Spectrophotometric method for simultaneous estimation of escitalopram oxalate and clonazepam in tablet dosage form.

abstract：:Duloxetine hydrochloride is a potent dual reuptake inhibitor of serotonin and norepinephrine used to treat major depressive disorders. The present work describes a simple, precise and accurate HPTLC method for its estimation as bulk and in tablet dosage form. The chromatographic separation was carried out on precoated...

journal_title：Indian journal of pharmaceutical sciences

authors： Dhaneshwar SS,Deshpande P,Patil M,Vadnerkar G,Dhaneshwar SR

更新日期：2008-03-01 00:00:00

abstract：:Alpinia officinarum is a rhizome belonging to the family zingeberaeceae. Hydro alcoholic extract by hot and cold maceration and methanol extract by percolation process Qualitative phytochemical analysis of extract of Alpinia officinarum rhizome showed a majority of the compound including tannins, alkaloids, flavonoids...

journal_title：Indian journal of pharmaceutical sciences

authors： Srividya AR,Dhanabal SP,Misra VK,Suja G

更新日期：2010-01-01 00:00:00

abstract：:Modification of polymers by covalent attachment of thiol bearing pendant groups is reported to impart many beneficial properties to them. Hence in the present study, sodium alginate-cysteine conjugate was synthesized by carbodiimide mediated coupling under varying reaction conditions and the derivatives characterized ...

journal_title：Indian journal of pharmaceutical sciences

authors： Jindal AB,Wasnik MN,Nair HA

更新日期：2010-11-01 00:00:00

abstract：:Manjisthadi churna has been traditionally used in the Ayurvedic system of medicine and by traditional medical practices of India to treat hyperlipidemia. A rapid, simple and accurate method with high performance thin layer chromatography has been developed to standardised Manjisthadi churna using rubiadin, sennoside a...

journal_title：Indian journal of pharmaceutical sciences

authors： Patel VR,Patel RK

更新日期：2013-01-01 00:00:00

abstract：:A derivative UV spectrophotometric and a reversed phase high-performance liquid chromatographic method for the determination of ciprofibrate in tablets was developed. The first-order derivative UV spectrophotometric method was found to be accurate with 100.57±0.97 recovery and precise with a coefficient of variation o...

journal_title：Indian journal of pharmaceutical sciences

authors： Jain PS,Jivani HN,Khatal RN,Surana SJ

更新日期：2012-03-01 00:00:00

abstract：:A gradient reversed phase HPLC method was developed and validated for analysis of betamethasone dipropionate, its related substances and degradation products, using Altima C(18) column (250×4.6 mm, 5 μm) with a flow rate of 1.0 ml/min and detection wavelength of 240 nm. The mobile phase A is a mixture of water, tetrah...

journal_title：Indian journal of pharmaceutical sciences

authors： Vairale AS,Sivaswaroop P,Bandana S

更新日期：2012-03-01 00:00:00

abstract：:The formulations consisting of a hydrophilic and hydrophobic material were investigated for effect on drug-release pattern from the matrices. Gum damar and gum copal being water-insoluble were used to study the efficiency of combined matrices to sustain the release of drug. Hydroxypropyl methylcellulose K100M and dicl...

journal_title：Indian journal of pharmaceutical sciences

authors： Fulbandhe VM,Jobanputra CR,Wadher KJ,Umekar MJ,Bhoyar GS

更新日期：2012-05-01 00:00:00

abstract：:A high-performance liquid chromatographic method for the estimation of berberine in the stem of Tinospora cordifolia (Willd.) Miers. ex Hook.f. and Thoms. and Tinospora sinensis (Lour.) Merrill is described. The dried stems of T. cordifolia and T. sinensis were defatted with petroleum ether (60-80 degrees ). The marc ...

journal_title：Indian journal of pharmaceutical sciences

authors： Srinivasan GV,Unnikrishnan KP,Rema Shree AB,Balachandran I

更新日期：2008-01-01 00:00:00

abstract：:A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of bicalutamide in bulk and pharmaceutical dosage forms. Bicalutamide shows maximum absorbance at 272 nm with molar absorptivity of 2.3399×10(4) l/mol/cm. Beer's law was obeyed in the concentration range of...

journal_title：Indian journal of pharmaceutical sciences

authors： Sancheti PP,Vyas VM,Shah M,Karekar P,Pore YV

更新日期：2008-11-01 00:00:00

abstract：:A series of novel isatine-sulphonamide derivatives have been synthesized by combining isatin derivatives with sulphonamides. The structure of the synthesized compounds were elucidated by spectral analysis (IR, NMR and Mass). Investigation of anti-HIV activity was done against HIV-1(IIIB) in MT-4 cells and HIV integras...

journal_title：Indian journal of pharmaceutical sciences

authors： Selvam P,Murugesh N,Chandramohan M,Debyser Z,Witvrouw M

更新日期：2008-11-01 00:00:00

abstract：:Ethanol extract of leaves of Clerodendron phlomoidis L. subjected to preliminary qualitative phytochemical investigations showed the presence of alkaloids, phytosterols, glycosides, saponins, phenolic compounds, proteins and flavonoids. The extract was screened for hypoglycemic activity in alloxan-induced diabetic rat...

journal_title：Indian journal of pharmaceutical sciences

authors： Dhanabal SP,Mohan Marugaraja MK,Suresh B

更新日期：2008-11-01 00:00:00

abstract：:A series of novel 2,3-disubstitutedquinazolin-4(3H)-ones have been synthesized by condensation of 2-substituted benzo[1,3]oxazine-4-ones and anthranilic acid. Synthesized compounds were evaluated for in vitro antiviral activity against HIV, HSV and vaccinia viruses. 5-Bromo-2-(6-bromo-4-oxo-2-phenyl-4H-quinazolin-3-yl...

journal_title：Indian journal of pharmaceutical sciences

authors： Selvam P,Murugesh N,Chandramohan M,Pannecouque C,DE Clercq E

更新日期：2010-11-01 00:00:00

abstract：:Objective of the present study was to develop and evaluate vaginal films with essential in vitro studies. Films were developed using hydroxypropyl methylcellulose as a polymer and formulations were coded. The developed films were evaluated with Fourier transform infrared spectroscopy, drug content, viscosity, surface ...

journal_title：Indian journal of pharmaceutical sciences

authors： Kumar L,Reddy MS,Shirodkar RK,Pai GK,Krishna VT,Verma R

更新日期：2013-09-01 00:00:00

abstract：:Piper claussenianum inflorescences crude methanol extract was tested for hypoglycemic effect in streptozotocin-induced diabetic rats. The blood glucose levels of rats treated with methanol extract were reduced from 318.4±28.1 mg/dl before treatment to 174.2±38.3 mg/dl after 12 days of treatment (P<0.05). Phytochemical...

journal_title：Indian journal of pharmaceutical sciences

authors： Marques AM,Pereira SL,Paiva RA,Cavalcante CV,Sudo SZ,Tinoco LW,Moreira DL,Guimaraes EF,Sudo RT,Kaplan MA,Sudo GZ

更新日期：2015-03-01 00:00:00

abstract：:A simple, reproducible and efficient reverse phase high performance liquid chromatographic method was developed for simultaneous determination of valsartan and hydrochlorothiazide in tablets. A column having 200 x 4.6 mm i.d. in isocratic mode with mobile phase containing methanol:acetonitrile:water:isopropylalcohol (...

journal_title：Indian journal of pharmaceutical sciences

authors： Tian DF,Tian XL,Tian T,Wang ZY,Mo FK

更新日期：2008-05-01 00:00:00

abstract：:The rising problem of resistance to most commonly used antimalarials remains a major challenge in the control of malaria suggesting the need for new antimalarial agents. This work explores the antiplasmodial potential of ethanol extract of Russelia equisetiformis in chloroquine Plasmodium berghei infected mice. Swiss ...

journal_title：Indian journal of pharmaceutical sciences

authors： Ojurongbe O,Ojo JA,Adefokun DI,Abiodun OO,Odewale G,Awe EO

更新日期：2015-07-01 00:00:00

abstract：:Recent studies have shown that gallic acid and its alkylesters induce apoptosis in different cell lines. Since new compounds with biological activity and less cytotoxicity to normal cells are necessary for cancer therapy, the aim of this study was to evaluate the cytotoxic effect of 1-(3,4,5-trihydroxyphenyl)-dodecylb...

journal_title：Indian journal of pharmaceutical sciences

authors： Maioral MF,Bubniak LD,Marzarotto MA,De Moraes AC,Leal P,Nunes R,Yunes RA,Santos-Silva MC

更新日期：2016-01-01 00:00:00

abstract：:A mucoadhesive drug delivery system for systemic delivery of nitrendipine, a calcium channel blocker through buccal route was formulated. Mucoadhesive polymers like hydroxypropylmethylcellulose K-100, hydroxypropylcellulose, sodium carboxymethylcellulose, sodium alginate, polyvinyl alcohol, polyvinyl pyrrolidone K-30 ...

journal_title：Indian journal of pharmaceutical sciences

authors： Nappinnai M,Chandanbala R,Balaijirajan R

更新日期：2008-09-01 00:00:00

abstract：:Gastroretentive bimodal drug delivery systems of lamotrigine were developed using immediate release and extended release segments incorporated in a hydroxypropyl methylcellulose capsule and in vitro and in vivo evaluations were conducted. In vivo radiographic studies were carried out for the optimized formulation in h...

journal_title：Indian journal of pharmaceutical sciences

authors： Poonuru RR,Gonugunta CS

更新日期：2014-11-01 00:00:00

abstract：:A simple, rapid, specific and sensitive liquid chromatography tandem mass spectrometric method has been developed and validated for the determination of doxycycline from the human plasma. Doxycycline is extracted from human plasma by solid phase extraction. Demeclocycline was used as an internal standard. Detection wa...

journal_title：Indian journal of pharmaceutical sciences

authors： Krishna AC,Sathiyaraj M,Saravanan RS,Chelladurai R,Vignesh R

更新日期：2012-11-01 00:00:00

abstract：:A stability-indicating reversed-phase liquid chromatographic method has been developed and validated for simultaneous determination of losartan potassium and ramipril. Separations were achieved using a C(18) column with mobile phase consisting of acetonitrile and (0.2% v/v, pH 2.5) aqueous trifluoroacetic acid (45:55,...

journal_title：Indian journal of pharmaceutical sciences

authors： Kollipara S,Bende G,Bansal Y,Saha R

更新日期：2012-05-01 00:00:00

abstract：:The effectiveness of liposome-mediated gene transfer methods hinges, in part, on the nature of the interaction between the DNA cargo and the liposomes. Here we have examined the effect of quaternization of the cytofectin cationic head group on this interaction and the effect of concentration of the biocompatible, prot...

journal_title：Indian journal of pharmaceutical sciences

authors： Daniels A,Noor-Mahomed N,Singh M,Ariatti M

更新日期：2011-07-01 00:00:00

abstract：:A few flavanones were synthesised by cyclisation of corresponding 3-(heteroaryl)-1(2-hydroxyphenyl) prop-2-en-1-one with sodium acetate in alcohol-water and evaluated for activity. Synthesised compounds were assayed for their in vitro anticancer activity against three human cancer cell lines, mammary adenocarcinoma (M...

journal_title：Indian journal of pharmaceutical sciences

authors： Murti Y,Mishra P

更新日期：2014-03-01 00:00:00

abstract：:In the present study, 2,5-disubstituted-1,3,4-oxadiazoles (3a-o) have been synthesized by the condensation of 4-methoxybenzohydrazide (1) with different aromatic acids (2a-o) in presence of phosphoryl chloride. The structural assignment of this compound (3a-o) has been made on the basis of elemental analysis, UV, IR, ...

journal_title：Indian journal of pharmaceutical sciences

authors： Nagalakshmi G

更新日期：2008-01-01 00:00:00

abstract：:Ethanol extract of Passiflora edulis Sims was analyzed for its antioxidant (1,1-diphenyl-2-picryl hydrazyl radical reducing power methods) and phytochemical analysis. The extract was found effective against the antioxidant test models exhibiting an IC(50) value of 875+/-87.83 mug/ml and showed strong potential antioxi...

journal_title：Indian journal of pharmaceutical sciences

authors： Sunitha M,Devaki K

更新日期：2009-05-01 00:00:00

abstract：:A novel, efficient and simple approach for soy phosphatidylcholine analysis according to its fatty acid composition was studied with reverse-phase high-performance liquid chromatography. The reverse-phase high-performance liquid chromatography analysis was performed isocratically using UV detector and simple mobile ph...

journal_title：Indian journal of pharmaceutical sciences

authors： Jangle RD,Galge RV,Patil VV,Thorat BN

更新日期：2013-05-01 00:00:00

abstract：:A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for estimation of ropinirole hydrochloride in bulk and tablet dosage forms. Ropinirole hydrochloride shows maximum absorbance at 250 nm with molar absorptivity of 8.703x10(3) l/mol.cm. Beer's law was obeyed in the concentrati...

journal_title：Indian journal of pharmaceutical sciences

authors： Shete Y,Pimpodkar N,Nalawade RS,Pore YV,Kuchekar BS

更新日期：2009-01-01 00:00:00

abstract：:The objective of this study was to prepare and characterise nevirapine nanosuspensions so as to improve the dissolution rate of nevirapine. Nevirapine is a nonnucleoside reverse transcriptase inhibitor of immunodeficiency virus type-1 and it is poorly water-soluble antiretroviral drug. The low solubility of nevirapine...

journal_title：Indian journal of pharmaceutical sciences

authors： Raju A,Reddy AJ,Satheesh J,Jithan AV

更新日期：2014-01-01 00:00:00

abstract：:A reverse phase high performance liquid chromatographic method was developed for the simultaneous estimation of atorvastatin calcium and fenofibrate in tablet formulation. The separation was achieved by Luna C18 column and methanol:acetate buffer pH 3.7 (82:18 v/v) as mobile phase, at a flow rate of 1.5 ml/min. Detect...

journal_title：Indian journal of pharmaceutical sciences

authors： Jain N,Raghuwanshi R,Jain D

更新日期：2008-03-01 00:00:00

abstract：:A simultaneous determination of olmesartan medoxomil and hydrochlorothiazide by absorption ratio spectrophotometric method has been developed in combined tablet dosage form. The method is based on measurements of absorbance at isoabsoptive point. The Beer's law obeys in the range of 10-30 mug/ml for both olmesartan me...

journal_title：Indian journal of pharmaceutical sciences

authors： Rote AR,Bari PD

更新日期：2010-01-01 00:00:00