Spectrophotometric estimation of bicalutamide in tablets.

Abstract:

:A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of bicalutamide in bulk and pharmaceutical dosage forms. Bicalutamide shows maximum absorbance at 272 nm with molar absorptivity of 2.3399×10(4) l/mol/cm. Beer's law was obeyed in the concentration range of 1.5-18 μg/ml. The limit of detection and limit of quantification were found to be 0.1 and 0.4 μg/ml, respectively. Results of analysis were validated statistically and by recovery studies.

journal_name

Indian J Pharm Sci

authors

Sancheti PP,Vyas VM,Shah M,Karekar P,Pore YV

doi

10.4103/0250-474X.49131

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

810-2

issue

6

eissn

0250-474X

issn

1998-3743

journal_volume

70

pub_type

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