1-Bromopropane-induced apoptosis in OVCAR-3 cells via oxidative stress and inactivation of Nrf2.

abstract：:The aim of this study was to analyze the biochemical alterations in the gills of Venus verrucosa under exposure for 6 days to three doses of lambda-cyhalothrin (λ-cyh) (100, 250, and 500 µg L-1). Malondialdehyde, lipid hydroperoxide, and hydrogen peroxide levels in the gills of treated groups increased. λ-Cyh exposure...

journal_title：Toxicology and industrial health

authors： Fouzai C,Trabelsi W,Rabeh I,Bejaoui S,Telahigue K,El Cafsi M,Soudani N

更新日期：2020-11-01 00:00:00

abstract：:Peracetic acid (PAA) is a corrosive chemical with a pungent odor, which is extensively used in occupational settings and causes various health hazards in exposed workers. Currently, there is no US government agency recommended method that could be applied universally for the sampling and analysis of PAA. Legacy method...

journal_title：Toxicology and industrial health

authors： Nordling J,Kinsky OR,Osorio M,Pechacek N

更新日期：2017-12-01 00:00:00

abstract：:It has been found that exposure to manganese (Mn) could induce reproductive dysfunction, but its occupational risk in male workers is unclear. This study aims to assess the association of occupational Mn exposure with reproductive hormones and semen quality in a cross-sectional study. Urinary Mn, semen quality, and re...

journal_title：Toxicology and industrial health

authors： Yang H,Wang J,Yang X,Wu F,Qi Z,Xu B,Liu W,Deng Y

更新日期：2019-01-01 00:00:00

abstract：:Trivalent chromium (Cr) is an environmental contaminant, which is extensively used in tanning industries throughout the world and causes various forms of health hazards in tannery workers. Therefore, a cross-sectional study design was used to evaluate the DNA damage and oxidative stress condition in tannery workers ex...

journal_title：Toxicology and industrial health

authors： Ambreen K,Khan FH,Bhadauria S,Kumar S

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the chemopreventive potential of organoselenium compounds (Se I and Se II) in the well-established rat model treated with 7,12-dimethylbenz[a]anthracene (DMBA), by monitoring the extent of tyrosine hydroxylase (TH) activity, adrenomedullin (ADM) level and total RNA level ...

journal_title：Toxicology and industrial health

authors： Talas ZS,Ozdemir I,Ates B,Gok Y,Yilmaz I

更新日期：2013-04-01 00:00:00

abstract：:The objective is to present historical asbestos airborne concentrations associated with activities involving presumably asbestos-containing materials in steel mills. A total of 138 historical industrial hygiene air samples collected in three US steel mills from 1972 to 1982 were analyzed. The majority of samples were ...

journal_title：Toxicology and industrial health

authors： Hollins D,Burns A,Unice K,Paustenbach DJ

更新日期：2019-11-01 00:00:00

abstract：:The developmental toxicity of 2,4-Pentanedione (2,4-PD; CAS No. 123-54-6), a widely used industrial chemical, was investigated by vapour exposure, because of its widespread use, and potential for human exposure. Timed-pregnant Fischer 344 rats were exposed on gestational days (gd) 6 to 15 inclusive to analytically mea...

journal_title：Toxicology and industrial health

authors： Tyl RW,Ballantyne B,Pritts IM,Garman RH,Fisher LC,France KA,McNeil DJ

更新日期：1990-05-01 00:00:00

abstract：:The human teratogenic potential of chlordiazepoxide is debated. To study the effects on the fetal development of very large doses of chlordiazepoxide that were used for a suicide attempt during pregnancy, self-poisoned pregnant women were identified from patients in a toxicological inpatient clinic in Budapest, Hungar...

journal_title：Toxicology and industrial health

authors： Gidai J,Acs N,Bánhidy F,Czeizel AE

更新日期：2008-02-01 00:00:00

abstract：:The present study investigates the toxic effects of acrylamide (ACR) administered to rats at two doses on (i) oxidative stress and disruption of pro-oxidant/antioxidant balance in hepatic cells and (ii) its correlation with metallothioneins (MTs) genes expression, DNA damage and histomorphological changes. Treated rat...

journal_title：Toxicology and industrial health

authors： Ghorbel I,Elwej A,Chaabene M,Boudawara O,Marrakchi R,Jamoussi K,Boudawara TS,Zeghal N

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:For several decades, there has been increasing evidence for excess incidence of lung cancer among workers in the rubber industry. The purpose of this study was to assess the risk of lung cancer occurrence among Egyptian workers involved in the rubber industry using two circulating protein biomarkers. METHODS...

journal_title：Toxicology and industrial health

authors： Mourad BH

更新日期：2020-04-01 00:00:00

abstract：:Young adult CD-1 male mice were housed in individual cages throughout the study. Groups of 10 to 20 mice were given gradually increasing doses of delta-9-tetrahydrocannabinol (THC) at 6.25 to 25 mg/kg i.p., trifluoperazine (TFP) at 6 to 12 mg/kg p.o., phenobarbital sodium (PS) at 20 to 35 mg/kg p.o., morphine sulfate ...

journal_title：Toxicology and industrial health

authors： Yen-Koo HC,Tocus EC,Balazs T

更新日期：1989-12-01 00:00:00

abstract：:Flight personnel are exposed to cosmic ionizing radiation, chemicals (fuel, jet engine exhausts, cabin air pollutants), electromagnetic fields from cockpit instruments, and disrupted sleep patterns. Only recently has cancer risk among these workers been investigated. With the aim of increasing the precision of risk es...

journal_title：Toxicology and industrial health

authors： Buja A,Lange JH,Perissinotto E,Rausa G,Grigoletto F,Canova C,Mastrangelo G

更新日期：2005-11-01 00:00:00

abstract：:The goal of this study was to explore the impact of 2-deoxglucose or malonate individually or in combination on the level of cell energy (adenosine-5'-triphosphate) and oxidative stress in 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary proliferation in rats. A total of 60 adult female Sprague Dawley rats were r...

journal_title：Toxicology and industrial health

authors： Moselhy SS,Kumosani TA,Al-Malki AL,Naif AA

更新日期：2015-04-01 00:00:00

abstract：:In the last few decades the need for new approaches to assess DNA damage has been increasing due to the implications that different insults on genetic material may have on human health. In this context, the identification of how chemical agents with different mechanisms of action (i.e., antineoplastic drugs) damage DN...

journal_title：Toxicology and industrial health

authors： Mussali-Galante P,Avila-Costa MR,Piñón-Zarate G,Martínez-Levy G,Rodríguez-Lara V,Rojas-Lemus M,Avila-Casado MC,Fortoul TI

更新日期：2005-09-01 00:00:00

abstract：:The Agency for Toxic Substances and Disease Registry (ATSDR) prepared this health consultation to provide support for assessing the public health implications of hazardous chemical exposure, primarily through drinking water, related to releases of chromated copper arsenate (CCA) in the port of Djibouti. CCA from a shi...

journal_title：Toxicology and industrial health

authors： Chou S,Colman J,Tylenda C,De Rosa C

更新日期：2007-05-01 00:00:00

abstract：:This study demonstrates the detection and dynamics of macrocyclic trichothecene mycotoxin (MTM) tissue loading using a commercially available assay in a goat model. The detection of MTMs has been difficult and complex due to the uncertainty of what tissues to examine and when to sample. Twelve goats (two groups of eac...

journal_title：Toxicology and industrial health

authors： Layton RC,Purdy CW,Jumper CA,Straus DC

更新日期：2009-10-01 00:00:00

abstract：:Groups of five male and five female rats were fed diets containing from 0% to 2.5% di(2-ethylhexyl)terephthalate (DEHT) or 1.2% di(2-ethylhexyl)phthalate (DEHP) for 21 days. Feed consumption and body weight gains were collected and, at study termination, animals were examined for alterations in body weight, difference...

journal_title：Toxicology and industrial health

authors： Topping DC,Ford GP,Evans JG,Lake BG,O'Donoghue JL,Lockhart HB Jr

更新日期：1987-06-01 00:00:00

abstract：:The inhalation toxicity of methanol and toluene was investigated in rats. Young Sprague Dawley rats of both sexes were exposed to vapors of methanol (300 ppm, 3000 ppm), toluene (30 ppm, 300 ppm) or methanol/toluene (300/30 ppm, 300/300 ppm, 3000/30 ppm, and 3000/300 ppm) six hrs per day, five days/week for four weeks...

journal_title：Toxicology and industrial health

authors： Poon R,Chu I,Bjarnason S,Potvin M,Vincent R,Miller RB,Valli VE

更新日期：1994-05-01 00:00:00

abstract：:This study aimed to evaluate the extrapulmonary effects of exposure to cigarette smoke (CS) through the analysis of blood components and histopathological examinations of the trachea and diaphragm muscle (DM) in C57BL/6 mice. Thirty-six animals were exposed to six cigarettes per day for 5 days. The mice were divided i...

journal_title：Toxicology and industrial health

authors： Martins TL,Campos KKD,Araújo NPDS,Machado DF,Bezerra FS

更新日期：2017-09-01 00:00:00

abstract：:We recently determined that the metabolism of a series of tumorigenic pyrrolizidine alkaloids resulted in the formation of a set of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-derived DNA adducts. These DHP-derived DNA adducts have been proposed as potential biomarkers of pyrrolizidine alkaloid tumorige...

journal_title：Toxicology and industrial health

authors： Chou MW,Fu PP

更新日期：2006-09-01 00:00:00

abstract：:An investigation was conducted to evaluate the ability of two chelators, deferasirox and desferrioxamine (DFO), in removing cadmium from biological system. The potential efficiency of those chelators were investigated after cadmium administration for 60 days following two dose levels of 20 and 40 mg/kg body weight dai...

journal_title：Toxicology and industrial health

authors： Fatemi SJ,Saljooghi AS,Balooch FD,Iranmanesh M,Golbafan MR

更新日期：2012-02-01 00:00:00

abstract：:The negative health effects caused by lead (Pb) exposure are widely recognized; however, the molecular mechanisms remain unknown. The aim of this study was to assess the effect of occupational Pb exposure on telomere length and to investigate the potential mechanisms leading to telomere shortening. A cohort of 334 mal...

journal_title：Toxicology and industrial health

authors： Pawlas N,Płachetka A,Kozłowska A,Mikołajczyk A,Kasperczyk A,Dobrakowski M,Kasperczyk S

更新日期：2016-12-01 00:00:00

abstract：:The antioxidant power of the so-called antioxidants is negligible because their rate constants and concentrations are too small to compete with the specialized defense enzymes, like superoxide dismutase (SOD), for the reactive oxygen species. In this short review, we present a number of experimental data of our group,...

journal_title：Toxicology and industrial health

authors： Koltover VK

更新日期：2009-05-01 00:00:00

abstract：:In this study, we investigated the protective effect of pentoxifilline (PTX) on smoking-induced damage in rat kidney tissues. Twenty-seven male Wistar rats were used in the study. Animals were divided into three equal groups as follows: Group 1: control group with only normal saline (NS; 0.9% NaCl) injection for 8 wee...

journal_title：Toxicology and industrial health

authors： Ozkurkcugil C,Yilmaz MY,Ozkan L,Kokturk S,Isken T

更新日期：2011-05-01 00:00:00

abstract：:Lead (Pb) is a toxic metal that induces a wide range of biochemical and physiological effects in humans. Oxidative damage has been proposed as a possible mechanism involved in Pb toxicity. The current study was carried out to evaluate the antioxidant activities of zinc (Zn) supplement against lead acetate-induced kidn...

journal_title：Toxicology and industrial health

authors： Soussi A,Gargouri M,El Feki A

更新日期：2018-07-01 00:00:00

abstract：:Natural products possessing antioxidant properties play a very crucial role in ameliorating deleterious effects of reactive oxygen species. This study investigated the chemoprotective properties of methanolic extract of Vernonia amygdalina (MEVA) in an experimental model of hepatic oxidative damage induced by 2-acetyl...

journal_title：Toxicology and industrial health

authors： Adesanoye OA,Adekunle AE,Adewale OB,Mbagwu AE,Delima AA,Adefegha SA,Molehin OR,Farombi EO

更新日期：2016-01-01 00:00:00

abstract：:Exposure to inhalation anesthetics (IAs) has been associated with DNA damage as reflected in the increased frequency of micronuclei (MN) and chromosomal aberrations (CAs). The present study was undertaken to ascertain whether there was any correlation between increased MN and CA and the extent of oxidative stress as w...

journal_title：Toxicology and industrial health

authors： Neghab M,Kargar-Shouroki F,Mozdarani H,Yousefinejad S,Alipour H,Fardid R

更新日期：2020-06-01 00:00:00

abstract：:Penile fracture (PF) is known as a traumatic rupture of the tunica albuginea of corpus cavernosum. In this study, we aimed to investigate the healing influence of topical extra virgin olive oil (EVOO) on PF through evaluating levels of some oxidative stress biomarkers for the first time. Histopathological evaluation w...

journal_title：Toxicology and industrial health

authors： Gunes M,Ozkol H,Pirincci N,Gecit I,Bilici S,Yildirim S

更新日期：2015-08-01 00:00:00

abstract：:The following is a review of some of the work we have done since 2004 regarding the importance of molds and their mycotoxins in the phenomenon of sick building syndrome (SBS). In these studies we showed that the macrocyclic trichothecene mycotoxins (MTM) of Stachybotrys chartarum (SC) are easily dissociated from the s...

journal_title：Toxicology and industrial health

authors： Straus DC

更新日期：2009-10-01 00:00:00

abstract：:As one of the main components of risk assessment, exposure assessment plays a key role in evaluating risk. Many different scenarios can be developed to estimate the risk from exposure to chemicals such as persistent organic pollutants (POPs). The US Food and Drug Administration (FDA)'s Center for Food Safety and Appli...

journal_title：Toxicology and industrial health

authors： Jensen E,Egan S,Canady R,Bolger P

更新日期：2001-06-01 00:00:00