss mice. The animals were also subjected to acute physical stress (swimming endurance test) and acute chemical stress (writhing test) to gauge the antistress potential of the ext...

journal_title：Indian journal of pharmaceutical sciences

authors： Kulkarni MP,Juvekar AR

更新日期：2008-05-01 00:00:00

abstract：:The aim of this research was to investigate the technique for preparation of coated valproic acid and sodium valproate sustained-release matrix tablets. Different diluents were tested and selected as the effective absorbent for oily valproic acid. Effect of the amount of absorbent and hydroxypropylmethylcellulose on d...

journal_title：Indian journal of pharmaceutical sciences

authors： Phaechamud T,Mueannoom W,Tuntarawongsa S,Chitrattha S

更新日期：2010-03-01 00:00:00

abstract：:A gradient reversed phase HPLC method was developed and validated for analysis of betamethasone dipropionate, its related substances and degradation products, using Altima C(18) column (250×4.6 mm, 5 μm) with a flow rate of 1.0 ml/min and detection wavelength of 240 nm. The mobile phase A is a mixture of water, tetrah...

journal_title：Indian journal of pharmaceutical sciences

authors： Vairale AS,Sivaswaroop P,Bandana S

更新日期：2012-03-01 00:00:00

abstract：:The objective of this investigation was to prepare the shellac wax matrix tablets by fusion and molding technique incorporated with Lutrol in different ratios to modify the hydrophobicity of matrix tablet. The matrix tablets with single drug were loaded either with propranolol hydrochloride or hydrochlorothiazide as h...

journal_title：Indian journal of pharmaceutical sciences

authors： Phaechamud T,Choncheewa C

更新日期：2015-01-01 00:00:00

abstract：:A simple, rapid, specific and sensitive liquid chromatography tandem mass spectrometric method has been developed and validated for the determination of doxycycline from the human plasma. Doxycycline is extracted from human plasma by solid phase extraction. Demeclocycline was used as an internal standard. Detection wa...

journal_title：Indian journal of pharmaceutical sciences

authors： Krishna AC,Sathiyaraj M,Saravanan RS,Chelladurai R,Vignesh R

更新日期：2012-11-01 00:00:00

abstract：:Pyrazinamide, a highly specific agent against Mycobacterium tuberculosis is used as first-line drug to treat tuberculosis. The current work aims to formulate polymeric nanoparticles based drug delivery system to sustain the release profile and reduce the dosing frequency of pyrazinamide. Further aim was to target the ...

journal_title：Indian journal of pharmaceutical sciences

authors： Varma JN,Kumar TS,Prasanthi B,Ratna JV

更新日期：2015-05-01 00:00:00

abstract：:Fast dissolving tablets of clonazepam were prepared by sublimation method with a view to enhance patient compliance. A 3(2) full factorial design was applied to investigate the combined effect of two formulation variables: amount of croscarmellose sodium and camphor. Croscarmellose sodium (2-8% w/w) was used as superd...

journal_title：Indian journal of pharmaceutical sciences

authors： Shirsand SB,Suresh S,Kusumdevi V,Swamy PV

更新日期：2011-09-01 00:00:00

abstract：:The study was undertaken to evaluate various aspects of self-medication in medical students. A prospective, cross-sectional, questionnaire-based study was carried out among 488 medical students selected by simple random sampling from January 2013 to June 2013. Data was collected and analyzed for counts and percentage....

journal_title：Indian journal of pharmaceutical sciences

authors： Kasulkar AA,Gupta M

更新日期：2015-03-01 00:00:00

abstract：:Alpinia officinarum is a rhizome belonging to the family zingeberaeceae. Hydro alcoholic extract by hot and cold maceration and methanol extract by percolation process Qualitative phytochemical analysis of extract of Alpinia officinarum rhizome showed a majority of the compound including tannins, alkaloids, flavonoids...

journal_title：Indian journal of pharmaceutical sciences

authors： Srividya AR,Dhanabal SP,Misra VK,Suja G

更新日期：2010-01-01 00:00:00

abstract：:The results of our previous investigations on extracts of selected marine algae showed that Caulerpa peltata and Padina gymnospora had more promising antiproliferative and antioxidant activities than Gelidiella acerosa and Sargassum wightii. Based on these results, the more active chloroform extract of C. peltata and ...

journal_title：Indian journal of pharmaceutical sciences

authors： Murugan K,Iyer VV

更新日期：2014-11-01 00:00:00

abstract：:Pueraria tuberosa is known for its therapeutic potentials in cardiovascular disorders, but its effect in angiogenesis has not been studied so far. In this study, a computational approach has been applied to elucidate the role of the phytochemicals in inhibition of angiogenesis through modulation of vascular endothelia...

journal_title：Indian journal of pharmaceutical sciences

authors： Asthana S,Agarwal T,Singothu S,Samal A,Banerjee I,Pal K,Pramanik K,Ray SS

更新日期：2015-07-01 00:00:00

abstract：:The present study evaluated the in vitro antioxidant potential of different parts of Oroxylum indicum. 2,2-diphelyl 1-picrylhydrazyl (DPPH), nitric oxide, superoxide anion and hydroxyl radical scavenging potential and reductive ability assay of methanol extract of different parts i.e. root, root bark, stem, stem bark,...

journal_title：Indian journal of pharmaceutical sciences

authors： Mishra SL,Sinhamahapatra PK,Nayak A,Das R,Sannigrahi S

更新日期：2010-03-01 00:00:00

abstract：:A novel, efficient and simple approach for soy phosphatidylcholine analysis according to its fatty acid composition was studied with reverse-phase high-performance liquid chromatography. The reverse-phase high-performance liquid chromatography analysis was performed isocratically using UV detector and simple mobile ph...

journal_title：Indian journal of pharmaceutical sciences

authors： Jangle RD,Galge RV,Patil VV,Thorat BN

更新日期：2013-05-01 00:00:00

abstract：:Ethyl naphtho[2,1-b]furan-2-carboxylate (2) on reaction with hydrazine hydrate in presence of acid catalyst in ethanol medium affords naphtho[2,1-b]furan-2-carbohydrazide (3). The reaction of substituted acetophenones (4a-c) with aromatic aldehydes (5a-e) produces chalcones (6a-o) via the Claisen condensation. The rea...

journal_title：Indian journal of pharmaceutical sciences

authors： Kumaraswamy MN,Chandrashekhar C,Shivakumar H,Prathima Mathias DA,Mahadevan KM,Vaidya VP

更新日期：2008-11-01 00:00:00

abstract：:Gastroretentive bimodal drug delivery systems of lamotrigine were developed using immediate release and extended release segments incorporated in a hydroxypropyl methylcellulose capsule and in vitro and in vivo evaluations were conducted. In vivo radiographic studies were carried out for the optimized formulation in h...

journal_title：Indian journal of pharmaceutical sciences

authors： Poonuru RR,Gonugunta CS

更新日期：2014-11-01 00:00:00

abstract：:Various (4-substituted) phenyl-3-β-[(N-benzenesulphonyl/tosyl)-4-(un)substituted anilino]propionylamido-1,3-thiazolidine-4-ones (3a-x) and 1-β-[(N-benzenesulphonyl/tosyl)-4-(un)substituted anilino]-propionylamido-3-chloro-4-(4-substituted)phenyl-azetidin-2-ones (4a-x) have been synthesised by the cyclocondensation of ...

journal_title：Indian journal of pharmaceutical sciences

authors： Desai SR,Laddi UV,Bennur RS,Bennur SC

更新日期：2011-07-01 00:00:00

abstract：:It is now known that vitamin D deficiency is a worldwide health problem. In our country, as food fortification is lacking, supplementation with pharmaceutical preparations is the only means of treatment of vitamin D deficiency. We aimed to study the composition and availability of various vitamin D preparations in the...

journal_title：Indian journal of pharmaceutical sciences

authors： Lhamo Y,Chugh PK,Tripathi CD

更新日期：2016-01-01 00:00:00

abstract：:A reverse phase high performance liquid chromatographic method was developed for the simultaneous estimation of atorvastatin calcium and fenofibrate in tablet formulation. The separation was achieved by Luna C18 column and methanol:acetate buffer pH 3.7 (82:18 v/v) as mobile phase, at a flow rate of 1.5 ml/min. Detect...

journal_title：Indian journal of pharmaceutical sciences

authors： Jain N,Raghuwanshi R,Jain D

更新日期：2008-03-01 00:00:00

abstract：:A simple, sensitive and reproducible method was developed and validated for the simultaneous estimation of diethylcarbamazine and levocetirizine in its tablet formulation by reverse phase high performance liquid chromatography using Waters1515 HPLC with UV detector at the λ(max) of 224 nm, using Princeton Sphere-100 C...

journal_title：Indian journal of pharmaceutical sciences

authors： Reddy JM,Jeyaprakash MR,Madhuri K,Meyyanathan SN,Elango K

更新日期：2011-05-01 00:00:00

abstract：:In the present study, 2,5-disubstituted-1,3,4-oxadiazoles (3a-o) have been synthesized by the condensation of 4-methoxybenzohydrazide (1) with different aromatic acids (2a-o) in presence of phosphoryl chloride. The structural assignment of this compound (3a-o) has been made on the basis of elemental analysis, UV, IR, ...

journal_title：Indian journal of pharmaceutical sciences

authors： Nagalakshmi G

更新日期：2008-01-01 00:00:00

abstract：:A stability-indicating reversed-phase liquid chromatographic method has been developed and validated for simultaneous determination of losartan potassium and ramipril. Separations were achieved using a C(18) column with mobile phase consisting of acetonitrile and (0.2% v/v, pH 2.5) aqueous trifluoroacetic acid (45:55,...

journal_title：Indian journal of pharmaceutical sciences

authors： Kollipara S,Bende G,Bansal Y,Saha R

更新日期：2012-05-01 00:00:00

abstract：:Mitochondrial sodium calcium exchange inhibitors are novel agents in the treatment of type-II diabetes due to their glucose dependent efficacy. While the compounds of this class are expected to correct hyperglycemia, they do not lower basal blood glucose level, thus avoiding the serious consequences of hypoglycemia. T...

journal_title：Indian journal of pharmaceutical sciences

authors： Dasoondi AS,Singh V,Voleti SR,Tiwari M

更新日期：2008-03-01 00:00:00

abstract：:A simple, precise, and accurate isocratic reversed-phase (RP) stability-indicating HPLC assay method was developed and validated for determination of Aripiprazole in bulk and solid pharmaceutical dosage form. A reversed-phase C8 (250×4.0 mm, 5 μm particle size) column for HPLC and C8 (50×2.1mm, 1.7 μm particle size) f...

journal_title：Indian journal of pharmaceutical sciences

authors： Thakkar RS,Saravaia HT,Ambasana MA,Kaila HO,Shah AK

更新日期：2011-07-01 00:00:00

abstract：:In the present study, the effect of 2-hydroxy-4-methoxy benzoic acid isolated from roots of Hemisdesmus indicus on the erythrocyte membrane bound enzymes and antioxidant status in streptozotocin-induced diabetic rats was investigated. The streptozotocin-induced diabetic rats were treated with 2-hydroxy-4-methoxy benzo...

journal_title：Indian journal of pharmaceutical sciences

authors： Gayathri M,Kannabiran K

更新日期：2012-09-01 00:00:00

abstract：:Piper claussenianum inflorescences crude methanol extract was tested for hypoglycemic effect in streptozotocin-induced diabetic rats. The blood glucose levels of rats treated with methanol extract were reduced from 318.4±28.1 mg/dl before treatment to 174.2±38.3 mg/dl after 12 days of treatment (P<0.05). Phytochemical...

journal_title：Indian journal of pharmaceutical sciences

authors： Marques AM,Pereira SL,Paiva RA,Cavalcante CV,Sudo SZ,Tinoco LW,Moreira DL,Guimaraes EF,Sudo RT,Kaplan MA,Sudo GZ

更新日期：2015-03-01 00:00:00