Optimization of Physical and Nutritional Parameters for Hyaluronidase Production by Streptococcus mitis.

abstract：:Present study aims to prepare and evaluate niacin microspheres. Niacin-ethyl cellulose microspheres were prepared by water-in-oil-in-oil double emulsion solvent diffusion method. Spherical, free flowing microspheres having an entrapment efficiency of 72% were obtained. The effect of polymer-drug ratio, surfactant conc...

journal_title：Indian journal of pharmaceutical sciences

authors： Maravajhala V,Dasari N,Sepuri A,Joginapalli S

更新日期：2009-11-01 00:00:00

abstract：:In this paper we report the synthesis of a new family of 4-alkyl isocoumarin derivatives having bromo carbonyl and amino carbonyl group at 3(rd) position of the heterocyclic ring. Synthesis, spectral analysis and bioactivity of new isocoumarin derivatives are discussed in this paper. Some of the synthesized compounds ...

journal_title：Indian journal of pharmaceutical sciences

authors： Yadav P,Purohit NV

更新日期：2011-03-01 00:00:00

abstract：:The rising problem of resistance to most commonly used antimalarials remains a major challenge in the control of malaria suggesting the need for new antimalarial agents. This work explores the antiplasmodial potential of ethanol extract of Russelia equisetiformis in chloroquine Plasmodium berghei infected mice. Swiss ...

journal_title：Indian journal of pharmaceutical sciences

authors： Ojurongbe O,Ojo JA,Adefokun DI,Abiodun OO,Odewale G,Awe EO

更新日期：2015-07-01 00:00:00

abstract：:A simple, rapid, specific and sensitive liquid chromatography tandem mass spectrometric method has been developed and validated for the determination of doxycycline from the human plasma. Doxycycline is extracted from human plasma by solid phase extraction. Demeclocycline was used as an internal standard. Detection wa...

journal_title：Indian journal of pharmaceutical sciences

authors： Krishna AC,Sathiyaraj M,Saravanan RS,Chelladurai R,Vignesh R

更新日期：2012-11-01 00:00:00

abstract：:Supercritical fluid extract of leaves of Vitex negundo was tested for its antimicrobial potential and was compared with that of ethanol extract, ether extract and hydrodistilled oil of leaves. The chemical constituents of extracts were studied by chromatographic techniques. Extracts were evaluated for antimicrobial po...

journal_title：Indian journal of pharmaceutical sciences

authors： Nagarsekar KS,Nagarsenker MS,Kulkarni SR

更新日期：2010-09-01 00:00:00

abstract：:Asymmetric membrane capsules are a type of osmotic drug delivery systems. They are nondisintegrating capsules, which utilize osmotic pressure to drive the drug outwards for controlled delivery. Preceded by systems such as elementary osmotic pump, controlled porosity osmotic pump, single composition osmotic tablet this...

journal_title：Indian journal of pharmaceutical sciences

authors： Sahoo PK,Makar H

更新日期：2013-03-01 00:00:00

abstract：:Duloxetine hydrochloride is a potent dual reuptake inhibitor of serotonin and norepinephrine used to treat major depressive disorders. The present work describes a simple, precise and accurate HPTLC method for its estimation as bulk and in tablet dosage form. The chromatographic separation was carried out on precoated...

journal_title：Indian journal of pharmaceutical sciences

authors： Dhaneshwar SS,Deshpande P,Patil M,Vadnerkar G,Dhaneshwar SR

更新日期：2008-03-01 00:00:00

abstract：:Floating matrix tablets of domperidone were developed to prolong gastric residence time and thereby increased drug bioavailability. Domperidone was chosen as a model drug because it is poorly absorbed from the lower gastrointestinal tract. The tablets were prepared by wet granulation technique, using polymers such as ...

journal_title：Indian journal of pharmaceutical sciences

authors： Prajapati ST,Patel LD,Patel DM

更新日期：2009-01-01 00:00:00

abstract：:Two UV Spectrophotometric and one reverse phase high performance liquid chromatography methods have been developed for the simultaneous estimation of amlodipine besilate and olmesartan medoxomil in tablet dosage form. First UV spectrophotometric method was a determination using the simultaneous equation method at 237....

journal_title：Indian journal of pharmaceutical sciences

authors： Wankhede SB,Wadkar SB,Raka KC,Chitlange SS

更新日期：2009-09-01 00:00:00

abstract：:Etoposide is a semisynthetic compound, widely used in treatment of non small cell lung cancer. However, frequent dosing and adverse effects remain a major concern in the use of etoposide. Liposomal systems for pulmonary drug delivery have been particularly attractive because of their compatibility with lung surfactant...

journal_title：Indian journal of pharmaceutical sciences

authors： Parmar JJ,Singh DJ,Lohade AA,Hegde DD,Soni PS,Samad A,Menon MD

更新日期：2011-11-01 00:00:00

abstract：:An in vitro evaluation of the anti-microbial activity of medicated soaps was conducted using ditch-plate and hand washing techniques. Strains of reference microbes namely Candida albicans (ATCC90028), Staphylococcus aureus (ATCC25923), Pseudomonas aureginosa (ATCC27853) and Escherichia coli (ATCC25922) were tested at ...

journal_title：Indian journal of pharmaceutical sciences

authors： Mwambete KD,Lyombe F

更新日期：2011-01-01 00:00:00

abstract：:Fast dissolving tablets of clonazepam were prepared by sublimation method with a view to enhance patient compliance. A 3(2) full factorial design was applied to investigate the combined effect of two formulation variables: amount of croscarmellose sodium and camphor. Croscarmellose sodium (2-8% w/w) was used as superd...

journal_title：Indian journal of pharmaceutical sciences

authors： Shirsand SB,Suresh S,Kusumdevi V,Swamy PV

更新日期：2011-09-01 00:00:00

abstract：:Manjisthadi churna has been traditionally used in the Ayurvedic system of medicine and by traditional medical practices of India to treat hyperlipidemia. A rapid, simple and accurate method with high performance thin layer chromatography has been developed to standardised Manjisthadi churna using rubiadin, sennoside a...

journal_title：Indian journal of pharmaceutical sciences

authors： Patel VR,Patel RK

更新日期：2013-01-01 00:00:00

abstract：:In the present investigation chitosan has been chemically modified by treating with two different aldehydes like acetaldehyde and propionaldehyde to form Schiff's bases. Schiff's bases of chitosan with acetaldehyde and propionaldehyde were named as polymer A and polymer B, respectively. Fourier Transform Infra Red (FT...

journal_title：Indian journal of pharmaceutical sciences

authors： Wahid A,Sridhar BK,Shivakumar S

更新日期：2008-07-01 00:00:00

abstract：:Malnutrition is widely prevalent among patients on hemodialysis. Malnutrition can be estimated using a fully quantitative scoring system Subjective Global Assessment-Dialysis Malnutrition Score which is simple, reliable and dynamic. The primary objective of the study was to assess the severity of malnutrition in patie...

journal_title：Indian journal of pharmaceutical sciences

authors： Janardhan V,Soundararajan P,Rani NV,Kannan G,Thennarasu P,Chacko RA,Reddy CU

更新日期：2011-01-01 00:00:00

abstract：:A field experiment on the effect of time of harvesting on yield and quality of Melissa officinalis L. was conducted under the agroclimatic conditions of Doon valley, Uttarakhand in order to assess the performance of four harvesting times (H1-120 days, H2-140 days, H3-160 days and H4-180 days after planting). The fresh...

journal_title：Indian journal of pharmaceutical sciences

authors： Singh S,Haider SZ,Chauhan NK,Lohani H,Sah S,Yadav RK

更新日期：2014-09-01 00:00:00

abstract：:A simple and sensitive spectrofluorimetric method has been developed for the estimation of brimonidine tartrate in pure and eye drops. Linearity was obeyed in the range of 0.2-3.0 ΅g/ml in dimethyl formamide as solvent at an emission wavelength (λem) of 530 nm after excitation wavelength (λex) of 389 nm with good corr...

journal_title：Indian journal of pharmaceutical sciences

authors： Sunitha G,Bhagirath R,Alapati VR,Ramakrishna K,Subrahmanyam CV,Anumolu PD

更新日期：2013-11-01 00:00:00

abstract：:The objective of this investigation was to prepare the shellac wax matrix tablets by fusion and molding technique incorporated with Lutrol in different ratios to modify the hydrophobicity of matrix tablet. The matrix tablets with single drug were loaded either with propranolol hydrochloride or hydrochlorothiazide as h...

journal_title：Indian journal of pharmaceutical sciences

authors： Phaechamud T,Choncheewa C

更新日期：2015-01-01 00:00:00

abstract：:A series of novel 2,3-disubstitutedquinazolin-4(3H)-ones have been synthesized by condensation of 2-substituted benzo[1,3]oxazine-4-ones and anthranilic acid. Synthesized compounds were evaluated for in vitro antiviral activity against HIV, HSV and vaccinia viruses. 5-Bromo-2-(6-bromo-4-oxo-2-phenyl-4H-quinazolin-3-yl...

journal_title：Indian journal of pharmaceutical sciences

authors： Selvam P,Murugesh N,Chandramohan M,Pannecouque C,DE Clercq E

更新日期：2010-11-01 00:00:00

abstract：:A novel, efficient and simple approach for soy phosphatidylcholine analysis according to its fatty acid composition was studied with reverse-phase high-performance liquid chromatography. The reverse-phase high-performance liquid chromatography analysis was performed isocratically using UV detector and simple mobile ph...

journal_title：Indian journal of pharmaceutical sciences

authors： Jangle RD,Galge RV,Patil VV,Thorat BN

更新日期：2013-05-01 00:00:00

abstract：:Modification of polymers by covalent attachment of thiol bearing pendant groups is reported to impart many beneficial properties to them. Hence in the present study, sodium alginate-cysteine conjugate was synthesized by carbodiimide mediated coupling under varying reaction conditions and the derivatives characterized ...

journal_title：Indian journal of pharmaceutical sciences

authors： Jindal AB,Wasnik MN,Nair HA

更新日期：2010-11-01 00:00:00

abstract：:A novel, simple, sensitive and rapid spectrophotometric method has been developed for simultaneous estimation of esomeprazole and domperidone. The method involved solving simultaneous equations based on measurement of absorbance at two wavelengths, 301 nm and 284 nm, lambda max of esomeprazole and domperidone respecti...

journal_title：Indian journal of pharmaceutical sciences

authors： Prabu SL,Shirwaikar A,Shirwaikar A,Kumar CD,Joseph A,Kumar R

更新日期：2008-01-01 00:00:00

abstract：:A series of novel isatine-sulphonamide derivatives have been synthesized by combining isatin derivatives with sulphonamides. The structure of the synthesized compounds were elucidated by spectral analysis (IR, NMR and Mass). Investigation of anti-HIV activity was done against HIV-1(IIIB) in MT-4 cells and HIV integras...

journal_title：Indian journal of pharmaceutical sciences

authors： Selvam P,Murugesh N,Chandramohan M,Debyser Z,Witvrouw M

更新日期：2008-11-01 00:00:00

abstract：:The present study evaluated the in vitro antioxidant potential of different parts of Oroxylum indicum. 2,2-diphelyl 1-picrylhydrazyl (DPPH), nitric oxide, superoxide anion and hydroxyl radical scavenging potential and reductive ability assay of methanol extract of different parts i.e. root, root bark, stem, stem bark,...

journal_title：Indian journal of pharmaceutical sciences

authors： Mishra SL,Sinhamahapatra PK,Nayak A,Das R,Sannigrahi S

更新日期：2010-03-01 00:00:00

abstract：:A high-performance liquid chromatographic method for the estimation of berberine in the stem of Tinospora cordifolia (Willd.) Miers. ex Hook.f. and Thoms. and Tinospora sinensis (Lour.) Merrill is described. The dried stems of T. cordifolia and T. sinensis were defatted with petroleum ether (60-80 degrees ). The marc ...

journal_title：Indian journal of pharmaceutical sciences

authors： Srinivasan GV,Unnikrishnan KP,Rema Shree AB,Balachandran I

更新日期：2008-01-01 00:00:00

abstract：:The present study depicts the development of a validated RP-HPLC method for the determination of the pamabrom in presence of degradation products or other pharmaceutical excipients. Stress study was performed on pamabrom and it was found that it degrade sufficiently in acidic, alkali and oxidative condition but less d...

journal_title：Indian journal of pharmaceutical sciences

authors： Shah U,Kavad M,Raval M

更新日期：2014-05-01 00:00:00

abstract：:The aim of the present study was the determination of formulation factors and the in vitro evaluation of an extended release dosage form of a freely soluble weakly basic drug (alfuzosin hydrochloride). Binary mixer of one hydrophilic polymer (hydroxypropylmethylcellulose) and one directly compressible Eudragit (RS PO)...

journal_title：Indian journal of pharmaceutical sciences

authors： Roni MA,Kibria G,Jalil R

更新日期：2009-05-01 00:00:00

abstract：:Mitochondrial sodium calcium exchange inhibitors are novel agents in the treatment of type-II diabetes due to their glucose dependent efficacy. While the compounds of this class are expected to correct hyperglycemia, they do not lower basal blood glucose level, thus avoiding the serious consequences of hypoglycemia. T...

journal_title：Indian journal of pharmaceutical sciences

authors： Dasoondi AS,Singh V,Voleti SR,Tiwari M

更新日期：2008-03-01 00:00:00

abstract：:In the current research work an attempt was made to develop "Melt in mouth pellets" (Meltlets(®)) containing 40% herbal extract of soy isoflavones that served to provide antioxidants activity in menopausal women. The process of extrusion-spheronization was optimized for extruder speed, extruder screen size, spheroniza...

journal_title：Indian journal of pharmaceutical sciences

authors： Deshmukh K,Amin P

更新日期：2013-07-01 00:00:00

abstract：:The results of our previous investigations on extracts of selected marine algae showed that Caulerpa peltata and Padina gymnospora had more promising antiproliferative and antioxidant activities than Gelidiella acerosa and Sargassum wightii. Based on these results, the more active chloroform extract of C. peltata and ...

journal_title：Indian journal of pharmaceutical sciences

authors： Murugan K,Iyer VV

更新日期：2014-11-01 00:00:00