In vitro Evaluation of Anthelmintic Activity of Nauclea orientalis Leaves.

abstract：:A set of seventy four molecules belonging to the class of thioglitazones were subjected to the QSAR analysis for their antihyperglycemic activity. All the molecules were subjected to energy minimization to get 3D structures, followed by conformational analysis to get the conformation of the molecule associated with th...

journal_title：Indian journal of pharmaceutical sciences

authors： Prashantha Kumar BR,Nanjan MJ

更新日期：2008-09-01 00:00:00

abstract：:This study aims at the isolation of filamentous fungi, extraction of metabolites, and evaluation of the cytotoxic properties on HeLa cells and normal human lymphocytes. We isolated fungi from the soil by serial dilution method. One of the isolates was chosen and identified as Aspergillus ochraceus Wilhelm (Trichocomac...

journal_title：Indian journal of pharmaceutical sciences

authors： Nadumane VK,Venkat P,Pal A,Dharod H,Shukla M,Prashanthi K

更新日期：2013-09-01 00:00:00

abstract：:A simple, rapid, specific and sensitive liquid chromatography tandem mass spectrometric method has been developed and validated for the determination of doxycycline from the human plasma. Doxycycline is extracted from human plasma by solid phase extraction. Demeclocycline was used as an internal standard. Detection wa...

journal_title：Indian journal of pharmaceutical sciences

authors： Krishna AC,Sathiyaraj M,Saravanan RS,Chelladurai R,Vignesh R

更新日期：2012-11-01 00:00:00

abstract：:Bacteria have developed multidrug resistance against available antimicrobial agents. Infectious diseases caused by these multidrug-resistant bacteria are major causes of morbidity and mortality in human beings. Synthetic drugs are expensive and inadequate for the treatment of diseases, causing side effects and ineffec...

journal_title：Indian journal of pharmaceutical sciences

authors： Venkatadri B,Arunagirinathan N,Rameshkumar MR,Ramesh L,Dhanasezhian A,Agastian P

更新日期：2015-11-01 00:00:00

abstract：:Modification of polymers by covalent attachment of thiol bearing pendant groups is reported to impart many beneficial properties to them. Hence in the present study, sodium alginate-cysteine conjugate was synthesized by carbodiimide mediated coupling under varying reaction conditions and the derivatives characterized ...

journal_title：Indian journal of pharmaceutical sciences

authors： Jindal AB,Wasnik MN,Nair HA

更新日期：2010-11-01 00:00:00

abstract：:The formulations consisting of a hydrophilic and hydrophobic material were investigated for effect on drug-release pattern from the matrices. Gum damar and gum copal being water-insoluble were used to study the efficiency of combined matrices to sustain the release of drug. Hydroxypropyl methylcellulose K100M and dicl...

journal_title：Indian journal of pharmaceutical sciences

authors： Fulbandhe VM,Jobanputra CR,Wadher KJ,Umekar MJ,Bhoyar GS

更新日期：2012-05-01 00:00:00

abstract：:A derivative UV spectrophotometric and a reversed phase high-performance liquid chromatographic method for the determination of ciprofibrate in tablets was developed. The first-order derivative UV spectrophotometric method was found to be accurate with 100.57±0.97 recovery and precise with a coefficient of variation o...

journal_title：Indian journal of pharmaceutical sciences

authors： Jain PS,Jivani HN,Khatal RN,Surana SJ

更新日期：2012-03-01 00:00:00

abstract：:This study was designed to evaluate the neuroprotective activity of ethanol extract of Pongamia pinnata stem bark in monosodium glutamate-induced neurotoxicity in rats. Neurotoxicity was induced by intraperitoneal injection of monosodium glutamate 2 g per kg body weight daily for 7 days. Ethanol extract of Pongamia pi...

journal_title：Indian journal of pharmaceutical sciences

authors： Swamy AH,Patel NL,Gadad PC,Koti BC,Patel UM,Thippeswamy AH,Manjula DV

更新日期：2013-11-01 00:00:00

abstract：:A rapid and sensitive reverse phase high performance liquid chromatographic method is depicted for the qualitative and quantitative assay of letrozole in pharmaceutical dosage forms. Letrozole was chromatographed on a reverse phase C18 column with a mobile phase consisting of acetonitrile and phosphate buffer (pH 7.8)...

journal_title：Indian journal of pharmaceutical sciences

authors： Laha TK,Patnaik RK,Sen S

更新日期：2008-05-01 00:00:00

abstract：:Present study aims to prepare and evaluate niacin microspheres. Niacin-ethyl cellulose microspheres were prepared by water-in-oil-in-oil double emulsion solvent diffusion method. Spherical, free flowing microspheres having an entrapment efficiency of 72% were obtained. The effect of polymer-drug ratio, surfactant conc...

journal_title：Indian journal of pharmaceutical sciences

authors： Maravajhala V,Dasari N,Sepuri A,Joginapalli S

更新日期：2009-11-01 00:00:00

abstract：:A stability-indicating reversed-phase liquid chromatographic method has been developed and validated for simultaneous determination of losartan potassium and ramipril. Separations were achieved using a C(18) column with mobile phase consisting of acetonitrile and (0.2% v/v, pH 2.5) aqueous trifluoroacetic acid (45:55,...

journal_title：Indian journal of pharmaceutical sciences

authors： Kollipara S,Bende G,Bansal Y,Saha R

更新日期：2012-05-01 00:00:00

abstract：:A field experiment on the effect of time of harvesting on yield and quality of Melissa officinalis L. was conducted under the agroclimatic conditions of Doon valley, Uttarakhand in order to assess the performance of four harvesting times (H1-120 days, H2-140 days, H3-160 days and H4-180 days after planting). The fresh...

journal_title：Indian journal of pharmaceutical sciences

authors： Singh S,Haider SZ,Chauhan NK,Lohani H,Sah S,Yadav RK

更新日期：2014-09-01 00:00:00

abstract：:In the present investigation chitosan has been chemically modified by treating with two different aldehydes like acetaldehyde and propionaldehyde to form Schiff's bases. Schiff's bases of chitosan with acetaldehyde and propionaldehyde were named as polymer A and polymer B, respectively. Fourier Transform Infra Red (FT...

journal_title：Indian journal of pharmaceutical sciences

authors： Wahid A,Sridhar BK,Shivakumar S

更新日期：2008-07-01 00:00:00

abstract：:Pueraria tuberosa is known for its therapeutic potentials in cardiovascular disorders, but its effect in angiogenesis has not been studied so far. In this study, a computational approach has been applied to elucidate the role of the phytochemicals in inhibition of angiogenesis through modulation of vascular endothelia...

journal_title：Indian journal of pharmaceutical sciences

authors： Asthana S,Agarwal T,Singothu S,Samal A,Banerjee I,Pal K,Pramanik K,Ray SS

更新日期：2015-07-01 00:00:00

abstract：:A novel, simple, sensitive and rapid spectrophotometric method has been developed for simultaneous estimation of esomeprazole and domperidone. The method involved solving simultaneous equations based on measurement of absorbance at two wavelengths, 301 nm and 284 nm, lambda max of esomeprazole and domperidone respecti...

journal_title：Indian journal of pharmaceutical sciences

authors： Prabu SL,Shirwaikar A,Shirwaikar A,Kumar CD,Joseph A,Kumar R

更新日期：2008-01-01 00:00:00

abstract：:Various (4-substituted) phenyl-3-β-[(N-benzenesulphonyl/tosyl)-4-(un)substituted anilino]propionylamido-1,3-thiazolidine-4-ones (3a-x) and 1-β-[(N-benzenesulphonyl/tosyl)-4-(un)substituted anilino]-propionylamido-3-chloro-4-(4-substituted)phenyl-azetidin-2-ones (4a-x) have been synthesised by the cyclocondensation of ...

journal_title：Indian journal of pharmaceutical sciences

authors： Desai SR,Laddi UV,Bennur RS,Bennur SC

更新日期：2011-07-01 00:00:00

abstract：:Fexofenadine is a selective histamine H(1) receptor antagonist, used for relief of the symptoms of allergy. However its aqueous solubility is very poor. Solid inclusion complexes of fexofenadine and β-cyclodextrin were prepared at the molar ratios of 1:1 and 1:2 by kneading, and coprecipitation methods to improve its ...

journal_title：Indian journal of pharmaceutical sciences

authors： Sapkal NP,Kilor VA,Shewale BD,Bhusari KP,Daud AS

更新日期：2010-05-01 00:00:00

abstract：:An in vitro evaluation of the anti-microbial activity of medicated soaps was conducted using ditch-plate and hand washing techniques. Strains of reference microbes namely Candida albicans (ATCC90028), Staphylococcus aureus (ATCC25923), Pseudomonas aureginosa (ATCC27853) and Escherichia coli (ATCC25922) were tested at ...

journal_title：Indian journal of pharmaceutical sciences

authors： Mwambete KD,Lyombe F

更新日期：2011-01-01 00:00:00

abstract：:In the present study petroleum ether and alcoholic extracts of Centratherum anthelminticum (L) Kuntze seed (100 mg and 200 mg/kg p.o.) were evaluated for antiinflammatory activity in acute and subacute models of inflammation. It was found that both petroleum ether and alcoholic extracts showed significant reduction in...

journal_title：Indian journal of pharmaceutical sciences

authors： Ashok P,Koti BC,Thippeswamy AH,Tikare VP,Dabadi P,Viswanathaswamy AH

更新日期：2010-11-01 00:00:00

abstract：:The present study evaluated the in vitro antioxidant potential of different parts of Oroxylum indicum. 2,2-diphelyl 1-picrylhydrazyl (DPPH), nitric oxide, superoxide anion and hydroxyl radical scavenging potential and reductive ability assay of methanol extract of different parts i.e. root, root bark, stem, stem bark,...

journal_title：Indian journal of pharmaceutical sciences

authors： Mishra SL,Sinhamahapatra PK,Nayak A,Das R,Sannigrahi S

更新日期：2010-03-01 00:00:00

abstract：:The petroleum ether leaf extract of Ficus krishnae has been evaluated for the management of diabetes in alloxan induced diabetic rats. Phytochemical screening of the leaf extract for various chemical compounds has also been carried out. Leaf extract was administered continuously for 21 days orally at a dose of 200 mg/...

journal_title：Indian journal of pharmaceutical sciences

authors： Sidhu MC,Sharma T

更新日期：2014-07-01 00:00:00

abstract：:Ivermectin, chloramphenicol, ampicillin and tetracycline HCl are common drugs in human and veterinary practice. The purpose of this study is to investigate the possible binding interactions between ivermectin and the antibiotics chloramphenicol, ampicillin and tetracycline HCl. Isothermal titration calorimetry was use...

journal_title：Indian journal of pharmaceutical sciences

authors： Kandeel M,Elgazar W,Kitade Y

更新日期：2012-11-01 00:00:00

abstract：:A few flavanones were synthesised by cyclisation of corresponding 3-(heteroaryl)-1(2-hydroxyphenyl) prop-2-en-1-one with sodium acetate in alcohol-water and evaluated for activity. Synthesised compounds were assayed for their in vitro anticancer activity against three human cancer cell lines, mammary adenocarcinoma (M...

journal_title：Indian journal of pharmaceutical sciences

authors： Murti Y,Mishra P

更新日期：2014-03-01 00:00:00

abstract：:The antibacterial activity of leaf extract of mangroves, namely, Rhizophora mucronata, Sonneratia alba and Exoecaria agallocha from Chorao island, Goa was investigated against human bacterial pathogens Staphylococcus aureus, Streptococcus sp., Salmonella typhi, Proteus vulgaris and Proteus mirabilis. As compared to aq...

journal_title：Indian journal of pharmaceutical sciences

authors： Sahoo G,Mulla NS,Ansari ZA,Mohandass C

更新日期：2012-07-01 00:00:00

abstract：:Manjisthadi churna has been traditionally used in the Ayurvedic system of medicine and by traditional medical practices of India to treat hyperlipidemia. A rapid, simple and accurate method with high performance thin layer chromatography has been developed to standardised Manjisthadi churna using rubiadin, sennoside a...

journal_title：Indian journal of pharmaceutical sciences

authors： Patel VR,Patel RK

更新日期：2013-01-01 00:00:00

abstract：:The present study depicts the development of a validated RP-HPLC method for the determination of the pamabrom in presence of degradation products or other pharmaceutical excipients. Stress study was performed on pamabrom and it was found that it degrade sufficiently in acidic, alkali and oxidative condition but less d...

journal_title：Indian journal of pharmaceutical sciences

authors： Shah U,Kavad M,Raval M

更新日期：2014-05-01 00:00:00

abstract：:The objective of this investigation was to prepare the shellac wax matrix tablets by fusion and molding technique incorporated with Lutrol in different ratios to modify the hydrophobicity of matrix tablet. The matrix tablets with single drug were loaded either with propranolol hydrochloride or hydrochlorothiazide as h...

journal_title：Indian journal of pharmaceutical sciences

authors： Phaechamud T,Choncheewa C

更新日期：2015-01-01 00:00:00

abstract：:Present study reports the development and validation of a simultaneous estimation of metformin and gliclazide in human plasma using supercritical fluid chromatography followed by tandem mass spectrometry. Acetonitrile:water (80:20) mixture was used as a mobile phase along with liquid CO(2) in supercritical fluid chrom...

journal_title：Indian journal of pharmaceutical sciences

authors： Agrawal YK,Gogoi PJ,Manna K,Bhatt HG,Jain VK

更新日期：2010-01-01 00:00:00

abstract：:Two UV Spectrophotometric and one reverse phase high performance liquid chromatography methods have been developed for the simultaneous estimation of amlodipine besilate and olmesartan medoxomil in tablet dosage form. First UV spectrophotometric method was a determination using the simultaneous equation method at 237....

journal_title：Indian journal of pharmaceutical sciences

authors： Wankhede SB,Wadkar SB,Raka KC,Chitlange SS

更新日期：2009-09-01 00:00:00

abstract：:Supercritical fluid extract of leaves of Vitex negundo was tested for its antimicrobial potential and was compared with that of ethanol extract, ether extract and hydrodistilled oil of leaves. The chemical constituents of extracts were studied by chromatographic techniques. Extracts were evaluated for antimicrobial po...

journal_title：Indian journal of pharmaceutical sciences

authors： Nagarsekar KS,Nagarsenker MS,Kulkarni SR

更新日期：2010-09-01 00:00:00