Spectrophotometric estimation of bicalutamide in tablets.

abstract：:A simple, sensitive and reproducible method was developed and validated for the simultaneous estimation of diethylcarbamazine and levocetirizine in its tablet formulation by reverse phase high performance liquid chromatography using Waters1515 HPLC with UV detector at the λ(max) of 224 nm, using Princeton Sphere-100 C...

journal_title：Indian journal of pharmaceutical sciences

authors： Reddy JM,Jeyaprakash MR,Madhuri K,Meyyanathan SN,Elango K

更新日期：2011-05-01 00:00:00

abstract：:The objective of this work was to increase the amount of acyclovir in the basal epidermis, site of herpes virus simplex infection, using the solid lipid nanoparticles loaded gel cream as carriers. Solid lipid nanoparticles were prepared by high pressure homogenisation method and incorporated in a semisolid submicron g...

journal_title：Indian journal of pharmaceutical sciences

authors： Gide PS,Gidwani SK,Kothule KU

更新日期：2013-03-01 00:00:00

abstract：:Asymmetric membrane capsules are a type of osmotic drug delivery systems. They are nondisintegrating capsules, which utilize osmotic pressure to drive the drug outwards for controlled delivery. Preceded by systems such as elementary osmotic pump, controlled porosity osmotic pump, single composition osmotic tablet this...

journal_title：Indian journal of pharmaceutical sciences

authors： Sahoo PK,Makar H

更新日期：2013-03-01 00:00:00

abstract：:Two UV Spectrophotometric and one reverse phase high performance liquid chromatography methods have been developed for the simultaneous estimation of amlodipine besilate and olmesartan medoxomil in tablet dosage form. First UV spectrophotometric method was a determination using the simultaneous equation method at 237....

journal_title：Indian journal of pharmaceutical sciences

authors： Wankhede SB,Wadkar SB,Raka KC,Chitlange SS

更新日期：2009-09-01 00:00:00

abstract：:Recent studies have shown that gallic acid and its alkylesters induce apoptosis in different cell lines. Since new compounds with biological activity and less cytotoxicity to normal cells are necessary for cancer therapy, the aim of this study was to evaluate the cytotoxic effect of 1-(3,4,5-trihydroxyphenyl)-dodecylb...

journal_title：Indian journal of pharmaceutical sciences

authors： Maioral MF,Bubniak LD,Marzarotto MA,De Moraes AC,Leal P,Nunes R,Yunes RA,Santos-Silva MC

更新日期：2016-01-01 00:00:00

abstract：:Bacteria have developed multidrug resistance against available antimicrobial agents. Infectious diseases caused by these multidrug-resistant bacteria are major causes of morbidity and mortality in human beings. Synthetic drugs are expensive and inadequate for the treatment of diseases, causing side effects and ineffec...

journal_title：Indian journal of pharmaceutical sciences

authors： Venkatadri B,Arunagirinathan N,Rameshkumar MR,Ramesh L,Dhanasezhian A,Agastian P

更新日期：2015-11-01 00:00:00

abstract：:Ivermectin, chloramphenicol, ampicillin and tetracycline HCl are common drugs in human and veterinary practice. The purpose of this study is to investigate the possible binding interactions between ivermectin and the antibiotics chloramphenicol, ampicillin and tetracycline HCl. Isothermal titration calorimetry was use...

journal_title：Indian journal of pharmaceutical sciences

authors： Kandeel M,Elgazar W,Kitade Y

更新日期：2012-11-01 00:00:00

abstract：:A series of novel isatine-sulphonamide derivatives have been synthesized by combining isatin derivatives with sulphonamides. The structure of the synthesized compounds were elucidated by spectral analysis (IR, NMR and Mass). Investigation of anti-HIV activity was done against HIV-1(IIIB) in MT-4 cells and HIV integras...

journal_title：Indian journal of pharmaceutical sciences

authors： Selvam P,Murugesh N,Chandramohan M,Debyser Z,Witvrouw M

更新日期：2008-11-01 00:00:00

abstract：:A simple, reproducible and efficient reverse phase high performance liquid chromatographic method was developed for simultaneous determination of valsartan and hydrochlorothiazide in tablets. A column having 200 x 4.6 mm i.d. in isocratic mode with mobile phase containing methanol:acetonitrile:water:isopropylalcohol (...

journal_title：Indian journal of pharmaceutical sciences

authors： Tian DF,Tian XL,Tian T,Wang ZY,Mo FK

更新日期：2008-05-01 00:00:00

abstract：:Breast cancer is the foremost common malignancy among the female population around the world. Female breast cancer incidence rates have increased since 1980, slowed in 1990, the rate of increase have leveled off since 2001. In spite of the advances in the early detection, treatment, surgery and radiation support, almo...

journal_title：Indian journal of pharmaceutical sciences

authors： Mohan A,Ponnusankar S

更新日期：2013-05-01 00:00:00

abstract：:Pyrazinamide, a highly specific agent against Mycobacterium tuberculosis is used as first-line drug to treat tuberculosis. The current work aims to formulate polymeric nanoparticles based drug delivery system to sustain the release profile and reduce the dosing frequency of pyrazinamide. Further aim was to target the ...

journal_title：Indian journal of pharmaceutical sciences

authors： Varma JN,Kumar TS,Prasanthi B,Ratna JV

更新日期：2015-05-01 00:00:00

abstract：:Crystal form can be crucial to the performance of a dosage form. This is especially true for compounds that have intrinsic barriers to drug delivery, such as low aqueous solubility, slow dissolution in gastrointestinal media, low permeability and first-pass metabolism. The nature of the physical form and formulation t...

journal_title：Indian journal of pharmaceutical sciences

authors： Yadav AV,Shete AS,Dabke AP,Kulkarni PV,Sakhare SS

更新日期：2009-07-01 00:00:00

abstract：:Fast dissolving tablets of clonazepam were prepared by sublimation method with a view to enhance patient compliance. A 3(2) full factorial design was applied to investigate the combined effect of two formulation variables: amount of croscarmellose sodium and camphor. Croscarmellose sodium (2-8% w/w) was used as superd...

journal_title：Indian journal of pharmaceutical sciences

authors： Shirsand SB,Suresh S,Kusumdevi V,Swamy PV

更新日期：2011-09-01 00:00:00

abstract：:Alpinia officinarum is a rhizome belonging to the family zingeberaeceae. Hydro alcoholic extract by hot and cold maceration and methanol extract by percolation process Qualitative phytochemical analysis of extract of Alpinia officinarum rhizome showed a majority of the compound including tannins, alkaloids, flavonoids...

journal_title：Indian journal of pharmaceutical sciences

authors： Srividya AR,Dhanabal SP,Misra VK,Suja G

更新日期：2010-01-01 00:00:00

abstract：:The results of our previous investigations on extracts of selected marine algae showed that Caulerpa peltata and Padina gymnospora had more promising antiproliferative and antioxidant activities than Gelidiella acerosa and Sargassum wightii. Based on these results, the more active chloroform extract of C. peltata and ...

journal_title：Indian journal of pharmaceutical sciences

authors： Murugan K,Iyer VV

更新日期：2014-11-01 00:00:00

abstract：:The present work describes a simple, precise and accurate HPLC method for estimation of montelukast sodium in bulk and in tablet dosage form. The separation was achieved by using octadecylsilane column (C18) and acetonitrile:1 mM sodium acetate adjusted to pH 6.3 with acetic acid in proportion of 90:10 v/v as mobile p...

journal_title：Indian journal of pharmaceutical sciences

authors： Singh RM,Saini PK,Mathur SC,Singh GN,Lal B

更新日期：2010-03-01 00:00:00

abstract：:Sarpagandha ghanvati is a classical Ayurvedic formulation widely prescribed for anxiety and insomnia. It contains Sarpagandha (roots of Rauwolfia serpentina L. (Benth.) Ex Kurz; Family: Apocyanaceae), Khurasani ajowan (Hyocyamus niger L.; Family: Solanaceae) seeds, Jatamansi (Nardostachys jatamansi DC. Family: Valeria...

journal_title：Indian journal of pharmaceutical sciences

authors： Pundarikakshudu K,Bhatt CJ

更新日期：2015-09-01 00:00:00

abstract：:The formulations consisting of a hydrophilic and hydrophobic material were investigated for effect on drug-release pattern from the matrices. Gum damar and gum copal being water-insoluble were used to study the efficiency of combined matrices to sustain the release of drug. Hydroxypropyl methylcellulose K100M and dicl...

journal_title：Indian journal of pharmaceutical sciences

authors： Fulbandhe VM,Jobanputra CR,Wadher KJ,Umekar MJ,Bhoyar GS

更新日期：2012-05-01 00:00:00

abstract：:Aqueous extract of leaves of Nelumbo nucifera was investigated on acute stress (immobilization stress)-induced biochemical alterations in Swiss mice. The animals were also subjected to acute physical stress (swimming endurance test) and acute chemical stress (writhing test) to gauge the antistress potential of the ext...

journal_title：Indian journal of pharmaceutical sciences

authors： Kulkarni MP,Juvekar AR

更新日期：2008-05-01 00:00:00

abstract：:In the present investigation chitosan has been chemically modified by treating with two different aldehydes like acetaldehyde and propionaldehyde to form Schiff's bases. Schiff's bases of chitosan with acetaldehyde and propionaldehyde were named as polymer A and polymer B, respectively. Fourier Transform Infra Red (FT...

journal_title：Indian journal of pharmaceutical sciences

authors： Wahid A,Sridhar BK,Shivakumar S

更新日期：2008-07-01 00:00:00

abstract：:Wound healing agents support the natural healing process, reduce trauma and likelihood of secondary infections and hasten wound closure. The wound healing activities of water in oil cream of the methanol extract of Hibiscus sabdariffa L. (Malvaceae) was evaluated in rats with superficial skin excision wounds. Antibact...

journal_title：Indian journal of pharmaceutical sciences

authors： Builders PF,Kabele-Toge B,Builders M,Chindo BA,Anwunobi PA,Isimi YC

更新日期：2013-01-01 00:00:00

abstract：:A simultaneous determination of olmesartan medoxomil and hydrochlorothiazide by absorption ratio spectrophotometric method has been developed in combined tablet dosage form. The method is based on measurements of absorbance at isoabsoptive point. The Beer's law obeys in the range of 10-30 mug/ml for both olmesartan me...

journal_title：Indian journal of pharmaceutical sciences

authors： Rote AR,Bari PD

更新日期：2010-01-01 00:00:00

abstract：:Malnutrition is widely prevalent among patients on hemodialysis. Malnutrition can be estimated using a fully quantitative scoring system Subjective Global Assessment-Dialysis Malnutrition Score which is simple, reliable and dynamic. The primary objective of the study was to assess the severity of malnutrition in patie...

journal_title：Indian journal of pharmaceutical sciences

authors： Janardhan V,Soundararajan P,Rani NV,Kannan G,Thennarasu P,Chacko RA,Reddy CU

更新日期：2011-01-01 00:00:00

abstract：:A simple accurate, sensitive and reproducible spectrofluorimetric method was developed for the analysis of duloxetine hydrochloride in pure and pharmaceutical dosage form. Duloxetine hydrochloride showed strong native fluorescence in 0.05 M acetic acid having excitation at 225 nm and emission at 340 nm. Effect of diff...

journal_title：Indian journal of pharmaceutical sciences

authors： Prabu SL,Shahnawaz S,Kumar CD,Shirwaikar A

更新日期：2008-07-01 00:00:00

abstract：:Piper claussenianum inflorescences crude methanol extract was tested for hypoglycemic effect in streptozotocin-induced diabetic rats. The blood glucose levels of rats treated with methanol extract were reduced from 318.4±28.1 mg/dl before treatment to 174.2±38.3 mg/dl after 12 days of treatment (P<0.05). Phytochemical...

journal_title：Indian journal of pharmaceutical sciences

authors： Marques AM,Pereira SL,Paiva RA,Cavalcante CV,Sudo SZ,Tinoco LW,Moreira DL,Guimaraes EF,Sudo RT,Kaplan MA,Sudo GZ

更新日期：2015-03-01 00:00:00

abstract：:It is now known that vitamin D deficiency is a worldwide health problem. In our country, as food fortification is lacking, supplementation with pharmaceutical preparations is the only means of treatment of vitamin D deficiency. We aimed to study the composition and availability of various vitamin D preparations in the...

journal_title：Indian journal of pharmaceutical sciences

authors： Lhamo Y,Chugh PK,Tripathi CD

更新日期：2016-01-01 00:00:00

abstract：:Objective of the present study was to develop and evaluate vaginal films with essential in vitro studies. Films were developed using hydroxypropyl methylcellulose as a polymer and formulations were coded. The developed films were evaluated with Fourier transform infrared spectroscopy, drug content, viscosity, surface ...

journal_title：Indian journal of pharmaceutical sciences

authors： Kumar L,Reddy MS,Shirodkar RK,Pai GK,Krishna VT,Verma R

更新日期：2013-09-01 00:00:00

abstract：:The effect of some physical and nutritional parameters were studied for the optimum production of extracellular enzyme hyaluronidase employing Streptococcus mitis MTCC*2695 by submerged fermentation. The effects of initial pH, incubation temperature and time, inoculum level and age of inoculum were studied. The maximu...

journal_title：Indian journal of pharmaceutical sciences

authors： Sahoo S,Panda PK,Mishra SR,Nayak A,Dash SK,Ellaiah P

更新日期：2008-09-01 00:00:00

abstract：:Various (4-substituted) phenyl-3-β-[(N-benzenesulphonyl/tosyl)-4-(un)substituted anilino]propionylamido-1,3-thiazolidine-4-ones (3a-x) and 1-β-[(N-benzenesulphonyl/tosyl)-4-(un)substituted anilino]-propionylamido-3-chloro-4-(4-substituted)phenyl-azetidin-2-ones (4a-x) have been synthesised by the cyclocondensation of ...

journal_title：Indian journal of pharmaceutical sciences

authors： Desai SR,Laddi UV,Bennur RS,Bennur SC

更新日期：2011-07-01 00:00:00

abstract：:A novel, efficient and simple approach for soy phosphatidylcholine analysis according to its fatty acid composition was studied with reverse-phase high-performance liquid chromatography. The reverse-phase high-performance liquid chromatography analysis was performed isocratically using UV detector and simple mobile ph...

journal_title：Indian journal of pharmaceutical sciences

authors： Jangle RD,Galge RV,Patil VV,Thorat BN

更新日期：2013-05-01 00:00:00